Center for Oncology

Publications

  1. 2012
  2. Successful eradication of a FVIII inhibitor in a 60-year-old patient with mild haemophilia A using single-agent prednisolone.

    Holstein, K., Marx, G., Lentz, B., Bokemeyer, C. & Langer, F., 2012, In: HAMOSTASEOLOGIE. 32 Suppl 1, p. 48-51

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Succinate reverses in-vitro platelet inhibition by acetylsalicylic acid and P2Y receptor antagonists.

    Spath, B., Hansen, A., Bokemeyer, C. & Langer, F., 2012, In: PLATELETS. 23, 1, p. 60-68 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Systemtherapie des Leberzellkarzinoms

    Wege, H. & Arnold, D., 2012, In: ONKOLOGE. 18, 7, p. 602-610 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Targeting aurora kinases with danusertib (PHA-739358) inhibits growth of liver metastases from gastroenteropancreatic neuroendocrine tumors in an orthotopic xenograft model.

    Fraedrich, K., Schrader, J., Ittrich, H., von Amsberg, G., Gontarewicz, A., Matzat, V., Kromminga, A., Pace, A., Moll, J., Bläker, M., Lohse, A. W., Hörsch, D., Brümmendorf, T. & Benten, D., 2012, In: CLIN CANCER RES. 18, 17, p. 4621-4632 17.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Targeting Epithelial Growth Factor Receptor (EGFR) With Cetuximab in Combination With Irinotecan as Salvage Treatment in Refractory Gastric Cancer Patients: A Retrospective Analysis and Review of the Literature

    Stein, A., Peinert, S., Al-Batran, S-E. & Arnold, D., 2012, In: Eur J Clin Med Oncol. 4, 1, p. 11-17 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Telomere elongation and clinical response to androgen treatment in a patient with aplastic anemia and a heterozygous hTERT gene mutation.

    Ziegler, P., Schrezenmeier, H., Akkad, J., Brassat, U., Vankann, L., Panse, J., Wilop, S., Balabanov, S., Schwarz, K., Martens, U. M. & Brümmendorf, T. H., 2012, In: ANN HEMATOL. 91, 7, p. 1115-1120 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. TET2 deletions are a recurrent but rare phenomenon in myeloid malignancies and are frequently accompanied by TET2 mutations on the remaining allele.

    Bacher, U., Weissmann, S., Kohlmann, A., Schindela, S., Alpermann, T., Schnittger, S., Kern, W., Haferlach, T. & Haferlach, C., 2012, In: BRIT J HAEMATOL. 156, 1, p. 67-75 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. The benefit of population-based studies for older patients with acute myeloid leukemia.

    Bacher, U. & Haferlach, T., 2012, In: HAEMATOLOGICA. 97, 12, p. 1781-1782 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. The impact of a specific aqua-training for adult haemophilic patients--results of the WATERCISE study (WAT-QoL).

    Mackensen von, S., Eifrig, B., Zäch, D., Kalnins, J., Wieloch, A. & Zeller, W., 2012, In: HAEMOPHILIA. 18, 5, p. 714-721 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. The metabolite 3-hydroxiglutaric acid effectively reduces glioblastoma growth in vivo by affecting the structural integrity of tumor vasculature.

    Oliveira-Ferrer, L., Wellbrock, J., Balabanov, M., Klockow, M., Hauschild, J., Bokemeyer, C., Fiedler, W., Ergun, S. & Schuch, G., 2012, In: CANCER LETT. 326, 2, p. 161-167 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. The novel, orally bioavailable HSP90 inhibitor NVP-HSP990 induces cell cycle arrest and apoptosis in multiple myeloma cells and acts synergistically with melphalan by increased cleavage of caspases.

    Lamottke, B., Kaiser, M., Mieth, M., Heider, U., Gao, Z., Nikolova, Z., Jensen, M. R., Sterz, J., von Metzler, I. & Sezer, O., 2012, In: EUR J HAEMATOL. 88, 5, p. 406-415 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Therapy-related myeloid neoplasms following treatment with radioiodine.

    Schroeder, T., Kuendgen, A., Kayser, S., Kröger, N., Braulke, F., Platzbecker, U., Klärner, V., Zohren, F., Haase, D., Stadler, M., Schlenk, R., Czibere, A. G., Bruns, I., Fenk, R., Gattermann, N., Haas, R., Kobbe, G. & Germing, U., 2012, In: HAEMATOLOGICA. 97, 2, p. 206-212 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. The role of regulatory T cells and TH17 cells in multiple myeloma.

    Braga, W. M. T., Atanackovic, D. & Colleoni, G. W. B., 2012, In: Clin Dev Immunol. 2012, p. 293479

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Three novel cytogenetically cryptic EVI1 rearrangements associated with increased EVI1 expression and poor prognosis identified in 27 acute myeloid leukemia cases.

    Haferlach, C., Bacher, U., Grossmann, V., Schindela, S., Zenger, M., Kohlmann, A., Kern, W., Haferlach, T. & Schnittger, S., 2012, In: GENE CHROMOSOME CANC. 51, 12, p. 1079-1085 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. [Tracheal metastasis of a cutaneous malignant melanoma].

    Ritzel, R. M., Klose, H. & Habermann, C., 2012, In: ROFO-FORTSCHR RONTG. 184, 8, p. 742-743 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Transfusion risk in cancer patients with chemotherapy-induced anemia when initiating darbepoetin alfa therapy at a baseline hemoglobin level of <9 g/dL versus 9 to <10 g/dL versus ≥ 10 g/dL: an exploratory analysis of a phase 3 trial.

    Canon, J-L., Vansteenkiste, J., Hedenus, M., Gascon, P., Bokemeyer, C., Ludwig, H., Vermorken, J., Legg, J., Pujol, B. & Bridges, K., 2012, In: MED ONCOL. 29, 3, p. 2291-2299 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Treatment of Ischemia/Reperfusion Injury of the Kidney with Mesenchymal Stromal Cells

    Lange, C., Zander, A. R. & Westenfelder, C., 2012, Stem Cells and Cancer Stem Cells,Volume 3. Springer Berlin Heidelberg, p. 241-250 10 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  19. Treatment, risk factors, and outcome of adults with relapsed AML after reduced intensity conditioning for allogeneic stem cell transplantation.

    Schmid, C., Labopin, M., Nagler, A., Niederwieser, D., Castagna, L., Tabrizi, R., Stadler, M., Kuball, J., Cornelissen, J., Vorlicek, J., Socié, G., Falda, M., Vindeløv, L., Ljungman, P., Jackson, G., Kröger, N., Rank, A., Polge, E., Rocha, V., Mohty, M., Blood, A. L. W. P. O. T. E. G. F. & Transplantation, M., 2012, In: BLOOD. 119, 6, p. 1599-1606 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature.

    Stein, A., Glockzin, G., Wienke, A., Arnold, D., Edelmann, T., Hildebrandt, B., Hollerbach, S., Illerhaus, G., Königsrainer, A., Richter, M., Schlitt, H. J. & Schmoll, H-J., 2012, In: BMC CANCER. 12, p. 356

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Tumorerfassung

    Frenzel, T., Honecker, F., Krüll, A., Petersen, C. & Yekebas, E. F., 2012, Tumorerfassung: mit Erfassungsbögen und Leitlinien für die interdiszipl. Diagnostik und Therapie. Thieme-Verlag Stuttgart, p. 1-328 328 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  22. Umsetzung integrativer Konzepte - eine Bestandsaufnahme

    Horneber, M., Overkamp, F. & Rostock, M., 2012, In: ONKOLOGIE. 35 Suppl 5, p. 3-11 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Use of CBL exon 8 and 9 mutations in diagnosis of myeloproliferative neoplasms and myelodysplastic/myeloproliferative disorders: an analysis of 636 cases.

    Schnittger, S., Bacher, U., Alpermann, T., Reiter, A., Ulke, M., Dicker, F., Eder, C., Kohlmann, A., Grossmann, V., Kowarsch, A., Kern, W., Haferlach, C. & Haferlach, T., 2012, In: HAEMATOLOGICA. 97, 12, p. 1890-1894 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Validation of CRP as prognostic marker for renal cell carcinoma in a large series of patients.

    Steffens, S., Köhler, A., Rudolph, R., Eggers, H., Seidel, C., Janssen, M., Wegener, G., Schrader, M., Kuczyk, M. A. & Schrader, A. J., 2012, In: BMC CANCER. 12, p. 399

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Will SNPs be useful predictors of normal tissue radiosensitivity in the future?

    Andreassen, C. N., Dikomey, E., Parliament, M. & West, C. M. L., 2012, In: RADIOTHER ONCOL. 105, 3, p. 283-288 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. 2011
  27. Characterization of Enterobacter cloacae pneumonia: a single-center retrospective analysis.

    Hennigs, J. K., Baumann, H. J., Schmiedel, S., Tennstedt, P., Sobottka, I., Bokemeyer, C., Kluge, S. & Klose, H., 01.12.2011, In: LUNG. 189, 6, p. 475-483 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Preclinical and clinical activity of sunitinib in patients with cisplatin-refractory or multiply relapsed germ cell tumors: a Canadian Urologic Oncology Group/German Testicular Cancer Study Group cooperative study

    Oechsle, K., Honecker, F., Cheng, T., Mayer, F., Czaykowski, P., Winquist, E., Wood, L., Fenner, M., Glaesener, S., Hartmann, J. T., Chi, K., Bokemeyer, C. & Kollmannsberger, C., 01.12.2011, In: ANN ONCOL. 22, 12, p. 2654-60 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Sequence therapy in patients with metastatic renal cell carcinoma: comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors

    Busch, J., Seidel, C., Kempkensteffen, C., Johannsen, M., Wolff, I., Hinz, S., Magheli, A., Miller, K., Grünwald, V. & Weikert, S., 12.2011, In: EUR UROL. 60, 6, p. 1163-70 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Klassifikation und Differentialdiagnose der pulmonalen Hypertonie

    Hennigs, J. K., Baumann, H. J., Lüneburg, N., Kluge, S., Sydow, K. & Klose, H., 01.11.2011, In: Atemwegs LungenKh. 37, p. 443-448 5 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  31. Modern imaging techniques during therapy in patients with multiple myeloma

    Horger, M., Weisel, K., Bares, R., Ernemann, U., Claussen, C. D., Lichy, M. & Fenchel, M., 01.10.2011, In: ACTA RADIOL. 52, 8, p. 881-8 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  32. Efficient synthesis and applications of peptides containing adenylylated tyrosine residues

    Smit, C., Blümer, J., Eerland, M. F., Albers, M. F., Goody, R. S., Itzen, A. & Hedberg, C., 19.09.2011, In: ANGEW CHEM INT EDIT. 50, 39, p. 9200-4 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. EAU guidelines on testicular cancer: 2011 update

    Albers, P., Albrecht, W., Algaba, F., Bokemeyer, C., Cohn-Cedermark, G., Fizazi, K., Horwich, A., Laguna, M. P. & European Association of Urology, 01.08.2011, In: EUR UROL. 60, 2, p. 304-319 16 p., 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Final results of the European Advanced Renal Cell Carcinoma Sorafenib (EU-ARCCS) expanded-access study: a large open-label study in diverse community settings.

    Beck, J., Procopio, G., Bajetta, E., Keilholz, U., Negrier, S., Szczylik, C., Bokemeyer, C., Bracarda, S., Richel, D. J., Staehler, M., Strauss, U. P., Mersmann, S., Burock, K. & Escudier, B., 01.08.2011, In: ANN ONCOL. 22, 8, p. 1812-1823 12 p., 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Treatment of patients with relapsed and/or cisplatin-refractory metastatic germ cell tumours: an update.

    Koychev, D., Oechsle, K., Bokemeyer, C. & Honecker, F., 01.08.2011, In: INT J ANDROL. 34, 4 Pt 2, p. 266-273 4 Pt 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Response of renal lesions during systemic treatment with sunitinib in patients with metastatic renal cell carcinoma: a single center experience with 14 patients

    Seidel, C., Fenner, M., Merseburger, A. S., Reuter, C., Ivanyi, P., Länger, F., Ganser, A. & Grünwald, V., 06.2011, In: WORLD J UROL. 29, 3, p. 355-60 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Actual and predicted survival time of patients with spinal metastases of lung cancer: evaluation of the robustness of the Tokuhashi score.

    Hessler, C., Vettorazzi, E., Madert, J., Bokemeyer, C. & Panse, J., 20.05.2011, In: SPINE. 36, 12, p. 983-989 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells

    Nilsson, S., Huelsenbeck, J. & Fritz, G., 01.05.2011, In: CANCER LETT. 304, 1, p. 60-9 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Einsatz von mTOR-Inhibitoren bei soliden Tumoren

    Seidel, C. & Grünwald, V., 04.2011, In: Med Monatsschr Pharm. 34, 4, p. 116-26; quiz 127-8

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Purification of CD4+ T cells for adoptive immunotherapy after allogeneic hematopoietic stem cell transplantation

    Klyuchnikov, E., Sputtek, A., Slesarchuk, O., Lioznov, M., Stübig, T., Bacher, U., Amtsfeld, G., Merle, E., Reckhaus, M-L., Fehse, B., Wolschke, C., Adjalle, R., Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 01.03.2011, In: BIOL BLOOD MARROW TR. 17, 3, p. 374-383 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Limited clinical relevance of imaging techniques in the follow-up of patients with advanced chronic lymphocytic leukemia: results of a meta-analysis

    Eichhorst, B. F., Fischer, K., Fink, A-M., Elter, T., Wendtner, C. M., Goede, V., Bergmann, M., Stilgenbauer, S., Hopfinger, G., Ritgen, M., Bahlo, J., Busch, R., Hallek, M., German CLL Study Group (GCLLSG) & Bokemeyer, C., 10.02.2011, In: BLOOD. 117, 6, p. 1817-21 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells

    Bauerschmidt, C., Woodcock, M., Stevens, D. L., Hill, M. A., Rothkamm, K. & Helleday, T., 01.02.2011, In: EXP CELL RES. 317, 3, p. 330-7 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Expression of TGF-β receptor ALK-5 has a negative impact on outcome of patients with acute myeloid leukemia

    Otten, J., Schmitz, L., Vettorazzi, E., Schultze, A., Marx, A. H., Simon, R., Krauter, J., Loges, S., Sauter, G., Bokemeyer, C. & Fiedler, W., 01.02.2011, In: LEUKEMIA. 25, 2, p. 375-9 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Tomotherapy in locally advanced head and neck cancer-does it reduce xerostomia?

    Goy, Y., Prosch, C., Bajrovic, A., Matnjani, G., Krüll, A., Petersen, C., Albers, D., Rapp, W. & Tribius, S., 02.2011, In: RADIOTHER ONCOL. 98, Suppl. 1, p. S34

    Research output: SCORING: Contribution to journalConference abstract in journalResearchpeer-review

  45. Classical homeopathy in the treatment of cancer patients - a prospective observational study of two independent cohorts

    Rostock, M., Naumann, J., Guethlin, C., Guenther, L., Bartsch, H. H. & Walach, H., 17.01.2011, In: BMC CANCER. 11, p. 19

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells

    Michaelis, M., Rothweiler, F., Barth, S., Cinatl, J., van Rikxoort, M., Löschmann, N., Voges, Y., Breitling, R., von Deimling, A., Rödel, F., Riecken, K., Fehse, B., Mack, E., Stiewe, T., Doerr, H. W., Speidel, D., Cinatl, J. & Riecken, K., 01.01.2011, In: CELL DEATH DIS. 2, p. e243

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Miliary never-smoking adenocarcinoma of the lung: strong association with epidermal growth factor receptor exon 19 deletion.

    Laack, E., Simon, R., Regier, M., Andritzky, B., Tennstedt, P., Habermann, C., Verth, C. Z., Thoem, I., Grob, T., Sauter, G. & Bokemeyer, C., 01.01.2011, In: J THORAC ONCOL. 6, 1, p. 199-202 4 p., 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. The versatile Legionella effector protein DrrA

    Goody, R. S., Schoebel, S., Oesterlin, L. K., Blümer, J., Peters, H., Blankenfeldt, W. & Itzen, A., 01.2011, In: Commun Integr Biol. 4, 1, p. 72-4 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. [18F]fluoroethylcholine-PET/CT imaging for radiation treatment planning of recurrent and primary prostate cancer with dose escalation to PET/CT-positive lymph nodes.

    Würschmidt, F., Petersen, C., Wahl, A., Dahle, J. & Kretschmer, M., 2011, In: RADIAT ONCOL. 6, p. 44

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. 7q21-rs6964587 and breast cancer risk: an extended case-control study by the Breast Cancer Association Consortium.

    Milne, R. L., Lorenzo-Bermejo, J., Burwinkel, B., Malats, N., Arias, J. I., Zamora, M. P., Benítez, J., Humphreys, M. K., García-Closas, M., Chanock, S. J., Lissowska, J., Sherman, M. E., Mannermaa, A., Kataja, V., Kosma, V-M., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., Anton-Culver, H., Ziogas, A., Devilee, P., Asperen, V., Christie, J., Tollenaar, R. A. E. M., Seynaeve, C., Hall, P., Czene, K., Liu, J., Irwanto, A. K., Kang, D., Yoo, K-Y., Noh, D-Y., Couch, F. J., Olson, J. E., Wang, X., Fredericksen, Z., Nordestgaard, B. G., Bojesen, S. E., Flyger, H., Margolin, S., Lindblom, A., Fasching, P. A., Schulz-Wendtland, R., Ekici, A. B., Beckmann, M. W., Wang-Gohrke, S., Shen, C-Y., Yu, J-C., Hsu, H-M., Wu, P-E., Giles, G. G., Severi, G., Baglietto, L., English, D. R., Cox, A., Brock, I., Elliott, G., Reed, M. W. R., Beesley, J., Chen, X., Investigators, K., Group, AOCS., Fletcher, O., Gibson, L., Isabel, D. S. S., Peto, J., Frank, B., Heil, J., Meindl, A., Chang-Claude, J., Hein, R., Flesch-Janys, D., Flesch-Janys, D., Southey, M. C., Smith, L., Apicella, C., Hopper, J. L., Dunning, A. M., Pooley, K. A., Pharoah, P. D. P., Hamann, U., Pesch, B., Ko, Y-D., Network, GENICA., Easton, D. F. & Chenevix-Trench, G., 2011, In: J MED GENET. 48, 10, p. 698-702 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Abcg2 overexpression represents a novel mechanism for acquired resistance to the multi-kinase inhibitor Danusertib in BCR-ABL-positive cells in vitro.

    Balabanov, S., Gontarewicz, A., von Amsberg, G., Raddrizzani, L., Balabanov, M., Bosotti, R., Moll, J., Jost, E., Barett, C., Rohe, I., Bokemeyer, C., Holyoake, T. L. & Brümmendorf, T., 2011, In: PLOS ONE. 6, 4, p. 19164 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. A copy number repeat polymorphism in the transactivation domain of the CEPBA gene is possibly associated with a protective effect against acquired CEBPA mutations: an analysis in 1135 patients with AML and 187 healthy controls.

    Schnittger, S., Bacher, U., Eder, C., Lohse, P., Haferlach, C., Kern, W. & Haferlach, T., 2011, In: EXP HEMATOL. 39, 1, p. 87-94 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review