Research ExplorerResearch UnitsCenter for Diagnostics Publications

Center for Diagnostics

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Publications

  1. 2020

  2. Implications of SARS-CoV-2 Infection and COVID-19 Crisis on Clinical Cancer Care: Report of the University Cancer Center Hamburg: Report of the University Cancer Center Hamburg

    Weisel, K. C., Morgner-Miehlke, A., Petersen, C., Fiedler, W., Block, A., Schafhausen, P., Knobloch, J. K. & Bokemeyer, C., 07.05.2020, In: ONCOL RES TREAT. 43, 6, p. 307-313 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  3. Revisited: Therapeutic and toxic blood concentrations of more than 1100 drugs and other xenobiotics

    Schulz, M., Schmoldt, A., Andresen-Streichert, H. & Iwersen-Bergmann, S., 06.05.2020, In: CRIT CARE. 24, 1, p. 195

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  4. Case report: acute abdominal pain in a 37-year-old patient and the consequences for his family

    Niemeyer, E., Mofid, H., Zornig, C., Burandt, E-C., Stein, A., Block, A. & Volk, A. E., 03.05.2020, In: BMC GASTROENTEROL. 20, 1, p. 129

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. Pik3ca mutations significantly enhance the growth of Shh medulloblastoma and lead to metastatic tumour growth in a novel mouse model

    Niesen, J., Ohli, J., Sedlacik, J., Dührsen, L., Hellwig, M., Spohn, M., Holsten, T. & Schüller, U., 01.05.2020, In: CANCER LETT. 477, p. 10-18 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Risk factors for different intestinal pathogens among patients with traveler's diarrhea: A retrospective analysis at a German travel clinic (2009-2017)

    Brehm, T. T., Lütgehetmann, M., Tannich, E., Addo, M. M., Lohse, A. W., Rolling, T. & Vinnemeier, C. D., 01.05.2020, In: TRAVEL MED INFECT DI. 37, p. 101706

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. 64th Annual Congress of the Gesellschaft für Thrombose- und Hämostaseforschung e.V. in Bremen (Part II)

    Langer, F. & Renné, T., 05.2020, In: HAMOSTASEOLOGIE. 40, 2, p. 143-144 2 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  8. An 8-Year-Old Girl with Posterior Fossa Mass

    Ruf, V. C., Schöler, A., Capper, D., Arzberger, T., Herms, J. & Schüller, U., 05.2020, In: BRAIN PATHOL. 30, 3, p. 713-714 2 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. A novel mouse model of phospholipase A2 receptor 1-associated membranous nephropathy mimics podocyte injury in patients

    Meyer-Schwesinger, C., Tomas, N. M., Dehde, S., Seifert, L., Hermans-Borgmeyer, I., Wiech, T., Koch-Nolte, F., Huber, T. B. & Zahner, G., 05.2020, In: KIDNEY INT. 97, 5, p. 913-919 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Cases of asphyxia in children and adolescents: a retrospective analysis of fatal accidents, suicides, and homicides from 1998 to 2017 in Hamburg, Germany

    Mosek, D. P., Sperhake, J. P., Edler, C., Püschel, K. & Schröder, A. S., 05.2020, In: INT J LEGAL MED. 134, 3, p. 1073-1081 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Clinical characteristics and outcomes of invasive Lomentospora prolificans infections: Analysis of patients in the FungiScope® registry

    Jenks, J. D., Seidel, D., Cornely, O. A., Chen, S., van Hal, S., Kauffman, C., Miceli, M. H., Heinemann, M., Christner, M., Jover Sáenz, A., Burchardt, A., Kemmerling, B., Herbrecht, R., Steinmann, J., Shoham, S., Gräber, S., Pagano, L., Deeren, D., Slavin, M. A. & Hoenigl, M., 05.2020, In: MYCOSES. 63, 5, p. 437-442 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Death abroad: Medico-legal autopsy results of repatriated corpses: A retrospective analysis of cases at the Department of Legal Medicine in Frankfurt am Main

    Holz, F., Saulich, M. F., Schröder, A. S., Birngruber, C. G., Verhoff, M. A. & Plenzig, S., 05.2020, In: FORENSIC SCI INT. 310, p. 110257

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Detection of C. difficile toxin as a model assay for performing fully automated high-throughput RT-PCR on clinical stool samples

    Eigner, U., Nörz, D., Reucher, S., Furrer, J., Sun, J., Chu, K., Kolb, M., Hefner, N., Pfefferle, S. & Lütgehetmann, M., 05.2020, In: J MICROBIOL METH. 172, p. 105882

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Detection of doxorubicin, cisplatin and therapeutic antibodies in formalin-fixed paraffin-embedded human cancer cells

    Böckelmann, L., Starzonek, C., Niehoff, A-C., Karst, U., Thomale, J., Schlüter, H., Bokemeyer, C., Aigner, A. & Schumacher, U., 05.2020, In: HISTOCHEM CELL BIOL. 153, 5, p. 367-377 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis

    Marques, A. R. A., Di Spiezio, A., Thießen, N., Schmidt, L., Grötzinger, J., Lüllmann-Rauch, R., Damme, M., Storck, S. E., Pietrzik, C. U., Fogh, J., Bär, J., Mikhaylova, M., Glatzel, M., Bassal, M., Bartsch, U. & Saftig, P., 05.2020, In: AUTOPHAGY. 16, 5, p. 811-825 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Guiding Opioid Administration by 3 Different Analgesia Nociception Monitoring Indices During General Anesthesia Alters Intraoperative Sufentanil Consumption and Stress Hormone Release: A Randomized Controlled Pilot Study

    Funcke, S., Pinnschmidt, H. O., Wesseler, S., Brinkmann, C., Beyer, B., Jazbutyte, V., Behem, C. R., Trepte, C. & Nitzschke, R., 05.2020, In: ANESTH ANALG. 130, 5, p. 1264-1273 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. High homogeneity of mismatch repair deficiency in advanced prostate cancer

    Fraune, C., Simon, R., Höflmayer, D., Möller, K., Dum, D., Büscheck, F., Hube-Magg, C., Makrypidi-Fraune, G., Kluth, M., Hinsch, A., Burandt, E., Clauditz, T. S., Wilczak, W., Sauter, G. & Steurer, S., 05.2020, In: VIRCHOWS ARCH. 476, 5, p. 745-752 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance

    Melcher, V., Graf, M., Interlandi, M., Moreno, N., de Faria, F. W., Kim, S. N., Kastrati, D., Korbanka, S., Alfert, A., Gerß, J., Meyer Zu Hörste, G., Hartmann, W., Frühwald, M. C., Dugas, M., Schüller, U., Hasselblatt, M., Albert, T. K. & Kerl, K., 05.2020, In: ACTA NEUROPATHOL. 139, 5, p. 913-936 24 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. MMR deficiency in urothelial carcinoma of the bladder presents with temporal and spatial homogeneity throughout the tumor mass

    Fraune, C., Simon, R., Hube-Magg, C., Makrypidi-Fraune, G., Kähler, C., Kluth, M., Höflmayer, D., Büscheck, F., Dum, D., Luebke, A. M., Burandt, E., Clauditz, T. S., Wilczak, W., Sauter, G. & Steurer, S., 05.2020, In: UROL ONCOL-SEMIN ORI. 38, 5, p. 488-495 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Preferential sensitivity to HDAC inhibitors in tumors with CREBBP mutation

    Hellwig, M., Merk, D. J., Lutz, B. & Schüller, U., 05.2020, In: CANCER GENE THER. 27, 5, p. 294-300 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. The effect of bleaching agents on the DNA analysis of bloodstains on different floor coverings

    Edler, C., Krebs, O., Gehl, A., Palatzke, K., Tiedemann, N., Schröder, A. S. & Klein, A., 05.2020, In: INT J LEGAL MED. 134, 3, p. 921-927 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Investigating the suitability of high-resolution mass spectrometry for newborn screening: identification of hemoglobinopathies and β-thalassemias in dried blood spots

    Wiesinger, T., Mechtler, T., Schwarz, M., Xie, X., Grosse, R., Nieves Cobos, P., Kasper, D. & Lukacs, Z., 28.04.2020, In: CLIN CHEM LAB MED. 58, 5, p. 810-816 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Poji:a Fiji-based tool for analysis of podosomes and associated proteins

    Herzog, R., van den Dries, K., Cervero, P. & Linder, S., 28.04.2020, In: J CELL SCI. 133, 8

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Relapsing cutaneous leishmaniasis in a patient requiring TNF-α-inhibitor Infliximab for Takayasu-arteritis: Case report and review of the literature

    Heinemann, M., Omansen, T. F., Hennigs, A., Völker, K., Menz, A., Addo, M. M. & Schmiedel, S., 28.04.2020, In: TRAVEL MED INFECT DI. 37, p. 101700

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  25. Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion

    Horstmann, J. A., Lunelli, M., Cazzola, H., Heidemann, J., Kühne, C., Steffen, P., Szefs, S., Rossi, C., Lokareddy, R. K., Wang, C., Lemaire, L., Hughes, K. T., Uetrecht, C., Schlüter, H., Grassl, G. A., Stradal, T. E. B., Rossez, Y., Kolbe, M. & Erhardt, M., 24.04.2020, In: NAT COMMUN. 11, 1, p. 2013

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Acute-on-chronic liver failure alters meropenem pharmacokinetics in critically ill patients with continuous hemodialysis: an observational study

    Grensemann, J., Busse, D., König, C., Roedl, K., Jäger, W., Jarczak, D., Iwersen-Bergmann, S., Manthey, C., Kluge, S., Kloft, C. & Fuhrmann, V., 22.04.2020, In: ANN INTENSIVE CARE. 10, 1, p. 48

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Susceptibility to cellular stress in PS1 mutant N2a cells is associated with mitochondrial defects and altered calcium homeostasis

    Rojas-Charry, L., Calero-Martinez, S., Morganti, C., Morciano, G., Park, K., Hagel, C., Marciniak, S. J., Glatzel, M., Pinton, P. & Sepulveda-Falla, D., 15.04.2020, In: SCI REP-UK. 10, 1, p. 6455

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets

    Deppermann, C., Kratofil, R. M., Peiseler, M., David, B. A., Zindel, J., Castanheira, F. V. E. S., van der Wal, F., Carestia, A., Jenne, C. N., Marth, J. D. & Kubes, P., 06.04.2020, In: J EXP MED. 217, 4

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. The Tumor Suppressor TFF1 Occurs in Different Forms and Interacts with Multiple Partners in the Human Gastric Mucus Barrier: Indications for Diverse Protective Functions

    Heuer, J., Heuer, F., Stürmer, R., Harder, S., Schlüter, H., Braga Emidio, N., Muttenthaler, M., Jechorek, D., Meyer, F. & Hoffmann, W., 04.04.2020, In: INT J MOL SCI. 21, 7

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Chorioangiom der Plazenta – eine seltene Ursache fetaler High-Output-Herzinsuffizienz

    Ziemann, M., Apostolidou, S., Dum, D., Hecher, K., Singer, D. & Tavares de Sousa, M., 04.2020, In: Z GEBURTSH NEONATOL. 224, 2, p. 103-106 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  31. Diagnostic strategy for females suspected of Fabry disease

    Balendran, S., Oliva, P., Sansen, S., Mechtler, T. P., Streubel, B., Cobos, P. N., Lukacs, Z. & Kasper, D. C., 04.2020, In: CLIN GENET. 97, 4, p. 655-660 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma

    Struve, N., Binder, Z. A., Stead, L. F., Brend, T., Bagley, S. J., Faulkner, C., Ott, L., Müller-Goebel, J., Weik, A-S., Hoffer, K., Krug, L., Rieckmann, T., Bußmann, L., Henze, M., Morrissette, J. J. D., Kurian, K. M., Schüller, U., Petersen, C., Rothkamm, K., O Rourke, D. M., Short, S. C. & Kriegs, M., 04.2020, In: ONCOGENE. 39, 15, p. 3041-3055 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Emergence of coagulase-negative staphylococci

    Becker, K., Both, A., Weißelberg, S., Heilmann, C. & Rohde, H., 04.2020, In: EXPERT REV ANTI-INFE. 18, 4, p. 349-366 18 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  34. Impact of Adherence to Multidisciplinary Recommendations for Adjuvant Treatment in Radical Prostatectomy Patients With High Risk of Recurrence

    Knipper, S., Sadat-Khonsari, M., Boehm, K., Mandel, P., Budäus, L., Steuber, T., Maurer, T., Heinzer, H., Schwarz, R., Sauter, G., Tilki, D., Huland, H. & Graefen, M., 04.2020, In: CLIN GENITOURIN CANC. 18, 2, p. e112-e121

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Infection-induced epigenetic changes and their impact on the pathogenesis of diseases

    Fischer, N., 04.2020, In: SEMIN IMMUNOPATHOL. 42, 2, p. 127-130 4 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  36. Irisin: Still chasing shadows

    Albrecht, E., Schering, L., Buck, F., Vlach, K., Schober, H-C., Drevon, C. A. & Maak, S., 04.2020, In: MOL METAB. 34, p. 124-135 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Modulation of S. epidermidis-induced innate immune responses in neonatal whole blood

    Tröger, B., Heidemann, M., Osthues, I., Knaack, D., Göpel, W., Herting, E., Knobloch, J. K-M. & Härtel, C., 04.2020, In: J MICROBIOL IMMUNOL. 53, 2, p. 240-249 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Plasma total prion protein as a potential biomarker for neurodegenerative dementia: diagnostic accuracy in the spectrum of prion diseases

    Llorens, F., Villar-Piqué, A., Schmitz, M., Diaz-Lucena, D., Wohlhage, M., Hermann, P., Goebel, S., Schmidt, I., Glatzel, M., Hauw, J-J., Sikorska, B., Liberski, P. P., Riggert, J., Ferrer, I. & Zerr, I., 04.2020, In: NEUROPATH APPL NEURO. 46, 3, p. 240-254 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Rapid identification of the vanA/vanB resistance determinant in Enterococcus sp. from blood cultures using the Cepheid Xpert vanA/vanB cartridge system

    Both, A., Berneking, L., Berinson, B., Lütgehetmann, M., Christner, M., Aepfelbacher, M. & Rohde, H., 04.2020, In: DIAGN MICR INFEC DIS. 96, 4, p. 114977

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Ten Years of Urgent Care of Ruptured Abdominal Aortic Aneurysms in a High-Volume-Center

    Behrendt, C-A., Kölbel, T., Larena-Avellaneda, A., Heidemann, F., Veliqi, E., Rieß, H. C., Kluge, S., Wachs, C., Püschel, K. & Debus, E. S., 04.2020, In: ANN VASC SURG. 64, p. 88-98 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Transfer of Clinical Reasoning Trained With a Serious Game to Comparable Clinical Problems: A Prospective Randomized Study

    Middeke, A., Anders, S., Raupach, T. & Schuelper, N., 04.2020, In: SIMUL HEALTHC. 15, 2, p. 75-81 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Loss of p16 and high Ki67 labeling index is associated with poor outcome in esophageal carcinoma

    Jacobsen, F., Kohsar, J., Gebauer, F., Kluth, M., Hube-Magg, C., Simon, R., Bockhorn, M., Hinsch, A., Burandt, E., Lübke, A. M., Steurer, S., Tachezy, M., Sauter, G., Izbicki, J. R., Wilczak, W. & Melling, N., 24.03.2020, In: ONCOTARGET. 11, 12, p. 1007-1016 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Biperiden and mepazine effectively inhibit MALT1 activity and tumor growth in pancreatic cancer

    Konczalla, L., Perez, D. R., Wenzel, N., Wolters-Eisfeld, G., Klemp, C., Lüddeke, J., Wolski, A., Landschulze, D., Meier, C., Buchholz, A., Yao, D., Hofmann, B. T., Graß, J. K., Spriestersbach, S. L., Grupp, K., Schumacher, U., Betzel, C., Kapis, S., Nuguid, T., Steinberg, P., Püschel, K., Sauter, G., Bockhorn, M., Uzunoglu, F. G., Izbicki, J. R., Güngör, C. & El Gammal, A. T., 15.03.2020, In: INT J CANCER. 146, 6, p. 1618-1630 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. hGFAP-Positive Stem Cells Depend on Brg1 for Proper Formation of Cerebral and Cerebellar Structures

    Holdhof, D., Schoof, M., Hellwig, M., Holdhof, N. H., Niesen, J. & Schüller, U., 14.03.2020, In: CEREB CORTEX. 30, 3, p. 1382-1392 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Digital PCR Assays for Precise Quantification of CD19-CAR-T Cells after Treatment with Axicabtagene Ciloleucel

    Fehse, B., Badbaran, A., Berger, C., Sonntag, T., Riecken, K., Geffken, M., Kröger, N. & Ayuk, F. A., 13.03.2020, In: MOL THER-METH CLIN D. 16, p. 172-178 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. FASN Is a Biomarker Enriched in Malignant Glioma-Derived Extracellular Vesicles

    Ricklefs, F. L., Maire, C. L., Matschke, J., Dührsen, L., Sauvigny, T., Holz, M., Kolbe, K., Peine, S., Herold-Mende, C., Carter, B., Chiocca, E. A., Lawler, S. E., Westphal, M. & Lamszus, K., 12.03.2020, In: INT J MOL SCI. 21, 6

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Merkel Cell Polyomavirus DNA Replication Induces Senescence in Human Dermal Fibroblasts in a Kap1/Trim28-Dependent Manner

    Siebels, S., Czech-Sioli, M., Spohn, M., Schmidt, C., Theiss, J., Indenbirken, D., Günther, T., Grundhoff, A. & Fischer, N., 10.03.2020, In: MBIO. 11, 2

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape

    Mohme, M., Maire, C. L., Schliffke, S., Joosse, S. A., Alawi, M., Matschke, J., Schüller, U., Dierlamm, J., Martens, T., Pantel, K., Riethdorf, S., Lamszus, K. & Westphal, M., 09.03.2020, In: ACTA NEUROPATHOL COM. 8, 1, 28.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion

    Fraune, C., Harms, L., Büscheck, F., Höflmayer, D., Tsourlakis, M. C., Clauditz, T. S., Simon, R., Möller, K., Luebke, A. M., Möller-Koop, C., Steurer, S., Hube-Magg, C., Sauter, G., Weidemann, S., Lebok, P., Dum, D., Kind, S., Minner, S., Izbicki, J. R., Schlomm, T., Huland, H., Heinzer, H., Burandt, E., Haese, A., Graefen, M. & Schroeder, C., 06.03.2020, In: MOL MED. 26, 1, p. 24

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

    Noubouossie, D., Henderson, M. W., Mooberry, M. J., Ilich, A., Ellsworth, P., Piegore, M., Skinner, S. C., Pawlinski, R., Welsby, I., Renné, T., Hoffman, M., Monroe, D. M. & Key, N. S., 05.03.2020, In: BLOOD. 135, 10, p. 755-765 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. Evaluation of a quantitative RT-PCR assay for the detection of the emerging coronavirus SARS-CoV-2 using a high throughput system

    Pfefferle, S., Reucher, S., Nörz, D. S. & Lütgehetmann, M., 04.03.2020, In: EUROSURVEILLANCE. 25, 9

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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