Dr. ID: 64460
Lan Kluwe
Publications
- 2016
Postoperative bleeding risk for oral surgery under continued rivaroxaban anticoagulant therapy
Hanken, H., Gröbe, A., Heiland, M., Smeets, R., Kluwe, L., Wikner, J., Koehnke, R., Al-Dam, A. & Eichhorn, W., 07.2016, In: CLIN ORAL INVEST. 20, 6, p. 1279-82Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The importance of nerve microenvironment for schwannoma development
Schulz, A., Büttner, R., Hagel, C., Baader, S. L., Kluwe, L., Salamon, J., Mautner, V-F., Mindos, T., Parkinson, D. B., Gehlhausen, J. R., Clapp, D. W. & Morrison, H., 28.05.2016, In: ACTA NEUROPATHOL. 132, 2, p. 289-307Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel genetic- and cell-based tool for assessing the efficacy and toxicity of anticancer drugs in vitro
Kluwe, L., Wei, J., Alster, I. & Hanken, H., 03.2016, In: BIOMED PAP. 160, 1, p. 64-9 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Optimized in vitro procedure for assessing the cytocompatibility of magnesium-based biomaterials
Jung, O., Smeets, R., Porchetta, D., Kopp, A., Ptock, C., Müller, U., Heiland, M., Schwade, M., Behr, B., Kröger, N., Kluwe, L., Hanken, H. & Hartjen, P., 01.09.2015, In: ACTA BIOMATER. 23, p. 354-363Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased Postoperative Bleeding Risk among Patients with Local Flap Surgery under Continued Clopidogrel Therapy
Eichhorn, W., Haase, M., Kluwe, L., Zeuch, J., Smeets, R., Hanken, H., Wehrmann, M., Gröbe, A., Heiland, M., Birkelbach, M. & Rendenbach, C., 06.08.2015, In: BIOMED RES INT . 2015, p. 120903Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative associations of scalp and body subcutaneous neurofibromas with internal plexiform tumors in neurofibromatosis 1
Jett, K., Nguyen, R., Arman, D., Birch, P., Chohan, H., Farschtschi, S., Fuensterer, C., Kluwe, L., Friedman, J. M. & Mautner, V. F., 07.2015, In: AM J MED GENET A. 167, 7, p. 1518-24 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Is immediate bony microsurgical reconstruction after head and neck tumor ablation associated with a higher rate of local recurrence?
Hanken, H., Wilkens, R., Riecke, B., Al-Dam, A., Tribius, S., Kluwe, L., Smeets, R., Heiland, M., Eichhorn, W. & Gröbe, A., 01.04.2015, In: J CRANIO MAXILL SURG. 43, 3, p. 373-5 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Preclinical assessment of the anticancer drug response of plexiform neurofibroma tissue using primary cultures
Wei, J., Mautner, V. F., Friedrich, R. E. & Kluwe, L., 04.2015, In: J CLIN NEUROL. 11, 2, p. 172-7 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficacy and side-effects of a semi-individualized Chinese herb mixture "Tiáo Gēng Tāng" for menopausal syndrome in China
Jia, M., Kluwe, L., Liu, H-C., Tang, Q-J., Liu, L., Wang, Z-Z., Tian, L-X., Zhao, L., Chen, Y-C., Friedrich, R. E., Sun, Z-J. & Xu, L-W., 21.01.2015, In: IN VIVO. 29, 1, p. 109-15 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lack of evidence for increased postoperative bleeding risk for dental osteotomy with continued aspirin therapy
Hanken, H., Tieck, F., Kluwe, L., Smeets, R., Heiland, M., Precht, C., Eichhorn, M. & Eichhorn, W., 01.01.2015, In: OR SURG OR MED OR PA. 119, 1, p. 17-9 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Postoperative bleeding risk for oral surgery under continued clopidogrel antiplatelet therapy
Gröbe, A., Fraederich, M., Smeets, R., Heiland, M., Kluwe, L., Zeuch, J., Haase, M., Wikner, J., Hanken, H., Semmusch, J., Al-Dam, A. & Eichhorn, W., 01.01.2015, In: BIOMED RES INT . 2015, p. 823651Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Differences of 25-hydroxyvitamin D3 concentrations in children and adults with neurofibromatosis type 1
Schnabel, C., Dahm, S., Streichert, T., Thierfelder, W., Kluwe, L. & Mautner, V. F., 01.05.2014, In: CLIN BIOCHEM. 47, 7-8, p. 560-3 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficacy and selectivity of nilotinib on NF1-associated tumors in vitro
Wei, J., Schnabel, C., Spyra, M., Mautner, V-F., Friedrich, R. E., Hagel, C., Manley, P. W. & Kluwe, L., 01.01.2014, In: J NEURO-ONCOL. 116, 2, p. 231-6 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lack of evidence for predictive and prognostic value of cyclin D1 gene polymorphism CCND1 G870A for oral squamous cell carcinoma
Atac, A., Riecke, B., Assaf, A. T., Gröbe, A., Friedrich, R. E., Heiland, M., Izbicki, J. R., Kluwe, L. & Blessmann, M., 01.01.2014, In: ANTICANCER RES. 34, 1, p. 235-8 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nilotinib is more potent than imatinib for treating plexiform neurofibroma in vitro and in vivo
Wei, J., Freytag, M., Schober, Y., Nockher, W. A., Mautner, V-F., Friedrich, R. E., Manley, P. W., Kluwe, L. & Kurtz, A., 01.01.2014, In: PLOS ONE. 9, 10, p. e107760Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fractal dimension of time-resolved autofluorescence discriminates tumour from healthy tissues in the oral cavity
Klatt, J., Gerich, C. E., Gröbe, A., Opitz, J., Schreiber, J., Hanken, H., Salomon, G., Heiland, M., Kluwe, L. & Blessmann, M., 2014, In: J CRANIO MAXILL SURG. 42, 6, p. 852-854Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunohistochemical and FISH analysis of EGFR and its prognostic value in patients with oral squamous cell carcinoma
Gröbe, A., Eichhorn, W., Fraederich, M., Kluwe, L., Vashist, Y., Wikner, J., Smeets, R., Simon, R., Sauter, G., Heiland, M. & Blessmann, M., 2014, In: J ORAL PATHOL MED. 43, 3, p. 205-10 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lack of evidence for increased risk of postoperative bleeding after cutaneous surgery in the head and neck in patients taking aspirin
Eichhorn, W., Kluwe, L., Heiland, M. & Gröbe, A., 2014, In: BRIT J ORAL MAX SURG. 52, 6, p. 527-529Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
P53 immunohistochemical expression does not correlate with clinical features in 207 carcinomas of the oral cavity and in the head and neck region
Gröbe, A., Hanken, H., Al-Dam, A., Cachovan, G., Smeets, R., Krohn, A., Clauditz, T., Grob, T., Simon, R., Sauter, G., Kluwe, L., Heiland, M. & Blessmann, M., 2014, In: CLIN ORAL INVEST. 18, 1, p. 211-217 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Postoperative bleeding risk for cutaneous surgery in the head and neck region with continued phenprocoumon therapy
Eichhorn, W., Barsukov, E., Al-Dam, A., Gröbe, A., Smeets, R., Eichhorn, M., Heiland, M., Kluwe, L. & Blessmann, M., 2014, In: J CRANIO MAXILL SURG. 42, 5, p. 608-611Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prognostic relevance of circulating tumor cells in blood and disseminated tumor cells in bone marrow of patients with squamous cell carcinoma of the oral cavity
Gröbe, A., Blessmann, M., Hanken, H., Friedrich, R. E., Schön, G., Wikner, J., Harms-Effenberger, K., Kluwe, L., Heiland, M., Pantel, K. & Riethdorf, S., 2014, In: CLIN CANCER RES. 20, 2, p. 425-33 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Amplification of the PPFIA1 gene region on 11q13 in oral squamous cell carcinomas (OSCC)
Blessmann, M., Al-Dam, A., Hanken, H., Assaf, A. T., Riecke, B., Klatt, J., Simon, R., Sauter, G., Heiland, M., Kluwe, L. & Gröbe, A., 01.12.2013, In: J CRANIO MAXILL SURG. 41, 8, p. 845-9 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cardiac characterization of 16 patients with large NF1 gene deletions
Nguyen, R., Mir, T. S., Kluwe, L., Jett, K., Kentsch, M., Müller, G., Kehrer-Sawatzki, H., Friedman, J. M. & Mautner, V-F., 01.10.2013, In: CLIN GENET. 84, 4, p. 344-349 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunohistochemical analysis of p16 expression, HPV infection and its prognostic utility in oral squamous cell carcinoma
Gröbe, A., Hanken, H., Kluwe, L., Schöllchen, M., Tribius, S., Pohlenz, P., Clauditz, T., Grob, T., Simon, R., Sauter, G., Heiland, M. & Blessmann, M., 01.10.2013, In: J ORAL PATHOL MED. 42, 9, p. 676-81 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition
Mohan, P., Castellsague, J., Jiang, J., Allen, K., Chen, H., Nemirovsky, O., Spyra, M., Hu, K., Kluwe, L., Pujana, M. A., Villanueva, A., Mautner, V-F., Keats, J. J., Dunn, S. E., Lazaro, C. & Maxwell, C. A., 01.01.2013, In: ONCOTARGET. 4, 1, p. 80-93 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sensitivity of malignant peripheral nerve sheath tumor cells to TRAIL is augmented by loss of NF1 through modulation of MYC/MAD and is potentiated by curcumin through induction of ROS
Reuss, D. E., Mucha, J., Hagenlocher, C., Ehemann, V., Kluwe, L., Mautner, V-F. & von Deimling, A., 01.01.2013, In: PLOS ONE. 8, 2, p. e57152Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Serum biomarkers for neurofibromatosis type 1 and early detection of malignant peripheral nerve-sheath tumors
Park, S-J., Sawitzki, B., Kluwe, L., Mautner, V-F., Holtkamp, N. & Kurtz, A., 01.01.2013, In: BMC MED. 11, p. 109Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
B-scan ultrasonographic monitoring of orthotopic xenografted plexiform neurofibroma in mice
Gleiss, J., Demestre, M., Spyra, M., Eschenhagen, T., Hagel, C., Mautner, V-F., Kluwe, L. & Friedrich, R. E., 2013, In: IN VIVO. 27, 6, p. 723-7 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
Allelic drop-out, allele imbalance, or loss of heterozygosity?
Kluwe, L., 2012, In: GENE CHROMOSOME CANC. 51, 5, p. 521-523 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of the nonallelic homologous recombination hotspot PRS3 associated with type-3 NF1 deletions.
Zickler, A. M., Hampp, S., Messiaen, L., Bengesser, K., Mussotter, T., Roehl, A. C., Wimmer, K., Mautner, V. F., Kluwe, L., Upadhyaya, M., Pasmant, E., Chuzhanova, N., Kestler, H. A., Högel, J., Legius, E., Claes, K., Cooper, D. N. & Kehrer-Sawatzki, H., 2012, In: HUM MUTAT. 33, 2, p. 372-383 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical presentation, immunohistochemistry and electron microscopy indicate neurofibromatosis type 2-associated gliomas to be spinal ependymomas.
Hagel, C., Stemmer-Rachamimov, A. O., Bornemann, A., Schuhmann, M., Nagel, C., Huson, S., Evans, D. G., Plotkin, S., Matthies, C., Kluwe, L. & Mautner, V. F., 2012, In: NEUROPATHOLOGY. 32, 6, p. 611-616 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dissecting the clinical phenotype associated with mosaic type-2 NF1 microdeletions.
Kehrer-Sawatzki, H., Vogt, J., Mußotter, T., Kluwe, L., Cooper, D. N. & Mautner, V. F., 2012, In: NEUROGENETICS. 13, 3, p. 229-236 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficacy and side effects of chinese herbal medicine for menopausal symptoms: a critical review.
Xu, L-W., Jia, M., Salchow, R., Kentsch, M., Cui, X-J., Deng, H-Y., Sun, Z-J. & Kluwe, L., 2012, In: EVID-BASED COMPL ALT. 2012, p. 568106Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ferritin light chain and squamous cell carcinoma antigen 1 are coreceptors for cellular attachment and entry of hepatitis B virus.
Hao, Z., Zheng, L., Kluwe, L. & Huang, W., 2012, In: INT J NANOMED. 7, p. 827-834Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Growth dynamics of plexiform neurofibromas: a retrospective cohort study of 201 patients with neurofibromatosis 1.
Nguyen, R., Dombi, E., Widemann, B. C., Solomon, J., Fuensterer, C., Kluwe, L., Friedman, J. M. & Mautner, V. F., 2012, In: ORPHANET J RARE DIS. 7, p. 75Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Internal tumor burden in neurofibromatosis Type I patients with large NF1 deletions.
Kluwe, L., Nguyen, R., Vogt, J., Bengesser, K., Mussotter, T., Friedrich, R., Jett, K., Kehrer-Sawatzki, H. & Mautner, V. F., 2012, In: GENE CHROMOSOME CANC. 51, 5, p. 447-451 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Non-coding RNA ANRIL and the number of plexiform neurofibromas in patients with NF1 microdeletions.
Mußotter, T., Kluwe, L., Högel, J., Nguyen, R., Cooper, D. N., Mautner, V. F. & Kehrer-Sawatzki, H., 2012, In: BMC MED GENET. 13, p. 98Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tissue-specific differences in the proportion of mosaic large NF1 deletions are suggestive of a selective growth advantage of hematopoietic del(+/-) stem cells.
Roehl, A. C., Mussotter, T., Cooper, D. N., Kluwe, L., Wimmer, K., Högel, J., Zetzmann, M., Vogt, J., Mautner, V. F. & Kehrer-Sawatzki, H., 2012, In: HUM MUTAT. 33, 3, p. 541-550 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Plexiform neurofibromas in children with neurofibromatosis type 1: frequency and associated clinical deficits.
Nguyen, R., Kluwe, L., Fuensterer, C., Kentsch, M., Friedrich, R. & Mautner, V. F., 01.10.2011, In: J PEDIATR-US. 159, 4, p. 652-652 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Atypical neurofibromas in neurofibromatosis type 1 are premalignant tumors.
Beert, E., Brems, H., Daniëls, B., Ivo, D. W., Frank, V. C., Schoenaers, J., Debiec-Rychter, M., Gevaert, O., Thomas, D. R., Annick, V. D. B., de Ravel, T., Cichowski, K., Kluwe, L., Mautner, V. F., Sciot, R. & Legius, E., 2011, In: GENE CHROMOSOME CANC. 50, 12, p. 1021-1032 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer stem cell-like cells derived from malignant peripheral nerve sheath tumors.
Spyra, M., Kluwe, L., Hagel, C., Nguyen, R., Panse, J., Kurtz, A., Mautner, V. F., Rabkin, S. D. & Demestre, M., 2011, In: PLOS ONE. 6, 6, p. 21099 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chinese herb mix Tiáo-Gēng-Tāng possesses antiaging and antioxidative effects and upregulates expression of estrogen receptors alpha and beta in ovariectomized rats.
Xu, L., Kluwe, L., Zhang, T., Li, S., Mou, Y., Sang, Z., Ma, J., Lu, X. & Sun, Z., 2011, In: BMC COMPLEM ALTERN M. 11, p. 137Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical and healthcare status of patients with neurofibromatosis type 1.
Langenbruch, A. K., Augustin, M., Granström, S., Kluwe, L. & Mautner, V. F., 2011, In: BRIT J DERMATOL. 165, 1, p. 225-227 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Delineation of the clinical phenotype associated with non-mosaic type-2 NF1 deletions: two case reports.
Vogt, J., Nguyen, R., Kluwe, L., Schuhmann, M., Roehl, A. C., Mußotter, T., Cooper, D. N., Mautner, V. F. & Kehrer-Sawatzki, H., 2011, In: J MED CASE REP. 5, 1, p. 577 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effects of splicing mutations on NF2-transcripts: transcript analysis and information theoretic predictions.
Ellis, J. R., Heinrich, B., Mautner, V. F. & Kluwe, L., 2011, In: GENE CHROMOSOME CANC. 50, 8, p. 571-584 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MIA is a potential biomarker for tumour load in neurofibromatosis type 1.
Kolanczyk, M., Mautner, V. F., Kossler, N., Nguyen, R., Kühnisch, J., Zemojtel, T., Jamsheer, A., Wegener, E., Thurisch, B., Tinschert, S., Holtkamp, N., Park, S-J., Birch, P., Kendler, D., Harder, A., Mundlos, S. & Kluwe, L., 2011, In: BMC MED. 9, p. 82Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monozygotic twins discordant for neurofibromatosis type 1 due to a postzygotic NF1 gene mutation.
Vogt, J., Kohlhase, J., Morlot, S., Kluwe, L., Mautner, V. F., Cooper, D. N. & Kehrer-Sawatzki, H., 2011, In: HUM MUTAT. 32, 6, p. 2134-2147 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Analysis of NF1 somatic mutations in cutaneous neurofibromas from patients with high tumor burden.
Thomas, L., Kluwe, L., Chuzhanova, N., Mautner, V. F. & Upadhyaya, M., 2010, In: NEUROGENETICS. 11, 4, p. 391-400 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel third type of recurrent NF1 microdeletion mediated by nonallelic homologous recombination between LRRC37B-containing low-copy repeats in 17q11.2.
Bengesser, K., Cooper, D. N., Steinmann, K., Kluwe, L., Chuzhanova, N. A., Wimmer, K., Tatagiba, M., Tinschert, S., Mautner, V. F. & Kehrer-Sawatzki, H., 2010, In: HUM MUTAT. 31, 6, p. 742-751 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical characterisation of 29 neurofibromatosis type-1 patients with molecularly ascertained 1.4 Mb type-1 NF1 deletions.
Mautner, V. F., Kluwe, L., Friedrich, R., Roehl, A. C., Bammert, S., Högel, J., Spöri, H., Cooper, D. N. & Kehrer-Sawatzki, H., 2010, In: J MED GENET. 47, 9, p. 623-630 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review