Research ExplorerScientific StaffSamuel Huber Publications

Univ. Prof. Dr. ID: 39065

Samuel Huber

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Publications

  1. 2024

  2. Intestinal epithelia and myeloid immune cells shape colitis severity and colorectal carcinogenesis via High-mobility group box protein 1

    Foelsch, K., Pelczar, P., Zierz, E., Kondratowicz, S., Qi, M., Müller, C., Alawi, M., Huebener, S., Clauditz, T., Gagliani, N., Huber, S. & Huebener, P., 06.08.2024, In: J CROHNS COLITIS. 18, 7, p. 1122-1133 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Gentamicin combination treatment is associated with lower mortality in patients with invasive listeriosis - a retrospective analysis

    Sutter, J. P., Kocheise, L., Kempski, J., Christner, M., Wichmann, D., Pinnschmidt, H., Schmiedel, S., Lohse, A. W., Huber, S. & Brehm, T. T., 08.2024, In: INFECTION. 52, 4, p. 1601-1606 6 p.

    Research output: SCORING: Contribution to journal › Short publication › Research › peer-review

  4. Intergenic risk variant rs56258221 skews the fate of naive CD4+ T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis

    Poch, T., Bahn, J., Casar, C., Krause, J., Evangelakos, I., Gilladi, H., Kunzmann, L. K., Laschtowitz, A., Iuso, N., Schäfer, A-M., Liebig, L. A., Steinmann, S., Sebode, M., Folseraas, T., Engesæter, L. K., Karlsen, T. H., Franke, A., Metabolic Sciences, Max Delbrück Centre for Molecular Medicine in the Helmholtz Association, C., Schlein, C., Galun, E., Huber, S., Lohse, A. W., Gagliani, N., Schwinge, D. & Schramm, C., 16.07.2024, In: CELL REP MED. 5, 7, p. 101620

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. Protective function of sclerosing cholangitis on IBD

    Bedke, T., Stumme, F., Tomczak, M., Steglich, B., Jia, R., Bohmann, S., Wittek, A., Kempski, J., Göke, E., Böttcher, M., Reher, D., Franke, A., Lennartz, M., Clauditz, T., Sauter, G., Fründt, T., Weidemann, S., Tiegs, G., Schramm, C., Gagliani, N., Pelczar, P. & Huber, S., 11.07.2024, In: GUT. 73, 8, p. 1292-1301 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. A Gradient of Intestinal Inflammation in Primary Sclerosing Cholangitis

    Wittek, A., Steglich, B., Casar, C., Seiz, O., Huber, P., Ehlken, H., Reher, D., Wende, S., Bedke, T., Kempski, J., Böttcher, M., Bang, C., Thingholm, L., Krech, T., Lohse, A. W., Sauter, G., Rösch, T., Franke, A., Schramm, C., Gagliani, N., Pelczar, P. & Huber, S., 03.06.2024, In: INFLAMM BOWEL DIS. 30, 6, p. 900-910 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Clinical Presentation and Outcome of Critically Ill Patients with Inflammatory Bowel Disease

    Böttcher, M., Bertram, F., Sabihi, M., Lücke, J., Ahmadi, P., Kluge, S., Roedl, K., Huber, S., Wichmann, D. & Manthey, C. F., 04.2024, In: VISC MED. 40, 2, p. 75-81 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction

    Shiri, A. M., Zhang, T., Bedke, T., Zazara, D. E., Zhao, L., Lücke, J., Sabihi, M., Fazio, A., Zhang, S., Tauriello, D. V. F., Batlle, E., Steglich, B., Kempski, J., Agalioti, T., Nawrocki, M., Xu, Y., Riecken, K., Liebold, I., Brockmann, L., Konczalla, L., Bosurgi, L., Mercanoglu, B., Seeger, P., Küsters, N., Lykoudis, P. M., Heumann, A., Arck, P. C., Fehse, B., Busch, P., Grotelüschen, R., Mann, O., Izbicki, J. R., Hackert, T., Flavell, R. A., Gagliani, N., Giannou, A. D. & Huber, S., 04.2024, In: J HEPATOL. 80, 4, p. 634-644 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. IL-22 promotes liver regeneration after portal vein ligation

    Zhang, T., Seeger, P., Simsek, Y. J., Sabihi, M., Lücke, J., Zazara-Giannou, D., Shiri, M., Kempski, J. M., Blankenburg, T., Zhao, L., Belios, I., Machicote, A. P., Mercanoglu, B., Fard-Aghaie, M., Notz, S. J., Lykoudis, P. M., Kemper, M., Ghadban, T., Mann, O., Hackert, T., Izbicki, J., Renne, T., Huber, S., Giannou, A. & Li, J., 30.03.2024, In: HELIYON. 10, 6, p. e27578

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Mouse models of spontaneous liver and lung metastasis for colorectal cancer

    Lücke, J., Mercanoglu, B., Zhang, T., Zazara, D. E., Zigmond, E., Seeger, P., Mann, O., Izbicki, J. R., Hackert, T., Huber, S. & Giannou, A. D., 15.03.2024, In: STAR PROTOC. 5, 1, p. 102811

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Protocol for generating lung and liver metastasis in mice using models that bypass intravasation

    Lücke, J., Zhang, T., Zazara, D. E., Seeger, P., Izbicki, J. R., Hackert, T., Huber, S. & Giannou, A. D., 15.03.2024, In: STAR PROTOC. 5, 1, p. 102696

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. A protective effect of inflammatory bowel disease on the severity of sclerosing cholangitis

    Stumme, F., Steffens, N., Steglich, B., Mathies, F., Nawrocki, M., Sabihi, M., Soukou-Wargalla, S., Göke, E., Kempski, J., Fründt, T., Weidemann, S., Schramm, C., Gagliani, N., Huber, S. & Bedke, T., 06.03.2024, In: FRONT IMMUNOL. 15, p. 1307297

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. E. coli´s fight against TYROnny: Designing a bacterial strain to tackle tyrosinemia type 1

    Lücke, J. & Huber, S., 03.2024, In: J HEPATOL. 80, 3, p. 394-396 3 p.

    Research output: SCORING: Contribution to journal › Editorial › Research

  14. All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines

    Tian, L-Y., Smit, D. J., Popova, N. V., Horn, S., Velasquez, L. N., Huber, S. & Jucker, M., 11.02.2024, In: INT J MOL SCI. 25, 4, 2168.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Does gamma-glutamyltransferase correlate with liver tumor burden in neuroendocrine tumors?

    Schmidt, B. C., Leiderer, M. T., Amin, T., Viol, F., Huber, S., Henes, F. O. & Schrader, J., 02.2024, In: ENDOCRINE. 83, 2, p. 511-518 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Nmes1 is a novel regulator of mucosal response influencing intestinal healing potential

    Hamley, M., Leyk, S., Casar, C., Liebold, I., Jawazneh, A. A., Lanzloth, C., Böttcher, M., Haas, H., Richardt, U., Rothlin, C. V., Jacobs, T., Huber, S., Adlung, L., Pelczar, P., Henao-Mejia, J. & Bosurgi, L., 02.2024, In: EUR J IMMUNOL. 54, 2, p. e2350434

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Obesity and diabetes mellitus are associated with SARS-CoV-2 outcomes without influencing signature genes of extrapulmonary immune compartments at the RNA level

    Lücke, J., Böttcher, M., Nawrocki, M., Meins, N., Schnell, J., Heinrich, F., Bertram, F., Sabihi, M., Seeger, P., Pfaff, M., Notz, S., Blankenburg, T., Zhang, T., Kempski, J., Reeh, M., Wolter, S., Mann, O., Lütgehetmann, M., Hackert, T., Izbicki, J. R., Duprée, A., Huber, S., Ondruschka, B. & Giannou, A. D., 30.01.2024, In: HELIYON. 10, 2, p. e24508

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Preoperative TIPS and in-hospital mortality in patients with cirrhosis undergoing surgery

    Piecha, F., Vonderlin, J., Frühhaber, F., Graß, J-K., Ozga, A-K., Harberts, A., Benten, D., Hübener, P., Reeh, M., Riedel, C., Bannas, P., Izbicki, J. R., Adam, G., Huber, S., Lohse, A. W. & Kluwe, J., 01.2024, In: JHEP REP. 6, 1, p. 100914

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Corrigendum: PD-1/PD-L1 immune checkpoint therapy demonstrates favorable safety profile in patients with autoimmune and cholestatic liver disease

    Kocheise, L., Piseddu, I., Vonderlin, J., Tjwa, E. T., Buescher, G., Meunier, L., Goeggelmann, P., Fianchi, F., Dumortier, J., Barciela, M. R., Gevers, T. J. G., Beretta-Piccoli, B. T., Londoño, M-C., Frankova, S., Roesner, T., Joerg, V., Schmidt, C., Glaser, F., Sutter, J. P., Fründt, T. W., Lohse, A. W., Huber, S., von Felden, J., Sebode, M. & Schulze, K., 2024, In: FRONT IMMUNOL. 15, p. 1369747

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  20. IFNγ and CTLA-4 Drive Hepatic CD4 T-Cell Tolerance and Protection From Autoimmunity in Mice

    Krzikalla, D., Laschtowitz, A., Leypoldt, L., Gottwick, C., Averhoff, P., Weidemann, S., Lohse, A. W., Huber, S., Schramm, C., Schwinge, D., Herkel, J. & Carambia, A., 2024, In: CELL MOL GASTROENTER. 17, 1, p. 79-91 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. 2023

  22. Protocol for orthotopic single-lung transplantation in mice as a tool for lung metastasis studies

    Giannou, A. D., Ohm, B., Zazara, D. E., Lücke, J., Zhang, T., Sabihi, M., Seeger, P., Oh, J., Grotelüschen, R., Busch, P., Mann, O., Hackert, T., Izbicki, J. R., Yamada, Y., Huber, S. & Jungraithmayr, W., 15.12.2023, In: STAR PROTOC. 4, 4, p. 102701

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Tr1 Cells Emerge and Suppress Effector Th17 Cells in Glomerulonephritis

    Soukou-Wargalla, S., Kilian, C., Velasquez, L. N., Machicote, A., Letz, P., Tran, H. B., Domanig, S., Bertram, F., Stumme, F., Bedke, T., Giannou, A., Kempski, J., Sabihi, M., Song, N., Paust, H-J., Borchers, A., Garcia Perez, L., Pelczar, P., Liu, B., Ergen, C., Steglich, B., Muscate, F., Huber, T. B., Panzer, U., Gagliani, N., Krebs, C. F. & Huber, S., 01.12.2023, In: J IMMUNOL. 211, 11, p. 1669-1679 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. EpCAM-positive circulating tumor cells and serum AFP levels predict outcome after curative resection of hepatocellular carcinoma

    Kocheise, L., Schoenlein, M., Behrends, B., Joerg, V., Casar, C., Fründt, T. W., Renné, T., Heumann, A., Li, J., Huber, S., Lohse, A. W., Pantel, K., Riethdorf, S., Wege, H., Schulze, K. & von Felden, J., 27.11.2023, In: SCI REP-UK. 13, 1, p. 20827

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Myeloid Cell-Specific Deletion of PDGFR-α Promotes Dysbiotic Intestinal Microbiota and thus Increased Colitis Susceptibility

    Dörk, R., Pelczar, P., Shiri, A. M., Volmari, A., Zierz, E., Giannou, A., Böttcher, M., Bosurgi, L., Huber, S. & Manthey, C. F., 24.11.2023, In: J CROHNS COLITIS. 17, 11, p. 1858-1869 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Efficacy and safety of atezolizumab/bevacizumab in patients with HCC after prior systemic therapy: A global, observational study

    Joerg, V., Scheiner, B., D Alessio, A., Fulgenzi, C. A. M., Schönlein, M., Kocheise, L., Lohse, A. W., Huber, S., Wege, H., Kaseb, A., Wang, Y., Mathew, A., Kuang, A., Muzaffar, M., Abugabal, Y. I., Chamseddine, S., Phen, S., Cheon, J., Lee, P-C., Balcar, L., Krall, A., Ang, C., Wu, L., Saeed, A., Huang, Y-H., Bengsch, B., Rimassa, L., Weinmann, A., Stauber, R., Korolewicz, J., Pinter, M., Singal, A. G., Chon, H. J., Pinato, D. J., Schulze, K. & von Felden, J., 01.11.2023, In: HEPATOL COMMUN. 7, 11, e0302.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Comparative analysis of characteristics and outcomes in hospitalized COVID-19 patients infected with different SARS-CoV-2 variants between January 2020 and April 2022 - A retrospective single-center cohort study

    Brehm, T. T., Heyer, A., Woo, M. S., Fischer, M., van der Meirschen, M., Wichmann, D., Jarczak, D., Roedl, K., Schmiedel, S., Addo, M. M., Lütgehetmann, M., Christner, M., Huber, S., Lohse, A. W., Kluge, S. & Schulze Zur Wiesch, J., 11.2023, In: J INFECT PUBLIC HEAL. 16, 11, p. 1806-1812 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis

    Baumdick, M. E., Niehrs, A., Degenhardt, F., Schwerk, M., Hinrichs, O., Jordan-Paiz, A., Padoan, B., Wegner, L. H. M., Schloer, S., Zecher, B. F., Malsy, J., Joshi, V. R., Illig, C., Schröder-Schwarz, J., Möller, K. J., Martin, M., Yuki, Y., Ozawa, M., Sauter, J., Schmidt, A. H., Perez, D., Giannou, A. D., Carrington, M., Davis, R. S., Schumacher, U., Sauter, G., Huber, S., Puelles, V. G., Melling, N., Franke, A., Altfeld, M., Bunders, M. J., Hamburg Intestinal Tissue Study Group & International Inflammatory Bowel Disease Genetics Consortium, 10.2023, In: GASTROENTEROLOGY. 165, 4, p. 946-962.e13

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Stellenwert von Ernährung und Lebensstil

    Bertram, F., Huber, S. & Zyriax, B-C., 10.2023, Schwangerschaft und Stillzeit: Ernährung, Lebensstil, Prävention. Zyriax, B-C. (ed.). 1 ed. München: Elsevier GmbH, p. 1-6 6 p.

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer › peer-review

  30. DISCERN: deep single-cell expression reconstruction for improved cell clustering and cell subtype and state detection

    Hausmann, F., Ergen, C., Khatri, R., Marouf, M., Hänzelmann, S., Gagliani, N., Huber, S., Machart, P. & Bonn, S., 20.09.2023, In: GENOME BIOL. 24, 1, p. 212

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Intestinal IL-1β Plays a Role in Protecting against SARS-CoV-2 Infection

    Lücke, J., Heinrich, F., Malsy, J., Meins, N., Schnell, J., Böttcher, M., Nawrocki, M., Zhang, T., Bertram, F., Sabihi, M., Kempski, J., Blankenburg, T., Duprée, A., Reeh, M., Wolter, S., Mann, O., Izbicki, J. R., Lohse, A. W., Gagliani, N., Lütgehetmann, M., Bunders, M. J., Altfeld, M., Sauter, G., Giannou, A. D., Krasemann, S., Ondruschka, B. & Huber, S., 15.09.2023, In: J IMMUNOL. 211, 6, p. 1052-1061 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Short-term dietary changes can result in mucosal and systemic immune depression

    Siracusa, F., Schaltenberg, N., Kumar, Y., Lesker, T. R., Steglich, B., Liwinski, T., Cortesi, F., Frommann, L., Diercks, B-P., Bönisch, F., Fischer, A. W., Scognamiglio, P., Pauly, M. J., Casar, C., Cohen, Y., Pelczar, P., Agalioti, T., Delfs, F., Worthmann, A., Wahib, R., Jagemann, B., Mittrücker, H-W., Kretz, O., Guse, A. H., Izbicki, J. R., Lassen, K. G., Strowig, T., Schweizer, M., Villablanca, E. J., Elinav, E., Huber, S., Heeren, J. & Gagliani, N., 09.2023, In: NAT IMMUNOL. 24, 9, p. 1473-1486 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

    Kotsiliti, E., Leone, V., Schuehle, S., Govaere, O., Li, H., Wolf, M. J., Horvatic, H., Bierwirth, S., Hundertmark, J., Inverso, D., Zizmare, L., Sarusi-Portuguez, A., Gupta, R., O'Connor, T., Giannou, A. D., Shiri, A. M., Schlesinger, Y., Beccaria, M. G., Rennert, C., Pfister, D., Öllinger, R., Gadjalova, I., Ramadori, P., Rahbari, M., Rahbari, N., Healy, M. E., Fernández-Vaquero, M., Yahoo, N., Janzen, J., Singh, I., Fan, C., Liu, X., Rau, M., Feuchtenberger, M., Schwaneck, E., Wallace, S. J., Cockell, S., Wilson-Kanamori, J., Ramachandran, P., Kho, C., Kendall, T. J., Leblond, A-L., Keppler, S. J., Bielecki, P., Steiger, K., Hofmann, M., Rippe, K., Zitzelsberger, H., Weber, A., Malek, N., Luedde, T., Vucur, M., Augustin, H. G., Flavell, R., Parnas, O., Rad, R., Pabst, O., Henderson, N. C., Huber, S., Macpherson, A., Knolle, P., Claassen, M., Geier, A., Trautwein, C., Unger, K., Elinav, E., Waisman, A., Abdullah, Z., Haller, D., Tacke, F., Anstee, Q. M. & Heikenwalder, M., 08.2023, In: J HEPATOL. 79, 2, p. 296-313 18 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Enabling X-ray fluorescence imaging for in vivo immune cell tracking

    Staufer, T., Körnig, C., Liu, B., Liu, Y., Lanzloth, C., Schmutzler, O., Bedke, T., Machicote, A., Parak, W. J., Feliu, N., Bosurgi, L., Huber, S. & Grüner, F., 17.07.2023, In: SCI REP-UK. 13, 1, p. 11505

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury

    Hackstein, C-P., Spitzer, J., Symeonidis, K., Horvatic, H., Bedke, T., Steglich, B., Klein, S., Assmus, L. M., Odainic, A., Szlapa, J., Kessler, N., Beyer, M., Schmithausen, R., Latz, E., Flavell, R. A., Garbi, N., Kurts, C., Kümmerer, B. M., Trebicka, J., Roers, A., Huber, S., Schmidt, S. V., Knolle, P. A. & Abdullah, Z., 07.2023, In: J HEPATOL. 79, 1, p. 150-166 17 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. Adhesion to laminin-1 and collagen IV induces the formation of Ca2+ microdomains that sensitize mouse T cells for activation

    Weiß, M., Hernandez, L. C., Gil Montoya, D. C., Löhndorf, A., Krüger, A., Kopdag, M., Uebler, L., Landwehr, M., Nawrocki, M., Huber, S., Woelk, L-M., Werner, R., Failla, A. V., Flügel, A., Dupont, G., Guse, A. H. & Diercks, B-P., 20.06.2023, In: SCIENCE SIGNALING. 16, 790, p. eabn9405

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Cell-Autonomous Constitutive gp130 Signaling in T Cells Amplifies TH17 Cell Responses and Causes Severe Lung Inflammation

    Heinig, L. C., Huth, E. V. M., Yan, K., Schumacher, N., Nawrocki, M., Lory, N. C., Bradtke, P., Bertram, T., Rattay, G., Schmid, J., Huber, S., Wiech, T., Biosciences and Medical Biology, Paris Lodron University Salzburg, Salzburg, Austria, D., Rose-John, S. & Mittrücker, H-W., 01.06.2023, In: J IMMUNOL. 210, 11, p. 1717-1727 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Muscle quality determined by computed tomography predicts short-term and long-term survival after liver transplantation

    Molwitz, I., Recklies, F., Stark, M., Horvatits, T., Salamon, J., Huber, S., Fischer, L., Adam, G., Lohse, A. W., Sterneck, M. & Horvatits, K., 10.05.2023, In: SCI REP-UK. 13, 1, p. 7631

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Macrophages and glia are the dominant P2X7-expressing cell types in the gut nervous system-No evidence for the role of neuronal P2X7 receptors in colitis

    Jooss, T., Zhang, J., Zimmer, B., Rezzonico-Jost, T., Rissiek, B., Felipe Pelczar, P., Seehusen, F., Koch-Nolte, F., Magnus, T., Zierler, S., Huber, S., Schemann, M., Grassi, F. & Nicke, A., 04.2023, In: MUCOSAL IMMUNOL. 16, 2, p. 180-193 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. MELD-Lactate Predicts Poor Outcome in Variceal Bleeding in Cirrhosis

    Horvatits, T., Mahmud, N., Serper, M., Seiz, O., Reher, D., Drolz, A., Sarnast, N., Gu, W., Erasmus, H. P., Allo, G., Ferstl, P., Wittmann, S., Piecha, F., Groth, S., Zeuzem, S., Schramm, C., Huber, S., Rösch, T., Lohse, A. W., Trebicka, J., Ogola, G., Asrani, S. K. & Kluwe, J., 03.2023, In: DIGEST DIS SCI. 68, 3, p. 1042-1050 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer

    Tintelnot, J., Xu, Y., Lesker, T. R., Schönlein, M., Konczalla, L., Giannou, A. D., Pelczar, P., Kylies, D., Puelles, V. G., Bielecka, A. A., Peschka, M., Cortesi, F., Riecken, K., Jung, M., Amend, L., Bröring, T. S., Trajkovic-Arsic, M., Siveke, J. T., Renné, T., Zhang, D., Boeck, S., Strowig, T., Uzunoglu, F. G., Güngör, C., Stein, A., Izbicki, J. R., Bokemeyer, C., Sinn, M., Kimmelman, A. C., Huber, S. & Gagliani, N., 03.2023, In: NATURE. 615, 7950, p. 168-174 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Multicytokine-producing CD4+ T cells characterize the livers of patients with NASH

    Woestemeier, A., Scognamiglio, P., Zhao, Y., Wagner, J., Muscate, F., Casar, C., Siracusa, F., Cortesi, F., Agalioti, T., Müller, S., Sagebiel, A., Konczalla, L., Wahib, R., Karstens, K-F., Giannou, A. D., Duprée, A., Wolter, S., Wong, M. N., Mühlig, A. K., Bielecka, A. A., Bansal, V., Zhang, T., Mann, O., Puelles, V. G., Huber, T. B., Lohse, A. W., Izbicki, J. R., Palm, N. W., Bonn, S., Huber, S. & Gagliani, N., 10.01.2023, In: JCI INSIGHT. 8, 1, e153831.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis

    Briukhovetska, D., Suarez-Gosalvez, J., Voigt, C., Markota, A., Giannou, A. D., Schübel, M., Jobst, J., Zhang, T., Dörr, J., Märkl, F., Majed, L., Müller, P. J., May, P., Gottschlich, A., Tokarew, N., Lücke, J., Oner, A., Schwerdtfeger, M., Andreu-Sanz, D., Grünmeier, R., Seifert, M., Michaelides, S., Hristov, M., König, L. M., Cadilha, B. L., Mikhaylov, O., Anders, H-J., Rothenfusser, S., Flavell, R. A., Cerezo-Wallis, D., Tejedo, C., Soengas, M. S., Bald, T., Huber, S., Endres, S. & Kobold, S., 10.01.2023, In: IMMUNITY. 56, 1, p. 143-161.e11

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

    Giannou, A. D., Kempski, J., Shiri, A. M., Lücke, J., Zhang, T., Zhao, L., Zazara, D. E., Cortesi, F., Riecken, K., Amezcua Vesely, M. C., Low, J. S., Xu, H., Kaffe, E., Garcia-Perez, L., Agalioti, T., Yamada, Y., Jungraithmayr, W., Zigmond, E., Karstens, K-F., Steglich, B., Wagner, J., Konczalla, L., Carambia, A., Schulze, K., von Felden, J., May, P., Briukhovetska, D., Bedke, T., Brockmann, L., Starzonek, S., Lange, T., Koch, C., Riethdorf, S., Pelczar, P., Böttcher, M., Sabihi, M., Huber, F. J., Reeh, M., Grass, J. K., Wahib, R., Seese, H., Stüben, B-O., Fard-Aghaie, M., Duprée, A., Scognamiglio, P., Plitzko, G., Meiners, J., Soukou, S., Wittek, A., Manthey, C., Maroulis, I. C., Arck, P. C., Perez, D., Gao, B., Zarogiannis, S. G., Strowig, T., Pasqualini, R., Arap, W., Gosálvez, J. S., Kobold, S., Prinz, I., Guse, A. H., Tachezy, M., Ghadban, T., Heumann, A., Li, J., Melling, N., Mann, O., Izbicki, J. R., Pantel, K., Schumacher, U., Lohse, A. W., Flavell, R. A., Gagliani, N. & Huber, S., 10.01.2023, In: IMMUNITY. 56, 1, p. 125-142.e12

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Cancer associated fibroblasts induce proliferation and therapeutic resistance to everolimus in neuroendocrine tumors through STAT3 activation

    Amin, T., Viol, F., Krause, J., Fahl, M., Eggers, C., Awwad, F., Schmidt, B., Benten, D., Ungefroren, H., Fraune, C., Clauditz, T. S., Sauter, G., Izbicki, J. R., Lohse, A. W., Huber, S. & Schrader, J., 2023, In: NEUROENDOCRINOLOGY. 113, 5, p. 501-518 18 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesis

    Zhang, T., Wahib, R., Zazara, D. E., Lücke, J., Shiri, A. M., Kempski, J., Zhao, L., Agalioti, T., Machicote, A. P., Giannou, O., Belios, I., Jia, R., Zhang, S., Tintelnot, J., Seese, H., Grass, J. K., Mercanoglu, B., Stern, L., Scognamiglio, P., Fard-Aghaie, M., Seeger, P., Wakker, J., Kemper, M., Brunswig, B., Duprée, A., Lykoudis, P. M., Pikouli, A., Giorgakis, E., Stringa, P., Lausada, N., Gentilini, M. V., Gondolesi, G. E., Bachmann, K., Busch, P., Grotelüschen, R., Maroulis, I. C., Arck, P. C., Nakano, R., Thomson, A. W., Ghadban, T., Tachezy, M., Melling, N., Achilles, E-G., Puelles, V. G., Nickel, F., Hackert, T., Mann, O., Izbicki, J. R., Li, J., Gagliani, N., Huber, S. & Giannou, A. D., 2023, In: ONCOIMMUNOLOGY. 12, 1, p. 2269634

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Evidence for broad cross-reactivity of the SARS-CoV-2 NSP12-directed CD4+ T-cell response with pre-primed responses directed against common cold coronaviruses

    Westphal, T., Mader, M., Karsten, H., Cords, L., Knapp, M., Schulte, S., Hermanussen, L., Peine, S., Ditt, V., Grifoni, A., Addo, M. M., Huber, S., Sette, A., Lütgehetmann, M., Pischke, S., Kwok, W. W., Sidney, J. & Schulze Zur Wiesch, J., 2023, In: FRONT IMMUNOL. 14, 1182504.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. IL-22BP controls the progression of liver metastasis in colorectal cancer

    Giannou, A. D., Kempski, J., Zhang, T., Lücke, J., Shiri, A. M., Zazara, D. E., Belios, I., Machicote, A., Seeger, P., Agalioti, T., Tintelnot, J., Sagebiel, A., Tomczak, M., Bauditz, L., Bedke, T., Kocheise, L., Mercanoglu, B., Fard-Aghaie, M., Giorgakis, E., Lykoudis, P. M., Pikouli, A., Grass, J-K., Wahib, R., Bardenhagen, J., Brunswig, B., Heumann, A., Ghadban, T., Duprée, A., Tachezy, M., Melling, N., Arck, P. C., Stringa, P., Gentilini, M. V., Gondolesi, G. E., Nakano, R., Thomson, A. W., Perez, D., Li, J., Mann, O., Izbicki, J. R., Gagliani, N., Maroulis, I. C. & Huber, S., 2023, In: FRONT ONCOL. 13, p. 1170502

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. IRF4 is required for migration of CD4+ T cells to the intestine but not for Th2 and Th17 cell maintenance

    Schmidt, C., Harberts, A., Reimers, D., Bertram, T., Voß, L. C., Schmid, J., Lory, N. C., Spohn, M., Koch-Nolte, F., Huber, S., Raczkowski, F., Breloer, M. & Mittrücker, H-W., 2023, In: FRONT IMMUNOL. 14, p. 1182502

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. PD-1/PD-L1 immune checkpoint therapy demonstrates favorable safety profile in patients with autoimmune and cholestatic liver disease

    Kocheise, L., Piseddu, I., Vonderlin, J., Tjwa, E. T., Buescher, G., Meunier, L., Goeggelmann, P., Fianchi, F., Dumortier, J., Riveiro Barciela, M., Gevers, T. J. G., Terziroli Beretta-Piccoli, B., Londoño, M-C., Frankova, S., Roesner, T., Joerg, V., Schmidt, C., Glaser, F., Sutter, J. P., Fründt, T. W., Lohse, A. W., Huber, S., von Felden, J., Sebode, M. & Schulze, K., 2023, In: FRONT IMMUNOL. 14, p. 1326078

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. TNFα aggravates detrimental effects of SARS-CoV-2 infection in the liver

    Lücke, J., Nawrocki, M., Schnell, J., Meins, N., Heinrich, F., Zhang, T., Bertram, F., Sabihi, M., Böttcher, M., Blankenburg, T., Pfaff, M., Notz, S., Kempski, J., Reeh, M., Wolter, S., Mann, O., Izbicki, J. R., Lütgehetmann, M., Duprée, A., Giannou, A. D., Ondruschka, B. & Huber, S., 2023, In: FRONT IMMUNOL. 14, p. 1151937

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. 2022

  53. A Critical Role of the IL-22-IL-22 Binding Protein Axis in Hepatocellular Carcinoma

    Giannou, A. D., Lücke, J., Kleinschmidt, D., Shiri, A. M., Steglich, B., Nawrocki, M., Zhang, T., Zazara, D. E., Kempski, J., Zhao, L., Giannou, O., Agalioti, T., Brockmann, L., Bertram, F., Sabihi, M., Böttcher, M., Ewald, F., Schulze, K., von Felden, J., Machicote, A., Maroulis, I. C., Arck, P. C., Graß, J-K., Mercanoglu, B., Reeh, M., Wolter, S., Tachezy, M., Seese, H., Theodorakopoulou, M., Lykoudis, P. M., Heumann, A., Uzunoglu, F. G., Ghadban, T., Mann, O., Izbicki, J. R., Li, J., Duprée, A., Melling, N., Gagliani, N. & Huber, S., 07.12.2022, In: CANCERS. 14, 24, 6019.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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