Department of Osteology and Biomechanics
Publications
- 2024
Patient experiences of interprofessional collaboration and intersectoral communication in rare disease healthcare in Germany - a mixed-methods study
Inhestern, L., Otto, R., Brandt, M., Zybarth, D., Oheim, R., Schüler, H., Mir, T. S., Tsiakas, K., Dibaj, P., Zschüntzsch, J., Okun, P. M., Hegenbart, U., Sommerburg, O., Schramm, C., Weiler-Normann, C., Härter, M. & Bergelt, C., 13.05.2024, In: ORPHANET J RARE DIS. 19, 1, p. 197Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Alterations in compositional and cellular properties of the subchondral bone are linked to cartilage degeneration in hip osteoarthritis
Delsmann, J., Eissele, J., Simon, A., Alimy, A-R., von Kroge, S., Mushumba, H., Püschel, K., Busse, B., Ries, C., Amling, M., Beil, F. T. & Rolvien, T., 05.2024, In: OSTEOARTHR CARTILAGE. 32, 5, p. 535-547 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hereditary hypophosphatemic rickets with hypercalciuria (HHRH), a complex disorder in need of precision medicine
Schinke, T. & Oheim, R., 05.2024, In: KIDNEY INT. 105, 5, p. 927-929 3 p.Research output: SCORING: Contribution to journal › Comment/debate › Research
Pronounced cortical porosity and sex-specific patterns of increased bone and osteocyte lacunar mineralization characterize the human distal fibula with aging
Hering, R-N., von Kroge, S., Delsmann, J., Simon, A., Ondruschka, B., Püschel, K., Schmidt, F. N. & Rolvien, T., 05.2024, In: BONE. 182, p. 117068Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased β2-adrenergic signaling promotes fracture healing through callus neovascularization in mice
Jahn, D., Knapstein, P. R., Otto, E., Köhli, P., Sevecke, J., Graef, F., Graffmann, C., Fuchs, M., Jiang, S., Rickert, M., Erdmann, C., Appelt, J., Revend, L., Küttner, Q., Witte, J., Rahmani, A., Duda, G., Xie, W., Donat, A., Schinke, T., Ivanov, A., Tchouto, M. N., Beule, D., Frosch, K-H., Baranowsky, A., Tsitsilonis, S. & Keller, J., 17.04.2024, In: SCI TRANSL MED. 16, 743, p. eadk9129Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional analysis of postural spinal and pelvic parameters using static and dynamic spinometry
Bode, T., Zoroofchi, S., Vettorazzi, E., Droste, J-N., Welsch, G. H., Schwesig, R. & Marshall, R. P., 15.04.2024, In: HELIYON. 10, 7, p. e29239Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lower microhardness along with less heterogeneous mineralization in the femoral neck of individuals with type 2 diabetes mellitus indicates higher fracture risk
Cirovic, A., Schmidt, F. N., Vujacic, M., Sihota, P., Petrovic, B., Zivkovic, V., Bascarevic, Z., Nikolic, S., Djonic, D., Djuric, M., Busse, B. & Milovanovic, P., 03.2024, In: JBMR PLUS. 8, 3, p. ziae005Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lysosomal enzyme trafficking: from molecular mechanisms to human diseases
Braulke, T., Carette, J. E. & Palm, W., 03.2024, In: TRENDS CELL BIOL. 34, 3, p. 198-210 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Mechanical induction of osteoanabolic Wnt1 promotes osteoblast differentiation via Plat
Ahmad, M., Haffner-Luntzer, M., Schoppa, A., Najafova, Z., Lukic, T., Yorgan, T. A., Amling, M., Schinke, T. & Ignatius, A., 29.02.2024, In: FASEB J. 38, 4, e23489.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development
Brylka, L. J., Alimy, A-R., Tschaffon-Müller, M. E. A., Jiang, S., Ballhause, T. M., Baranowsky, A., von Kroge, S., Delsmann, J., Pawlus, E., Eghbalian, K., Püschel, K., Schoppa, A., Haffner-Luntzer, M., Beech, D. J., Beil, F. T., Amling, M., Keller, J., Ignatius, A., Yorgan, T. A., Rolvien, T. & Schinke, T., 23.02.2024, In: BONE RES. 12, 1, p. 12Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Age-related changes in the midpalatal suture: Comparison between CBCT staging and bone micromorphology
Georgi, G. M., Knauth, S., Hirsch, E., Schulz-Kornas, E., Kahl-Nieke, B., Püschel, K., Amling, M., Koehne, T., Korbmacher-Steiner, H. & Petersen, J., 02.2024, In: BONE. 179, 116984.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling
Hendrickx, G., Boudin, E., Mateiu, L., Yorgan, T. A., Steenackers, E., Kneissel, M., Kramer, I., Mortier, G., Schinke, T. & Van Hul, W., 02.2024, In: CALCIFIED TISSUE INT. 114, 2, p. 171-181 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bisphosphonate Use and Periprosthetic Fractures
Alimy, A-R., Beil, F. T., Amling, M. & Rolvien, T., 01.2024, In: J ARTHROPLASTY. 39, 1, p. e1-e2Research output: SCORING: Contribution to journal › Letter › Research › peer-review
- 2023
Cholesteatoma Severely Impacts the Integrity and Bone Material Quality of the Incus
Delsmann, M. M., Bonik, P., Ocokoljic, A., Häussler, S. M., Püschel, K., Praetorius, M., Amling, M., Peichl, J. & Rolvien, T., 12.2023, In: CALCIFIED TISSUE INT. 113, 6, p. 609-617 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of Motion Grading in 1,000 Patients by First- and Second-Generation HR-pQCT: A Propensity Score Matched Cohort Study
Bartosik, M., Simon, A., Strahl, A., Oheim, R., Amling, M. & Schmidt, F. N., 12.2023, In: CALCIFIED TISSUE INT. 113, 6, p. 597-608 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epidemiology of Tumor-Induced Osteomalacia in Germany Based on Real World Data
May, M., Oheim, R., Bovy, L., Doess, A., Maessen, D., Neukirch, B., Norris, R., Williams, A. & Abrahamsen, B., 12.2023, In: CALCIFIED TISSUE INT. 113, 6, p. 630-639 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage
Danyukova, T., Alimy, A-R., Velho, R. V., Yorgan, T. A., Di Lorenzo, G., von Kroge, S., Tidow, H., Wiegert, J. S., Hermans-Borgmeyer, I., Schinke, T., Rolvien, T. & Pohl, S., 12.2023, In: BONE. 177, 116927.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Micropetrosis: Osteocyte Lacunar Mineralization in Aging and Disease
Milovanovic, P. & Busse, B., 12.2023, In: CURR OSTEOPOROS REP. 21, 6, p. 750-757 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Utility and Limitations of TALLYHO/JngJ as a Model for Type 2 Diabetes-Induced Bone Disease
Emini, L., Salbach-Hirsch, J., Krug, J., Jähn-Rickert, K., Busse, B., Rauner, M. & Hofbauer, L. C., 12.2023, In: JBMR PLUS. 7, 12, e10843.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
When Cortical Bone Matrix Properties Are Indiscernible between Elderly Men with and without Type 2 Diabetes, Fracture Resistance Follows Suit
Wölfel, E. M., Bartsch, B., Koldehoff, J., Fiedler, I. A. K., Dragoun-Kolibova, S., Schmidt, F. N., Krug, J., Lin, M-C., Püschel, K., Ondruschka, B., Zimmermann, E. A., Jelitto, H., Schneider, G., Gludovatz, B. & Busse, B., 12.2023, In: JBMR PLUS. 7, 12, p. e10839Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Empfehlungen zur Versorgung von Patient:innen mit FOP
Seefried, L., Banholzer, D., Fischer, R., Grafe, I., Hüning, I., Morhart, R., Oheim, R., Semler, O., Siggelkow, H., Stockklausner, C. & Hoyer-Kuhn, H., 11.2023, In: ORTHOPADIE. 52, 11, p. 924-930 7 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Fractal analysis of the mandible cortical bone: correlation among fractal dimension values obtained by two processing methods from periapical radiograph and micro-computed tomography with cone-beam computed tomography
de Oliveira Loures, A., de Abreu, M., Devito, K. L., Grisolia-Seifert, E. F., Jähn-Rickert, K. & Rabelo, G. D., 11.2023, In: RADIAT ENVIRON BIOPH. 62, 4, p. 511-518 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The selective norepinephrine reuptake inhibitor reboxetine promotes late-stage fracture healing in mice
Donat, A., Jiang, S., Xie, W., Knapstein, P. R., Albertsen, L-C., Kokot, J. L., Sevecke, J., Augustin, R., Jahn, D., Yorgan, T. A., Frosch, K-H., Tsitsilonis, S., Baranowsky, A. & Keller, J., 20.10.2023, In: ISCIENCE. 26, 10, 107761.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease
Mellor, L. F., Gago-Lopez, N., Bakiri, L., Schmidt, F. N., Busse, B., Rauber, S., Jimenez, M., Megías, D., Oterino-Soto, S., Sanchez-Prieto, R., Grivennikov, S., Pu, X., Oxford, J., Ramming, A., Schett, G. & Wagner, E. F., 18.10.2023, In: ANN RHEUM DIS. 81, 10, p. 1400-1408 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Do Clinical Parameters Reflect Local Bone Metabolism in Heterotopic Ossification After Septic or Aseptic THA?
von Kroge, S., Büyükyilmaz, Z., Alimy, A-R., Hubert, J., Citak, M., Amling, M., Beil, F. T., Ohlmeier, M. & Rolvien, T., 01.10.2023, In: CLIN ORTHOP RELAT R. 481, 10, p. 2029-2041 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Zinc and vitamin D deficiency and supplementation in hypophosphatasia patients: A retrospective study
Wiedemann, P., Schmidt, F. N., Amling, M., Yorgan, T. A. & Barvencik, F., 10.2023, In: BONE. 175, 116849.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
AXIN1 bi-allelic variants disrupting the C-terminal DIX domain cause craniometadiaphyseal osteosclerosis with hip dysplasia
Terhal, P., Venhuizen, A. J., Lessel, D., Tan, W-H., Alswaid, A., Grün, R., Alzaidan, H. I., von Kroge, S., Ragab, N., Hempel, M., Kubisch, C., Novais, E., Cristobal, A., Tripolszki, K., Bauer, P., Fischer-Zirnsak, B., Nievelstein, R. A. J., van Dijk, A., Nikkels, P., Oheim, R., Hahn, H., Bertoli-Avella, A., Maurice, M. M. & Kornak, U., 07.09.2023, In: AM J HUM GENET. 110, 9, p. 1470-1481 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TMCO3, a Putative K+ :Proton Antiporter at the Golgi Apparatus, Is Important for Longitudinal Growth in Mice and Humans
Holling, T., Brylka, L. J., Scholz, T., Bierhals, T., Herget, T., Meinecke, P., Schinke, T., Oheim, R. & Kutsche, K., 09.2023, In: J BONE MINER RES. 38, 9, p. 1334-1349 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dynamics of Skeletal Status under Optimized Management during Subsequent Pregnancy in Three Women with a History of Pregnancy- and Lactation-Associated Osteoporosis Carrying pathogenic Variants in WNT1 and LRP5
Stürznickel, J., Butscheidt, S., Amling, M. & Oheim, R., 08.2023, In: JBMR PLUS. 7, 8, e10779.Research output: SCORING: Contribution to journal › Case report › Research › peer-review
Why animal experiments are still indispensable in bone research: A statement by the European Calcified Tissue Society
Stein, M., Elefteriou, F., Busse, B., Fiedler, I. A. K., Kwon, R. Y., Farell, E., Ahmad, M., Ignatius, A., Grover, L., Geris, L. & Tuckermann, J., 08.2023, In: J BONE MINER RES. 38, 8, p. 1045-1061 17 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Increased beta2-adrenergic signaling is a targetable stimulus essential for bone healing by promoting callus neovascularization
Jahn, D., Knapstein, P. R., Otto, E., Köhli, P., Sevecke, J., Graef, F., Graffmann, C., Fuchs, M., Jiang, S., Rickert, M., Erdmann, C., Appelt, J., Revend, L., Küttner, Q., Witte, J., Rahmani, A., Duda, G., Xie, W., Donat, A., Schinke, T., Ivanov, A., Tchouto, M. N., Beule, D., Frosch, K-H., Baranowsky, A., Tsitsilonis, S. & Keller, J., 16.07.2023, In: bioRxiv.Research output: SCORING: Contribution to journal › Preprint › Research
Fracture healing in a mouse model of Hajdu–Cheney-Syndrome with high turnover osteopenia results in decreased biomechanical stability
Ballhause, T. M., Jiang, S., Xie, W., Sevecke, J., Dowling, C., Dust, T., Brandt, S., Mertens, P. R., Yorgan, T. A., Schinke, T., Frosch, K-H., Baranowsky, A. & Keller, J., 14.07.2023, In: SCI REP-UK. 13, 1, p. 11418 11418.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CNS Manifestations in Mucolipidosis Type II-A Retrospective Analysis of Longitudinal Data on Neurocognitive Development and Neuroimaging in Eleven Patients
Ammer, L. S., Täuber, K., Perez, A., Dohrmann, T., Denecke, J., Santer, R., Blümlein, U., Ozga, A-K., Pohl, S. & Muschol, N. M., 18.06.2023, In: J CLIN MED. 12, 12, 4114.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mechanical-induced bone remodeling does not depend on Piezo1 in dentoalveolar hard tissue
Nottmeier, C., Lavicky, J., Gonzalez Lopez, M., Knauth, S., Kahl-Nieke, B., Amling, M., Schinke, T., Helms, J., Krivanek, J., Koehne, T. & Petersen, J., 12.06.2023, In: SCI REP-UK. 13, 1, 9563.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficacy of zoledronic acid for the elimination of disseminated tumor cells in a clinically relevant, spontaneously metastatic prostate cancer xenograft model
Böckelmann, L. C., Freytag, V., Ahlers, A-K., Maar, H., Gosau, T., Baranowsky, A., Schmitz, R., Pantel, K., Schumacher, U., Haider, M-T. & Lange, T., 06.2023, In: BONE. 171, p. 116741Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Radial HR-pQCT and Finite Element Analysis in HPP Patients are Superior in Identifying Susceptibility to Fracture-Associated Skeletal Affections Compared to DXA and Laboratory Tests
Schmidt, F. N., Schmidt, C., Delsmann, J., Amling, M. & Barvencik, F., 06.2023, In: CALCIFIED TISSUE INT. 112, 6, p. 691-703 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effects of more natural housing conditions on the muscular and skeletal characteristics of female C57BL/6J mice
Mieske, P., Scheinpflug, J., Yorgan, T. A., Brylka, L., Palme, R., Hobbiesiefken, U., Preikschat, J., Lewejohann, L. & Diederich, K., 16.05.2023, In: LAB ANIM RES. 39, 1, p. 9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone mineral density and microarchitecture change during skeletal growth in harbor seals (Phoca vitulina) from the German coast
Delsmann, J., Schmidt, B., Oheim, R., Amling, M., Rolvien, T. & Siebert, U., 03.05.2023, In: SCI REP-UK. 13, 1, 7196.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Analysis of Three-Dimensional Bone Microarchitecture of the Axis Exposes Pronounced Regional Heterogeneity Associated with Clinical Fracture Patterns
Koepke, L-G., Kroge, S. V., Heuer, A., Kammal, A. L., Ondruschka, B., Rolvien, T. & Viezens, L., 05.2023, In: CALCIFIED TISSUE INT. 112, 5, p. 563-572 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Osteocyte apoptosis and cellular micropetrosis signify skeletal aging in type 1 diabetes
Dragoun Kolibová, S., Wölfel, E. M., Hemmatian, H., Milovanovic, P., Mushumba, H., Wulff, B., Neidhardt, M., Püschel, K., Failla, A. V., Vlug, A., Schlaefer, A., Ondruschka, B., Amling, M., Hofbauer, L. C., Rauner, M., Busse, B. & Jähn-Rickert, K., 05.2023, In: ACTA BIOMATER. 162, p. 254-265 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Radiolucent zones of biodegradable magnesium-based screws in children and adolescents-a radiographic analysis
Delsmann, M. M., Stürznickel, J., Kertai, M., Stücker, R., Rolvien, T. & Rupprecht, M., 05.2023, In: ARCH ORTHOP TRAUM SU. 143, 5, p. 2297-2305 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Wnt1 Boosts Fracture Healing by Enhancing Bone Formation in the Fracture Callus
Haffner-Luntzer, M., Ragipoglu, D., Ahmad, M., Schoppa, A., Steppe, L., Fischer, V., Luther, J., Yorgan, T., Bockamp, E., Amling, M., Schinke, T. & Ignatius, A., 05.2023, In: J BONE MINER RES. 38, 5, p. 749-764 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis
Reichelt, J., Sachs, W., Frömbling, S., Fehlert, J., Studencka-Turski, M., Betz, A., Loreth, D., Blume, L., Witt, S., Pohl, S., Brand, J., Czesla, M., Knop, J., Florea, B. I., Zielinski, S., Sachs, M., Hoxha, E., Hermans-Borgmeyer, I., Zahner, G., Wiech, T., Krüger, E. & Meyer-Schwesinger, C., 13.04.2023, In: NAT COMMUN. 14, 1, p. 2114Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effects of Infantile Hypophosphatasia on Human Dental Tissue
Wölfel, E. M., von Kroge, S., Matthies, L., Köhne, T., Petz, K., Beikler, T., Schmid-Herrmann, C., Kahl-Nieke, B., Tsiakas, K., Santer, R., Muschol, N. M., Herrmann, J., Busse, B., Amling, M., Rolvien, T., Jandl, N. M. & Barvencik, F., 03.2023, In: CALCIFIED TISSUE INT. 112, 3, p. 308-319 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ex Vivo Model of Neuroblastoma Plasticity
Schäfer, P., Muhs, S., Turnbull, L., Garwal, P., Maar, H., Yorgan, T. A., Tolosa, E., Lange, T. & Windhorst, S., 17.02.2023, In: CANCERS. 15, 4, 1274.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Age-, sex- and subregion-specific properties of distal fibular microarchitecture and strength: an ex vivo HR-pQCT study
Schlickewei, C., Schweizer, C., Püschel, K., Ondruschka, B., Kleinertz, H., Barg, A., Rolvien, T. & Stürznickel, J., 02.2023, In: J ORTHOP RES. 41, 2, p. 355-363 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of polyethylene glenoid cementation technique on cement mantle integrity and stability after cyclic loading: a computed tomography and biomechanical study
Kasten, P., Jandl, N. M., Zeifang, F., Dallmann, F., Jakobs, S., Stalder, K. & Niemeier, A., 02.2023, In: J SHOULDER ELB SURG. 32, 2, p. 383-391 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Denosumab and muscle performance
Rolvien, T., Rupp, T., Strahl, A. & Amling, M., 01.2023, In: OSTEOPOROSIS INT. 34, 1, p. 211-212 2 p.Research output: SCORING: Contribution to journal › Letter › Research › peer-review
On the fracture behavior of cortical bone microstructure: The effects of morphology and material characteristics of bone structural components
Allahyari, P., Silani, M., Yaghoubi, V., Milovanovic, P., Schmidt, F. N., Busse, B. & Qwamizadeh, M., 01.2023, In: J MECH BEHAV BIOMED. 137, 105530.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reduced Bone Mass and Increased Osteocyte Tartrate-Resistant Acid Phosphatase (TRAP) Activity, But Not Low Mineralized Matrix Around Osteocyte Lacunae, Are Restored After Recovery From Exogenous Hyperthyroidism in Male Mice
Wölfel, E. M., Lademann, F., Hemmatian, H., Blouin, S., Messmer, P., Hofbauer, L. C., Busse, B., Rauner, M., Jähn-Rickert, K. & Tsourdi, E., 01.2023, In: J BONE MINER RES. 38, 1, p. 131-143 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review