Institute of Pathology
Publications
- 2012
Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation.
Börno, S. T., Fischer, A., Kerick, M., Fälth, M., Laible, M., Brase, J. C., Kuner, R., Dahl, A., Grimm, C., Sayanjali, B., Isau, M., Röhr, C., Wunderlich, A., Timmermann, B., Claus, R., Plass, C., Graefen, M., Simon, R., Demichelis, F., Rubin, M. A., Sauter, G., Schlomm, T., Sültmann, H., Lehrach, H. & Schweiger, M. R., 2012, In: CANCER DISCOV. 2, 11, p. 1024-1035 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genomic deletion of PTEN is associated with tumor progression and early PSA recurrence in ERG fusion-positive and fusion-negative prostate cancer.
Krohn, A., Diedler, T., Burkhardt, L., Mayer, P. S., Colin, D. S., Meyer-Kornblum, M., Kötschau, D., Tennstedt, P., Huang, J., Gerhäuser, C., Mader, M., Kurtz, S., Sirma, H., Saad, F., Steuber, T., Graefen, M., Plass, C., Sauter, G., Simon, R., Minner, S. J. P. & Schlomm, T., 2012, In: AM J PATHOL. 181, 2, p. 401-412 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Heterogeneity of ERBB2 amplification in adenocarcinoma, squamous cell carcinoma and large cell undifferentiated carcinoma of the lung.
Grob, T., Kannengiesser, I., Tsourlakis, M. C., Atanackovic, D., König, A., Vashist, Y., Klose, H., Marx, A. H., Koops, S., Simon, R., Izbicki, J. R., Bokemeyer, C., Sauter, G. & Wilczak, W., 2012, In: MODERN PATHOL. 25, 12, p. 1566-1573 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HPV status in patients with head and neck of carcinoma of unknown primary site: HPV, tobacco smoking, and outcome.
Tribius, S., Hoffmann, A. S., Bastrop, S., Görögh, T., Haag, J., Röcken, C., Clauditz, T., Grob, T., Wilczak, W., Tennstedt, P., Borcherding, A., Petersen, C. & Hoffmann, M., 2012, In: ORAL ONCOL. 48, 11, p. 1178-1184 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human prostate cancer in a clinically relevant xenograft mouse model: identification of β(1,6)-branched oligosaccharides as a marker of tumor progression.
Lange, T., Ullrich, S., Müller, I., Nentwich, M., Stübke, K., Feldhaus, S., Knies, C., Hellwinkel, O., Vessella, R. L., Abramjuk, C., Anders, M., Schröder-Schwarz, J., Schlomm, T., Huland, H., Sauter, G. & Schumacher, U., 2012, In: CLIN CANCER RES. 18, 5, p. 1364-1373 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immature renal dendritic cells recruit regulatory CXCR6(+) invariant natural killer T cells to attenuate crescentic GN.
Riedel, J-H., Paust, H-J., Turner, J. E., Tittel, A. P., Krebs, C., Disteldorf, E., Wegscheid, C., Tiegs, G., Velden, J., Mittrücker, H. W., Garbi, N., Stahl, R. A. K., Steinmetz, O., Kurts, C. & Panzer, U., 2012, In: J AM SOC NEPHROL. 23, 12, p. 1987-2000 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunoexpression analysis and prognostic value of BLCAP in breast cancer.
Gromova, I., Gromov, P., Kroman, N., Wielenga, V. T., Simon, R., Sauter, G. & Moreira, J. M. A., 2012, In: PLOS ONE. 7, 9, p. 45967 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Induction of heme oxygenase 1 by HMG-CoA-Reductase inhibitors interferes with HCV replication
Loscher, C., Wüstenberg, A., Keller, A., Lehmann, E., Sirma, H., Bartenschlager, R., Lohmann, V., Dandri-Petersen, M., Tiegs, G. & Sass, G., 2012, Zeitschrift für Gastroenterologie.Research output: SCORING: Contribution to book/anthology › Conference contribution - Poster › Transfer
Kreatininanstieg bei einem 85-jährigen Patienten mit INR-Entgleisung
von Lewinski, M., Helmchen, U. & Wenzel, U., 2012, In: NEPHROLOGE. 7, 2, p. 155-159 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
L1 is highly expressed in tumors of the nervous system: a study of over 8000 human tissues.
Rawnaq, T., Quaas, A., Zander, H., Gros, S., Reichelt, U., Blessmann, M., Wilczak, W., Schachner, M., Sauter, G., Izbicki, J. R. & Kaifi, J., 2012, In: J SURG RES. 173, 2, p. 314-319 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Losses at chromosome 4q are associated with poor survival in operable ductal pancreatic adenocarcinoma.
Lübke, A., Baudis, M., Matthaei, H., Vashist, Y., Verde, P. E., Hosch, S. B., Erbersdobler, A., Klein, C. A., Izbicki, J. R., Knoefel, W-T. & Stoecklein, N. H., 2012, In: PANCREATOLOGY. 12, 1, p. 16-22 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Loss of protein expression and recurrent DNA hypermethylation of the GNG7 gene in squamous cell carcinoma of the head and neck.
Hartmann, S., Szaumkessel, M., Salaverria, I., Simon, R., Sauter, G., Kiwerska, K., Gawecki, W., Bodnar, M., Marszalek, A., Richter, J., Brauze, D., Zemke, N., Jarmuz, M., Hansmann, M-L., Siebert, R., Szyfter, K. & Giefing, M., 2012, In: J APPL GENET. 53, 2, p. 167-174 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mammographic density and inter-observer variability of pathologic evaluation of core biopsies among women with mammographic abnormalities.
Trocchi, P., Ursin, G., Kuss, O., Ruschke, K., Schmidt-Pokrzywniak, A., Holzhausen, H-J., Löning, T., Thomssen, C., Böcker, W., Kluttig, A. & Stang, A., 2012, In: BMC CANCER. 12, p. 554Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MED12 mutations in uterine fibroids--their relationship to cytogenetic subgroups.
Markowski, D. N., Bartnitzke, S., Löning, T., Drieschner, N., Helmke, B. M. & Bullerdiek, J., 2012, In: INT J CANCER. 131, 7, p. 1528-1536 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MicroRNAs miR-371-3 in serum as diagnostic tools in the management of testicular germ cell tumours.
Dieckmann, K-P., Spiekermann, M., Balks, T., Flor, I., Löning, T., Bullerdiek, J. & Belge, G., 2012, In: BRIT J CANCER. 107, 10, p. 1754-1760 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Moderne Leichenschau
Heinemann, A., Seifert, D., Denzer, U. W., Rösch, T., Lorenzen, M., Adam, G., Wichmann, D., Kluge, S., Vogel, H., Sauter, G. & Püschel, K., 2012, In: Hamb Ärztebl. 66, 06/07, p. 12-17 06/07.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Morphological study of synovial changes in two-stage reconstructions of the infected hip and knee arthroplasties.
Gontarewicz, A., Niggemeyer, O., Tharun, L., Grancicova, L., Rüther, W. & Zustin, J., 2012, In: BMJ OPEN. 2, 4, p. 1467 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nasolabial cyst: case report with respect to immunohistochemical findings.
Friedrich, R., Scheuer, H., Assaf, A. & Zustin, J., 2012, In: IN VIVO. 26, 3, p. 453-458 6 p., 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neurovascular structure-adjacent frozen-section examination (NeuroSAFE) increases nerve-sparing frequency and reduces positive surgical margins in open and robot-assisted laparoscopic radical prostatectomy: experience after 11,069 consecutive patients.
Schlomm, T., Tennstedt, P., Huxhold, C., Steuber, T., Salomon, G., Michl, U., Heinzer, H., Hansen, J., Budäus, L., Steurer, S., Wittmer, C., Minner, S. J. P., Haese, A., Sauter, G., Graefen, M. & Huland, H., 2012, In: EUR UROL. 62, 2, p. 333-340 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Gelderblom, M., Weymar, A., Bernreuther, C., Velden, J., Arunachalam, P., Steinbach, K., Orthey, E., Arumugam, T. V., Leypoldt, F., Simova, O., Thom, V., Friese, M. A., Prinz, I., Hölscher, C., Glatzel, M., Korn, T., Gerloff, C., Tolosa, E. & Magnus, T., 2012, In: BLOOD. 120, 18, p. 3793-3802 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ochronose
Breer, S., Amling, M., Püschel, K., Klein, A., Schulz, F. & Zustin, J., 2012, In: RECHTSMEDIZIN. 22, 1, p. 49-53 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Odontogenic myxomas are not associated with GNAS1 mutations.
Friedrich, R., Scheuer, H., Assaf, A., Grob, T. & Zustin, J., 2012, In: ANTICANCER RES. 32, 5, p. 2169-2172 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Opposite roles of FOXA1 and NKX2-1 in lung cancer progression.
Deutsch, L., Wrage, M., Koops, S., Glatzel, M., Uzunoglu, F. G., Kutup, A., Hinsch, A., Sauter, G., Izbicki, J. R., Pantel, K. & Wikman, H., 2012, In: GENE CHROMOSOME CANC. 51, 6, p. 618-629 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Origin and differentiation of breast nipple syringoma.
Boecker, W., Junkers, T., Reusch, M., Buerger, H., Korsching, E., Metze, D., Decker, T., Löning, T., Lange, A., Samoilova, V. & Buchwalow, I., 2012, In: SCI REP-UK. 2, p. 226Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Osteochondroma of the mandibular condyle. Report of a case with 5-year follow-up.
Friedrich, R., Scheuer, H., Fuhrmann, A., Hagel, C. & Zustin, J., 2012, In: ANTICANCER RES. 32, 10, p. 4553-4556 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
p65-Dependent production of interleukin-1β by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts.
Schulze, J., Riecken, K., Baranowsky, A., Streichert, T., Lange, T., Spiro, A. S., Albers, J., Seitz, S., Zustin, J., Amling, M., Fehse, B. & Schinke, T., 2012, In: CANCER LETT. 317, 1, p. 106-113 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Peroxiredoxins 3 and 4 are overexpressed in prostate cancer tissue and affect the proliferation of prostate cancer cells in vitro.
Ummanni, R., Barreto, F., Venz, S., Scharf, C., Barett, C., Mannsperger, H. A., Brase, J. C., Kuner, R., Schlomm, T., Sauter, G., Sültmann, H., Korf, U., Bokemeyer, C., Walther, R., Brümmendorf, T. & Balabanov, S., 2012, In: J PROTEOME RES. 11, 4, p. 2452-2466 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prognostic relevance of Bcl-2 overexpression in surgically treated prostate cancer is not caused by increased copy number or translocation of the gene.
Fleischmann, A., Huland, H., Mirlacher, M., Wilczak, W., Simon, R., Erbersdobler, A., Sauter, G. & Schlomm, T., 2012, In: PROSTATE. 72, 9, p. 991-997 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prognostic role and HER2 expression of circulating tumor cells in peripheral blood of patients prior to radical cystectomy: a prospective study.
Rink, M., Chun, F., Dahlem, R., Soave, A., Minner, S. J. P., Hansen, J., Stoupiec, M., Coith, C., Kluth, L., Ahyai, S., Friedrich, M. G., Shariat, S. F., Fisch, M., Pantel, K. & Riethdorf, S., 2012, In: EUR UROL. 61, 4, p. 810-817 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Protective role for CCR5 in murine lupus nephritis.
Turner, J. E., Paust, H-J., Mathey, S., Bramke, P., Krebs, C., Steinmetz, O., Velden, J., Haag, F., Stahl, R. A. K. & Panzer, U., 2012, In: AM J PHYSIOL-RENAL. 302, 11, p. 1503-1515 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PTEN deletion is rare but often homogeneous in gastric cancer.
Mina, S., Bohn, B., Simon, R., Krohn, A., Reeh, M., Arnold, D., Bokemeyer, C., Sauter, G., Izbicki, J. R., Marx, A. & Stahl, P., 2012, In: J CLIN PATHOL. 65, 8, p. 693-698 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Radiographic findings of odontogenic myxomas on conventional radiographs.
Friedrich, R., Scheuer, H., Fuhrmann, A., Zustin, J. & Assaf, A., 2012, In: ANTICANCER RES. 32, 5, p. 2173-2177 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rare oncogenic mutations of predictive markers for targeted therapy in triple-negative breast cancer.
Grob, T., Heilenkötter, U., Geist, S., Paluchowski, P., Wilke, C., Jänicke, F., Quaas, A., Wilczak, W., Choschzick, M., Sauter, G. & Lebeau, A., 2012, In: BREAST CANCER RES TR. 134, 2, p. 561-567 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevance of activated leukocyte cell adhesion molecule (ALCAM) in tumor tissue and sera of cervical cancer patients.
Henningsen, M., Kress, K., Kersten, J. F., Kilic, E., Choschzick, M., Zander, H., Müller, V., Mahner, S., Jänicke, F., Wölber, L. & Milde-Langosch, K., 2012, In: BMC CANCER. 12, p. 140Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevance of PTEN loss in brain metastasis formation in breast cancer patients.
Wikman, H., Lamszus, K., Detels, N., Uslar, L., Wrage, M., Benner, C., Hohensee, I., Ylstra, B., Eylmann, K., Zapatka, M., Sauter, G., Kemming, D., Glatzel, M., Müller, V., Westphal, M. & Pantel, K., 2012, In: BREAST CANCER RES. 14, 2, p. 49 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Renal IL-17 expression in human ANCA-associated glomerulonephritis.
Velden, J., Paust, H-J., Hoxha, E., Turner, J. E., Steinmetz, O., Wolf, G., Jabs, W. J., Özcan, F., Beige, J., Heering, P. J., Schröder, S., Kneißler, U., Disteldorf, E., Mittrücker, H. W., Stahl, R. A. K., Helmchen, U. & Panzer, U., 2012, In: AM J PHYSIOL-RENAL. 302, 12, p. 1663-1673 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of cyclin D1 amplification and expression in vulvar carcinomas.
Choschzick, M., Hess, S., Tennstedt, P., Holst, F., Bohlken, H., Gieseking, F., Mahner, S., Wölber, L., Simon, R. & Sauter, G., 2012, In: HUM PATHOL. 43, 9, p. 1386-1393 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of interleukin 16 in multiple myeloma.
Atanackovic, D., Hildebrandt, Y., Templin, J., Cao, Y., Keller, C., Panse, J., Meyer, S., Reinhard, H., Bartels, K., Lajmi, N., Sezer, O., Zander, A. R., Marx, A., Uhlig, R., Zustin, J., Bokemeyer, C. & Kröger, N., 2012, In: JNCI-J NATL CANCER I. 104, 13, p. 1005-1020 13.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of KCNMA1 in breast cancer.
Oeggerli, M., Tian, Y., Ruiz, C., Wijker, B., Sauter, G., Obermann, E., Güth, U., Zlobec, I., Sausbier, M., Kunzelmann, K. & Bubendorf, L., 2012, In: PLOS ONE. 7, 8, p. 41664 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of the polarity protein Scribble for podocyte differentiation and maintenance
Hartleben, B., Widmeier, E., Wanner, N., Schmidts, M., Kim, S. T., Schneider, L., Mayer, B., Kerjaschki, D., Miner, J. H., Walz, G. & Huber, T. B., 2012, In: PLOS ONE. 7, 5, p. e36705Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sef downregulation by Ras causes MEK1/2 to become aberrantly nuclear localized leading to polyploidy and neoplastic transformation.
Duhamel, S., Hébert, J., Gaboury, L., Bouchard, A., Simon, R., Sauter, G., Basik, M. & Meloche, S., 2012, In: CANCER RES. 72, 3, p. 626-635 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.
Kah, J., Wüstenberg, A., Keller, A., Sirma, H., Montalbano, R., Ocker, M., Volz, T., Dandri-Petersen, M., Tiegs, G. & Sass, G., 2012, In: ONCOL REP. 28, 3, p. 1077-1083 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sharpin contributes to TNFα dependent NFκB activation and anti-apoptotic signalling in hepatocytes.
Sieber, S., Lange, N., Kollmorgen, G., Erhardt, A., Quaas, A., Gontarewicz, A., Sass, G., Tiegs, G. & Kreienkamp, H-J., 2012, In: PLOS ONE. 7, 1, p. 29993 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Significant reduction of acute cardiac allograft rejection by selective janus kinase-1/3 inhibition using R507 and R545.
Deuse, T., Hua, X., Taylor, V., Stubendorff, M., Baluom, M., Chen, Y., Park, G., Velden, J., Streichert, T., Reichenspurner, H., Robbins, R. C. & Schrepfer, S., 2012, In: TRANSPLANTATION. 94, 7, p. 695-702 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Similar incidences of TP53 deletions in extramedullary organ infiltrations, soft tissue and osteolyses of patients with multiple myeloma.
Billecke, L., Murga-Penas, E-M., May, A. M., Engelhardt, M., Nagler, A., Leiba, M., Schiby, G., Kröger, N., Zustin, J., Marx, A., Matschke, J., Tiemann, M., Goekkurt, E., Bokemeyer, C. & Schilling, G., 2012, In: ANTICANCER RES. 32, 5, p. 2031-2034 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Studies of genomic imbalances and the MYB-NFIB gene fusion in polymorphous low-grade adenocarcinoma of the head and neck.
Persson, F., Fehr, A., Sundelin, K., Schulte, B., Löning, T. & Stenman, G., 2012, In: INT J ONCOL. 40, 1, p. 80-84 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Synchronous bronchioloalveolar and squamous cell lung cancer with different 18F-FDG avidity on PET/CT.
Derlin, T., Clauditz, T., Quaas, A. & Habermann, C., 2012, In: CLIN NUCL MED. 37, 10, p. 255-256 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers.
Tennstedt, P., Köster, P., Brüchmann, A., Mirlacher, M., Haese, A., Steuber, T., Sauter, G., Huland, H., Graefen, M., Schlomm, T., Minner, S. & Simon, R., 2012, In: INT J ONCOL. 40, 1, p. 261-268 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Y chromosome losses are exceedingly rare in prostate cancer and unrelated to patient age.
Stahl, P., Kilgué, A., Tennstedt, P., Minner, S. J. P., Krohn, A., Simon, R., Krause, G., Izbicki, J. R., Graefen, M., Sauter, G., Schlomm, T. & Wilczak, W., 2012, In: PROSTATE. 72, 8, p. 898-903 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Characterization of Enterobacter cloacae pneumonia: a single-center retrospective analysis.
Hennigs, J. K., Baumann, H. J., Schmiedel, S., Tennstedt, P., Sobottka, I., Bokemeyer, C., Kluge, S. & Klose, H., 01.12.2011, In: LUNG. 189, 6, p. 475-483 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review