The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers.
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Abstract
Most tissue microarray studies have used a single 0.6-mm tissue core per donor tissue. It has been suggested that multiple cores per donor can increase the representativity of tissue microarray studies. To estimate the potential benefit of multiple cores, we analyzed Ki67 and p53 in triplet cores taken from three different areas of 3,261 prostate cancer tissue blocks. Both p53 and Ki67 labeling index were linked to advanced tumor stage (p
Bibliographical data
| Original language | English |
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| Article number | 1 |
| ISSN | 1019-6439 |
| Publication status | Published - 2012 |
| pubmed | 21956230 |
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