Department of Osteology and Biomechanics

Publications

  1. 2024
  2. Patient experiences of interprofessional collaboration and intersectoral communication in rare disease healthcare in Germany - a mixed-methods study

    Inhestern, L., Otto, R., Brandt, M., Zybarth, D., Oheim, R., Schüler, H., Mir, T. S., Tsiakas, K., Dibaj, P., Zschüntzsch, J., Okun, P. M., Hegenbart, U., Sommerburg, O., Schramm, C., Weiler-Normann, C., Härter, M. & Bergelt, C., 13.05.2024, In: ORPHANET J RARE DIS. 19, 1, p. 197

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Alterations in compositional and cellular properties of the subchondral bone are linked to cartilage degeneration in hip osteoarthritis

    Delsmann, J., Eissele, J., Simon, A., Alimy, A-R., von Kroge, S., Mushumba, H., Püschel, K., Busse, B., Ries, C., Amling, M., Beil, F. T. & Rolvien, T., 05.2024, In: OSTEOARTHR CARTILAGE. 32, 5, p. 535-547 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Hereditary hypophosphatemic rickets with hypercalciuria (HHRH), a complex disorder in need of precision medicine

    Schinke, T. & Oheim, R., 05.2024, In: KIDNEY INT. 105, 5, p. 927-929 3 p.

    Research output: SCORING: Contribution to journalComment/debateResearch

  5. Pronounced cortical porosity and sex-specific patterns of increased bone and osteocyte lacunar mineralization characterize the human distal fibula with aging

    Hering, R-N., von Kroge, S., Delsmann, J., Simon, A., Ondruschka, B., Püschel, K., Schmidt, F. N. & Rolvien, T., 05.2024, In: BONE. 182, p. 117068

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Increased β2-adrenergic signaling promotes fracture healing through callus neovascularization in mice

    Jahn, D., Knapstein, P. R., Otto, E., Köhli, P., Sevecke, J., Graef, F., Graffmann, C., Fuchs, M., Jiang, S., Rickert, M., Erdmann, C., Appelt, J., Revend, L., Küttner, Q., Witte, J., Rahmani, A., Duda, G., Xie, W., Donat, A., Schinke, T., Ivanov, A., Tchouto, M. N., Beule, D., Frosch, K-H., Baranowsky, A., Tsitsilonis, S. & Keller, J., 17.04.2024, In: SCI TRANSL MED. 16, 743, p. eadk9129

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Functional analysis of postural spinal and pelvic parameters using static and dynamic spinometry

    Bode, T., Zoroofchi, S., Vettorazzi, E., Droste, J-N., Welsch, G. H., Schwesig, R. & Marshall, R. P., 15.04.2024, In: HELIYON. 10, 7, p. e29239

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Lower microhardness along with less heterogeneous mineralization in the femoral neck of individuals with type 2 diabetes mellitus indicates higher fracture risk

    Cirovic, A., Schmidt, F. N., Vujacic, M., Sihota, P., Petrovic, B., Zivkovic, V., Bascarevic, Z., Nikolic, S., Djonic, D., Djuric, M., Busse, B. & Milovanovic, P., 03.2024, In: JBMR PLUS. 8, 3, p. ziae005

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Lysosomal enzyme trafficking: from molecular mechanisms to human diseases

    Braulke, T., Carette, J. E. & Palm, W., 03.2024, In: TRENDS CELL BIOL. 34, 3, p. 198-210 13 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  10. Mechanical induction of osteoanabolic Wnt1 promotes osteoblast differentiation via Plat

    Ahmad, M., Haffner-Luntzer, M., Schoppa, A., Najafova, Z., Lukic, T., Yorgan, T. A., Amling, M., Schinke, T. & Ignatius, A., 29.02.2024, In: FASEB J. 38, 4, e23489.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development

    Brylka, L. J., Alimy, A-R., Tschaffon-Müller, M. E. A., Jiang, S., Ballhause, T. M., Baranowsky, A., von Kroge, S., Delsmann, J., Pawlus, E., Eghbalian, K., Püschel, K., Schoppa, A., Haffner-Luntzer, M., Beech, D. J., Beil, F. T., Amling, M., Keller, J., Ignatius, A., Yorgan, T. A., Rolvien, T. & Schinke, T., 23.02.2024, In: BONE RES. 12, 1, p. 12

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Age-related changes in the midpalatal suture: Comparison between CBCT staging and bone micromorphology

    Georgi, G. M., Knauth, S., Hirsch, E., Schulz-Kornas, E., Kahl-Nieke, B., Püschel, K., Amling, M., Koehne, T., Korbmacher-Steiner, H. & Petersen, J., 02.2024, In: BONE. 179, 116984.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling

    Hendrickx, G., Boudin, E., Mateiu, L., Yorgan, T. A., Steenackers, E., Kneissel, M., Kramer, I., Mortier, G., Schinke, T. & Van Hul, W., 02.2024, In: CALCIFIED TISSUE INT. 114, 2, p. 171-181 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Bisphosphonate Use and Periprosthetic Fractures

    Alimy, A-R., Beil, F. T., Amling, M. & Rolvien, T., 01.2024, In: J ARTHROPLASTY. 39, 1, p. e1-e2

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  15. 2023
  16. Cholesteatoma Severely Impacts the Integrity and Bone Material Quality of the Incus

    Delsmann, M. M., Bonik, P., Ocokoljic, A., Häussler, S. M., Püschel, K., Praetorius, M., Amling, M., Peichl, J. & Rolvien, T., 12.2023, In: CALCIFIED TISSUE INT. 113, 6, p. 609-617 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Comparison of Motion Grading in 1,000 Patients by First- and Second-Generation HR-pQCT: A Propensity Score Matched Cohort Study

    Bartosik, M., Simon, A., Strahl, A., Oheim, R., Amling, M. & Schmidt, F. N., 12.2023, In: CALCIFIED TISSUE INT. 113, 6, p. 597-608 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Epidemiology of Tumor-Induced Osteomalacia in Germany Based on Real World Data

    May, M., Oheim, R., Bovy, L., Doess, A., Maessen, D., Neukirch, B., Norris, R., Williams, A. & Abrahamsen, B., 12.2023, In: CALCIFIED TISSUE INT. 113, 6, p. 630-639 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage

    Danyukova, T., Alimy, A-R., Velho, R. V., Yorgan, T. A., Di Lorenzo, G., von Kroge, S., Tidow, H., Wiegert, J. S., Hermans-Borgmeyer, I., Schinke, T., Rolvien, T. & Pohl, S., 12.2023, In: BONE. 177, 116927.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Micropetrosis: Osteocyte Lacunar Mineralization in Aging and Disease

    Milovanovic, P. & Busse, B., 12.2023, In: CURR OSTEOPOROS REP. 21, 6, p. 750-757 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  21. Utility and Limitations of TALLYHO/JngJ as a Model for Type 2 Diabetes-Induced Bone Disease

    Emini, L., Salbach-Hirsch, J., Krug, J., Jähn-Rickert, K., Busse, B., Rauner, M. & Hofbauer, L. C., 12.2023, In: JBMR PLUS. 7, 12, e10843.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. When Cortical Bone Matrix Properties Are Indiscernible between Elderly Men with and without Type 2 Diabetes, Fracture Resistance Follows Suit

    Wölfel, E. M., Bartsch, B., Koldehoff, J., Fiedler, I. A. K., Dragoun-Kolibova, S., Schmidt, F. N., Krug, J., Lin, M-C., Püschel, K., Ondruschka, B., Zimmermann, E. A., Jelitto, H., Schneider, G., Gludovatz, B. & Busse, B., 12.2023, In: JBMR PLUS. 7, 12, p. e10839

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Empfehlungen zur Versorgung von Patient:innen mit FOP

    Seefried, L., Banholzer, D., Fischer, R., Grafe, I., Hüning, I., Morhart, R., Oheim, R., Semler, O., Siggelkow, H., Stockklausner, C. & Hoyer-Kuhn, H., 11.2023, In: ORTHOPADIE. 52, 11, p. 924-930 7 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  24. Fractal analysis of the mandible cortical bone: correlation among fractal dimension values obtained by two processing methods from periapical radiograph and micro-computed tomography with cone-beam computed tomography

    de Oliveira Loures, A., de Abreu, M., Devito, K. L., Grisolia-Seifert, E. F., Jähn-Rickert, K. & Rabelo, G. D., 11.2023, In: RADIAT ENVIRON BIOPH. 62, 4, p. 511-518 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. The selective norepinephrine reuptake inhibitor reboxetine promotes late-stage fracture healing in mice

    Donat, A., Jiang, S., Xie, W., Knapstein, P. R., Albertsen, L-C., Kokot, J. L., Sevecke, J., Augustin, R., Jahn, D., Yorgan, T. A., Frosch, K-H., Tsitsilonis, S., Baranowsky, A. & Keller, J., 20.10.2023, In: ISCIENCE. 26, 10, 107761.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease

    Mellor, L. F., Gago-Lopez, N., Bakiri, L., Schmidt, F. N., Busse, B., Rauber, S., Jimenez, M., Megías, D., Oterino-Soto, S., Sanchez-Prieto, R., Grivennikov, S., Pu, X., Oxford, J., Ramming, A., Schett, G. & Wagner, E. F., 18.10.2023, In: ANN RHEUM DIS. 81, 10, p. 1400-1408 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Do Clinical Parameters Reflect Local Bone Metabolism in Heterotopic Ossification After Septic or Aseptic THA?

    von Kroge, S., Büyükyilmaz, Z., Alimy, A-R., Hubert, J., Citak, M., Amling, M., Beil, F. T., Ohlmeier, M. & Rolvien, T., 01.10.2023, In: CLIN ORTHOP RELAT R. 481, 10, p. 2029-2041 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Zinc and vitamin D deficiency and supplementation in hypophosphatasia patients: A retrospective study

    Wiedemann, P., Schmidt, F. N., Amling, M., Yorgan, T. A. & Barvencik, F., 10.2023, In: BONE. 175, 116849.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. AXIN1 bi-allelic variants disrupting the C-terminal DIX domain cause craniometadiaphyseal osteosclerosis with hip dysplasia

    Terhal, P., Venhuizen, A. J., Lessel, D., Tan, W-H., Alswaid, A., Grün, R., Alzaidan, H. I., von Kroge, S., Ragab, N., Hempel, M., Kubisch, C., Novais, E., Cristobal, A., Tripolszki, K., Bauer, P., Fischer-Zirnsak, B., Nievelstein, R. A. J., van Dijk, A., Nikkels, P., Oheim, R., Hahn, H., Bertoli-Avella, A., Maurice, M. M. & Kornak, U., 07.09.2023, In: AM J HUM GENET. 110, 9, p. 1470-1481 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. TMCO3, a Putative K+ :Proton Antiporter at the Golgi Apparatus, Is Important for Longitudinal Growth in Mice and Humans

    Holling, T., Brylka, L. J., Scholz, T., Bierhals, T., Herget, T., Meinecke, P., Schinke, T., Oheim, R. & Kutsche, K., 09.2023, In: J BONE MINER RES. 38, 9, p. 1334-1349 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Why animal experiments are still indispensable in bone research: A statement by the European Calcified Tissue Society

    Stein, M., Elefteriou, F., Busse, B., Fiedler, I. A. K., Kwon, R. Y., Farell, E., Ahmad, M., Ignatius, A., Grover, L., Geris, L. & Tuckermann, J., 08.2023, In: J BONE MINER RES. 38, 8, p. 1045-1061 17 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  32. Increased beta2-adrenergic signaling is a targetable stimulus essential for bone healing by promoting callus neovascularization

    Jahn, D., Knapstein, P. R., Otto, E., Köhli, P., Sevecke, J., Graef, F., Graffmann, C., Fuchs, M., Jiang, S., Rickert, M., Erdmann, C., Appelt, J., Revend, L., Küttner, Q., Witte, J., Rahmani, A., Duda, G., Xie, W., Donat, A., Schinke, T., Ivanov, A., Tchouto, M. N., Beule, D., Frosch, K-H., Baranowsky, A., Tsitsilonis, S. & Keller, J., 16.07.2023, In: bioRxiv.

    Research output: SCORING: Contribution to journalPreprintResearch

  33. Fracture healing in a mouse model of Hajdu–Cheney-Syndrome with high turnover osteopenia results in decreased biomechanical stability

    Ballhause, T. M., Jiang, S., Xie, W., Sevecke, J., Dowling, C., Dust, T., Brandt, S., Mertens, P. R., Yorgan, T. A., Schinke, T., Frosch, K-H., Baranowsky, A. & Keller, J., 14.07.2023, In: SCI REP-UK. 13, 1, p. 11418 11418.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. CNS Manifestations in Mucolipidosis Type II-A Retrospective Analysis of Longitudinal Data on Neurocognitive Development and Neuroimaging in Eleven Patients

    Ammer, L. S., Täuber, K., Perez, A., Dohrmann, T., Denecke, J., Santer, R., Blümlein, U., Ozga, A-K., Pohl, S. & Muschol, N. M., 18.06.2023, In: J CLIN MED. 12, 12, 4114.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Mechanical-induced bone remodeling does not depend on Piezo1 in dentoalveolar hard tissue

    Nottmeier, C., Lavicky, J., Gonzalez Lopez, M., Knauth, S., Kahl-Nieke, B., Amling, M., Schinke, T., Helms, J., Krivanek, J., Koehne, T. & Petersen, J., 12.06.2023, In: SCI REP-UK. 13, 1, 9563.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Efficacy of zoledronic acid for the elimination of disseminated tumor cells in a clinically relevant, spontaneously metastatic prostate cancer xenograft model

    Böckelmann, L. C., Freytag, V., Ahlers, A-K., Maar, H., Gosau, T., Baranowsky, A., Schmitz, R., Pantel, K., Schumacher, U., Haider, M-T. & Lange, T., 06.2023, In: BONE. 171, p. 116741

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Effects of more natural housing conditions on the muscular and skeletal characteristics of female C57BL/6J mice

    Mieske, P., Scheinpflug, J., Yorgan, T. A., Brylka, L., Palme, R., Hobbiesiefken, U., Preikschat, J., Lewejohann, L. & Diederich, K., 16.05.2023, In: LAB ANIM RES. 39, 1, p. 9

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Bone mineral density and microarchitecture change during skeletal growth in harbor seals (Phoca vitulina) from the German coast

    Delsmann, J., Schmidt, B., Oheim, R., Amling, M., Rolvien, T. & Siebert, U., 03.05.2023, In: SCI REP-UK. 13, 1, 7196.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Osteocyte apoptosis and cellular micropetrosis signify skeletal aging in type 1 diabetes

    Dragoun Kolibová, S., Wölfel, E. M., Hemmatian, H., Milovanovic, P., Mushumba, H., Wulff, B., Neidhardt, M., Püschel, K., Failla, A. V., Vlug, A., Schlaefer, A., Ondruschka, B., Amling, M., Hofbauer, L. C., Rauner, M., Busse, B. & Jähn-Rickert, K., 05.2023, In: ACTA BIOMATER. 162, p. 254-265 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Radiolucent zones of biodegradable magnesium-based screws in children and adolescents-a radiographic analysis

    Delsmann, M. M., Stürznickel, J., Kertai, M., Stücker, R., Rolvien, T. & Rupprecht, M., 05.2023, In: ARCH ORTHOP TRAUM SU. 143, 5, p. 2297-2305 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Wnt1 Boosts Fracture Healing by Enhancing Bone Formation in the Fracture Callus

    Haffner-Luntzer, M., Ragipoglu, D., Ahmad, M., Schoppa, A., Steppe, L., Fischer, V., Luther, J., Yorgan, T., Bockamp, E., Amling, M., Schinke, T. & Ignatius, A., 05.2023, In: J BONE MINER RES. 38, 5, p. 749-764 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune glomerulonephritis

    Reichelt, J., Sachs, W., Frömbling, S., Fehlert, J., Studencka-Turski, M., Betz, A., Loreth, D., Blume, L., Witt, S., Pohl, S., Brand, J., Czesla, M., Knop, J., Florea, B. I., Zielinski, S., Sachs, M., Hoxha, E., Hermans-Borgmeyer, I., Zahner, G., Wiech, T., Krüger, E. & Meyer-Schwesinger, C., 13.04.2023, In: NAT COMMUN. 14, 1, p. 2114

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Effects of Infantile Hypophosphatasia on Human Dental Tissue

    Wölfel, E. M., von Kroge, S., Matthies, L., Köhne, T., Petz, K., Beikler, T., Schmid-Herrmann, C., Kahl-Nieke, B., Tsiakas, K., Santer, R., Muschol, N. M., Herrmann, J., Busse, B., Amling, M., Rolvien, T., Jandl, N. M. & Barvencik, F., 03.2023, In: CALCIFIED TISSUE INT. 112, 3, p. 308-319 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Ex Vivo Model of Neuroblastoma Plasticity

    Schäfer, P., Muhs, S., Turnbull, L., Garwal, P., Maar, H., Yorgan, T. A., Tolosa, E., Lange, T. & Windhorst, S., 17.02.2023, In: CANCERS. 15, 4, 1274.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Age-, sex- and subregion-specific properties of distal fibular microarchitecture and strength: an ex vivo HR-pQCT study

    Schlickewei, C., Schweizer, C., Püschel, K., Ondruschka, B., Kleinertz, H., Barg, A., Rolvien, T. & Stürznickel, J., 02.2023, In: J ORTHOP RES. 41, 2, p. 355-363 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Impact of polyethylene glenoid cementation technique on cement mantle integrity and stability after cyclic loading: a computed tomography and biomechanical study

    Kasten, P., Jandl, N. M., Zeifang, F., Dallmann, F., Jakobs, S., Stalder, K. & Niemeier, A., 02.2023, In: J SHOULDER ELB SURG. 32, 2, p. 383-391 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Denosumab and muscle performance

    Rolvien, T., Rupp, T., Strahl, A. & Amling, M., 01.2023, In: OSTEOPOROSIS INT. 34, 1, p. 211-212 2 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  48. On the fracture behavior of cortical bone microstructure: The effects of morphology and material characteristics of bone structural components

    Allahyari, P., Silani, M., Yaghoubi, V., Milovanovic, P., Schmidt, F. N., Busse, B. & Qwamizadeh, M., 01.2023, In: J MECH BEHAV BIOMED. 137, 105530.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Reduced Bone Mass and Increased Osteocyte Tartrate-Resistant Acid Phosphatase (TRAP) Activity, But Not Low Mineralized Matrix Around Osteocyte Lacunae, Are Restored After Recovery From Exogenous Hyperthyroidism in Male Mice

    Wölfel, E. M., Lademann, F., Hemmatian, H., Blouin, S., Messmer, P., Hofbauer, L. C., Busse, B., Rauner, M., Jähn-Rickert, K. & Tsourdi, E., 01.2023, In: J BONE MINER RES. 38, 1, p. 131-143 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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