Department of Osteology and Biomechanics

Publications

  1. 2022
  2. Prevention of Hypomineralization In Auditory Ossicles of Vitamin D Receptor (Vdr) Deficient Mice

    Delsmann, M. M., Peichl, J., Yorgan, T., Beil, F. T., Amling, M., Demay, M. B. & Rolvien, T., 2022, In: FRONT ENDOCRINOL. 13, 901265.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. P-Type Lectins

    Dahms, N., Braulke, T. & Varki, A., 2022, Essentials of Glycobiology. Varki, A. (ed.). 4 ed. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, p. 443 - 454 12 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  4. 2021
  5. Autosomal recessive hypophosphatemic rickets type 2 (ARHR2) due to ENPP1-deficiency

    Höppner, J., Kornak, U., Sinningen, K., Rutsch, F., Oheim, R. & Grasemann, C., 12.2021, In: BONE. 153, 116111.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  6. Conductive hearing loss in the Hyp mouse model of X-linked hypophosphatemia is accompanied by hypomineralization of the auditory ossicles

    Delsmann, M. M., Seist, R., Stürznickel, J., Schmidt, F. N., Mansour, A., Kobelski, M. M., Broocks, G., Peichl, J., Oheim, R., Praetorius, M., Schinke, T., Amling, M., Demay, M. B., Stankovic, K. M. & Rolvien, T., 12.2021, In: J BONE MINER RES. 36, 12, p. 2317-2328 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Pathogenic variants in GNPTAB and GNPTG encoding distinct subunits of GlcNAc-1-phosphotransferase differentially impact bone resorption in patients with mucolipidosis type II and III

    Di Lorenzo, G., Westermann, L. M., Schinke, T., Stürznickel, J., Ludwig, N. F., Ammer, L. S., Baranowsky, A., Ahmadi, S., Pourbarkhordariesfandabadi, E., Breyer, S. R., Board, T. N., Foster, A., Mercer, J., Tylee, K., Velho, R. V., Schweizer, M., Renné, T., Braulke, T., Randon, D. N., Sperb-Ludwig, F., de Camargo Pinto, L. L., Moreno, C. A., Cavalcanti, D. P., Amling, M., Kutsche, K., Winter, D., Muschol, N. M., Schwartz, I. V. D., Rolvien, T., Danyukova, T., Schinke, T. & Pohl, S., 12.2021, In: GENET MED. 23, 12, p. 2369-2377 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Wnt1 Promotes Cementum and Alveolar Bone Growth in a Time-Dependent Manner

    Nottmeier, C., Liao, N., Simon, A., Decker, M. G., Luther, J., Schweizer, M., Yorgan, T., Kaucka, M., Bockamp, E., Kahl-Nieke, B., Amling, M., Schinke, T., Petersen, J. & Koehne, T., 12.2021, In: J DENT RES. 100, 13, p. 1501-1509 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. The WNT1G177C mutation specifically affects skeletal integrity in a mouse model of osteogenesis imperfecta type XV

    Vollersen, N., Zhao, W., Rolvien, T., Lange, F., Schmidt, F. N., Sonntag, S., Shmerling, D., von Kroge, S., Stockhausen, K. E., Sharaf, A., Schweizer, M., Karsak, M., Busse, B., Bockamp, E., Semler, O., Amling, M., Oheim, R., Schinke, T. & Yorgan, T. A., 10.11.2021, In: BONE RES. 9, 1, p. 48

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Decreased Trabecular Bone Mass in Col22a1-Deficient Mice

    Zhao, W., Wiedemann, P., Wölfel, E. M., Neven, M., Peters, S., Imhof, T., Koch, M., Busse, B., Amling, M., Schinke, T. & Yorgan, T. A., 04.11.2021, In: CELLS-BASEL. 10, 11, 3020.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Allograft Chip Incorporation in Acetabular Reconstruction: Multiscale Characterization Revealing Osteoconductive Capacity

    Butscheidt, S., von Kroge, S., Stürznickel, J., Beil, F. T., Gehrke, T., Püschel, K., Amling, M., Hahn, M. & Rolvien, T., 03.11.2021, In: J BONE JOINT SURG AM. 103, 21, p. 1996-2005 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Challenges in the management of tumor-induced osteomalacia (TIO)

    Brandi, M. L., Clunie, G. P. R., Houillier, P., Jan de Beur, S. M., Minisola, S., Oheim, R. & Seefried, L., 11.2021, In: BONE. 152, p. 116064

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  13. EXTH-70. ESTABLISHMENT OF INTRAVENTRICULAR SHH INHIBITION AS A THERAPEUTIC OPTION IN YOUNG PATIENTS WITH MEDULLOBLASTOMA

    Kresbach, C., Schoof, M., Leven, T., Holst, L., Yorgan, T. A., Wrzeszcz, A., Rutkowski, S. J. & Schüller, U., 11.2021, In: NEURO-ONCOLOGY. 23, Supplement_6, p. vi179

    Research output: SCORING: Contribution to journalConference abstract in journalResearchpeer-review

  14. Reorganization of the osteocyte lacuno-canalicular network characteristics in tumor sites of an immunocompetent murine model of osteotropic cancers

    Hemmatian, H., Conrad, S., Furesi, G., Mletzko, K., Krug, J., Failla, A. V., Kuhlmann, J. D., Rauner, M., Busse, B. & Jähn-Rickert, K., 11.2021, In: BONE. 152, 116074.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Prevalence of low alkaline phosphatase activity in laboratory assessment: Is hypophosphatasia an underdiagnosed disease?

    Schmidt, T., Schmidt, C., Amling, M., Kramer, J. & Barvencik, F., 28.10.2021, In: ORPHANET J RARE DIS. 16, 1, 452.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Bone loss recovery in mice following microgravity with concurrent bone-compartment-specific osteocyte characteristics

    von Kroge, S., Wölfel, E. M., Buravkova, L. B., Atiakshin, D. A., Markina, E. A., Schinke, T., Rolvien, T., Busse, B. & Jähn-Rickert, K., 13.10.2021, In: EUR CELLS MATER. 42, p. 220-231 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype

    Soldati, C., Lopez-Fabuel, I., Wanderlingh, L. G., Garcia-Macia, M., Monfregola, J., Esposito, A., Napolitano, G., Guevara-Ferrer, M., Scotto Rosato, A., Krogsaeter, E. K., Paquet, D., Grimm, C. M., Montefusco, S., Braulke, T., Storch, S., Mole, S. E., De Matteis, M. A., Ballabio, A., Sampaio, J. L., McKay, T., Johannes, L., Bolaños, J. P. & Medina, D. L., 07.10.2021, In: EMBO MOL MED. 13, 10, e13742.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Bone microarchitecture of the distal fibula assessed by HR-pQCT

    Stürznickel, J., Schmidt, F. N., Schäfer, H. S., Beil, F. T., Frosch, K-H., Schlickewei, C., Amling, M., Barg, A. & Rolvien, T., 10.2021, In: BONE. 151, 116057.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Diagnostic yield of cone beam computed tomography for small foreign body detection in the hand in comparison with radiography, MSCT and MRI: an ex vivo study

    Jandl, N. M., Rolvien, T., Rupp, T., Schumacher, U., Püschel, K., Maas, K-J., Amling, M., Henes, F. O. & Spink, C., 10.2021, In: INJURY. 52, 10, p. 2841-2847 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Loss of glucocorticoid rhythm induces an osteoporotic phenotype in female mice

    Schilperoort, M., Kroon, J., Kooijman, S., Smit, A. E., Gentenaar, M., Mletzko, K., Schmidt, F. N., van Ruijven, L., Busse, B., Pereira, A. M., Appelman-Dijkstra, N. M., Bravenboer, N., Rensen, P. C. N., Meijer, O. C. & Winter, E. M., 10.2021, In: AGING CELL. 20, 10, e13474.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Muskuloskelettale Labordiagnostik im Leistungssport

    Delsmann, M. M., Stürznickel, J., Amling, M., Ueblacker, P. & Rolvien, T., 09.2021, In: ORTHOPADE. 50, 9, p. 700-712 13 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  22. Skeletal characterization in a patient with Hajdu-Cheney syndrome undergoing total knee arthroplasty

    von Vopelius, E., Oheim, R., Amling, M., Rolvien, T. & Beil, F. T., 09.2021, In: OSTEOPOROSIS INT. 32, 9, p. 1899-1904 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Cranial bone flap resorption-pathological features and their implications for clinical treatment

    Göttsche, J., Mende, K. C., Schram, A., Westphal, M., Amling, M., Regelsberger, J., Sauvigny, T. & Hahn, M., 08.2021, In: NEUROSURG REV. 44, 4, p. 2253-2260 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. High prevalence and undertreatment of osteoporosis in elderly patients undergoing total hip arthroplasty

    Delsmann, M. M., Strahl, A., Mühlenfeld, M., Jandl, N. M., Beil, F. T., Ries, C. & Rolvien, T., 08.2021, In: OSTEOPOROSIS INT. 32, 8, p. 1661-1668 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Potential Role of Perilacunar Remodeling in the Progression of Osteoporosis and Implications on Age-Related Decline in Fracture Resistance of Bone

    Jähn-Rickert, K. & Zimmermann, E. A., 08.2021, In: CURR OSTEOPOROS REP. 19, 4, p. 391-402 12 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  26. Bone microarchitecture in patients with autoimmune hepatitis

    Schmidt, C., Stürznickel, J., Strahl, A., Oheim, R., Weiler-Normann, C., Sebode, M., Barvencik, F., Lohse, A. W., Schinke, T., Amling, M., Schramm, C. & Rolvien, T., 07.2021, In: J BONE MINER RES. 36, 7, p. 1316-1325 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Bone quality analysis of jaw bones in individuals with type 2 diabetes mellitus-post mortem anatomical and microstructural evaluation

    Rodic, T., Wölfel, E. M., Milovanovic, P., Fiedler, I. A. K., Cvetkovic, D., Jähn, K., Amling, M., Sopta, J., Nikolic, S., Zivkovic, V., Busse, B. & Djuric, M., 07.2021, In: CLIN ORAL INVEST. 25, 7, p. 4377-4400 24 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Evaluation of postural stability in patients screened for osteoporosis: A retrospective study of 1086 cases

    Simon, A., Rupp, T., Hoenig, T., Vettorazzi, E., Amling, M. & Rolvien, T., 07.2021, In: Gait & posture. 88, p. 304-310 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Mucolipidosis type II and type III: a systematic review of 843 published cases

    Dogterom, E. J., Wagenmakers, M. A. E. M., Wilke, M., Demirdas, S., Muschol, N. M., Pohl, S., van der Meijden, J. C., Rizopoulos, D., van der Ploeg, A. T. & Oussoren, E., 25.06.2021, In: GENET MED. 23, 11, p. 2047-2056 10 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  30. Bacterial adhesion characteristics on implant materials for intervertebral cages: titanium or PEEK for spinal infections?

    Krätzig, T., Mende, K. C., Mohme, M., von Kroge, S., Stangenberg, M., Dreimann, M., Westphal, M., Weisselberg, S. & Eicker, S. O., 06.2021, In: EUR SPINE J. 30, 6, p. 1774-1782 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Compound heterozygous frameshift mutations in MESD cause a lethal syndrome suggestive of osteogenesis imperfecta type XX

    Stürznickel, J., Jähn-Rickert, K., Zustin, J., Hennig, F., Delsmann, M. M., Schoner, K., Rehder, H., Kreczy, A., Schinke, T., Amling, M., Kornak, U. & Oheim, R., 06.2021, In: J BONE MINER RES. 36, 6, p. 1077-1087 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Relevant genetic variants are common in women with pregnancy and lactation-associated osteoporosis (PLO) and predispose to more severe clinical manifestations

    Butscheidt, S. K., Tsourdi, E., Rolvien, T., Delsmann, A., Stürznickel, J., Barvencik, F., Jakob, F., Hofbauer, L. C., Mundlos, S., Kornak, U., Seefried, L. & Oheim, R., 06.2021, In: BONE. 147, 115911.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. In Vivo Analysis of the Biocompatibility and Bone Healing Capacity of a Novel Bone Grafting Material Combined with Hyaluronic Acid

    Pröhl, A., Batinic, M., Alkildani, S., Hahn, M., Radenkovic, M., Najman, S., Jung, O. & Barbeck, M., 01.05.2021, In: INT J MOL SCI. 22, 9, 4818.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Bilateral Looser zones or pseudofractures in the anteromedial tibia as a component of medial tibial stress syndrome in athletes

    Stürznickel, J., Jandl, N. M., Delsmann, M. M., von Vopelius, E., Barvencik, F., Amling, M., Ueblacker, P., Rolvien, T. & Oheim, R., 05.2021, In: KNEE SURG SPORT TR A. 29, 5, p. 1644-1650 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Response of the ENPP1-deficient skeletal phenotype to oral phosphate supplementation and/or enzyme replacement therapy: Comparative studies in Humans and Mice

    Ferreira, C. R., Kavanagh, D., Oheim, R., Zimmerman, K., Stürznickel, J., Li, X., Stabach, P., Rettig, R. L., Calderone, L., MacKichan, C., Wang, A., Hutchinson, H. A., Nelson, T., Tommassini, S. M., von Kroge, S., Fiedler, I. A. K., Lester, E. R., Moeckel, G. W., Busse, B., Schinke, T., Carpenter, T. O., Levine, M. A., Horwowitz, M. C. & Braddock, D. T., 05.2021, In: J BONE MINER RES. 36, 5, p. 942-955 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. TFEB-deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality

    Sass, F., Schlein, C., Jaeckstein, M. Y., Pertzborn, P., Schweizer, M., Schinke, T., Ballabio, A., Scheja, L., Heeren, J. & Fischer, A. W., 05.2021, In: MOL METAB. 47, p. 101173

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Neurofibromatosis Type 1 With Cherubism-like Phenotype, Multiple Osteolytic Bone Lesions of Lower Extremities, and Alagille-syndrome: Case Report With Literature Survey

    Friedrich, R. E., Zustin, J., Luebke, A. M., Rosenbaum, T., Gosau, M., Hagel, C., Kohlrusch, F. K., Wieland, I. & Zenker, M., 30.04.2021, In: IN VIVO. 35, 3, p. 1711-1736 26 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Variability in stem taper surface topography affects the degree of corrosion and fretting in total hip arthroplasty

    Stockhausen, K. E., Riedel, C., Belinski, A. V., Rothe, D., Gehrke, T., Klebig, F., Gebauer, M., Amling, M., Citak, M. & Busse, B., 30.04.2021, In: SCI REP-UK. 11, 1, p. 9348

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Silk Fiber-Reinforced Hyaluronic Acid-Based Hydrogel for Cartilage Tissue Engineering

    Weitkamp, J-T., Wöltje, M., Nußpickel, B., Schmidt, F. N., Aibibu, D., Bayer, A., Eglin, D., Armiento, A. R., Arnold, P., Cherif, C., Lucius, R., Smeets, R., Kurz, B. & Behrendt, P., 31.03.2021, In: INT J MOL SCI. 22, 7, 3635.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Weightbearing Computed Tomography as a Novel Imaging Modality: Assessment of Peritalar Instability

    Schlickewei, C., Steadman, J., Stürznickel, J., Krähenbühl, N., Frosch, K-H. & International WBCT Society, 28.03.2021, In: Fuß & Sprunggelenk. p. 2-10 9 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  41. Safety and performance of biodegradable magnesium-based implants in children and adolescents

    Stürznickel, J., Delsmann, M. M., Jungesblut, O., Stücker, R., Knorr, C., Rolvien, T., Kertai, M. & Rupprecht, M., 15.03.2021, In: INJURY. 52, 8, p. 2265-2271

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Genotype-Phenotype Associations in 72 Adults with Suspected ALPL-Associated Hypophosphatasia

    Jandl, N. M., Schmidt, T., Rolvien, T., Stürznickel, J., Chrysostomou, K., von Vopelius, E., Volk, A. E., Schinke, T., Kubisch, C., Amling, M. & Barvencik, F., 03.2021, In: CALCIFIED TISSUE INT. 108, 3, p. 288-301 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Is hematopoietic stem cell transplantation a therapeutic option for mucolipidosis type II?

    Ammer, L. S., Pohl, S., Breyer, S. R., Aries, C., Denecke, J., Perez, A., Petzoldt, M., Schrum, J., Müller, I. & Muschol, N. M., 03.2021, In: MOL GENET METAB REP. 26, 100704.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Skeletal Biology and Disease Modeling in Zebrafish

    Dietrich, K., Fiedler, I. AK., Kurzyukova, A., López-Delgado, A. C., McGowan, L. M., Geurtzen, K., Hammond, C. L., Busse, B. & Knopf, F., 03.2021, In: J BONE MINER RES. 36, 3, p. 436-458 23 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  45. Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis

    Hinz, N., Baranowsky, A., Horn, M., Kriegs, M., Sibbertsen, F., Smit, D. J., Clezardin, P., Lange, T., Schinke, T. & Jücker, M., 18.02.2021, In: CELLS-BASEL. 10, 2, 430.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers

    Zwirner, J., Safavi, S., Scholze, M., Li, K. C., Waddell, J. N., Busse, B., Ondruschka, B. & Hammer, N., 12.02.2021, In: SCI REP-UK. 11, 1, 3721.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Bone mineral density assessment by DXA in rheumatic patients with end-stage osteoarthritis undergoing total joint arthroplasty

    Mühlenfeld, M., Strahl, A., Bechler, U., Jandl, N. M., Hubert, J. & Rolvien, T., 11.02.2021, In: BMC MUSCULOSKEL DIS. 22, 1, p. 173

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Transgenic inhibition of interleukin-6 trans-signaling does not prevent skeletal pathologies in mucolipidosis type II mice

    Westermann, L. M., Baranowsky, A., Di Lorenzo, G., Danyukova, T., Soul, J., Schwartz, J-M., Hendrickx, G., Amling, M., Rose-John, S., Garbers, C., Schinke, T. & Pohl, S., 11.02.2021, In: SCI REP-UK. 11, 1, p. 3556

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Bone healing and reactivation of remodeling under asfotase alfa therapy in adult patients with pediatric-onset hypophosphatasia

    Stürznickel, J., Schmidt, F. N., von Vopelius, E., Delsmann, M. M., Schmidt, C., Jandl, N. M., Oheim, R. & Barvencik, F., 02.2021, In: BONE. 143, p. 115794

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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