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The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers.

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The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers. / Tennstedt, Pierre; Köster, Patricia; Brüchmann, Andreas; Mirlacher, Martina; Haese, Alexander; Steuber, Thomas; Sauter, Guido; Huland, Hartwig; Graefen, Markus; Schlomm, Thorsten; Minner, Sarah; Simon, Ronald.

In: INT J ONCOL, Vol. 40, No. 1, 1, 2012, p. 261-268.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Tennstedt, P, Köster, P, Brüchmann, A, Mirlacher, M, Haese, A, Steuber, T, Sauter, G, Huland, H, Graefen, M, Schlomm, T, Minner, S & Simon, R 2012, 'The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers.', INT J ONCOL, vol. 40, no. 1, 1, pp. 261-268. <http://www.ncbi.nlm.nih.gov/pubmed/21956230?dopt=Citation>

APA

Tennstedt, P., Köster, P., Brüchmann, A., Mirlacher, M., Haese, A., Steuber, T., Sauter, G., Huland, H., Graefen, M., Schlomm, T., Minner, S., & Simon, R. (2012). The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers. INT J ONCOL, 40(1), 261-268. [1]. http://www.ncbi.nlm.nih.gov/pubmed/21956230?dopt=Citation

Vancouver

Tennstedt P, Köster P, Brüchmann A, Mirlacher M, Haese A, Steuber T et al. The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers. INT J ONCOL. 2012;40(1):261-268. 1.

Bibtex

@article{a1b4b94caca3417893a050fdb7e0c258,
title = "The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers.",
abstract = "Most tissue microarray studies have used a single 0.6-mm tissue core per donor tissue. It has been suggested that multiple cores per donor can increase the representativity of tissue microarray studies. To estimate the potential benefit of multiple cores, we analyzed Ki67 and p53 in triplet cores taken from three different areas of 3,261 prostate cancer tissue blocks. Both p53 and Ki67 labeling index were linked to advanced tumor stage (p",
keywords = "Humans, Male, Aged, Middle Aged, Immunohistochemistry, Neoplasm Staging, Protein Array Analysis/methods, Neoplasm Grading, Ki-67 Antigen/*analysis/biosynthesis, Prostatic Neoplasms/*chemistry/metabolism/pathology, Tumor Markers, Biological/*analysis/biosynthesis, Tumor Suppressor Protein p53/*analysis/biosynthesis, Humans, Male, Aged, Middle Aged, Immunohistochemistry, Neoplasm Staging, Protein Array Analysis/methods, Neoplasm Grading, Ki-67 Antigen/*analysis/biosynthesis, Prostatic Neoplasms/*chemistry/metabolism/pathology, Tumor Markers, Biological/*analysis/biosynthesis, Tumor Suppressor Protein p53/*analysis/biosynthesis",
author = "Pierre Tennstedt and Patricia K{\"o}ster and Andreas Br{\"u}chmann and Martina Mirlacher and Alexander Haese and Thomas Steuber and Guido Sauter and Hartwig Huland and Markus Graefen and Thorsten Schlomm and Sarah Minner and Ronald Simon",
year = "2012",
language = "English",
volume = "40",
pages = "261--268",
journal = "INT J ONCOL",
issn = "1019-6439",
publisher = "Spandidos Publications",
number = "1",

}

RIS

TY - JOUR

T1 - The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers.

AU - Tennstedt, Pierre

AU - Köster, Patricia

AU - Brüchmann, Andreas

AU - Mirlacher, Martina

AU - Haese, Alexander

AU - Steuber, Thomas

AU - Sauter, Guido

AU - Huland, Hartwig

AU - Graefen, Markus

AU - Schlomm, Thorsten

AU - Minner, Sarah

AU - Simon, Ronald

PY - 2012

Y1 - 2012

N2 - Most tissue microarray studies have used a single 0.6-mm tissue core per donor tissue. It has been suggested that multiple cores per donor can increase the representativity of tissue microarray studies. To estimate the potential benefit of multiple cores, we analyzed Ki67 and p53 in triplet cores taken from three different areas of 3,261 prostate cancer tissue blocks. Both p53 and Ki67 labeling index were linked to advanced tumor stage (p

AB - Most tissue microarray studies have used a single 0.6-mm tissue core per donor tissue. It has been suggested that multiple cores per donor can increase the representativity of tissue microarray studies. To estimate the potential benefit of multiple cores, we analyzed Ki67 and p53 in triplet cores taken from three different areas of 3,261 prostate cancer tissue blocks. Both p53 and Ki67 labeling index were linked to advanced tumor stage (p

KW - Humans

KW - Male

KW - Aged

KW - Middle Aged

KW - Immunohistochemistry

KW - Neoplasm Staging

KW - Protein Array Analysis/methods

KW - Neoplasm Grading

KW - Ki-67 Antigen/analysis/biosynthesis

KW - Prostatic Neoplasms/chemistry/metabolism/pathology

KW - Tumor Markers, Biological/analysis/biosynthesis

KW - Tumor Suppressor Protein p53/analysis/biosynthesis

KW - Humans

KW - Male

KW - Aged

KW - Middle Aged

KW - Immunohistochemistry

KW - Neoplasm Staging

KW - Protein Array Analysis/methods

KW - Neoplasm Grading

KW - Ki-67 Antigen/analysis/biosynthesis

KW - Prostatic Neoplasms/chemistry/metabolism/pathology

KW - Tumor Markers, Biological/analysis/biosynthesis

KW - Tumor Suppressor Protein p53/analysis/biosynthesis

M3 - SCORING: Journal article

VL - 40

SP - 261

EP - 268

JO - INT J ONCOL

JF - INT J ONCOL

SN - 1019-6439

IS - 1

M1 - 1

ER -