Department of Osteology and Biomechanics
Publications
- 2021
Clinical Phenotype and Relevance of LRP5 and LRP6 Variants in Patients With Early-Onset Osteoporosis (EOOP)
Stürznickel, J., Rolvien, T., Delsmann, A., Butscheidt, S., Barvencik, F., Mundlos, S., Schinke, T., Kornak, U., Amling, M. & Oheim, R., 02.2021, In: J BONE MINER RES. 36, 2, p. 271-282 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High-throughput lossy-to-lossless 3D image compression
Rossinelli, D., Fourestey, G., Schmidt, F., Busse, B. & Kurtcuoglu, V., 02.2021, In: IEEE T MED IMAGING. 40, 2, p. 607-620 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation
Hendrickx, G., Fischer, V., Liedert, A., von Kroge, S., Haffner-Luntzer, M., Brylka, L., Pawlus, E., Schweizer, M., Yorgan, T. A., Baranowsky, A., Rolvien, T., Neven, M., Schumacher, U., Beech, D. J., Amling, M., Ignatius, A. & Schinke, T., 02.2021, In: J BONE MINER RES. 36, 2, p. 369-384 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of c-Fos in orthodontic tooth movement: an in vivo study using transgenic mice
Decker, M. G., Nottmeier, C., Luther, J., Baranowsky, A., Kahl-Nieke, B., Amling, M., Schinke, T., David, J-P. & Koehne, T., 02.2021, In: CLIN ORAL INVEST. 25, 2, p. 593-601 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevance of Notch Signaling for Bone Metabolism and Regeneration
Ballhause, T. M., Jiang, S., Baranowsky, A., Brandt, S., Mertens, P. R., Frosch, K-H., Yorgan, T. & Keller, J., 29.01.2021, In: INT J MOL SCI. 22, 3Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Collagen Fiber Orientation Is Coupled with Specific Nano-Compositional Patterns in Dark and Bright Osteons Modulating Their Biomechanical Properties
Stockhausen, K. E., Qwamizadeh, M., Wölfel, E. M., Hemmatian, H., Fiedler, I. A. K., Flenner, S., Longo, E., Amling, M., Greving, I., Ritchie, R. O., Schmidt, F. N. & Busse, B., 26.01.2021, In: ACS NANO. 15, 1, p. 455-467 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Temporomandibular Joint Osteoarthritis: Regenerative Treatment by a Stem Cell Containing Advanced Therapy Medicinal Product (ATMP)-An In Vivo Animal Trial
Köhnke, R., Ahlers, M. O., Birkelbach, M. A., Ewald, F., Krueger, M., Fiedler, I., Busse, B., Heiland, M., Vollkommer, T., Gosau, M., Smeets, R. & Rutkowski, R., 05.01.2021, In: INT J MOL SCI. 22, 1, 443.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Procalcitonin Exerts a Mediator Role in Septic Shock Through the Calcitonin Gene-Related Peptide Receptor
Baranowsky, A., Appelt, J., Kleber, C., Lange, T., Ludewig, P., Jahn, D., Pandey, P., Keller, D., Rose, T., Schetler, D., Braumüller, S., Huber-Lang, M., Tsitsilonis, S., Yorgan, T. A., Frosch, K-H., Amling, M., Schinke, T. & Keller, J., 01.01.2021, In: CRIT CARE MED. 49, 1, p. e41-e52Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Breaking new ground in mineralized tissue: Assessing tissue quality in clinical and laboratory studies
Zimmermann, E. A., Fiedler, I. A. K. & Busse, B., 01.2021, In: J MECH BEHAV BIOMED. 113, 104138.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intraossäres Hibernom der Lendenwirbelsäule
Rolvien, T., Stürznickel, J., Klatte, T. O. & Zustin, J., 01.2021, In: ROFO-FORTSCHR RONTG. 193, 1, p. 80-82 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Bone Phenotyping Approaches in Human, Mice and Zebrafish - Expert Overview of the EU Cost Action GEMSTONE ("GEnomics of MusculoSkeletal traits TranslatiOnal NEtwork")
Foessl, I., Bassett, J. H. D., Bjørnerem, Å., Busse, B., Calado, Â., Chavassieux, P., Christou, M., Douni, E., Fiedler, I. A. K., Fonseca, J. E., Hassler, E., Högler, W., Kague, E., Karasik, D., Khashayar, P., Langdahl, B. L., Leitch, V. D., Lopes, P., Markozannes, G., McGuigan, F. E. A., Medina-Gomez, C., Ntzani, E., Oei, L., Ohlsson, C., Szulc, P., Tobias, J. H., Trajanoska, K., Tuzun, Ş., Valjevac, A., van Rietbergen, B., Williams, G. R., Zekic, T., Rivadeneira, F. & Obermayer-Pietsch, B., 2021, In: FRONT ENDOCRINOL. 12, 720728.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Ein Airbag kann auch tödlich sein
Hahn, M., Dreimann, M., Matschke, J., Lohner, L. & Püschel, K., 2021, In: RECHTSMEDIZIN.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
NEUE UND INNOVATIVE BIOMATERIALIEN, TECHNIKEN UND THERAPIEKONZEPTE
Smeets, R., Henningsen, A., Zernial, O., Stürmer, E. K., Fiedler, I. A. K., Wolff, J., Schäfer, S., Vollkommer, T., Gosau, M., Stolzer, C. & Fuest, S., 2021, In: Die zahnärztliche Praxis. 2021, 11/12 2020, p. 8-16Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Osteoblast-specific inactivation of p53 results in locally increased bone formation
Liao, N., Koehne, T., Tuckermann, J., Triviai, I., Amling, M., David, J-P., Schinke, T. & Luther, J., 2021, In: PLOS ONE. 16, 11, p. e0249894Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Perspective of the GEMSTONE Consortium on Current and Future Approaches to Functional Validation for Skeletal Genetic Disease Using Cellular, Molecular and Animal-Modeling Techniques
Rauner, M., Foessl, I., Formosa, M. M., Kague, E., Prijatelj, V., Lopez, N. A., Banerjee, B., Bergen, D., Busse, B., Calado, Â., Douni, E., Gabet, Y., Giralt, N. G., Grinberg, D., Lovsin, N. M., Solan, X. N., Ostanek, B., Pavlos, N. J., Rivadeneira, F., Soldatovic, I., van de Peppel, J., van der Eerden, B., van Hul, W., Balcells, S., Marc, J., Reppe, S., Søe, K. & Karasik, D., 2021, In: FRONT ENDOCRINOL. 12, 731217.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2020
Accelerated tooth movement in Rsk2-deficient mice with impaired cementum formation
Nottmeier, C., Decker, M. G., Luther, J., von Kroge, S., Kahl-Nieke, B., Amling, M., Schinke, T., Petersen, J. & Koehne, T., 23.12.2020, In: INT J ORAL SCI. 12, 1, p. 35Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma
Westermann, L. M., Fleischhauer, L., Vogel, J., Jenei-Lanzl, Z., Floriano Ludwig, N., Schau, L., Morellini, F., Baranowsky, A., Yorgan, T. A., Di Lorenzo, G., Schweizer, M., de Souza Pinheiro, B., Guarany, N. R., Sperb-Ludwig, F., Visioli, F., Oliveira Silva, T., Soul, J., Hendrickx, G., Wiegert, J. S., Schwartz, I. V. D., Clausen-Schaumann, H., Zaucke, F., Schinke, T., Pohl, S. & Danyukova, T., 18.11.2020, In: DIS MODEL MECH. 13, 11Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Age-related changes of micro-morphological subchondral bone properties in the healthy femoral head
Ries, C., Boese, C. K., Stürznickel, J., Koehne, T., Hubert, J., Pastor, M-F., Hahn, M., Meier, S. L., Beil, F. T., Püschel, K., Amling, M. & Rolvien, T., 11.2020, In: OSTEOARTHR CARTILAGE. 28, 11, p. 1437-1447 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Individuals with type 2 diabetes mellitus show dimorphic and heterogeneous patterns of loss in femoral bone quality
Wölfel, E. M., Jähn-Rickert, K., Schmidt, F. N., Wulff, B., Mushumba, H., Sroga, G. E., Püschel, K., Milovanovic, P., Amling, M., Campbell, G. M., Vashishth, D. & Busse, B., 11.2020, In: BONE. 140, p. 115556Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting of δ-catenin to postsynaptic sites through interaction with the Shank3 N-terminus
Hassani Nia, F., Woike, D., Martens, V., Klüssendorf, M., Hönck, H-H., Harder, S. & Kreienkamp, H-J., 28.10.2020, In: MOL AUTISM. 11, 1, p. 85Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Analysis of low-dose estrogen on callus BMD as measured by pQCT in postmenopausal women
Jäckle, K., Kolb, J. P., Schilling, A. F., Schlickewei, C., Amling, M., Rueger, J. M. & Lehmann, W., 19.10.2020, In: BMC MUSCULOSKEL DIS. 21, 1, p. 693Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Warmth Prevents Bone Loss Through the Gut Microbiota
Chevalier, C., Kieser, S., Çolakoğlu, M., Hadadi, N., Brun, J., Rigo, D., Suárez-Zamorano, N., Spiljar, M., Fabbiano, S., Busse, B., Ivanišević, J., Macpherson, A., Bonnet, N. & Trajkovski, M., 06.10.2020, In: CELL METAB. 32, 4, p. 575-590.e7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cartilage calcification is associated with histological degeneration of the knee joint: a highly prevalent, age-independent systemic process
Hubert, J., Beil, F. T., Rolvien, T., Butscheidt, S., Hischke, S., Püschel, K., Frosch, S., Mussawy, H., Ries, C. & Hawellek, T., 10.2020, In: OSTEOARTHR CARTILAGE. 28, 10, p. 1351-1361 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Variation in skull bone mineral density of ringed seals (Phoca hispida) from the Gulf of Bothnia and West Greenland between 1829 and 2019
Schmidt, B., Sonne, C., Nachtsheim, D., Dietz, R., Oheim, R., Rolvien, T., Persson, S., Amling, M. & Siebert, U., 10.2020, In: ENVIRON INT. 143, p. 105968Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In Vitro Feasibility Analysis of a New Sutureless Wound-Closure System Based on a Temperature-Regulated Laser and a Transparent Collagen Membrane for Laser Tissue Soldering (LTS)
Birkelbach, M. A., Smeets, R., Fiedler, I., Kluwe, L., Wehner, M., Trebst, T. & Hartjen, P., 26.09.2020, In: INT J MOL SCI. 21, 19Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Arylsulfatase K inactivation causes mucopolysaccharidosis due to deficient glucuronate desulfation of heparan and chondroitin sulfate
Trabszo, C., Ramms, B., Chopra, P., Lüllmann-Rauch, R., Stroobants, S., Sproß, J., Jeschke, A., Schinke, T., Boons, G-J., Esko, J. D., Lübke, T. & Dierks, T., 18.09.2020, In: BIOCHEM J. 477, 17, p. 3433-3451 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel, multi-level approach to assess allograft incorporation in revision total hip arthroplasty
Rolvien, T., Friesecke, C., Butscheidt, S., Gehrke, T., Hahn, M. & Püschel, K., 16.09.2020, In: SCI REP-UK. 10, 1, p. 15226Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ablation Precision and Thermal Effects of a Picosecond Infrared Laser (PIRL) on Roots of Human Teeth: A Pilot Study Ex Vivo
Friedrich, R. E., Quade, M., Jowett, N., Kroetz, P., Amling, M., Kohlrusch, F. K., Zustin, J., Gosau, M., SchlÜter, H. & Miller, R. J. D., 03.09.2020, In: IN VIVO. 34, 5, p. 2325-2336 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fgfr3 Is a Positive Regulator of Osteoblast Expansion and Differentiation During Zebrafish Skull Vault Development
Dambroise, E., Ktorza, I., Brombin, A., Abdessalem, G., Edouard, J., Luka, M., Fiedler, I., Binder, O., Pelle, O., Patton, E. E., Busse, B., Menager, M., Sohm, F. & Legeai-Mallet, L., 09.2020, In: J BONE MINER RES. 35, 9, p. 1782-1797 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mice carrying a ubiquitous R235W mutation of Wnt1 display a bone-specific phenotype
Yorgan, T., Rolvien, T., Stürznickel, J., Vollersen, N., Lange, F., Zhao, W., Baranowsky, A., Rosenthal, L., Hermans-Borgmeyer, I., Sharaf, A., Karsak, M., David, J-P., Oheim, R., Amling, M. & Schinke, T., 09.2020, In: J BONE MINER RES. 35, 9, p. 1726-1737 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The neuropeptide calcitonin gene-related peptide alpha is essential for bone healing
Appelt, J., Baranowsky, A., Jahn, D., Yorgan, T. A., Köhli, P., Otto, E., Farahani, S. K., Graef, F., Fuchs, M., Herrera, A., Amling, M., Schinke, T., Frosch, K-H., Duda, G. N., Tsitsilonis, S. & Keller, J., 09.2020, In: EBIOMEDICINE. 59, p. 102970Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Whole-Exome Sequencing Identifies Novel Compound Heterozygous ZNF469 Mutations in Two Siblings with Mild Brittle Cornea Syndrome
Rolvien, T., Kornak, U., Linke, S. J., Amling, M. & Oheim, R., 09.2020, In: CALCIFIED TISSUE INT. 107, 3, p. 294-299 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype
Tonelli, F., Cotti, S., Leoni, L., Besio, R., Gioia, R., Marchese, L., Giorgetti, S., Villani, S., Gistelinck, C., Wagener, R., Kobbe, B., Fiedler, I., Larionova, D., Busse, B., Eyre, D., Rossi, A., Witten, P. E. & Forlino, A., 08.2020, In: MATRIX BIOL. 90, p. 40-60 21 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disruption of the hepcidin/ferroportin regulatory circuitry causes low axial bone mass in mice
Ledesma-Colunga, M. G., Baschant, U., Fiedler, I. A. K., Busse, B., Hofbauer, L. C., Muckenthaler, M. U., Altamura, S. & Rauner, M., 08.2020, In: BONE. 137, p. 115400Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distinct modes of balancing glomerular cell proteostasis in mucolipidosis type II and III prevent proteinuria
Sachs, W., Sachs, M., Krüger, E., Zielinski, S., Kretz, O., Huber, T., Baranowsky, A., Westermann, L. M., Voltolini Velho, R., Floriano Ludwig, N., Yorgan, T. A., Di Lorenzo, G., Kollmann, K., Braulke, T., Schwartz, I. V. D., Schinke, T., Danyukova, T., Pohl, S. & Meyer-Schwesinger, C., 08.2020, In: J AM SOC NEPHROL. 31, 8, p. 1796-1814 19 p., 31(8).Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effect of variations in tissue-level ductility on human vertebral strength
Sadoughi, S., Vom Scheidt, A., Nawathe, S., Zhu, S., Moini, A. & Keaveny, T. M., 08.2020, In: BONE. 137, p. 115445Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatocyte growth factor and matrix metalloprotease 2 levels in synovial fluid of the knee joint are correlated with clinical outcome of meniscal repair
Mull, C., Wohlmuth, P., Krause, M., Alm, L., Kling, H., Schilling, A. F. & Frosch, K-H., 08.2020, In: KNEE. 27, 4, p. 1143-1150 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary intraosseous meningioma: clinical, histological, and differential diagnostic aspects
Butscheidt, S., Ernst, M., Rolvien, T., Hubert, J., Zustin, J., Amling, M. & Martens, T., 08.2020, In: J NEUROSURG. 133, 2, p. 451–461 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
More Bone with Less Minerals? The Effects of Dietary Phosphorus on the Post-Cranial Skeleton in Zebrafish
Cotti, S., Huysseune, A., Koppe, W., Rücklin, M., Marone, F., Wölfel, E. M., Fiedler, I. A. K., Busse, B., Forlino, A. & Witten, P. E., 30.07.2020, In: INT J MOL SCI. 21, 15Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ALCAM contributes to brain metastasis formation in non-small-cell lung cancer through interaction with the vascular endothelium
Münsterberg, J., Loreth, D., Brylka, L., Werner, S., Karbanova, J., Gandrass, M., Schneegans, S., Besler, K., Hamester, F., Robador, J. R., Bauer, A. T., Werner Schneider, S., Wrage, M., Lamszus, K., Matschke, J., Vashist, Y., Uzunoglu, G., Steurer, S., Horst, A. K., Oliveira-Ferrer, L., Glatzel, M., Schinke, T., Corbeil, D., Pantel, K., Maire, C. & Wikman, H., 07.07.2020, In: NEURO-ONCOLOGY. 22, 7, p. 955-966 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Radiological and Histopathological Features of Internal Tooth Resorption
Koehne, T., Zustin, J., Amling, M. & Friedrich, R. E., 02.07.2020, In: IN VIVO. 34, 4, p. 1875-1882 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adult osteosclerotic metaphyseal dysplasia with progressive osteonecrosis of the jaws and abnormal bone resorption pattern due to a LRRK1 splice site mutation
Howaldt, A., Hennig, A. F., Rolvien, T., Rössler, U., Stelzer, N., Knaus, A., Böttger, S., Zustin, J., Geißler, S., Oheim, R., Amling, M., Howaldt, H-P. & Kornak, U., 07.2020, In: J BONE MINER RES. 35, 7, p. 1322-1332 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-term immobilization in elderly females causes a specific pattern of cortical bone and osteocyte deterioration different from postmenopausal osteoporosis
Rolvien, T., Milovanovic, P., Schmidt, F. N., von Kroge, S., Wölfel, E. M., Krause, M., Wulff, B., Püschel, K., Ritchie, R. O., Amling, M. & Busse, B., 07.2020, In: J BONE MINER RES. 35, 7, p. 1343-1351 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gnathodiaphyseal dysplasia is not recapitulated in a respective mouse model carrying a mutation of the Ano5 gene
Rolvien, T., Avci, O., von Kroge, S., Koehne, T., Selbert, S., Sonntag, S., Shmerling, D., Kornak, U., Oheim, R., Amling, M., Schinke, T. & Yorgan, T. A., 06.2020, In: BONE REP. 12, p. 100281Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Large osteocyte lacunae in iliac crest infantile bone are not associated with impaired mineral distribution or signs of osteocytic osteolysis
Jandl, N. M., von Kroge, S., Stürznickel, J., Baranowsky, A., Stockhausen, K. E., Mushumba, H., Beil, F. T., Püschel, K., Amling, M. & Rolvien, T., 06.2020, In: BONE. 135, p. 115324Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Numerical study of crack initiation and growth in human cortical bone: Effect of micro-morphology
Wang, M., Li, S., Scheidt, A. V., Qwamizadeh, M., Busse, B. & Silberschmidt, V. V., 06.2020, In: ENG FRACT MECH. 232, 107051.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Symptomatic Intraosseous Vascular Malformation of Infraorbital Rim: A Case Report With Literature Survey
Friedrich, R. E., Grzyska, U., Kohlrusch, F. K., VON Kroge, S., Vollkommer, T. & Luebke, A. M., 06.2020, In: ANTICANCER RES. 40, 6, p. 3333-3343 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impaired Bone Microarchitecture in Patients with Hereditary Hemochromatosis and Skeletal Complications
Jandl, N. M., Rolvien, T., Schmidt, T., Mussawy, H., Nielsen, P., Oheim, R., Amling, M. & Barvencik, F., 05.2020, In: CALCIFIED TISSUE INT. 106, 5, p. 465-475 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Zebrafish: An Emerging Model for Orthopedic Research
Busse, B., Galloway, J. L., Gray, R. S., Harris, M. P. & Kwon, R. Y., 05.2020, In: J ORTHOP RES. 38, 5, p. 925-936 12 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Phenomenon of osteocyte lacunar mineralization: indicator of former osteocyte death and a novel marker of impaired bone quality?
Milovanovic, P. & Busse, B., 04.2020, In: ENDOCR CONNECT. 9, 4, p. R70-R80 11 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research