Dr. ID: 64460
Lan Kluwe
Publications
- 2024
PIK3CA Hotspot Mutations in Saliva as a Diagnostic Marker in Oral Squamous Cell Carcinoma Patients
Krüger, K., Grust, A., Muallah, D., Patenge, A., Wikman, H., Mesa, M. M., Knust, E. S., Sartori, A., Smeets, R., Kluwe, L., Friedrich, R. E. & Burg, S., 06.2024, In: ANTICANCER RES. 44, 6, p. 2369-2376 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation
Neyazi, S., Yamazawa, E., Hack, K., Tanaka, S., Nagae, G., Kresbach, C., Umeda, T., Eckhardt, A., Tatsuno, K., Pohl, L., Hana, T., Bockmayr, M., Kim, P., Dorostkar, M. M., Takami, T., Obrecht, D., Takai, K., Suwala, A. K., Komori, T., Godbole, S., Wefers, A. K., Otani, R., Neumann, J. E., Higuchi, F., Schweizer, L., Nakanishi, Y., Monoranu, C-M., Takami, H., Engertsberger, L., Yamada, K., Ruf, V., Nomura, M., Mohme, T., Mukasa, A., Herms, J., Takayanagi, S., Mynarek, M., Matsuura, R., Lamszus, K., Ishii, K., Kluwe, L., Imai, H., von Deimling, A., Koike, T., Benesch, M., Kushihara, Y., Snuderl, M., Nambu, S., Frank, S., Omura, T., Hagel, C., Kugasawa, K., Mautner, V. F., Ichimura, K., Rutkowski, S., Aburatani, H., Saito, N. & Schüller, U., 24.01.2024, In: ACTA NEUROPATHOL. 147, 1, p. 22Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Relative size of fungiform papillae in patients with neurofibromatosis Type 1
Speth, U., Kluwe, L., Gosau, M. & Friedrich, R., 06.2023, In: J STOMATOL ORAL MAXI. 124, 3, p. 101394Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of Dental Pulp Stem Cell Populations in the Teeth of Patients With Neurofibromatosis Type 1 - Therapeutic Potential for Bone Tissue Engineering
Yan, M., Wang, W., Speth, U., Kluwe, L., Fuest, S., Gosau, M., Smeets, R., Feng, H-C. & Friedrich, R. E., 2023, In: IN VIVO. 37, 2, p. 548-558 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Medical Cannabis Alleviates Chronic Neuropathic Pain Effectively and Sustainably without Severe Adverse Effect: A Retrospective Study on 99 Cases
Kluwe, L., Scholze, C., Schmidberg, L. M., Wichmann, J. L., Gemkov, M., Keller, M. J. & Farschtschi, S. C., 2023, In: Medical cannabis and cannabinoids. 6, 1, p. 89-96 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Human dental pulp cells modulate CD8+ T cell proliferation and efficiently degrade extracellular ATP to adenosine in vitro
Ahmadi, P., Yan, M., Bauche, A., Smeets, R., Müller, C. E., Koch-Nolte, F., Haag, F., Fliegert, R., Kluwe, L., Schulze Zur Wiesch, J. & Hartjen, P., 10.2022, In: CELL IMMUNOL. 380, 104589.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tolerance of Human Fibroblasts to Benfo-Oxythiamine In Vitro
Yan, M., Smeets, R., Gosau, M., Vollkommer, T., Fuest, S., Stetzer, E., Kluwe, L., Coy, J. F. & Burg, S., 30.03.2022, In: INT J ENV RES PUB HE. 19, 7, 4112.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Attachment and Osteogenic Potential of Dental Pulp Stem Cells on Non-Thermal Plasma and UV Light Treated Titanium, Zirconia and Modified PEEK Surfaces
Guo, L., Zou, Z., Smeets, R., Kluwe, L., Hartjen, P., Gosau, M. & Henningsen, A., 17.03.2022, In: MATERIALS. 15, 6, 2225.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Effects of a Novel Cold Atmospheric Plasma Treatment of Titanium on the Proliferation and Adhesion Behavior of Fibroblasts
Yan, M., Hartjen, P., Gosau, M., Vollkommer, T., Grust, A. L. C., Fuest, S., Kluwe, L., Burg, S., Smeets, R. & Henningsen, A., 31.12.2021, In: INT J MOL SCI. 23, 1, 420.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
BRCA1 promoter hypermethylation on circulating tumor DNA correlates with improved survival of patients with ovarian cancer
Elazezy, M., Prieske, K., Kluwe, L., Oliveira-Ferrer, L., Peine, S., Müller, V., Woelber, L., Schmalfeldt, B., Pantel, K. & Joosse, S. A., 12.2021, In: MOL ONCOL. 15, 12, p. 3615-3625 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Compare features of human dental pulp cells cultured from pulp tissues with and without cryopreservation
Yan, M., Nada, O. A., Smeets, R., Gosau, M., Friedrich, R. E. & Kluwe, L., 11.2021, In: BIOMED PAP. 165, 4, p. 445-451 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Does a preoperative cone beam CT reduce complication rates in the surgical removal of complex lower third molars? A retrospective study including 486 cases
Klatt, J. C., Sorowka, T., Kluwe, L., Smeets, R., Gosau, M. & Hanken, H., 14.08.2021, In: HEAD FACE MED. 17, 1, 33.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Calcipotriol Enhances Efficacy of Imatinib and Nilotinib on Cells Derived from Plexiform Neurofibroma
Zhao, Y., Yan, M., Mautner, V., Smeets, R., Gosau, M., Kluwe, L. & Friedrich, R. E., 07.2021, In: ANTICANCER RES. 41, 7, p. 3293-3298 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Optimizing Conditions for Spheroid Formation of Dental Pulp Cells in Cell Culture
Zheng, Y., Jiang, L. I., Yan, M., Gosau, M., Smeets, R., Kluwe, L. & Friedrich, R. E., 29.06.2021, In: IN VIVO. 35, 4, p. 1965-1972 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genotype-phenotype correlation in neurofibromatosis type-1: NF1 whole gene deletions lead to high tumor-burden and increased tumor-growth
Well, L., Döbel, K., Kluwe, L., Bannas, P., Farschtschi, S., Adam, G., Mautner, V-F. & Salamon, J., 05.2021, In: PLOS GENET. 17, 5, p. e1009517Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Risk Stratification for Immediate Postoperative Hearing Loss by Preoperative BAER (Brainstem Auditory Evoked Response) and Audiometry in NF2-Associated Vestibular Schwannomas
Gugel, I., Grimm, F., Hartjen, P., Breun, M., Zipfel, J., Liebsch, M., Löwenheim, H., Ernemann, U., Kluwe, L., Mautner, V-F., Tatagiba, M. & Schuhmann, M. U., 18.03.2021, In: CANCERS. 13, 6, 1384.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Empirically downgrading 10 constitutional missense variants of the NF1 gene based on co-existing truncating variants
Kluwe, L. & Mautner, V. F., 02.2021, In: AM J MED GENET A. 185, 2, p. 602-603 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Two simple and inexpensive methods for preparing DNA suitable for digital PCR from a small number of cells in 96-well plates
Zou, Z., Guo, L., Ahmadi, P., Hartjen, P., Gosau, M., Smeets, R. & Kluwe, L., 01.2021, In: J CLIN LAB ANAL. 35, 1, p. e23513Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Copy number variations in primary tumor, serum and lymph node metastasis of bladder cancer patients treated with radical cystectomy
Soave, A., Kluwe, L., Yu, H., Rink, M., Gild, P., Vetterlein, M. W., Marks, P., Sauter, G., Fisch, M., Meyer, C. P., Ludwig, T., Dahlem, R., Minner, S., Pantel, K., Steinbach, B. & Schwarzenbach, H., 09.12.2020, In: SCI REP-UK. 10, 1, p. 21562Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Time Dependency of Non-Thermal Oxygen Plasma and Ultraviolet Irradiation on Cellular Attachment and mRNA Expression of Growth Factors in Osteoblasts on Titanium and Zirconia Surfaces
Guo, L., Zou, Z., Smeets, R., Kluwe, L., Hartjen, P., Cacaci, C., Gosau, M. & Henningsen, A., 14.11.2020, In: INT J MOL SCI. 21, 22Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Assessing the frequency of deep lingual concavities in 826 posterior mandible sockets
Bodart, L., Hanken, H., Smeets, R., Gosau, M., Li, C., Kluwe, L. & Klatt, J., 11.2020, In: J CRANIO MAXILL SURG. 48, 11, p. 1045-1051 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tiao Geng decoction for treating menopausal syndrome exhibits anti-aging effects likely via suppressing ASK1/MKK7/JNK mediated apoptosis in ovariectomized rats
Li, S., Cong, C., Liu, Y., Liu, X., Kluwe, L., Shan, X., Liu, H., Gao, M., Zhao, L., Gao, X. & Xu, L., 28.10.2020, In: J ETHNOPHARMACOL. 261, p. 113061Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical characterization of children and adolescents with NF1 microdeletions
Kehrer-Sawatzki, H., Kluwe, L., Salamon, J., Well, L., Farschtschi, S., Rosenbaum, T. & Mautner, V-F., 10.2020, In: CHILD NERV SYST. 36, 10, p. 2297-2310 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Managing NF2-associated vestibular schwannomas in children and young adults: review of an institutional series regarding effects of surgery and bevacizumab on growth rates, tumor volume, and hearing quality
Gugel, I., Zipfel, J., Hartjen, P., Kluwe, L., Tatagiba, M., Mautner, V-F. & Schuhmann, M. U., 10.2020, In: CHILD NERV SYST. 36, 10, p. 2471-2480 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Presenting symptoms in children with neurofibromatosis type 2
Gugel, I., Grimm, F., Teuber, C., Zipfel, J., Tatagiba, M., Mautner, V-F., Schuhmann, M. U. & Kluwe, L., 10.2020, In: CHILD NERV SYST. 36, 10, p. 2463-2470 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In Vitro Feasibility Analysis of a New Sutureless Wound-Closure System Based on a Temperature-Regulated Laser and a Transparent Collagen Membrane for Laser Tissue Soldering (LTS)
Birkelbach, M. A., Smeets, R., Fiedler, I., Kluwe, L., Wehner, M., Trebst, T. & Hartjen, P., 26.09.2020, In: INT J MOL SCI. 21, 19Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expansion of Human Dental Pulp Cells In Vitro Under Different Cryopreservation Conditions
Yan, M., Nada, O. A., Kluwe, L., Gosau, M., Smeets, R. & Friedrich, R. E., 03.09.2020, In: IN VIVO. 34, 5, p. 2363-2370 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Age at Onset and Presenting Symptoms of Neurofibromatosis Type 2 as Prognostic Factors for Clinical Course of Vestibular Schwannomas
Gugel, I., Grimm, F., Zipfel, J., Teuber, C., Ernemann, U., Kluwe, L., Tatagiba, M., Mautner, V-F. & Schuhmann, M. U., 20.08.2020, In: CANCERS. 12, 9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Null phenotype of neurofibromatosis type 1 in a carrier of a heterozygous atypical NF1 deletion due to mosaicism
Kluwe, L., Friedrich, R. E., Farschtschi, S. C., Hagel, C., Kehrer-Sawatzki, H. & Mautner, V-F., 07.2020, In: HUM MUTAT. 41, 7, p. 1226-1231 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Upregulated immuno-modulator PD-L1 in malignant peripheral nerve sheath tumors provides a potential biomarker and a therapeutic target
Farschtschi, S., Kluwe, L., Park, S-J., Oh, S-J., Mah, N., Mautner, V-F. & Kurtz, A., 07.2020, In: CANCER IMMUNOL IMMUN. 69, 7, p. 1307-1313 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Propranolol Specifically Suppresses the Viability of Tumorous Schwann Cells Derived from Plexiform Neurofibromas In Vitro
Zou, Z., Guo, L., Mautner, V., Smeets, R., Kiuwe, L. & Friedrich, R. E., 02.05.2020, In: IN VIVO. 34, 3, p. 1031-1036 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distinctive low epidermal nerve fiber density in schwannomatosis patients provides a major parameter for diagnosis and differential diagnosis
Farschtschi, S. C., Kluwe, L., Schön, G., Friedrich, R. E., Matschke, J., Glatzel, M., Hagel, C. & Mautner, V-F., 03.2020, In: BRAIN PATHOL. 30, 2, p. 386-391 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inducing differentiation of human dental pulp cells toward acinar-lineage
Yan, M., Kluwe, L., Friedrich, R. E., Li, X., Ren, G., Smeets, R., Gosau, M. & Liu, X., 2020, In: AM J TRANSL RES. 12, 9, p. 5781-5788 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Minimal Effect of Bevacizumab Treatment on Residual Vestibular Schwannomas after Partial Resection in Young Neurofibromatosis Type 2 Patients
Gugel, I., Kluwe, L., Zipfel, J., Teuber, C., Tatagiba, M., Mautner, V-F., Schuhmann, M. U. & Grimm, F., 25.11.2019, In: CANCERS. 11, 12Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cytocompatibility of Titanium, Zirconia and Modified PEEK after Surface Treatment Using UV Light or Non-Thermal Plasma
Guo, L., Smeets, R., Kluwe, L., Hartjen, P., Barbeck, M., Cacaci, C., Gosau, M. & Henningsen, A., 08.11.2019, In: INT J MOL SCI. 20, 22Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of Surgery on Long-Term Results of Hearing in Neurofibromatosis Type-2 Associated Vestibular Schwannomas
Gugel, I., Grimm, F., Liebsch, M., Zipfel, J., Teuber, C., Kluwe, L., Mautner, V-F., Tatagiba, M. & Schuhmann, M. U., 16.09.2019, In: CANCERS. 11, 9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Paeoniflorin inhibits tributyltin chloride-induced apoptosis in hypothalamic neurons via inhibition of MKK4-JNK signaling pathway
Cong, C., Kluwe, L., Li, S., Liu, X., Liu, Y., Liu, H., Gui, W., Liu, T. & Xu, L., 12.06.2019, In: J ETHNOPHARMACOL. 237, p. 1-8 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Vitamin D receptor expression and serum 25(OH)D concentration inversely associates with burden of neurofibromas
Kluwe, L., Hagel, C., Friedrich, R. E., Schnabel, C., Schön, G. & Mautner, V., 05.2019, In: EUR J CANCER PREV. 28, 3, p. 220-224 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Production and Characterization of Porous Fibroin Scaffolds for Regenerative Medical Application
Kopp, A., Smeets, R., Gosau, M., Friedrich, R. E., Fuest, S., Behbahani, M., Barbeck, M., Rutkowski, R., Burg, S., Kluwe, L. & Henningsen, A., 28.04.2019, In: IN VIVO. 33, 3, p. 757-762 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Separating Response of Tumor and non-Tumor Cells to Drug In Vitro by Quantifying a Mutation
Kleinpoppen, M., Moebius, C., Grupp, K., Kluwe, L. & Blessmann, M., 04.2019, In: ANTICANCER RES. 39, 4, p. 1777-1783 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Management of NF2-associated vestibular schwannomas in children and young adults: influence of surgery and clinical factors on tumor volume and growth rate
Gugel, I., Grimm, F., Teuber, C., Kluwe, L., Mautner, V-F., Tatagiba, M. & Schuhmann, M. U., 2019, In: Journal of neurosurgery. Pediatrics. p. 1-9 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Enriching Stem/Progenitor Cells from Dental Pulp Cells by Low-density Culturing
Zhao, Y., Zheng, Y., Eichhorn, W., Klatt, J., Henningsen, A., Kluwe, L., Friedrich, R. E., Gosau, M. & Smeets, R., 28.12.2018, In: IN VIVO. 33, 1, p. 23-29 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Phenotypic and genotypic overlap between mosaic NF2 and schwannomatosis in patients with multiple non-intradermal schwannomas
Kehrer-Sawatzki, H., Kluwe, L., Friedrich, R. E., Summerer, A., Schäfer, E., Wahlländer, U., Matthies, C., Gugel, I., Farschtschi, S., Hagel, C., Cooper, D. N. & Mautner, V-F., 07.2018, In: HUM GENET. 137, 6-7, p. 543-552 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Plasma Electrolytic Oxidation of Titanium Implant Surfaces: Microgroove-Structures Improve Cellular Adhesion and Viability
Hartjen, P., Hoffmann, A., Henningsen, A., Barbeck, M., Kopp, A., Kluwe, L., Precht, C., Quatela, O., Gaudin, R., Heiland, M., Friedrich, R. E., Knipfer, C., Grubeanu, D., Smeets, R. & Jung, O., 25.02.2018, In: IN VIVO. 32, 2, p. 241-247 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cerebrovascular Insult as Presenting Symptom of Neurofibromatosis Type 2 in Children, Adolescents, and Young Adults
Gugel, I., Mautner, V-F., Kluwe, L., Tatagiba, M. S. & Schuhmann, M. U., 2018, In: FRONT NEUROL. 9, p. 733Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Piezosurgery for Sagittal Split Osteotomy: Procedure Duration and Postoperative Sensory Perturbation
Köhnke, R., Kolk, A., Kluwe, L. & Ploder, O., 09.2017, In: J ORAL MAXIL SURG. 75, 9, p. 1941-1947 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lack of evidence for prognostic value of epidermal growth factor receptor intron-1 CA repeats for oral carcinomas
Precht, C., Blessmann, M., Kluwe, L., Scheld, T., Schön, G., Henningsen, A., Pflug, C., Smeets, R., Heiland, M. & Gröbe, A., 04.2017, In: EUR J ORAL SCI. 125, 2, p. 95-101Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Attachment, Viability and Adipodifferentiation of Pre-adipose Cells on Silk Scaffolds with and Without Co-expressed FGF-2 and VEGF.
Hanken, H., Göhler, F., Smeets, R., Heiland, M., Gröbe, A., Friedrich, R., Busch, C. P., Blessmann, M., Kluwe, L. & Hartjen, P., 09.2016, In: IN VIVO. 30, 5, p. 567-72Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effector T cell subclasses associate with tumor burden in neurofibromatosis type 1 patients
Farschtschi, S., Park, S-J., Sawitzki, B., Oh, S-J., Kluwe, L., Mautner, V. F. & Kurtz, A., 09.2016, In: CANCER IMMUNOL IMMUN. 65, 9, p. 1113-1121Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The feasibility of immediately loading dental implants in edentulous jaws
Henningsen, A., Smeets, R., Wahidi, A., Kluwe, L., Kornmann, F., Heiland, M. & Gerlach, T., 08.2016, In: J PERIODONTAL IMPLAN. 46, 4, p. 234-43 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review