PTEN deletion is rare but often homogeneous in gastric cancer.

Abstract

Gastric carcinoma is the second most frequent cause of cancer-related death worldwide. As PTEN is a potential modifier of tumour response to trastuzumab, a recently approved therapy in metastatic HER2 positive gastric cancer, the existence of PTEN deletions in primary gastric cancer was investigated.

Bibliographical data

Original languageEnglish
Article number8
ISSN0021-9746
Publication statusPublished - 2012
pubmed 22639407