Institute of Neuropathology
Publications
- 2013
Supra- and infratentorial pediatric ependymomas differ significantly in NeuN, p75 and GFAP expression
Hagel, C., Treszl, A., Fehlert, J., Harder, J., von Haxthausen, F., Kern, M., von Bueren, A. O. & Kordes, U., 01.04.2013, In: J NEURO-ONCOL. 112, 2, p. 191-7 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CLP1 links tRNA metabolism to progressive motor-neuron loss
Hanada, T., Weitzer, S., Mair, B., Bernreuther, C., Wainger, B. J., Ichida, J., Hanada, R., Orthofer, M., Cronin, S. J., Komnenovic, V., Minis, A., Sato, F., Mimata, H., Yoshimura, A., Tamir, I., Rainer, J., Kofler, R., Yaron, A., Eggan, K. C., Woolf, C. J., Glatzel, M., Herbst, R., Martinez, J. & Penninger, J. M., 28.03.2013, In: NATURE. 495, 7442, p. 474-80 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice
Santuccione, A. C., Merlini, M., Shetty, A., Tackenberg, C., Bali, J., Ferretti, M. T., McAfoose, J., Kulic, L., Bernreuther, C., Welt, T., Grimm, J., Glatzel, M., Rajendran, L., Hock, C. & Nitsch, R. M., 01.03.2013, In: MOL PSYCHIATR. 18, 3, p. 358-68 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel interaction between aging and ER overload in a protein conformational dementia
Schipanski, A., Lange, S., Segref, A., Gutschmidt, A., Lomas, D. A., Miranda, E., Schweizer, M., Hoppe, T. & Glatzel, M., 01.03.2013, In: GENETICS. 193, 3, p. 865-76 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Truncating mutations in FUS/TLS give rise to a more aggressive ALS-phenotype than missense mutations: a clinico-genetic study in Germany
Waibel, S., Neumann, M., Rosenbohm, A., Birve, A., Volk, A. E., Weishaupt, J. H., Meyer, T., Müller, U., Andersen, P. M. & Ludolph, A. C., 03.2013, In: EUR J NEUROL. 20, 3, p. 540-6 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Constitutive activation of β-catenin in neural progenitors results in disrupted proliferation and migration of neurons within the central nervous system
Pöschl, J., Grammel, D., Dorostkar, M. M., Kretzschmar, H. A. & Schüller, U., 15.02.2013, In: DEV BIOL. 374, 2, p. 319-32 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hemophagocytic lymphohistiocytosis in syntaxin-11-deficient mice: T-cell exhaustion limits fatal disease
Kögl, T., Müller, J., Jessen, B., Schmitt-Graeff, A., Janka-Schaub, G., Ehl, S., zur Stadt, U. & Aichele, P., 24.01.2013, In: BLOOD. 121, 4, p. 604-13 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Amyloid-precursor-protein-lowering small molecules for disease modifying therapy of Alzheimer's disease
Rosenkranz, S. C., Geissen, M., Härter, K., Szalay, B., Ferrer, I., Vogel, J., Smith, S. & Glatzel, M., 01.01.2013, In: PLOS ONE. 8, 12, p. e82255Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Apoptotic photoreceptor loss and altered expression of lysosomal proteins in the nclf mouse model of neuronal ceroid lipofuscinosis
Bartsch, U., Galliciotti, G., Jofre, G. F., Jankowiak, W., Hagel, C. & Braulke, T., 01.01.2013, In: INVEST OPHTH VIS SCI. 54, 10, p. 6952-9 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cellular Composition of Cerebrospinal Fluid in HIV-1 Infected and Uninfected Subjects
Ho, E. L., Ronquillo, R., Altmeppen, H., Spudich, S. S., Price, R. W. & Sinclair, E., 01.01.2013, In: PLOS ONE. 8, 6, p. e66188Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparative effectiveness of 18F-FDG PET/CT versus whole-body MRI for detection of malignant peripheral nerve sheath tumors in neurofibromatosis type 1
Derlin, T., Tornquist, K., Münster, S., Apostolova, I., Hagel, C., Friedrich, R. E., Wedegärtner, U. & Mautner, V-F., 01.01.2013, In: CLIN NUCL MED. 38, 1, p. e19-25Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation
Gelderblom, M., Neumann, M., Ludewig, P., Bernreuther, C., Krasemann, S., Arunachalam, P., Gerloff, C., Glatzel, M. & Magnus, T., 01.01.2013, In: PLOS ONE. 8, 5, p. e63118Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke
Fann, D. Y-W., Lee, S. Y., Manzanero, S., Tang, S. C., Gelderblom, M., Chunduri, P., Bernreuther, C., Glatzel, M., Cheng, Y. L., Thundyil, J., Widiapradja, A., Lok, K. Z., Foo, S. L., Wang, Y. C., Li, Y. I., Drummond, G. R., Basta, M., Magnus, T., Jo, D. G., Mattson, M. P., Sobey, C. G. & Arumugam, T. V., 01.01.2013, In: CELL DEATH DIS. 4, p. e790Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Myositis facilitates preclinical accumulation of pathological prion protein in muscle
Neumann, M., Krasemann, S., Schröck, K., Steinbach, K. & Glatzel, M., 01.01.2013, In: ACTA NEUROPATHOL COM. 1, 1, p. 78Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Age-related appearance of dendritic inclusions in catecholaminergic brainstem neurons.
Braak, H., Thal, D. R., Matschke, J., Ghebremedhin, E. & Kelly, D. T., 2013, In: NEUROBIOL AGING. 34, 1, p. 286-297 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
B-scan ultrasonographic monitoring of orthotopic xenografted plexiform neurofibroma in mice
Gleiss, J., Demestre, M., Spyra, M., Eschenhagen, T., Hagel, C., Mautner, V-F., Kluwe, L. & Friedrich, R. E., 2013, In: IN VIVO. 27, 6, p. 723-7 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cytogenetics of extramedullary manifestations in multiple myeloma
Billecke, L., Murga Penas, E. M., May, A. M., Engelhardt, M., Nagler, A., Leiba, M., Schiby, G., Kröger, N., Zustin, J., Marx, A., Matschke, J., Tiemann, M., Goekkurt, E., Heidtmann, H-H., Vettorazzi, E., Dierlamm, J., Bokemeyer, C. & Schilling, G., 2013, In: BRIT J HAEMATOL. 161, 1, p. 87-94 8 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease.
Pera, M., Alcolea, D., Sánchez-Valle, R., Guardia-Laguarta, C., Colom-Cadena, M., Badiola, N., Suárez-Calvet, M., Lladó, A., Barrera-Ocampo, A. A., Sepulveda-Falla, D., Blesa, R., Molinuevo, J. L., Clarimón, J., Ferrer, I., Gelpi, E. & Lleó, A., 2013, In: ACTA NEUROPATHOL. 125, 2, p. 201-213 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disturbed energy metabolism and muscular dystrophy caused by pure creatine deficiency are reversible by creatine intake.
Nabuurs, C. I., Choe, C-U., Veltien, A., Kan, H. E., van Loon, L. J. C., Rodenburg, R. J. T., Matschke, J., Wieringa, B., Kemp, G. J., Isbrandt, D. & Heerschap, A., 2013, In: J PHYSIOL-LONDON. 591, Pt 2, p. 571-592 Pt 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
EHEC-O104:H4-Ausbruch im Sommer 2011: Charakterisierung der Hamburger Todesfälle
Fründt, T. W., Höpker, W-W., Hagel, C., Sperhake, J., Isenberg, AH., Lüth, S., Lohse, A. W., Sauter, G., Glatzel, M. & Püschel, K., 2013, In: RECHTSMEDIZIN. 23, p. 374–382Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Forensische Pädopathologie: Plötzlicher Tod eines fünf Monate alt gewordenen männlichen Säuglings.
Matschke, J., Bernreuther, C., Schulz, F., Andresen-Streichert, H. & Püschel, K., 2013, In: päd Praktische Pädiatrie. 19, p. 139-141 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Heterozygosity for the mutated X-chromosome-linked L1 cell adhesion molecule gene leads to increased numbers of neurons and enhanced metabolism in the forebrain of female carrier mice.
Schmid, J. S., Bernreuther, C., Nikonenko, A., Ling, Z., Mies, G., Hossmann, K-A., Jakovcevski, I. & Schachner, M., 2013, In: BRAIN STRUCT FUNCT. 218, 6, p. 1375-1390 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of protein content on proton diffusibility in intracranial cysts.
Goebell, E., Fiehler, J., Martens, T., Hagel, C., Forkert, N. D., Russjan, A., Rosenkranz, M., Buhk, J-H., Groth, M. & Sedlacik, J., 2013, In: ROFO-FORTSCHR RONTG. 185, 1, p. 60-65 6 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Klinisch-forensische Medizin: Kindesmisshandlung
Sperhake, J. & Matschke, J., 2013, 1 ed. Wien: Springer Wien. 18 p.Research output: Book/anthology › Collected edition/anthology › Transfer
Molecular Mechanisms of Prion Diseases
Altmeppen, H. C., Puig Martorell, B., Krasemann, S., Falker, C., Dohler, F. & Glatzel, M., 2013, Prions: Current Progress in Advanced Research. Sakudo, A. & Onodera, T. (eds.). 1 ed. Caister Academic Press, p. 41-54 14 p. 5Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Neuropathologie der Enzephalopathien
Hagel, C., 2013, Berlin: Springer.Research output: Book/anthology › Collected edition/anthology › Education
Protease-sensitive prion species in neoplastic spleens of prion-infected mice with uncoupling of PrP(Sc) and prion infectivity.
Krasemann, S., Neumann, M., Szalay, B., Stocking, C. & Glatzel, M., 2013, In: J GEN VIROL. 94, Pt 2, p. 453-463 11 p., Pt 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Refinement of IKZF1 recombination hotspots in pediatric BCP-ALL patients.
Meyer, C., Zur Stadt, U., Escherich, G., Hofmann, J., Binato, R., Barbosa, T. D. C., Emerenciano, M., Pombo-de-Oliveira, M. S., Horstmann, M. & Marschalek, R., 2013, In: AM J BLOOD RES. 3, 2, p. 165-173 9 p., 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Skeletal spread of an anaplastic astrocytoma (WHO grade III) and preservation of histopathological properties within metastases.
Martens, T., Matschke, J., Müller, C., Riethdorf, S., Balabanov, S., Westphal, M. & Heese, O., 2013, In: CLIN NEUROL NEUROSUR. 115, 3, p. 323-328 6 p., 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Syntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulation.
D'Orlando, O., Zhao, F., Kasper, B., Orinska, Z., Müller, J., Hermans-Borgmeyer, I., Griffiths, G. M., Zur Stadt, U. & Bulfone-Paus, S., 2013, In: EUR J IMMUNOL. 43, 1, p. 194-208 15 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
Potentially clinically relevant prostate cancer is found more frequently after complete than after partial histopathological processing of radical cystoprostatectomy specimens
Fritsche, H. M., Aziz, A., Eder, F., Otto, W., Denzinger, S., Wieland, W. F., May, M., Hofstädter, F., Hartmann, A. & Burger, M., 12.2012, In: VIRCHOWS ARCH. 461, 6, p. 655-61 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ALDH1A1 is a marker of astrocytic differentiation during brain development and correlates with better survival in glioblastoma patients
Adam, S. A., Schnell, O., Pöschl, J., Eigenbrod, S., Kretzschmar, H. A., Tonn, J-C. & Schüller, U., 11.2012, In: BRAIN PATHOL. 22, 6, p. 788-97 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours.
von Bueren, A., Bacolod, M. D., Hagel, C., Heinimann, K., Fedier, A., Kordes, U., Pietsch, T., Koster, J., Grotzer, M. A., Friedman, H. S., Marra, G., Kool, M. & Rutkowski, S., 09.10.2012, In: BRIT J CANCER. 107, 8, p. 1399-1408 10 p., 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Surgery for atypical plexiform neurofibromas of the trunk in NF1 with high standardised uptake value (SUV) in positron-emission tomography (PET) expressing podoplanin: a long-term follow-up.
Friedrich, R., Gawad, K., Derlin, T., Zustin, J. & Hagel, C., 01.10.2012, In: ANTICANCER RES. 32, 10, p. 4547-4551 5 p., 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ataxia and HIV: clinicopathologic correlations in a case of HIV-associated cerebellar leukoencephalopathy.
Ganos, C., Bernreuther, C., Matschke, J., Gerloff, C., Münchau, A. & Leypoldt, F., 01.09.2012, In: CEREBELLUM. 11, 3, p. 816-819 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Letter to the editor
Schnell, O., Pöschl, J., Tonn, J. & Schüller, U., 09.2012, In: BRAIN PATHOL. 22, 5, p. 724Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distinct mutations in STXBP2 are associated with variable clinical presentations in patients with familial hemophagocytic lymphohistiocytosis type 5 (FHL5)
Pagel, J., Beutel, K., Lehmberg, K., Koch, F., Maul-Pavicic, A., Rohlfs, A-K., Al-Jefri, A., Beier, R., Lilian, B. O., Ehlert, K., Gross-Wieltsch, U., Jorch, N., Kremens, B., Pekrun, A., Sparber-Sauer, M., Mejstrikova, E., Wawer, A., Ehl, S., Zur Stadt, U. & Janka-Schaub, G., 21.06.2012, In: BLOOD. 119, 25, p. 6016-6024 9 p., 25.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hereditäre kardiale Amyloidosen mit Mutationen des Transthyretin. Ursache des plötzlichen Todes
Edler, C., Saeger, W., Orth, U., Braun, C., Wulff, B. & Sperhake, J., 01.06.2012, In: HERZ. 37, 4, p. 456-60 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bitte nicht schütteln!
Matschke, J., 12.02.2012, In: Süddeutsche Zeitung.Research output: SCORING: Contribution to journal › Newspaper articles › Transfer
Adhesion molecule L1 is down-regulated in malignant peripheral nerve sheath tumors versus benign neurofibromatosis type 1-associated tumors
Blessmann, M., Gröbe, A., Quaas, A., Kaifi, J. T., Mistakidis, G., Bernreuther, C., Sauter, G., Gros, S., Rawnaq, T., Friedrich, R., Mautner, V. F., Smeets, R., Heiland, M., Schachner, M. & Izbicki, J. R., 01.02.2012, In: OR SURG OR MED OR PA. 113, 2, p. 239-44 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Activation of the Nipah virus fusion protein in MDCK cells is mediated by cathepsin B within the endosome-recycling compartment.
Diederich, S., Sauerhering, L., Weis, M., Altmeppen, H. C., Schaschke, N., Reinheckel, T., Erbar, S. & Maisner, A., 2012, In: J VIROL. 86, 7, p. 3736-3745 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes.
Bryceson, Y. T., Pende, D., Maul-Pavicic, A., Gilmour, K. C., Ufheil, H., Vraetz, T., Chiang, S. C., Marcenaro, S., Meazza, R., Bondzio, I., Walshe, D., Janka-Schaub, G., Lehmberg, K., Beutel, K., Zur Stadt, U., Binder, N., Arico, M., Moretta, L., Henter, J-I. & Ehl, S., 2012, In: BLOOD. 119, 12, p. 2754-2763 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical presentation, immunohistochemistry and electron microscopy indicate neurofibromatosis type 2-associated gliomas to be spinal ependymomas.
Hagel, C., Stemmer-Rachamimov, A. O., Bornemann, A., Schuhmann, M., Nagel, C., Huson, S., Evans, D. G., Plotkin, S., Matthies, C., Kluwe, L. & Mautner, V. F., 2012, In: NEUROPATHOLOGY. 32, 6, p. 611-616 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis.
Thelen, M., Damme, M., Daμμe, M., Schweizer, M., Hagel, C., Wong, A. M. S., Cooper, J. D., Braulke, T. & Galliciotti, G., 2012, In: PLOS ONE. 7, 4, p. 35493 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DNA copy number alterations in central primitive neuroectodermal tumors and tumors of the pineal region: an international individual patient data meta-analysis.
von Bueren, A., André, O., Hagel, C., Hagel, C., Cai, H., Remke, M., Hasselblatt, M., Feuerstein, B. G., Pernet, S., Delattre, O., Rutkowski, S., Rutkowski, S., Pfister, S. M. & Baudis, M., 2012, In: J NEURO-ONCOL. 109, 2, p. 415-423 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.
Preukschas, M., Hagel, C., Schulte, A., Riecken, K., Lamszus, K., Sievert, H., Pällmann, N., Bokemeyer, C., Hauber, J., Balabanov, M. & Balabanov, S., 2012, In: PLOS ONE. 7, 8, p. 43468 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of podoplanin in primary and metastatic poorly differentiated and undifferentiated carcinomas of the head and neck.
Friedrich, R., Bartel-Friedrich, S. & Hagel, C., 2012, In: ANTICANCER RES. 32, 5, p. 2019-2022 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fatal EBV infection and variable clinical manifestations in an XLP-1 pedigree - rapid diagnosis of primary immunodeficiencies may save lives.
Sperl, D., Benesch, M., Urban, C., Lackner, H., Sovinz, P., Speicher, M. R., Uhrig, S., Schwarzbraun, T., Schwinger, W., Zur Stadt, U., Beutel, K., Janka-Schaub, G., Scarpatetti, M. & Seidel, M. G., 2012, In: KLIN PADIATR. 224, 6, p. 386-389 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Forensische Pädopathologie - Letale intrakranielle Blutungen auf dem Boden einer akuten Immunthrombozytopenie
Neumann, L., Püschel, K., Matschke, J., Fiehler, J. & Anders, S., 2012, In: päd Praktische Pädiatrie. 18, 1, p. 44-50 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Hereditary cardiac amyloidosis with transthyretin mutations. A cause of sudden death ].
Edler, C., Saeger, W., Orth, U., Braun, C., Wulff, B. & Sperhake, J., 2012, In: HERZ. 37, 4, p. 456-460 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review