Univ. Prof. Dr. ID: 39065
Samuel Huber
Publications
- 2016
IL-22 dampens the T cell response in experimental malaria
Sellau, J., Alvarado, C. F., Hoenow, S., Mackroth, M. S., Kleinschmidt, D., Huber, S. & Jacobs, T., 17.06.2016, In: SCI REP-UK. 6, p. 28058Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-23 prevents IL-13-dependent tissue repair associated with Ly6C(lo) monocytes in Entamoeba histolytica-induced liver damage
Noll, J., Helk, E., Fehling, H., Bernin, H., Marggraff, C., Jacobs, T., Huber, S., Pelczar, P., Ernst, T., Ittrich, H., Otto, B., Mittrücker, H-W., Hölscher, C., Tacke, F., Bruchhaus, I., Tannich, E. & Lotter, H., 05.2016, In: J HEPATOL. 64, 5, p. 1147-57Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Prenatal Acetaminophen Affects Maternal Immune and Endocrine Adaptation to Pregnancy, Induces Placental Damage, and Impairs Fetal Development in Mice
Thiele, K., Solano, M. E., Huber, S., Flavell, R. A., Kessler, T., Barikbin, R., Jung, R., Karimi, K., Tiegs, G. & Arck, P. C., 10.2015, In: AM J PATHOL. 185, 10, p. 2805-2818Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation
Gagliani, N., Vesely, M. C. A., Iseppon, A., Brockmann, L., Xu, H., Palm, N. W., de Zoete, M. R., Licona-Limón, P., Paiva, R. S., Ching, T., Weaver, C., Zi, X., Pan, X., Fan, R., Garmire, L. X., Cotton, M. J., Drier, Y., Bernstein, B., Geginat, J., Stockinger, B., Esplugues, E., Huber, S. & Flavell, R. A., 09.07.2015, In: NATURE. 523, 7559, p. 221-5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Der klinisch und wissenschaftlich tätige Arzt– aktueller Stand und Perspektiven
Huber, S. & Schramm, C., 02.2015, In: Z GASTROENTEROL. 53, 2, p. 137-8Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Nanoparticle-based autoantigen delivery to Treg-inducing liver sinusoidal endothelial cells enables control of autoimmunity in mice
Carambia, A., Freund, B., Schwinge, D., Bruns, O. T., Salmen, S. C., Ittrich, H., Reimer, R., Heine, M., Huber, S., Waurisch, C., Eychmüller, A., Wraith, D. C., Korn, T., Nielsen, P., Weller, H., Schramm, C., Lüth, S., Lohse, A. W., Heeren, J. & Herkel, J., 21.01.2015, In: J HEPATOL. 62, 6, p. 1349-1356Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intestinal Regulatory CD4+ T cells
Gagliani, N., Huber, S. & Flavell, R. A., 2015, Mucosal Immunology. Mestecky, J., Strober, W., Russell, M. W., Cheroutre, H., Lambrecht, B. N. & Kelsall, B. L. (eds.). 4 ed. Academic Press, Vol. 1-2. p. 777-785 9 p. 38Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2014
TGF-β-dependent induction of CD4⁺CD25⁺Foxp3⁺ Tregs by liver sinusoidal endothelial cells
Carambia, A., Freund, B., Schwinge, D., Heine, M., Laschtowitz, A., Huber, S., Wraith, D. C., Korn, T., Schramm, C., Lohse, A. W., Heeren, J. & Herkel, J., 01.09.2014, In: J HEPATOL. 61, 3, p. 594-9 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Fire Within: Microbes Inflame Tumors
Gagliani, N., Hu, B., Huber, S., Elinav, E. & Flavell, R. A., 08.05.2014, In: CELL. 157, 4, p. 776-783 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Hepatocytes contribute to immune regulation in the liver by activation of the Notch signaling pathway in T cells
Burghardt, S., Erhardt, A., Claass, B., Huber, S., Adler, G., Jacobs, T., Chalaris, A., Schmidt-Arras, D., Rose-John, S., Karimi, K. & Tiegs, G., 01.12.2013, In: J IMMUNOL. 191, 11, p. 5574-82 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Innate immune cells in inflammation and cancer
Nowarski, R., Gagliani, N., Huber, S. & Flavell, R. A., 01.08.2013, In: CANCER IMMUNOL RES. 1, 2, p. 77-84 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research
Inhibition of inflammatory CD4 T cell activity by murine liver sinusoidal endothelial cells
Carambia, A., Frenzel, C., Bruns, O. T., Schwinge, D., Reimer, R., Hohenberg, H., Huber, S., Tiegs, G., Schramm, C., Lohse, A. W. & Herkel, J., 01.01.2013, In: J HEPATOL. 58, 1, p. 112-8 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells.
Gagliani, N., Magnani, C. F., Huber, S., Gianolini, M. E., Pala, M., Licona-Limon, P., Guo, B., Herbert, D. R., Bulfone, A., Trentini, F., Clelia, D. S., Bacchetta, R., Andreani, M., Brockmann, L., Gregori, S., Flavell, R. A. & Roncarolo, M-G., 2013, In: NAT MED. 19, 6, p. 739-746 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer.
Hu, B., Elinav, E., Huber, S., Strowig, T., Hao, L., Hafemann, A., Jin, C., Eisenbarth, S. C. & Flavell, R. A., 2013, In: P NATL ACAD SCI USA. 110, 24, p. 9862-9867 24.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Regulatory T Cell-Derived IL-10 Ameliorates Crescentic GN.
Ostmann, A., Paust, H-J., Panzer, U., Wegscheid, C., Kapffer, S., Huber, S., Flavell, R. A., Erhardt, A. & Tiegs, G., 2013, In: J AM SOC NEPHROL. 24, 6, p. 930-942 13 p., 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
Huber, S., Gagliani, N., Zenewicz, L. A., Huber, F. J., Bosurgi, L., Hu, B., Hedl, M., Zhang, W., O'Connor, W., Murphy, A. J., Valenzuela, D. M., Yancopoulos, G. D., Booth, C. J., Cho, J. H., Ouyang, W., Abraham, C. & Flavell, R. A., 08.11.2012, In: NATURE. 491, 7423, p. 259-263 5 p., 7423.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Intestine: where amazing things happen.
Gagliani, N., Huber, S. & Flavell, R. A., 02.2012, In: CELL RES. 22, 2, p. 277-279 3 p., 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Balancing pro- and anti-inflammatory CD4+ T helper cells in the intestine
Gagliani, N. & Huber, S., 2012, Autoimmune Diseases - Contributing Factors, Specific Cases of Autoimmune Diseases, and Stem Cell and Other Therapies. Intech open Science, p. 51-76 26 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Life, death, and miracles: Th17 cells in the intestine.
Huber, S., Gagliani, N. & Flavell, R. A., 2012, In: EUR J IMMUNOL. 42, 9, p. 2238-2245 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
The induction of mild hypothermia improves systolic function of the resuscitated porcine heart at no further sympathetic activation
Schwarzl, M., Steendijk, P., Huber, S., Truschnig-Wilders, M., Obermayer-Pietsch, B., Maechler, H., Pieske, B. & Post, H., 01.12.2011, In: ACTA PHYSIOL. 203, 4, p. 409-18 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology.
Kamanaka, M., Huber, S., Zenewicz, L. A., Gagliani, N., Rathinam, C., O'Connor, W., Wan, Y. Y., Nakae, S., Iwakura, Y., Hao, L. & Flavell, R. A., 09.05.2011, In: J EXP MED. 208, 5, p. 1027-1040 14 p., 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner
Huber, S., Gagliani, N., Esplugues, E., O'Connor, W., Huber, F. J., Chaudhry, A., Kamanaka, M., Kobayashi, Y., Booth, C. J., Rudensky, A. Y., Roncarolo, M. G., Battaglia, M. & Flavell, R. A., 22.04.2011, In: IMMUNITY. 34, 4, p. 554-565 12 p., 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chronic inflammatory IFN-γ signaling suppresses hepatocarcinogenesis in mice by sensitizing hepatocytes for apoptosis.
Lüth, S., Schrader, J., Zander, S., Carambia, A., Buchkremer, J., Huber, S., Reifenberg, K., Yamamura, K-I., Schirmacher, P., Lohse, A. W. & Herkel, J., 2011, In: CANCER RES. 71, 11, p. 3763-3771 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Control of TH17 cells occurs in the small intestine.
Esplugues, E., Huber, S., Gagliani, N., Hauser, A. E., Town, T., Wan, Y. Y., O'Connor, W., Rongvaux, A., Nico, V. R., Haberman, A. M., Iwakura, Y., Kuchroo, V. K., Kolls, J. K., Bluestone, J. A., Herold, K. C. & Flavell, R. A., 2011, In: NATURE. 475, 7357, p. 514-518 7357.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of activin A in the induction of Foxp3+ and Foxp3- CD4+ regulatory T cells.
Huber, S. & Schramm, C., 2011, In: CRIT REV IMMUNOL. 31, 1, p. 53-60 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
Hu, B., Elinav, E., Huber, S., Booth, C. J., Strowig, T., Jin, C., Eisenbarth, S. C. & Flavell, R. A., 2010, In: P NATL ACAD SCI USA.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Activin a promotes the TGF-beta-induced conversion of CD4+CD25- T cells into Foxp3+ induced regulatory T cells.
Huber, S., Stahl, F. R., Schrader, J., Lüth, S., Presser, K., Carambia, A., Flavell, R. A., Werner, S., Blessing, M., Herkel, J. & Schramm, C., 2009, In: J IMMUNOL. 182, 8, p. 4633-4640 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Coexpression of TGF-beta1 and IL-10 enables regulatory T cells to completely suppress airway hyperreactivity
Presser, K., Schwinge, D., Wegmann, M., Huber, S., Schmitt, S., Quaas, A., Maxeiner, J. H., Finotto, S., Lohse, A. W., Blessing, M. & Schramm, C., 01.12.2008, In: J IMMUNOL. 181, 11, p. 7751-7758 8 p., 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs
Lüth, S., Huber, S., Schramm, C., Buch, T., Zander, S., Stadelmann, C., Brück, W., Wraith, D. C., Herkel, J. & Lohse, A. W., 10.2008, In: J CLIN INVEST. 118, 10, p. 3403-3410 8 p., 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
P38 MAP kinase signaling is required for the conversion of CD4+CD25- T cells into iTreg.
Huber, S., Schrader, J., Fritz, G., Presser, K., Schmitt, S., Waisman, A., Lüth, S., Blessing, M., Herkel, J. & Schramm, C., 2008, In: PLOS ONE. 3, 10, p. 3302 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2006
TGF-beta and CD4+CD25+ regulatory T cells
Huber, S. & Schramm, C., 01.01.2006, In: FRONT BIOSCI-LANDMRK. 11, 1, p. 1014-1023 10 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2004
Cutting edge: TGF-beta signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+CD25+ T cells
Huber, S., Schramm, C., Lehr, H. A., Mann, A., Schmitt, S., Becker, C., Protschka, M., Galle, P. R., Neurath, M. F. & Blessing, M., 01.12.2004, In: J IMMUNOL. 173, 11, p. 6526-31 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling
Becker, C., Fantini, M. C., Schramm, C., Lehr, H. A., Wirtz, S., Nikolaev, A., Burg, J., Strand, S., Kiesslich, R., Huber, S., Ito, H., Nishimoto, N., Yoshizaki, K., Kishimoto, T., Galle, P. R., Blessing, M., Rose-John, S. & Neurath, M. F., 10.2004, In: IMMUNITY. 21, 4, p. 491-501 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TGFbeta regulates the CD4+CD25+ T-cell pool and the expression of Foxp3 in vivo
Schramm, C., Huber, S., Protschka, M., Czochra, P., Burg, J., Schmitt, E., Lohse, A. W., Galle, P. R. & Blessing, M., 09.2004, In: International immunology. 16, 9, p. 1241-1249 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Susceptibility to collagen-induced arthritis is modulated by TGFbeta responsiveness of T cells
Schramm, C., Kriegsmann, J., Protschka, M., Huber, S., Hansen, T., Schmitt, E., Galle, P. R. & Blessing, M., 2004, In: ARTHRITIS RES THER. 6, 2, p. R114-R119Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review