PTEN deletion is rare but often homogeneous in gastric cancer.

Sormeh Mina; Benjamin Bohn; Ronald Simon; Antje Krohn; Matthias Reeh; Dirk Arnold; Carsten Bokemeyer; Guido Sauter; Jakob R. Izbicki; Andreas Marx; Phillip Stahl

PTEN deletion is rare but often homogeneous in gastric cancer.

Standard

PTEN deletion is rare but often homogeneous in gastric cancer. / Mina, Sormeh; Bohn, Benjamin; Simon, Ronald; Krohn, Antje; Reeh, Matthias; Arnold, Dirk; Bokemeyer, Carsten ; Sauter, Guido; Izbicki, Jakob R.; Marx, Andreas; Stahl, Phillip.

In: J CLIN PATHOL, Vol. 65, No. 8, 8, 2012, p. 693-698.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Mina, S, Bohn, B, Simon, R, Krohn, A, Reeh, M, Arnold, D, Bokemeyer, C , Sauter, G, Izbicki, JR, Marx, A & Stahl, P 2012, 'PTEN deletion is rare but often homogeneous in gastric cancer.', J CLIN PATHOL, vol. 65, no. 8, 8, pp. 693-698. <http://www.ncbi.nlm.nih.gov/pubmed/22639407?dopt=Citation>

APA

Mina, S., Bohn, B., Simon, R., Krohn, A., Reeh, M., Arnold, D., Bokemeyer, C., Sauter, G., Izbicki, J. R., Marx, A., & Stahl, P. (2012). PTEN deletion is rare but often homogeneous in gastric cancer. J CLIN PATHOL, 65(8), 693-698. [8]. http://www.ncbi.nlm.nih.gov/pubmed/22639407?dopt=Citation

Vancouver

Mina S, Bohn B, Simon R, Krohn A, Reeh M, Arnold D et al. PTEN deletion is rare but often homogeneous in gastric cancer. J CLIN PATHOL. 2012;65(8):693-698. 8.

Bibtex

@article{4b50a816772242999b111318bd99ebd6,

title = "PTEN deletion is rare but often homogeneous in gastric cancer.",

abstract = "Gastric carcinoma is the second most frequent cause of cancer-related death worldwide. As PTEN is a potential modifier of tumour response to trastuzumab, a recently approved therapy in metastatic HER2 positive gastric cancer, the existence of PTEN deletions in primary gastric cancer was investigated.",

keywords = "Germany, Humans, Male, Aged, Female, Middle Aged, Risk Factors, Immunohistochemistry, Predictive Value of Tests, Prognosis, Risk Assessment, Time Factors, Genetic Predisposition to Disease, Chi-Square Distribution, Homozygote, Kaplan-Meier Estimate, In Situ Hybridization, Fluorescence, *Gene Deletion, Receptor, erbB-2/analysis, Tumor Markers, Biological/*genetics, Adenocarcinoma/enzymology/*genetics/mortality/secondary, Hemizygote, PTEN Phosphohydrolase/*genetics, Stomach Neoplasms/enzymology/*genetics/mortality/pathology, Tissue Array Analysis/methods, Germany, Humans, Male, Aged, Female, Middle Aged, Risk Factors, Immunohistochemistry, Predictive Value of Tests, Prognosis, Risk Assessment, Time Factors, Genetic Predisposition to Disease, Chi-Square Distribution, Homozygote, Kaplan-Meier Estimate, In Situ Hybridization, Fluorescence, *Gene Deletion, Receptor, erbB-2/analysis, Tumor Markers, Biological/*genetics, Adenocarcinoma/enzymology/*genetics/mortality/secondary, Hemizygote, PTEN Phosphohydrolase/*genetics, Stomach Neoplasms/enzymology/*genetics/mortality/pathology, Tissue Array Analysis/methods",

author = "Sormeh Mina and Benjamin Bohn and Ronald Simon and Antje Krohn and Matthias Reeh and Dirk Arnold and Carsten Bokemeyer and Guido Sauter and Izbicki, {Jakob R.} and Andreas Marx and Phillip Stahl",

year = "2012",

language = "English",

volume = "65",

pages = "693--698",

journal = "J CLIN PATHOL",

issn = "0021-9746",

publisher = "BMJ PUBLISHING GROUP",

number = "8",

}

RIS

TY - JOUR

T1 - PTEN deletion is rare but often homogeneous in gastric cancer.

AU - Mina, Sormeh

AU - Bohn, Benjamin

AU - Simon, Ronald

AU - Krohn, Antje

AU - Reeh, Matthias

AU - Arnold, Dirk

AU - Bokemeyer, Carsten

AU - Sauter, Guido

AU - Izbicki, Jakob R.

AU - Marx, Andreas

AU - Stahl, Phillip

PY - 2012

Y1 - 2012

N2 - Gastric carcinoma is the second most frequent cause of cancer-related death worldwide. As PTEN is a potential modifier of tumour response to trastuzumab, a recently approved therapy in metastatic HER2 positive gastric cancer, the existence of PTEN deletions in primary gastric cancer was investigated.

AB - Gastric carcinoma is the second most frequent cause of cancer-related death worldwide. As PTEN is a potential modifier of tumour response to trastuzumab, a recently approved therapy in metastatic HER2 positive gastric cancer, the existence of PTEN deletions in primary gastric cancer was investigated.

KW - Germany

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Risk Factors

KW - Immunohistochemistry

KW - Predictive Value of Tests

KW - Prognosis

KW - Risk Assessment

KW - Time Factors

KW - Genetic Predisposition to Disease

KW - Chi-Square Distribution

KW - Homozygote

KW - Kaplan-Meier Estimate

KW - In Situ Hybridization, Fluorescence

KW - Gene Deletion

KW - Receptor, erbB-2/analysis

KW - Tumor Markers, Biological/genetics

KW - Adenocarcinoma/enzymology/genetics/mortality/secondary

KW - Hemizygote

KW - PTEN Phosphohydrolase/genetics

KW - Stomach Neoplasms/enzymology/genetics/mortality/pathology

KW - Tissue Array Analysis/methods