Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature.

Alexander Stein; Gabriel Glockzin; Andreas Wienke; Dirk Arnold; Thomas Edelmann; Bert Hildebrandt; Stephan Hollerbach; Gerald Illerhaus; Alfred Königsrainer; Michael Richter; Hans J Schlitt; Hans-Joachim Schmoll

doi:10.1186/1471-2407-12-356

Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature.

Alexander Stein
Gabriel Glockzin
Andreas Wienke
Dirk Arnold
Thomas Edelmann
Bert Hildebrandt
Stephan Hollerbach
Gerald Illerhaus
Alfred Königsrainer
Michael Richter
Hans J Schlitt
Hans-Joachim Schmoll

Related Research units

II. Department of Medicine

Abstract

More than half of patients with colorectal cancer will develop metastatic disease either evident at the time of initial diagnosis or during their course of disease. Besides multidisciplinary management further treatment intensification is warranted to improve the still limited prognosis.

Bibliographical data

Original language	English
ISSN	1471-2407
DOIs	https://doi.org/10.1186/1471-2407-12-356
Publication status	Published - 2012

pubmed	22897915