Department of Dermatology and Venereology

Publications

  1. 2018
  2. Dynamics, ultrastructure and gene expression of human in-vitro organized testis cells from testicular sperm extraction biopsies

    von Kopylow, K., Schulze, W., Salzbrunn, A., Schaks, M., Schäfer, E., Roth, B., Schlatt, S. & Spiess, A-N., 01.03.2018, In: MOL HUM REPROD. 24, 3, p. 123-134 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Increased Prevalence of Filaggrin Deficiency in 51 Patients with Recessive X-Linked Ichthyosis Presenting for Dermatological Examination

    Süßmuth, K., Gruber, R., Rodriguez, E., Traupe, H., Amler, S., Sánchez-Guijo, A., Valentin, F., Tarinski, T., Straub, N., Metze, D., Schneider, S. W., Hausser, I., Baurecht, H., Weidinger, S. & Oji, V., 03.2018, In: J INVEST DERMATOL. 138, 3, p. 709-711 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  4. Methylation profiling of human Spermatogonial Stem Cells (HSSCs) at single allele resolution

    Fend, D., von Kopylow, K., Schulze, W., Salzbrunn, A., Spiess, A-N., El Hajj, N., Haaf, T., Zechner, U. & Linke, M., 19.02.2018, In: MED GENET-BERLIN. 30, 1, p. 135

    Research output: SCORING: Contribution to journalConference abstract in journalResearch

  5. Parameter study of shipping conditions for the ready-to-use application of a 3D human hemicornea construct in drug absorption studies

    Beißner, N., Zorn-Kruppa, M. & Reichl, S., 30.01.2018, In: INT J PHARMACEUT. 536, 1, p. 377-387 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Decreased Invasion of Urothelial Carcinoma of the Bladder by Inhibition of Matrix-Metalloproteinase 7

    Bolenz, C., Knauf, D., John, A., Erben, P., Steidler, A., Schneider, S. W., Günes, C. & Gorzelanny, C., 20.01.2018, In: Bladder Cancer. 4, 1, p. 67-75 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Bedside assessment of multiphoton tomography: From skin cell morphology via fluorescence lifetime imaging to clinical pathophysiology

    Meß, C. & Huck, V., 2018, Multiphoton Microscopy and Fluorescence Lifetime Imaging: Applications in Biology and Medicine. König, K. (ed.). 1 ed. De Gruyter, p. 425-444 20 p. 22

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  8. Das DNA-Methylierungsprofil humaner, aus TESE-Biopsien isolierter Spermatogonien auf Einzelzell- bzw. Einzel-Allel-Ebene

    von Kopylow, K., Fend, D., Spiess, A-N., Schulze, W., Salzbrunn, A., Diederich, S., El Hajj, N., Haaf, T., Zechner, U. & Linke, M., 2018, In: J Reprodmed Endokrinol. 15, Supplementum 1, p. 2-3

    Research output: SCORING: Contribution to journalConference abstract in journalResearch

  9. In-vitro-Reorganisation adulter humaner Hodenzellen in TESE-Biopsien im dreischichtigen 3D-Gradientensystem

    von Kopylow, K., Schulze, W., Salzbrunn, A., Alves-Lopes, J. P., Stukenborg, J-B. & Spiess, A-N., 2018, In: J Reprodmed Endokrinol. 15, Supplementum 1, p. 3

    Research output: SCORING: Contribution to journalConference abstract in journalResearch

  10. Knockdown of L1CAM significantly reduces metastasis in a xenograft model of human melanoma: L1CAM is a potential target for anti-melanoma therapy

    Ernst, A-K., Putscher, A., Samatov, T. R., Suling, A., Galatenko, V. V., Shkurnikov, M. Y., Knyazev, E. N., Tonevitsky, A. G., Haalck, T., Lange, T., Maar, H., Schröder-Schwarz, J., Riecken, K., Schumacher, U. & Wicklein, D., 2018, In: PLOS ONE. 13, 2, p. e0192525

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Local NGF and GDNF levels modulate morphology and function of porcine DRG neurites, In Vitro

    Klusch, A., Gorzelanny, C., Reeh, P. W., Schmelz, M., Petersen, M. & Sauer, S. K., 2018, In: PLOS ONE. 13, 9, p. e0203215

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. 2017
  13. Human spermatogonial markers

    von Kopylow, K. & Spiess, A-N., 12.2017, In: STEM CELL RES. 25, p. 300-309 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Zelluläre Komposition, Ultrastruktur, Genexpression und Dynamik humaner in vitro-reorganisierter adulter Hodenzellen

    von Kopylow, K., Schulze, W., Salzbrunn, A., Schaks, M., Schäfer, E., Schlatt, S., Roth, B. & Spiess, A-N., 12.2017, In: J Reprodmed Endokrinol. 14, 5, p. 233 - 234

    Research output: SCORING: Contribution to journalConference abstract in journalResearch

  15. Margination and stretching of von Willebrand factor in the blood stream enable adhesion

    Rack, K., Huck, V., Hoore, M., Fedosov, D. A., Schneider, S. W. & Gompper, G., 27.10.2017, In: SCI REP-UK. 7, 1, p. 14278

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy

    Glodde, N., Bald, T., van den Boorn-Konijnenberg, D., Nakamura, K., O'Donnell, J. S., Szczepanski, S., Brandes, M., Eickhoff, S., Das, I., Shridhar, N., Hinze, D., Rogava, M., van der Sluis, T. C., Ruotsalainen, J. J., Gaffal, E., Landsberg, J., Ludwig, K. U., Wilhelm, C., Riek-Burchardt, M., Müller, A. J., Gebhardt, C., Scolyer, R. A., Long, G. V., Janzen, V., Teng, M. W. L., Kastenmüller, W., Mazzone, M., Smyth, M. J., Tüting, T. & Hölzel, M., 17.10.2017, In: IMMUNITY. 47, 4, p. 789-802.e9

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair

    Kumar, V., Fleming, T., Terjung, S., Gorzelanny, C., Gebhardt, C., Agrawal, R., Mall, M. A., Ranzinger, J., Zeier, M., Madhusudhan, T., Ranjan, S., Isermann, B., Liesz, A., Deshpande, D., Häring, H-U., Biswas, S. K., Reynolds, P. R., Hammes, H-P., Peperkok, R., Angel, P., Herzig, S. & Nawroth, P. P., 13.10.2017, In: NUCLEIC ACIDS RES. 45, 18, p. 10595-10613 19 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Biphasic influence of Staphylococcus aureus on human epidermal tight junctions

    Bäsler, K., Galliano, M-F., Bergmann, S., Rohde, H., Wladykowski, E., Vidal-Y-Sy, S., Guiraud, B., Houdek, P., Schüring, G., Volksdorf, T., Caruana, A., Bessou-Touya, S., Schneider, S. W., Duplan, H. & Brandner, J. M., 10.2017, In: ANN NY ACAD SCI. 1405, 1, p. 53-70

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Patient-Reported Outcome Measures in Pruritus: A Systematic Review of Measurement Properties

    Schoch, D., Sommer, R., Augustin, M., Ständer, S. & Blome, C., 10.2017, In: J INVEST DERMATOL. 137, 10, p. 2069-2077

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  20. Spontaneous lung metastasis formation of human Merkel cell carcinoma cell lines transplanted into scid mice

    Knips, J., Czech-Sioli, M., Spohn, M., Heiland, M., Moll, I., Grundhoff, A., Schumacher, U. & Fischer, N., 01.07.2017, In: INT J CANCER. 141, 1, p. 160-171

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Current knowledge on biomarkers for contact sensitization and allergic contact dermatitis

    Koppes, S. A., Engebretsen, K. A., Agner, T., Angelova-Fischer, I., Berents, T., Brandner, J., Brans, R., Clausen, M-L., Hummler, E., Jakasa, I., Jurakić-Tončic, R., John, S. M., Khnykin, D., Molin, S., Holm, J. O., Suomela, S., Thierse, H-J., Kezic, S., Martin, S. F. & Thyssen, J. P., 07.2017, In: CONTACT DERMATITIS. 77, 1, p. 1-16

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  22. T-cell diversification reflects antigen selection in the blood of patients on immune checkpoint inhibition and may be exploited as liquid biopsy biomarker

    Akyüz, N., Brandt, A., Stein, A., Schliffke, S., Mährle, T., Quidde, J., Goekkurt, E., Loges, S., Haalck, T., Ford, C., Asemissen, A. M., Thiele, B., Radloff, J., Thenhausen, T., Krohn-Grimberghe, A., Bokemeyer, C. & Binder, M., 01.06.2017, In: INT J CANCER. 140, 11, p. 2535-2544

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Epidermal equivalents of filaggrin null keratinocytes do not show impaired skin barrier function

    Niehues, H., Schalkwijk, J., van Vlijmen-Willems, I. M. J. J., Rodijk-Olthuis, D., van Rossum, M. M., Wladykowski, E., Brandner, J. M., van den Bogaard, E. H. J. & Zeeuwen, P. L. J. M., 06.2017, In: J ALLERGY CLIN IMMUN. 139, 6, p. 1979-1981

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  24. Tight Junction Proteins Claudin-1 and Occludin Are Important for Cutaneous Wound Healing

    Volksdorf, T., Heilmann, J., Eming, S. A., Schawjinski, K., Zorn-Kruppa, M., Ueck, C., Vidal-Y-Sy, S., Windhorst, S., Jücker, M., Moll, I. & Brandner, J. M., 06.2017, In: AM J PATHOL. 187, 6, p. 1301-1312

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response

    Bernhardt, M., Novak, D., Assenov, Y., Orouji, E., Knappe, N., Weina, K., Reith, M., Larribere, L., Gebhardt, C., Plass, C., Umansky, V. & Utikal, J., 09.05.2017, In: STEM CELL REP. 8, 5, p. 1379-1391 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Klinische Merkmale und Versorgung von Hautkrebs. Gezielte Behandlung

    Augustin, M. & Schneider, S. W., 05.2017, In: Ärzteblatt MV. 27, 5, p. 165-171

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Matrix meets Inflammation and DNA Repair: Meeting Report of the 3(rd) ADF Round Table

    Brandner, J. M., Emmert, S., Wolk, K. & Ludwig, R. J., 05.2017, In: EXP DERMATOL. 26, 5, p. 464-466

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  28. Sentinel node metastasis mitotic rate (SN-MMR) as a prognostic indicator of rapidly progressing disease in patients with sentinel node-positive melanomas

    Baum, C., Weiss, C., Gebhardt, C., Utikal, J., Marx, A., Koenen, W. & Géraud, C., 15.04.2017, In: INT J CANCER. 140, 8, p. 1907-1917 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Myeloid-derived suppressor cells and tumor escape from immune surveillance

    Umansky, V., Blattner, C., Fleming, V., Hu, X., Gebhardt, C., Altevogt, P. & Utikal, J., 04.2017, In: SEMIN IMMUNOPATHOL. 39, 3, p. 295-305 11 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  30. D-dimers in malignant melanoma: Association with prognosis and dynamic variation in disease progress

    Desch, A., Gebhardt, C., Utikal, J. & Schneider, S. W., 15.02.2017, In: INT J CANCER. 140, 4, p. 914-921 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Tight junctions in skin inflammation

    Bäsler, K. & Brandner, J. M., 01.2017, In: PFLUG ARCH EUR J PHY. 469, 1, p. 3-14 12 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  32. Comparison of In-Vitro and Ex-Vivo Wound Healing Assays for the Investigation of Diabetic Wound Healing and Demonstration of a Beneficial Effect of a Triterpene Extract

    Ueck, C., Volksdorf, T., Houdek, P., Vidal-Y-Sy, S., Sehner, S., Ellinger, B., Lobmann, R., Larena-Avellaneda, A., Reinshagen, K., Ridderbusch, I., Kohrmeyer, K., Moll, I., Daniels, R., Werner, P., Merfort, I. & Brandner, J. M., 2017, In: PLOS ONE. 12, 1, p. e0169028

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. From morphology to clinical pathophysiology: multiphoton fluorescence lifetime imaging at patients' bedside

    Meß, C., Zens, K., Gorzelanny, C., Metze, D., Luger, T. A., König, K., Schneider, S. & Huck, V., 2017, In: Proc. SPIE. 10069, p. 100691E-100691E

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. In vitro eye irritation testing using the open source reconstructed hemicornea - a ring trial

    Mewes, K. R., Engelke, M., Zorn-Kruppa, M., Bartok, M., Tandon, R., Brandner, J. M. & Petersohn, D., 2017, In: ALTEX-ALTERN ANIM EX. 34, 3, p. 430-434

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Klinische Merkmale und Versorgung von Hautkrebs. Gezielte Behandlung

    Augustin, M. & Schneider, S., 2017, In: Hamb Ärztebl. 71, 3, p. 12-16

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Nanoencapsulated capsaicin changes migration behavior and morphology of madin darby canine kidney cell monolayers

    Kaiser, M., Pohl, L., Ketelhut, S., Kastl, L., Gorzelanny, C., Götte, M., Schnekenburger, J., Goycoolea, F. M. & Kemper, B., 2017, In: PLOS ONE. 12, 11, p. e0187497

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Rezidivierende Abszesse - oder doch mehr?

    Kirsten, N., Schneider, S. & Augustin, M., 2017, In: Hamb Ärztebl. 71, 10, p. 30-31

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  38. Role of mutational status of GNAQ and GNA11 in the diagnosis of melanocytic tumors: Response

    Griewank, K. G., Koelsche, C., Wenz, F., Giordano, F. A. & Gebhardt, C., 2017, In: J NEUROSURG.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Role of the Coagulation System in Genitourinary Cancers: Review

    John, A., Gorzelanny, C., Bauer, A. T., Schneider, S. W. & Bolenz, C., 2017, In: CLIN GENITOURIN CANC.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  40. 2016
  41. System-specific periodicity in quantitative real-time polymerase chain reaction data questions threshold-based quantitation.

    Spiess, A-N., Rödiger, S., Burdukiewicz, M., Volksdorf, T. & Tellinghuisen, J., 13.12.2016, In: SCI REP-UK. 6, p. 38951

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries

    Damsgaard, J., Joensen, U. N., Carlsen, E., Erenpreiss, J., Blomberg Jensen, M., Matulevicius, V., Zilaitiene, B., Olesen, I. A., Perheentupa, A., Punab, M., Salzbrunn, A., Toppari, J., Virtanen, H. E., Juul, A., Skakkebæk, N. E. & Jørgensen, N., 12.2016, In: EUR UROL. 70, 6, p. 1019-1029 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. The role of tight junctions in skin barrier function and dermal absorption

    Bäsler, K., Bergmann, S., Heisig, M., Naegel, A., Zorn-Kruppa, M. & Brandner, J. M., 28.11.2016, In: J CONTROL RELEASE. 242, p. 105-118

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Baseline Biomarkers for Outcome of Melanoma Patients Treated with Pembrolizumab

    Weide, B., Martens, A., Hassel, J. C., Berking, C., Postow, M. A., Bisschop, K., Simeone, E., Mangana, J., Schilling, B., Di Giacomo, A. M., Brenner, N., Kähler, K., Heinzerling, L., Gutzmer, R., Bender, A., Gebhardt, C., Romano, E., Meier, F., Martus, P., Maio, M., Blank, C., Schadendorf, D., Dummer, R., Ascierto, P. A., Hospers, G., Garbe, C. & Wolchok, J. D., 15.11.2016, In: CLIN CANCER RES. 22, 22, p. 5487-5496 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. The Role of Myeloid-Derived Suppressor Cells (MDSC) in Cancer Progression

    Umansky, V., Blattner, C., Gebhardt, C. & Utikal, J., 03.11.2016, In: VACCINES-BASEL. 4, 4

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  46. Preferences of German melanoma patients for interferon (IFN) α-2b toxicities (the DeCOG "GERMELATOX survey") versus melanoma recurrence to quantify patients' relative values for adjuvant therapy

    Kaehler, K. C., Blome, C., Forschner, A., Gutzmer, R., Haalck, T., Heinzerling, L., Kornek, T., Livingstone, E., Loquai, C., Maul, L. V., Lang, B. M., Schadendorf, D., Stade, B., Terheyden, P., Utikal, J., Wagner, T., Hauschild, A., Garbe, C. & Augustin, M., 11.2016, In: MEDICINE. 95, 46, p. e5375

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Heparins that block VEGF-A-mediated von Willebrand factor fiber generation are potent inhibitors of hematogenous but not lymphatic metastasis

    Goertz, L., Schneider, S. W., Desch, A., Mayer, F. T., Koett, J., Nowak, K., Karampinis, I., Bohlmann, M. K., Umansky, V. & Bauer, A. T., 18.10.2016, In: ONCOTARGET. 7, 42, p. 68527-68545 19 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo

    Wegwitz, F., Lenfert, E., Gerstel, D., von Ehrenstein, L., Einhoff, J., Schmidt, G., Logsdon, M., Brandner, J., Tiegs, G., Beauchemin, N., Wagener, C., Deppert, W. & Horst, A. K., 27.09.2016, In: ONCOTARGET. 7, 39, p. 63730-63746

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Reorganisation testikulärer Strukturen bei In-vitro-kultivierten Zellen aus dem humanen adulten normogonadotropen Hoden mit vollständiger Spermatogenese

    von Kopylow, K., Schlatt, S., Schulze, W., Salzbrunn, A. & Spiess, A-N., 08.09.2016, In: J Reprodmed Endokrinol. 13, 4, p. 151

    Research output: SCORING: Contribution to journalConference abstract in journalResearch

  50. The impact of sperm protamine deficiency and sperm DNA damage on human male fertility: a systematic review and meta-analysis

    Ni, K., Spiess, A-N., Schuppe, H-C. & Steger, K., 09.2016, In: ANDROLOGY-US. 4, 5, p. 789-99 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Comment on "Absence of sperm RNA elements correlates with idiopathic male infertility"

    Cappallo-Obermann, H. & Spiess, A-N., 24.08.2016, In: SCI TRANSL MED. 8, 353, p. 353tc1

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  52. Adjuvant treatment with pegylated interferon α-2a versus low-dose interferon α-2a in patients with high-risk melanoma: a randomized phase III DeCOG trial

    Eigentler, T. K., Gutzmer, R., Hauschild, A., Heinzerling, L., Schadendorf, D., Nashan, D., Hölzle, E., Kiecker, F., Becker, J., Sunderkötter, C., Moll, I., Richtig, E., Pönitzsch, I., Pehamberger, H., Kaufmann, R., Pföhler, C., Vogt, T., Berking, C., Praxmarer, M., Garbe, C. & Dermatologic Cooperative Oncology Group (DeCOG), 08.2016, In: ANN ONCOL. 27, 8, p. 1625-32 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages

    Huber, R., Meier, B., Otsuka, A., Fenini, G., Satoh, T., Gehrke, S., Widmer, D., Levesque, M. P., Mangana, J., Kerl, K., Gebhardt, C., Fujii, H., Nakashima, C., Nonomura, Y., Kabashima, K., Dummer, R., Contassot, E. & French, L. E., 18.07.2016, In: SCI REP-UK. 6, p. 29914

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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