Department of Stem Cell Transplantation
Publications
- 2007
Dualism of mixed chimerism between hematopoiesis and stroma in chronic idiopathic myelofibrosis after allogeneic stem cell transplantation.
Thiele, J., Varus, E., Siebolts, U., Kvasnicka, H. M., Wickenhauser, C., Metz, K. A., Beelen, D. W., Ditschkowski, M., Zander, A. R. & Kröger, N., 2007, In: HISTOL HISTOPATHOL. 22, 4, p. 365-372 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Farber disease: clinical presentation, pathogenesis and a new approach to treatment.
Ehlert, K., Frosch, M., Fehse, N., Zander, A. R., Roth, J. & Vormoor, J., 2007, In: PEDIATR RHEUMATOL. 5, p. 15Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene expression profiling for the diagnosis of acute leukaemia.
Haferlach, T., Kohlmann, A., Bacher, U., Schnittger, S., Haferlach, C. & Kern, W., 2007, In: BRIT J CANCER. 96, 4, p. 535-540 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations.
Metzner, A., Horstmann, M., Fehse, B., Ortmeyer, G., Niemeyer, C. M., Stocking, C., Mayr, G. W. & Jücker, M., 2007, In: GENE THER. 14, 8, p. 699-703 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Insertional mutagenesis by replication-deficient retroviral vectors encoding the large T oncogene.
Li, Z., Kustikova, O. S., Kamino, K., Neumann, T., Rhein, M., Grassman, E., Fehse, B. & Baum, C., 2007, In: ANN NY ACAD SCI. 1106, p. 95-113Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Insight into the molecular pathogenesis of myeloid malignancies.
Haferlach, T., Bacher, U., Haferlach, C., Kern, W. & Schnittger, S., 2007, In: CURR OPIN HEMATOL. 14, 2, p. 90-97 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
JAK2 seems to be a typical cooperating mutation in therapy-related t(8;21)/ AML1-ETO-positive AML.
Schnittger, S., Bacher, U., Kern, W., Haferlach, C. & Haferlach, T., 2007, In: LEUKEMIA. 21, 1, p. 183-184 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
JAK2V617F as progression marker in CMPD and as cooperative mutation in AML with trisomy 8 and t(8;21): a comparative study on 1103 CMPD and 269 AML cases.
Schnittger, S., Bacher, U., Kern, W., Haferlach, T. & Haferlach, C., 2007, In: LEUKEMIA. 21, 8, p. 1843-1845 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
L1 is associated with favorable outcome in neuroblastomas in contrast to adult tumors.
Wachowiak, R., Fiegel, H., Kaifi, J., Quaas, A., Krickhahn, A., Schurr, P., Erttmann, R., Schachner, M., Kluth, D., Sauter, G. & Izbicki, J. R., 2007, In: ANN SURG ONCOL. 14, 12, p. 3575-3580 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-term safety of filgrastim (rhG-CSF) administration: application of haematopoietic growth factors in healthy individuals.
Bacher, U. & Zander, A. R., 2007, In: BRIT J HAEMATOL. 137, 1, p. 78-80 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mini-Midi-Maxi? How to harness the graft-versus-myeloma effect and target molecular remission after allogeneic stem cell transplantation.
Kröger, N., 2007, In: LEUKEMIA. 21, 9, p. 1851-1858 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Modulation of Ca2+ entry and plasma membrane potential by human TRPM4b.
Fliegert, R., Glassmeier, G., Schmid, F., Cornils, K., Genisyuerek, S., Harneit, A., Schwarz, J. R. & Guse, A. H., 2007, In: FEBS J. 274, 3, p. 704-713 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monitoring of the JAK2-V617F mutation by highly sensitive quantitative real-time PCR after allogeneic stem cell transplantation in patients with myelofibrosis.
Kröger, N., Badbaran, A., Holler, E., Hahn, J., Kobbe, G., Bornhäuser, M., Reiter, A., Zabelina, T., Zander, A. R. & Fehse, B., 2007, In: BLOOD. 109, 3, p. 1316-1321 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monitoring serum free light chains in patients with multiple myeloma who achieved negative immunofixation after allogeneic stem cell transplantation.
Mösbauer, U., Ayuketang Ayuk, F., Schieder, H., Lioznov, M., Zander, A. R. & Kröger, N., 2007, In: HAEMATOLOGICA. 92, 2, p. 275-276 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Non-hematopoietic bone marrow cells for regenerative medicine.
Lange, C., Tögel, F., Jaquet, K., Ittrich, H., Westenfelder, C. & Zander, AR., 2007, Stem cells and their potential for clinical application. Bilko et al. (Ed.) (ed.). NATO ASI Series, 105 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Peripheral blood or bone marrow cells in reduced-intensity or myeloablative conditioning allogeneic HLA identical sibling donor transplantation for multiple myeloma.
Gahrton, G., Iacobelli, S., Bandini, G., Björkstrand, B., Corradini, P., Crawley, C., Hegenbart, U., Morgan, G., Kröger, N., Schattenberg, A., Schönland, S. O., Verdonck, L. F., Volin, L., de Witte, T. & Niederwieser, D., 2007, In: HAEMATOLOGICA. 92, 11, p. 1513-1518 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pharmacogenetic analysis of liver toxicity after busulfan/cyclophosphamide-based allogeneic hematopoietic stem cell transplantation.
Goekkurt, E., Stoehlmacher, J., Stueber, C., Wolschke, C., Eiermann, T., Iacobelli, S., Zander, A. R., Ehninger, G. & Kröger, N., 2007, In: ANTICANCER RES. 27, 6, p. 4377-4380 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Progress in characterization, preparation and clinical applications of non-hematopoietic stem cells, 29-30 September 2006, Tübingen, Germany
Schäfer, R., Dominici, M., Müller, I., Dazzi, F., Bieback, K., Godthardt, K., Le Blanc, K., Meisel, R., Pochampally, R., Richter, R., Skutella, T., Steinhoff, G., Mitterberger, M., Wendel, H., Wiskirchen, J., Handgretinger, R. & Northoff, H., 2007, In: CYTOTHERAPY. 9, 4, p. 397-405 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Proteomic patterns predict acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Weissinger, E. M., Schiffer, E., Hertenstein, B., Ferrara, J. L., Holler, E., Stadler, M., Kolb, H-J., Zander, A. R., Zürbig, P., Kellmann, M. & Ganser, A., 2007, In: BLOOD. 109, 12, p. 5511-5519 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rapid regression of bone marrow fibrosis after dose-reduced allogeneic stem cell transplantation in patients with primary myelofibrosis.
Kröger, N., Thiele, J., Zander, A. R., Schwerdtfeger, R., Kobbe, G., Bornhäuser, M., Bethge, W., Schubert, J., de Witte, T. & Kvasnicka, H. M., 2007, In: EXP HEMATOL. 35, 11, p. 1719-1722 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rare CBFB-MYH11 fusion transcripts in AML with inv(16)/t(16;16) are associated with therapy-related AML M4eo, atypical cytomorphology, atypical immunophenotype, atypical additional chromosomal rearrangements and low white blood cell count: a study on 162 patients.
Schnittger, S., Bacher, U., Haferlach, C., Kern, W. & Haferlach, T., 2007, In: LEUKEMIA. 21, 4, p. 725-731 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Recovery of peripheral blood lymphocytes in patients with hematological diseases after allogenic non-relative transplantation of hemopoietic stem cells]
Vavilov, V. N., Zander, A. R. & Afanas'iev, B. V., 2007, In: TERAPEVT ARKH. 79, 7, p. 44-47 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Remarkable leukemogenic potency and quality of a constitutively active neurotrophin receptor, deltaTrkA.
Meyer, J., Rhein, M., Schiedlmeier, B., Kustikova, O., Rudolph, C., Kamino, K., Neumann, T., Yang, M., Wahlers, A., Fehse, B., Reuther, G. W., Schlegelberger, B., Ganser, A., Baum, C. & Li, Z., 2007, In: LEUKEMIA. 21, 10, p. 2171-2180 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.
Kustikova, O. S., Geiger, H., Li, Z., Brugman, M. H., Chambers, S. M., Shaw, C. A., Pike-Overzet, K., de Ridder, D., Staal, F. J. T., von Keudell, G., Cornils, K., Nattamai, K. J., Modlich, U., Wagemaker, G., Goodell, M. A., Fehse, B. & Baum, C., 2007, In: BLOOD. 109, 5, p. 1897-1907 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Simplified protocol to isolate, purify, and culture expand mesenchymal stem cells.
Schrepfer, S., Deuse, T., Lange, C., Katzenberg, R., Reichenspurner, H., Robbins, R. C. & Pelletier, M. P., 2007, In: STEM CELLS DEV. 16, 1, p. 105-107 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The association between neuropsychological impairment, self-perceived cognitive deficits, fatigue and health related quality of life in breast cancer survivors following standard adjuvant versus high-dose chemotherapy.
Mehnert, A., Scherwath, A., Schirmer, L., Schleimer, B., Petersen-Ewert, C., Schulz-Kindermann, F., Zander, A. R. & Koch-Gromus, U., 2007, In: PATIENT EDUC COUNS. 66, 1, p. 108-118 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2006
Haploidentical stem cell transplantation in patients with pediatric solid tumors: preliminary results of a pilot study and analysis of graft versus tumor effects
Lang, P., Pfeiffer, M., Müller, I., Schumm, M., Ebinger, M., Koscielniak, E., Feuchtinger, T., Föll, J., Martin, D. & Handgretinger, R., 03.11.2006, In: KLIN PADIATR. 218, 6, p. 321-6 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In vitro analysis of multipotent mesenchymal stromal cells as potential cellular therapeutics in neurometabolic diseases in pediatric patients
Müller, I., Kustermann-Kuhn, B., Holzwarth, C., Isensee, G., Vaegler, M., Harzer, K., Krägeloh-Mann, I., Handgretinger, R. & Bruchelt, G., 10.2006, In: Experimental hematology. 34, 10, p. 1413-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bovine herpesvirus 4 based vector interaction with liver cells in vitro and in vivo
Donofrio, G., Martignani, E., Poli, E., Lange, C., Martini, F. M., Cavirani, S., Cabassi, C. S., Taddei, S. & Flammini, C. F., 01.09.2006, In: J VIROL METHODS. 136, 1-2, p. 126-36 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased alpha2,6-sialylation of surface proteins on tolerogenic, immature dendritic cells and regulatory T cells
Jenner, J., Kerst, G., Handgretinger, R. & Müller, I., 09.2006, In: Experimental hematology. 34, 9, p. 1212-8 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM
Müller, I., Kordowich, S., Holzwarth, C., Spano, C., Isensee, G., Staiber, A., Viebahn, S., Gieseke, F., Langer, H., Gawaz, M. P., Horwitz, E. M., Conte, P., Handgretinger, R. & Dominici, M., 01.01.2006, In: CYTOTHERAPY. 8, 5, p. 437-44 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Transfer › peer-review
Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A.
Zur Stadt, U., Beutel, K., Kolberg, S., Schneppenheim, R., Kabisch, H., Janka, G. & Hennies, H. C., 01.2006, In: HUM MUTAT. 27, 1, p. 62-68 7 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic and syngeneic hematopoietic cell transplantation in patients with amyloid light-chain amyloidosis: a report from the European Group for Blood and Marrow Transplantation.
Schönland, S. O., Lokhorst, H., Buzyn, A., Leblond, V., Hegenbart, U., Bandini, G., Campbell, A., Carreras, E., Ferrant, A., Grommisch, L., Jacobs, P., Kröger, N., Giorgio, L. N., Russell, N., Zachee, P., Goldschmidt, H., Iacobelli, S., Niederwieser, D. & Gahrton, G., 2006, In: BLOOD. 107, 6, p. 2578-2584 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic haematopoietic cell transplantation for chronic myelogenous leukaemia in the era of imatinib: a retrospective multicentre study.
Bornhäuser, M., Kröger, N., Schwerdtfeger, R., Schafer-Eckart, K., Sayer, H. G., Scheid, C., Stelljes, M., Kienast, J., Mundhenk, P., Fruehauf, S., Kiehl, M. G., Wandt, H., Theuser, C., Ehninger, G. & Zander, A. R., 2006, In: EUR J HAEMATOL. 76, 1, p. 9-17 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic stem-cell transplantation in patients with refractory acute leukemia: a long-term follow-up.
Oyekunle, A. A., Kröger, N., Zabelina, T., Ayuketang Ayuk, F., Schieder, H., Renges, H., Fehse, N., Waschke, O., Fehse, B., Kabisch, H. & Zander, A. R., 2006, In: BONE MARROW TRANSPL. 37, 1, p. 45-50 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Autologous stem cell transplantation for therapy-related acute myeloid leukemia and myelodysplastic syndrome.
Kröger, N., Brand, R., van Biezen, A., Cahn, J-Y., Slavin, S., Blaise, D., Sierra, J., Zander, A. R., Niederwieser, D. & de Witte, T., 2006, In: BONE MARROW TRANSPL. 37, 2, p. 183-189 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bortezomib after dose-reduced allogeneic stem cell transplantation for multiple myeloma to enhance or maintain remission status.
Kröger, N., Zabelina, T., Ayuketang Ayuk, F., Atanackovic, D., Schieder, H., Renges, H. & Zander, A. R., 2006, In: EXP HEMATOL. 34, 6, p. 770-775 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD34(+)-selected stem cell boost for delayed or insufficient engraftment after allogeneic stem cell transplantation.
Oyekunle, A., Koehl, U., Schieder, H., Ayuketang Ayuk, F., Renges, H., Fehse, N., Zabelina, T., Fehse, B., Klingebiel, T., Sputtek, A., Zander, A. R. & Kröger, N., 2006, In: CYTOTHERAPY. 8, 4, p. 375-380 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cell growth and differentiation of different hepatic cells isolated from fetal rat liver in vitro.
Fiegel, H. C., Bruns, H., Höper, C., Lioznov, M. & Kluth, D., 2006, In: TISSUE ENG. 12, 1, p. 123-130 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparable results in patients with acute lymphoblastic leukemia after related and unrelated stem cell transplantation.
Dahlke, J., Kröger, N., Zabelina, T., Ayuketang Ayuk, F., Wolschke, C., Renges, H-H., Krüger, W., Kruell, A., Hinke, A., Erttmann, R., Kabisch, H. & Zander, A. R., 2006, In: BONE MARROW TRANSPL. 37, 2, p. 155-163 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of flow cytometry vs. a haematology cell analyser-based method to guide the optimal time-point for peripheral blood stem cell apheresis.
Gutensohn, K., Magens, M., Krüger, W., Kröger, N. & Kühnl, P., 2006, In: VOX SANG. 90, 1, p. 53-58 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dynamic expression of LIM cofactors in the developing mouse neural tube.
Ostendorff, H. P., Tursun, B., Cornils, K., Schlüter, A., Drung, A., Güngör, C. & Bach, I., 2006, In: DEV DYNAM. 235, 3, p. 786-791 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fetal and adult liver stem cells for liver regeneration and tissue engineering.
Fiegel, H. C., Lange, C., Kneser, U., Lambrecht, W., Zander, A. R., Rogiers, X. & Kluth, D., 2006, In: J CELL MOL MED. 10, 3, p. 577-587 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatocytic differentiation of mesenchymal stem cells in cocultures with fetal liver cells.
Lange, C., Bruns, H., Kluth, D., Zander, A. R. & Fiegel, H-C., 2006, In: WORLD J GASTROENTERO. 12, 15, p. 2394-2397 15.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hyaluronate and its receptors in bone marrow.
Schade, U. M., Nehmann, N., Horny, H-P., Prehm, P., Delpech, B., Krüger, W. H., Zander, A. R. & Schumacher, U., 2006, In: ACTA HISTOCHEM. 108, 2, p. 141-147 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of the intensity of the pretransplantation conditioning regimen in patients with prior invasive aspergillosis undergoing allogeneic hematopoietic stem cell transplantation: A retrospective survey of the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation.
Martino, R., Parody, R., Fukuda, T., Maertens, J., Theunissen, K., Ho, A., Mufti, G. J., Kröger, N., Zander, A. R., Heim, D., Paluszewska, M., Selleslag, D., Steinerova, K., Ljungman, P., Cesaro, S., Nihtinen, A., Cordonnier, C., Vazquez, L., López-Duarte, M., Lopez, J., Cabrera, R., Rovira, M., Neuburger, S., Cornely, O., Hunter, A. E., Marr, K. A., Dornbusch, H. J. & Einsele, H., 2006, In: BLOOD. 108, 9, p. 2928-2936 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Kinetics of plasma-cell chimerism after allogeneic stem cell transplantation by highly sensitive real-time PCR based on sequence polymorphism and its value to quantify minimal residual disease in patients with multiple myeloma.
Kröger, N., Zagrivnaja, M., Schwartz, S., Badbaran, A., Zabelina, T., Lioznov, M., Ayuketang Ayuk, F., Zander, A. R. & Fehse, B., 2006, In: EXP HEMATOL. 34, 5, p. 688-694 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low number of donor activating killer immunoglobulin-like receptors (KIR) genes but not KIR-ligand mismatch prevents relapse and improves disease-free survival in leukemia patients after in vivo T-cell depleted unrelated stem cell transplantation.
Kröger, N., Binder, T., Zabelina, T., Wolschke, C., Schieder, H., Renges, H., Ayuketang Ayuk, F., Dahlke, J., Eiermann, T. & Zander, A. R., 2006, In: TRANSPLANTATION. 82, 8, p. 1024-1030 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors.
Baum, C., Kustikova, O., Modlich, U., Li, Z. & Fehse, B., 2006, In: HUM GENE THER. 17, 3, p. 253-263 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neuropsychological function in high-risk breast cancer survivors after stem-cell supported high-dose therapy versus standard-dose chemotherapy: evaluation of long-term treatment effects.
Scherwath, A., Mehnert, A., Schleimer, B., Schirmer, L., Fehlauer, F., Kreienberg, R., Metzner, B., Thiel, E., Zander, A. R., Schulz-Kindermann, F. & Koch, U., 2006, In: ANN ONCOL. 17, 3, p. 415-423 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review