Department of Osteology and Biomechanics
Publications
- 2022
New and innovative biomaterials, techniques and therapy concepts: Biologization in maxillofacial surgery, oral surgery and dentistry is in full swing. PRF, PRGF, PRP, blood plasma-stabilized augmentations, supplementation of micronutrients and vitamins - what opportunities do such "biological" approaches actually offer? We introduce them here
Smeets, R., Henningsen, A., Zernial, O., Stürmer, E., Fiedler, I., Schäfer, S., Gosau, M., Gaudin, R., Stolzer, C., Reinelt, A. & Fuest, S., 2022, In: GMS INTERDISCIP PLAS. 11, Doc05.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Prevention of Hypomineralization In Auditory Ossicles of Vitamin D Receptor (Vdr) Deficient Mice
Delsmann, M. M., Peichl, J., Yorgan, T., Beil, F. T., Amling, M., Demay, M. B. & Rolvien, T., 2022, In: FRONT ENDOCRINOL. 13, 901265.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
P-Type Lectins
Dahms, N., Braulke, T. & Varki, A., 2022, Essentials of Glycobiology. Varki, A. (ed.). 4 ed. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, p. 443 - 454 12 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2021
Autosomal recessive hypophosphatemic rickets type 2 (ARHR2) due to ENPP1-deficiency
Höppner, J., Kornak, U., Sinningen, K., Rutsch, F., Oheim, R. & Grasemann, C., 12.2021, In: BONE. 153, 116111.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Conductive hearing loss in the Hyp mouse model of X-linked hypophosphatemia is accompanied by hypomineralization of the auditory ossicles
Delsmann, M. M., Seist, R., Stürznickel, J., Schmidt, F. N., Mansour, A., Kobelski, M. M., Broocks, G., Peichl, J., Oheim, R., Praetorius, M., Schinke, T., Amling, M., Demay, M. B., Stankovic, K. M. & Rolvien, T., 12.2021, In: J BONE MINER RES. 36, 12, p. 2317-2328 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pathogenic variants in GNPTAB and GNPTG encoding distinct subunits of GlcNAc-1-phosphotransferase differentially impact bone resorption in patients with mucolipidosis type II and III
Di Lorenzo, G., Westermann, L. M., Schinke, T., Stürznickel, J., Ludwig, N. F., Ammer, L. S., Baranowsky, A., Ahmadi, S., Pourbarkhordariesfandabadi, E., Breyer, S. R., Board, T. N., Foster, A., Mercer, J., Tylee, K., Velho, R. V., Schweizer, M., Renné, T., Braulke, T., Randon, D. N., Sperb-Ludwig, F., de Camargo Pinto, L. L., Moreno, C. A., Cavalcanti, D. P., Amling, M., Kutsche, K., Winter, D., Muschol, N. M., Schwartz, I. V. D., Rolvien, T., Danyukova, T., Schinke, T. & Pohl, S., 12.2021, In: GENET MED. 23, 12, p. 2369-2377 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Wnt1 Promotes Cementum and Alveolar Bone Growth in a Time-Dependent Manner
Nottmeier, C., Liao, N., Simon, A., Decker, M. G., Luther, J., Schweizer, M., Yorgan, T., Kaucka, M., Bockamp, E., Kahl-Nieke, B., Amling, M., Schinke, T., Petersen, J. & Koehne, T., 12.2021, In: J DENT RES. 100, 13, p. 1501-1509 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The WNT1G177C mutation specifically affects skeletal integrity in a mouse model of osteogenesis imperfecta type XV
Vollersen, N., Zhao, W., Rolvien, T., Lange, F., Schmidt, F. N., Sonntag, S., Shmerling, D., von Kroge, S., Stockhausen, K. E., Sharaf, A., Schweizer, M., Karsak, M., Busse, B., Bockamp, E., Semler, O., Amling, M., Oheim, R., Schinke, T. & Yorgan, T. A., 10.11.2021, In: BONE RES. 9, 1, p. 48Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Decreased Trabecular Bone Mass in Col22a1-Deficient Mice
Zhao, W., Wiedemann, P., Wölfel, E. M., Neven, M., Peters, S., Imhof, T., Koch, M., Busse, B., Amling, M., Schinke, T. & Yorgan, T. A., 04.11.2021, In: CELLS-BASEL. 10, 11, 3020.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allograft Chip Incorporation in Acetabular Reconstruction: Multiscale Characterization Revealing Osteoconductive Capacity
Butscheidt, S., von Kroge, S., Stürznickel, J., Beil, F. T., Gehrke, T., Püschel, K., Amling, M., Hahn, M. & Rolvien, T., 03.11.2021, In: J BONE JOINT SURG AM. 103, 21, p. 1996-2005 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Challenges in the management of tumor-induced osteomalacia (TIO)
Brandi, M. L., Clunie, G. P. R., Houillier, P., Jan de Beur, S. M., Minisola, S., Oheim, R. & Seefried, L., 11.2021, In: BONE. 152, p. 116064Research output: SCORING: Contribution to journal › SCORING: Review article › Research
EXTH-70. ESTABLISHMENT OF INTRAVENTRICULAR SHH INHIBITION AS A THERAPEUTIC OPTION IN YOUNG PATIENTS WITH MEDULLOBLASTOMA
Kresbach, C., Schoof, M., Leven, T., Holst, L., Yorgan, T. A., Wrzeszcz, A., Rutkowski, S. J. & Schüller, U., 11.2021, In: NEURO-ONCOLOGY. 23, Supplement_6, p. vi179Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
Reorganization of the osteocyte lacuno-canalicular network characteristics in tumor sites of an immunocompetent murine model of osteotropic cancers
Hemmatian, H., Conrad, S., Furesi, G., Mletzko, K., Krug, J., Failla, A. V., Kuhlmann, J. D., Rauner, M., Busse, B. & Jähn-Rickert, K., 11.2021, In: BONE. 152, 116074.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prevalence of low alkaline phosphatase activity in laboratory assessment: Is hypophosphatasia an underdiagnosed disease?
Schmidt, T., Schmidt, C., Amling, M., Kramer, J. & Barvencik, F., 28.10.2021, In: ORPHANET J RARE DIS. 16, 1, 452.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone loss recovery in mice following microgravity with concurrent bone-compartment-specific osteocyte characteristics
von Kroge, S., Wölfel, E. M., Buravkova, L. B., Atiakshin, D. A., Markina, E. A., Schinke, T., Rolvien, T., Busse, B. & Jähn-Rickert, K., 13.10.2021, In: EUR CELLS MATER. 42, p. 220-231 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype
Soldati, C., Lopez-Fabuel, I., Wanderlingh, L. G., Garcia-Macia, M., Monfregola, J., Esposito, A., Napolitano, G., Guevara-Ferrer, M., Scotto Rosato, A., Krogsaeter, E. K., Paquet, D., Grimm, C. M., Montefusco, S., Braulke, T., Storch, S., Mole, S. E., De Matteis, M. A., Ballabio, A., Sampaio, J. L., McKay, T., Johannes, L., Bolaños, J. P. & Medina, D. L., 07.10.2021, In: EMBO MOL MED. 13, 10, e13742.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone microarchitecture of the distal fibula assessed by HR-pQCT
Stürznickel, J., Schmidt, F. N., Schäfer, H. S., Beil, F. T., Frosch, K-H., Schlickewei, C., Amling, M., Barg, A. & Rolvien, T., 10.2021, In: BONE. 151, 116057.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diagnostic yield of cone beam computed tomography for small foreign body detection in the hand in comparison with radiography, MSCT and MRI: an ex vivo study
Jandl, N. M., Rolvien, T., Rupp, T., Schumacher, U., Püschel, K., Maas, K-J., Amling, M., Henes, F. O. & Spink, C., 10.2021, In: INJURY. 52, 10, p. 2841-2847 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Loss of glucocorticoid rhythm induces an osteoporotic phenotype in female mice
Schilperoort, M., Kroon, J., Kooijman, S., Smit, A. E., Gentenaar, M., Mletzko, K., Schmidt, F. N., van Ruijven, L., Busse, B., Pereira, A. M., Appelman-Dijkstra, N. M., Bravenboer, N., Rensen, P. C. N., Meijer, O. C. & Winter, E. M., 10.2021, In: AGING CELL. 20, 10, e13474.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Muskuloskelettale Labordiagnostik im Leistungssport
Delsmann, M. M., Stürznickel, J., Amling, M., Ueblacker, P. & Rolvien, T., 09.2021, In: ORTHOPADE. 50, 9, p. 700-712 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Skeletal characterization in a patient with Hajdu-Cheney syndrome undergoing total knee arthroplasty
von Vopelius, E., Oheim, R., Amling, M., Rolvien, T. & Beil, F. T., 09.2021, In: OSTEOPOROSIS INT. 32, 9, p. 1899-1904 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cranial bone flap resorption-pathological features and their implications for clinical treatment
Göttsche, J., Mende, K. C., Schram, A., Westphal, M., Amling, M., Regelsberger, J., Sauvigny, T. & Hahn, M., 08.2021, In: NEUROSURG REV. 44, 4, p. 2253-2260 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High prevalence and undertreatment of osteoporosis in elderly patients undergoing total hip arthroplasty
Delsmann, M. M., Strahl, A., Mühlenfeld, M., Jandl, N. M., Beil, F. T., Ries, C. & Rolvien, T., 08.2021, In: OSTEOPOROSIS INT. 32, 8, p. 1661-1668 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Potential Role of Perilacunar Remodeling in the Progression of Osteoporosis and Implications on Age-Related Decline in Fracture Resistance of Bone
Jähn-Rickert, K. & Zimmermann, E. A., 08.2021, In: CURR OSTEOPOROS REP. 19, 4, p. 391-402 12 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Bone microarchitecture in patients with autoimmune hepatitis
Schmidt, C., Stürznickel, J., Strahl, A., Oheim, R., Weiler-Normann, C., Sebode, M., Barvencik, F., Lohse, A. W., Schinke, T., Amling, M., Schramm, C. & Rolvien, T., 07.2021, In: J BONE MINER RES. 36, 7, p. 1316-1325 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone quality analysis of jaw bones in individuals with type 2 diabetes mellitus-post mortem anatomical and microstructural evaluation
Rodic, T., Wölfel, E. M., Milovanovic, P., Fiedler, I. A. K., Cvetkovic, D., Jähn, K., Amling, M., Sopta, J., Nikolic, S., Zivkovic, V., Busse, B. & Djuric, M., 07.2021, In: CLIN ORAL INVEST. 25, 7, p. 4377-4400 24 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evaluation of postural stability in patients screened for osteoporosis: A retrospective study of 1086 cases
Simon, A., Rupp, T., Hoenig, T., Vettorazzi, E., Amling, M. & Rolvien, T., 07.2021, In: Gait & posture. 88, p. 304-310 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mucolipidosis type II and type III: a systematic review of 843 published cases
Dogterom, E. J., Wagenmakers, M. A. E. M., Wilke, M., Demirdas, S., Muschol, N. M., Pohl, S., van der Meijden, J. C., Rizopoulos, D., van der Ploeg, A. T. & Oussoren, E., 25.06.2021, In: GENET MED. 23, 11, p. 2047-2056 10 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Bacterial adhesion characteristics on implant materials for intervertebral cages: titanium or PEEK for spinal infections?
Krätzig, T., Mende, K. C., Mohme, M., von Kroge, S., Stangenberg, M., Dreimann, M., Westphal, M., Weisselberg, S. & Eicker, S. O., 06.2021, In: EUR SPINE J. 30, 6, p. 1774-1782 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Compound heterozygous frameshift mutations in MESD cause a lethal syndrome suggestive of osteogenesis imperfecta type XX
Stürznickel, J., Jähn-Rickert, K., Zustin, J., Hennig, F., Delsmann, M. M., Schoner, K., Rehder, H., Kreczy, A., Schinke, T., Amling, M., Kornak, U. & Oheim, R., 06.2021, In: J BONE MINER RES. 36, 6, p. 1077-1087 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevant genetic variants are common in women with pregnancy and lactation-associated osteoporosis (PLO) and predispose to more severe clinical manifestations
Butscheidt, S. K., Tsourdi, E., Rolvien, T., Delsmann, A., Stürznickel, J., Barvencik, F., Jakob, F., Hofbauer, L. C., Mundlos, S., Kornak, U., Seefried, L. & Oheim, R., 06.2021, In: BONE. 147, 115911.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In Vivo Analysis of the Biocompatibility and Bone Healing Capacity of a Novel Bone Grafting Material Combined with Hyaluronic Acid
Pröhl, A., Batinic, M., Alkildani, S., Hahn, M., Radenkovic, M., Najman, S., Jung, O. & Barbeck, M., 01.05.2021, In: INT J MOL SCI. 22, 9, 4818.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bilateral Looser zones or pseudofractures in the anteromedial tibia as a component of medial tibial stress syndrome in athletes
Stürznickel, J., Jandl, N. M., Delsmann, M. M., von Vopelius, E., Barvencik, F., Amling, M., Ueblacker, P., Rolvien, T. & Oheim, R., 05.2021, In: KNEE SURG SPORT TR A. 29, 5, p. 1644-1650 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Response of the ENPP1-deficient skeletal phenotype to oral phosphate supplementation and/or enzyme replacement therapy: Comparative studies in Humans and Mice
Ferreira, C. R., Kavanagh, D., Oheim, R., Zimmerman, K., Stürznickel, J., Li, X., Stabach, P., Rettig, R. L., Calderone, L., MacKichan, C., Wang, A., Hutchinson, H. A., Nelson, T., Tommassini, S. M., von Kroge, S., Fiedler, I. A. K., Lester, E. R., Moeckel, G. W., Busse, B., Schinke, T., Carpenter, T. O., Levine, M. A., Horwowitz, M. C. & Braddock, D. T., 05.2021, In: J BONE MINER RES. 36, 5, p. 942-955 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TFEB-deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
Sass, F., Schlein, C., Jaeckstein, M. Y., Pertzborn, P., Schweizer, M., Schinke, T., Ballabio, A., Scheja, L., Heeren, J. & Fischer, A. W., 05.2021, In: MOL METAB. 47, p. 101173Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neurofibromatosis Type 1 With Cherubism-like Phenotype, Multiple Osteolytic Bone Lesions of Lower Extremities, and Alagille-syndrome: Case Report With Literature Survey
Friedrich, R. E., Zustin, J., Luebke, A. M., Rosenbaum, T., Gosau, M., Hagel, C., Kohlrusch, F. K., Wieland, I. & Zenker, M., 30.04.2021, In: IN VIVO. 35, 3, p. 1711-1736 26 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Variability in stem taper surface topography affects the degree of corrosion and fretting in total hip arthroplasty
Stockhausen, K. E., Riedel, C., Belinski, A. V., Rothe, D., Gehrke, T., Klebig, F., Gebauer, M., Amling, M., Citak, M. & Busse, B., 30.04.2021, In: SCI REP-UK. 11, 1, p. 9348Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Silk Fiber-Reinforced Hyaluronic Acid-Based Hydrogel for Cartilage Tissue Engineering
Weitkamp, J-T., Wöltje, M., Nußpickel, B., Schmidt, F. N., Aibibu, D., Bayer, A., Eglin, D., Armiento, A. R., Arnold, P., Cherif, C., Lucius, R., Smeets, R., Kurz, B. & Behrendt, P., 31.03.2021, In: INT J MOL SCI. 22, 7, 3635.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Weightbearing Computed Tomography as a Novel Imaging Modality: Assessment of Peritalar Instability
Schlickewei, C., Steadman, J., Stürznickel, J., Krähenbühl, N., Frosch, K-H. & International WBCT Society, 28.03.2021, In: Fuß & Sprunggelenk. p. 2-10 9 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Safety and performance of biodegradable magnesium-based implants in children and adolescents
Stürznickel, J., Delsmann, M. M., Jungesblut, O., Stücker, R., Knorr, C., Rolvien, T., Kertai, M. & Rupprecht, M., 15.03.2021, In: INJURY. 52, 8, p. 2265-2271Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevance of in-depth skeletal assessment by high-resolution peripheral quantitative computed tomography (HR-pQCT) in orthopedics and trauma surgery
Stürznickel, J. & Schmidt, F., 10.03.2021, In: Fuß & Sprunggelenk. 19, 1, p. 19-26Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Genotype-Phenotype Associations in 72 Adults with Suspected ALPL-Associated Hypophosphatasia
Jandl, N. M., Schmidt, T., Rolvien, T., Stürznickel, J., Chrysostomou, K., von Vopelius, E., Volk, A. E., Schinke, T., Kubisch, C., Amling, M. & Barvencik, F., 03.2021, In: CALCIFIED TISSUE INT. 108, 3, p. 288-301 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Is hematopoietic stem cell transplantation a therapeutic option for mucolipidosis type II?
Ammer, L. S., Pohl, S., Breyer, S. R., Aries, C., Denecke, J., Perez, A., Petzoldt, M., Schrum, J., Müller, I. & Muschol, N. M., 03.2021, In: MOL GENET METAB REP. 26, 100704.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Skeletal Biology and Disease Modeling in Zebrafish
Dietrich, K., Fiedler, I. AK., Kurzyukova, A., López-Delgado, A. C., McGowan, L. M., Geurtzen, K., Hammond, C. L., Busse, B. & Knopf, F., 03.2021, In: J BONE MINER RES. 36, 3, p. 436-458 23 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis
Hinz, N., Baranowsky, A., Horn, M., Kriegs, M., Sibbertsen, F., Smit, D. J., Clezardin, P., Lange, T., Schinke, T. & Jücker, M., 18.02.2021, In: CELLS-BASEL. 10, 2, 430.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers
Zwirner, J., Safavi, S., Scholze, M., Li, K. C., Waddell, J. N., Busse, B., Ondruschka, B. & Hammer, N., 12.02.2021, In: SCI REP-UK. 11, 1, 3721.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone mineral density assessment by DXA in rheumatic patients with end-stage osteoarthritis undergoing total joint arthroplasty
Mühlenfeld, M., Strahl, A., Bechler, U., Jandl, N. M., Hubert, J. & Rolvien, T., 11.02.2021, In: BMC MUSCULOSKEL DIS. 22, 1, p. 173Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transgenic inhibition of interleukin-6 trans-signaling does not prevent skeletal pathologies in mucolipidosis type II mice
Westermann, L. M., Baranowsky, A., Di Lorenzo, G., Danyukova, T., Soul, J., Schwartz, J-M., Hendrickx, G., Amling, M., Rose-John, S., Garbers, C., Schinke, T. & Pohl, S., 11.02.2021, In: SCI REP-UK. 11, 1, p. 3556Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone healing and reactivation of remodeling under asfotase alfa therapy in adult patients with pediatric-onset hypophosphatasia
Stürznickel, J., Schmidt, F. N., von Vopelius, E., Delsmann, M. M., Schmidt, C., Jandl, N. M., Oheim, R. & Barvencik, F., 02.2021, In: BONE. 143, p. 115794Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical and Radiological Characterization of Patients with Immobilizing and Progressive Stress Fractures in Methotrexate Osteopathy
Rolvien, T., Jandl, N. M., Stürznickel, J., Beil, F. T., Kötter, I., Oheim, R., Lohse, A. W., Barvencik, F. & Amling, M., 02.2021, In: CALCIFIED TISSUE INT. 108, 2, p. 219-230 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review