Department of Dermatology and Venereology
Publications
- 2018
Dynamics, ultrastructure and gene expression of human in-vitro organized testis cells from testicular sperm extraction biopsies
von Kopylow, K., Schulze, W., Salzbrunn, A., Schaks, M., Schäfer, E., Roth, B., Schlatt, S. & Spiess, A-N., 01.03.2018, In: MOL HUM REPROD. 24, 3, p. 123-134 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased Prevalence of Filaggrin Deficiency in 51 Patients with Recessive X-Linked Ichthyosis Presenting for Dermatological Examination
Süßmuth, K., Gruber, R., Rodriguez, E., Traupe, H., Amler, S., Sánchez-Guijo, A., Valentin, F., Tarinski, T., Straub, N., Metze, D., Schneider, S. W., Hausser, I., Baurecht, H., Weidinger, S. & Oji, V., 03.2018, In: J INVEST DERMATOL. 138, 3, p. 709-711 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Methylation profiling of human Spermatogonial Stem Cells (HSSCs) at single allele resolution
Fend, D., von Kopylow, K., Schulze, W., Salzbrunn, A., Spiess, A-N., El Hajj, N., Haaf, T., Zechner, U. & Linke, M., 19.02.2018, In: MED GENET-BERLIN. 30, 1, p. 135Research output: SCORING: Contribution to journal › Conference abstract in journal › Research
Parameter study of shipping conditions for the ready-to-use application of a 3D human hemicornea construct in drug absorption studies
Beißner, N., Zorn-Kruppa, M. & Reichl, S., 30.01.2018, In: INT J PHARMACEUT. 536, 1, p. 377-387 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Decreased Invasion of Urothelial Carcinoma of the Bladder by Inhibition of Matrix-Metalloproteinase 7
Bolenz, C., Knauf, D., John, A., Erben, P., Steidler, A., Schneider, S. W., Günes, C. & Gorzelanny, C., 20.01.2018, In: Bladder Cancer. 4, 1, p. 67-75 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bedside assessment of multiphoton tomography: From skin cell morphology via fluorescence lifetime imaging to clinical pathophysiology
Meß, C. & Huck, V., 2018, Multiphoton Microscopy and Fluorescence Lifetime Imaging: Applications in Biology and Medicine. König, K. (ed.). 1 ed. De Gruyter, p. 425-444 20 p. 22Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Das DNA-Methylierungsprofil humaner, aus TESE-Biopsien isolierter Spermatogonien auf Einzelzell- bzw. Einzel-Allel-Ebene
von Kopylow, K., Fend, D., Spiess, A-N., Schulze, W., Salzbrunn, A., Diederich, S., El Hajj, N., Haaf, T., Zechner, U. & Linke, M., 2018, In: J Reprodmed Endokrinol. 15, Supplementum 1, p. 2-3Research output: SCORING: Contribution to journal › Conference abstract in journal › Research
In-vitro-Reorganisation adulter humaner Hodenzellen in TESE-Biopsien im dreischichtigen 3D-Gradientensystem
von Kopylow, K., Schulze, W., Salzbrunn, A., Alves-Lopes, J. P., Stukenborg, J-B. & Spiess, A-N., 2018, In: J Reprodmed Endokrinol. 15, Supplementum 1, p. 3Research output: SCORING: Contribution to journal › Conference abstract in journal › Research
Knockdown of L1CAM significantly reduces metastasis in a xenograft model of human melanoma: L1CAM is a potential target for anti-melanoma therapy
Ernst, A-K., Putscher, A., Samatov, T. R., Suling, A., Galatenko, V. V., Shkurnikov, M. Y., Knyazev, E. N., Tonevitsky, A. G., Haalck, T., Lange, T., Maar, H., Schröder-Schwarz, J., Riecken, K., Schumacher, U. & Wicklein, D., 2018, In: PLOS ONE. 13, 2, p. e0192525Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Local NGF and GDNF levels modulate morphology and function of porcine DRG neurites, In Vitro
Klusch, A., Gorzelanny, C., Reeh, P. W., Schmelz, M., Petersen, M. & Sauer, S. K., 2018, In: PLOS ONE. 13, 9, p. e0203215Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Human spermatogonial markers
von Kopylow, K. & Spiess, A-N., 12.2017, In: STEM CELL RES. 25, p. 300-309 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Zelluläre Komposition, Ultrastruktur, Genexpression und Dynamik humaner in vitro-reorganisierter adulter Hodenzellen
von Kopylow, K., Schulze, W., Salzbrunn, A., Schaks, M., Schäfer, E., Schlatt, S., Roth, B. & Spiess, A-N., 12.2017, In: J Reprodmed Endokrinol. 14, 5, p. 233 - 234Research output: SCORING: Contribution to journal › Conference abstract in journal › Research
Margination and stretching of von Willebrand factor in the blood stream enable adhesion
Rack, K., Huck, V., Hoore, M., Fedosov, D. A., Schneider, S. W. & Gompper, G., 27.10.2017, In: SCI REP-UK. 7, 1, p. 14278Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy
Glodde, N., Bald, T., van den Boorn-Konijnenberg, D., Nakamura, K., O'Donnell, J. S., Szczepanski, S., Brandes, M., Eickhoff, S., Das, I., Shridhar, N., Hinze, D., Rogava, M., van der Sluis, T. C., Ruotsalainen, J. J., Gaffal, E., Landsberg, J., Ludwig, K. U., Wilhelm, C., Riek-Burchardt, M., Müller, A. J., Gebhardt, C., Scolyer, R. A., Long, G. V., Janzen, V., Teng, M. W. L., Kastenmüller, W., Mazzone, M., Smyth, M. J., Tüting, T. & Hölzel, M., 17.10.2017, In: IMMUNITY. 47, 4, p. 789-802.e9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair
Kumar, V., Fleming, T., Terjung, S., Gorzelanny, C., Gebhardt, C., Agrawal, R., Mall, M. A., Ranzinger, J., Zeier, M., Madhusudhan, T., Ranjan, S., Isermann, B., Liesz, A., Deshpande, D., Häring, H-U., Biswas, S. K., Reynolds, P. R., Hammes, H-P., Peperkok, R., Angel, P., Herzig, S. & Nawroth, P. P., 13.10.2017, In: NUCLEIC ACIDS RES. 45, 18, p. 10595-10613 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biphasic influence of Staphylococcus aureus on human epidermal tight junctions
Bäsler, K., Galliano, M-F., Bergmann, S., Rohde, H., Wladykowski, E., Vidal-Y-Sy, S., Guiraud, B., Houdek, P., Schüring, G., Volksdorf, T., Caruana, A., Bessou-Touya, S., Schneider, S. W., Duplan, H. & Brandner, J. M., 10.2017, In: ANN NY ACAD SCI. 1405, 1, p. 53-70Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Patient-Reported Outcome Measures in Pruritus: A Systematic Review of Measurement Properties
Schoch, D., Sommer, R., Augustin, M., Ständer, S. & Blome, C., 10.2017, In: J INVEST DERMATOL. 137, 10, p. 2069-2077Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Spontaneous lung metastasis formation of human Merkel cell carcinoma cell lines transplanted into scid mice
Knips, J., Czech-Sioli, M., Spohn, M., Heiland, M., Moll, I., Grundhoff, A., Schumacher, U. & Fischer, N., 01.07.2017, In: INT J CANCER. 141, 1, p. 160-171Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Current knowledge on biomarkers for contact sensitization and allergic contact dermatitis
Koppes, S. A., Engebretsen, K. A., Agner, T., Angelova-Fischer, I., Berents, T., Brandner, J., Brans, R., Clausen, M-L., Hummler, E., Jakasa, I., Jurakić-Tončic, R., John, S. M., Khnykin, D., Molin, S., Holm, J. O., Suomela, S., Thierse, H-J., Kezic, S., Martin, S. F. & Thyssen, J. P., 07.2017, In: CONTACT DERMATITIS. 77, 1, p. 1-16Research output: SCORING: Contribution to journal › SCORING: Review article › Research
T-cell diversification reflects antigen selection in the blood of patients on immune checkpoint inhibition and may be exploited as liquid biopsy biomarker
Akyüz, N., Brandt, A., Stein, A., Schliffke, S., Mährle, T., Quidde, J., Goekkurt, E., Loges, S., Haalck, T., Ford, C., Asemissen, A. M., Thiele, B., Radloff, J., Thenhausen, T., Krohn-Grimberghe, A., Bokemeyer, C. & Binder, M., 01.06.2017, In: INT J CANCER. 140, 11, p. 2535-2544Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epidermal equivalents of filaggrin null keratinocytes do not show impaired skin barrier function
Niehues, H., Schalkwijk, J., van Vlijmen-Willems, I. M. J. J., Rodijk-Olthuis, D., van Rossum, M. M., Wladykowski, E., Brandner, J. M., van den Bogaard, E. H. J. & Zeeuwen, P. L. J. M., 06.2017, In: J ALLERGY CLIN IMMUN. 139, 6, p. 1979-1981Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Tight Junction Proteins Claudin-1 and Occludin Are Important for Cutaneous Wound Healing
Volksdorf, T., Heilmann, J., Eming, S. A., Schawjinski, K., Zorn-Kruppa, M., Ueck, C., Vidal-Y-Sy, S., Windhorst, S., Jücker, M., Moll, I. & Brandner, J. M., 06.2017, In: AM J PATHOL. 187, 6, p. 1301-1312Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response
Bernhardt, M., Novak, D., Assenov, Y., Orouji, E., Knappe, N., Weina, K., Reith, M., Larribere, L., Gebhardt, C., Plass, C., Umansky, V. & Utikal, J., 09.05.2017, In: STEM CELL REP. 8, 5, p. 1379-1391 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Klinische Merkmale und Versorgung von Hautkrebs. Gezielte Behandlung
Augustin, M. & Schneider, S. W., 05.2017, In: Ärzteblatt MV. 27, 5, p. 165-171Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Matrix meets Inflammation and DNA Repair: Meeting Report of the 3(rd) ADF Round Table
Brandner, J. M., Emmert, S., Wolk, K. & Ludwig, R. J., 05.2017, In: EXP DERMATOL. 26, 5, p. 464-466Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Sentinel node metastasis mitotic rate (SN-MMR) as a prognostic indicator of rapidly progressing disease in patients with sentinel node-positive melanomas
Baum, C., Weiss, C., Gebhardt, C., Utikal, J., Marx, A., Koenen, W. & Géraud, C., 15.04.2017, In: INT J CANCER. 140, 8, p. 1907-1917 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Myeloid-derived suppressor cells and tumor escape from immune surveillance
Umansky, V., Blattner, C., Fleming, V., Hu, X., Gebhardt, C., Altevogt, P. & Utikal, J., 04.2017, In: SEMIN IMMUNOPATHOL. 39, 3, p. 295-305 11 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
D-dimers in malignant melanoma: Association with prognosis and dynamic variation in disease progress
Desch, A., Gebhardt, C., Utikal, J. & Schneider, S. W., 15.02.2017, In: INT J CANCER. 140, 4, p. 914-921 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tight junctions in skin inflammation
Bäsler, K. & Brandner, J. M., 01.2017, In: PFLUG ARCH EUR J PHY. 469, 1, p. 3-14 12 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Comparison of In-Vitro and Ex-Vivo Wound Healing Assays for the Investigation of Diabetic Wound Healing and Demonstration of a Beneficial Effect of a Triterpene Extract
Ueck, C., Volksdorf, T., Houdek, P., Vidal-Y-Sy, S., Sehner, S., Ellinger, B., Lobmann, R., Larena-Avellaneda, A., Reinshagen, K., Ridderbusch, I., Kohrmeyer, K., Moll, I., Daniels, R., Werner, P., Merfort, I. & Brandner, J. M., 2017, In: PLOS ONE. 12, 1, p. e0169028Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
From morphology to clinical pathophysiology: multiphoton fluorescence lifetime imaging at patients' bedside
Meß, C., Zens, K., Gorzelanny, C., Metze, D., Luger, T. A., König, K., Schneider, S. & Huck, V., 2017, In: Proc. SPIE. 10069, p. 100691E-100691EResearch output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In vitro eye irritation testing using the open source reconstructed hemicornea - a ring trial
Mewes, K. R., Engelke, M., Zorn-Kruppa, M., Bartok, M., Tandon, R., Brandner, J. M. & Petersohn, D., 2017, In: ALTEX-ALTERN ANIM EX. 34, 3, p. 430-434Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Klinische Merkmale und Versorgung von Hautkrebs. Gezielte Behandlung
Augustin, M. & Schneider, S., 2017, In: Hamb Ärztebl. 71, 3, p. 12-16Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nanoencapsulated capsaicin changes migration behavior and morphology of madin darby canine kidney cell monolayers
Kaiser, M., Pohl, L., Ketelhut, S., Kastl, L., Gorzelanny, C., Götte, M., Schnekenburger, J., Goycoolea, F. M. & Kemper, B., 2017, In: PLOS ONE. 12, 11, p. e0187497Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rezidivierende Abszesse - oder doch mehr?
Kirsten, N., Schneider, S. & Augustin, M., 2017, In: Hamb Ärztebl. 71, 10, p. 30-31Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Role of mutational status of GNAQ and GNA11 in the diagnosis of melanocytic tumors: Response
Griewank, K. G., Koelsche, C., Wenz, F., Giordano, F. A. & Gebhardt, C., 2017, In: J NEUROSURG.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of the Coagulation System in Genitourinary Cancers: Review
John, A., Gorzelanny, C., Bauer, A. T., Schneider, S. W. & Bolenz, C., 2017, In: CLIN GENITOURIN CANC.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2016
System-specific periodicity in quantitative real-time polymerase chain reaction data questions threshold-based quantitation.
Spiess, A-N., Rödiger, S., Burdukiewicz, M., Volksdorf, T. & Tellinghuisen, J., 13.12.2016, In: SCI REP-UK. 6, p. 38951Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries
Damsgaard, J., Joensen, U. N., Carlsen, E., Erenpreiss, J., Blomberg Jensen, M., Matulevicius, V., Zilaitiene, B., Olesen, I. A., Perheentupa, A., Punab, M., Salzbrunn, A., Toppari, J., Virtanen, H. E., Juul, A., Skakkebæk, N. E. & Jørgensen, N., 12.2016, In: EUR UROL. 70, 6, p. 1019-1029 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The role of tight junctions in skin barrier function and dermal absorption
Bäsler, K., Bergmann, S., Heisig, M., Naegel, A., Zorn-Kruppa, M. & Brandner, J. M., 28.11.2016, In: J CONTROL RELEASE. 242, p. 105-118Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Baseline Biomarkers for Outcome of Melanoma Patients Treated with Pembrolizumab
Weide, B., Martens, A., Hassel, J. C., Berking, C., Postow, M. A., Bisschop, K., Simeone, E., Mangana, J., Schilling, B., Di Giacomo, A. M., Brenner, N., Kähler, K., Heinzerling, L., Gutzmer, R., Bender, A., Gebhardt, C., Romano, E., Meier, F., Martus, P., Maio, M., Blank, C., Schadendorf, D., Dummer, R., Ascierto, P. A., Hospers, G., Garbe, C. & Wolchok, J. D., 15.11.2016, In: CLIN CANCER RES. 22, 22, p. 5487-5496 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Role of Myeloid-Derived Suppressor Cells (MDSC) in Cancer Progression
Umansky, V., Blattner, C., Gebhardt, C. & Utikal, J., 03.11.2016, In: VACCINES-BASEL. 4, 4Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Preferences of German melanoma patients for interferon (IFN) α-2b toxicities (the DeCOG "GERMELATOX survey") versus melanoma recurrence to quantify patients' relative values for adjuvant therapy
Kaehler, K. C., Blome, C., Forschner, A., Gutzmer, R., Haalck, T., Heinzerling, L., Kornek, T., Livingstone, E., Loquai, C., Maul, L. V., Lang, B. M., Schadendorf, D., Stade, B., Terheyden, P., Utikal, J., Wagner, T., Hauschild, A., Garbe, C. & Augustin, M., 11.2016, In: MEDICINE. 95, 46, p. e5375Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Heparins that block VEGF-A-mediated von Willebrand factor fiber generation are potent inhibitors of hematogenous but not lymphatic metastasis
Goertz, L., Schneider, S. W., Desch, A., Mayer, F. T., Koett, J., Nowak, K., Karampinis, I., Bohlmann, M. K., Umansky, V. & Bauer, A. T., 18.10.2016, In: ONCOTARGET. 7, 42, p. 68527-68545 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo
Wegwitz, F., Lenfert, E., Gerstel, D., von Ehrenstein, L., Einhoff, J., Schmidt, G., Logsdon, M., Brandner, J., Tiegs, G., Beauchemin, N., Wagener, C., Deppert, W. & Horst, A. K., 27.09.2016, In: ONCOTARGET. 7, 39, p. 63730-63746Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reorganisation testikulärer Strukturen bei In-vitro-kultivierten Zellen aus dem humanen adulten normogonadotropen Hoden mit vollständiger Spermatogenese
von Kopylow, K., Schlatt, S., Schulze, W., Salzbrunn, A. & Spiess, A-N., 08.09.2016, In: J Reprodmed Endokrinol. 13, 4, p. 151Research output: SCORING: Contribution to journal › Conference abstract in journal › Research
The impact of sperm protamine deficiency and sperm DNA damage on human male fertility: a systematic review and meta-analysis
Ni, K., Spiess, A-N., Schuppe, H-C. & Steger, K., 09.2016, In: ANDROLOGY-US. 4, 5, p. 789-99 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comment on "Absence of sperm RNA elements correlates with idiopathic male infertility"
Cappallo-Obermann, H. & Spiess, A-N., 24.08.2016, In: SCI TRANSL MED. 8, 353, p. 353tc1Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Adjuvant treatment with pegylated interferon α-2a versus low-dose interferon α-2a in patients with high-risk melanoma: a randomized phase III DeCOG trial
Eigentler, T. K., Gutzmer, R., Hauschild, A., Heinzerling, L., Schadendorf, D., Nashan, D., Hölzle, E., Kiecker, F., Becker, J., Sunderkötter, C., Moll, I., Richtig, E., Pönitzsch, I., Pehamberger, H., Kaufmann, R., Pföhler, C., Vogt, T., Berking, C., Praxmarer, M., Garbe, C. & Dermatologic Cooperative Oncology Group (DeCOG), 08.2016, In: ANN ONCOL. 27, 8, p. 1625-32 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages
Huber, R., Meier, B., Otsuka, A., Fenini, G., Satoh, T., Gehrke, S., Widmer, D., Levesque, M. P., Mangana, J., Kerl, K., Gebhardt, C., Fujii, H., Nakashima, C., Nonomura, Y., Kabashima, K., Dummer, R., Contassot, E. & French, L. E., 18.07.2016, In: SCI REP-UK. 6, p. 29914Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review