Department of Biochemistry and Molecular Cell Biology
Publications
- 2004
Differential RNA interference: replacement of endogenous with recombinant low density lipoprotein receptor-related protein (LRP).
Laatsch, A., Ragozin, S., Grewal, T., Beisiegel, U. & Joerg, H., 2004, In: EUR J CELL BIOL. 83, 3, p. 113-120 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation.
Heeren, J., Grewal, T., Laatsch, A., Becker, N., Rinninger, F., Rye, K-A. & Beisiegel, U., 2004, In: J BIOL CHEM. 279, 53, p. 55483-55492 53.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interaction of artificial metallic objects with biosusceptometric measurements.
Engelhardt, R., Fung, E. B., Kelly, P., Biehl, T. R., Pakbaz, Z., Nielsen, P., Harmatz, P. & Fischer, R., 2004, In: Neurol Clin Neurophysiol. 2004, p. 32Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low dose-ethanol modulates toxic effect of iron-overloading in the liver.
Beutelspacher, S. C., Serbecic, N., Tan, P. H., Mehrabi, M., Nielsen, P. & Yamane, Y., 2004, In: J NUTR SCI VITAMINOL. 50, 2, p. 78-86 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2003
Effective treatment of hereditary haemochromatosis with desferrioxamine in selected cases.
Nielsen, P., Fischer, R., Buggisch, P. & Janka-Schaub, G., 2003, In: BRIT J HAEMATOL. 123, 5, p. 952-953 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monitoring long-term efficacy of iron chelation therapy by deferiprone and desferrioxamine in patients with beta-thalassaemia major: application of SQUID biomagnetic liver susceptometry.
Fischer, R., Longo, F., Nielsen, P., Engelhardt, R., Hider, R. C. & Piga, A., 2003, In: BRIT J HAEMATOL. 121, 6, p. 938-948 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Recycling of apoprotein E is associated with cholesterol efflux and high density lipoprotein internalization.
Heeren, J., Grewal, T., Laatsch, A., Rottke, D., Rinninger, F., Enrich, C. & Beisiegel, U., 2003, In: J BIOL CHEM. 278, 16, p. 14370-14378 16.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2002
Human mesenchymal stem cells are not of donor origin in patients with severe aplastic anemia who underwent sex-mismatched allogeneic bone marrow transplant
Stute, N., Fehse, B., Schröder, J., Arps, S., Adamietz, P., Held, K. R. & Zander, A. R., 12.2002, In: J HEMATOTH STEM CELL. 11, 6, p. 977-984 8 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
Characterization of the VPS10 domain of SorLA/LR11 as binding site for the neuropeptide HA.
Lintzel, J., Franke, I., Riedel, I. B., Schaller, H. C. & Hampe, W., 2002, In: BIOL CHEM. 383, 11, p. 1727-1733 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors.
Wittenberger, T., Hellebrand, S., Munck, A., Kreienkamp, H-J., Schaller, H. C. & Hampe, W., 2002, In: BMC GENOMICS. 3, 1, p. 17 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Non-invasive liver iron quantification by SQUID-biosusceptometry and serum ferritin iron as new diagnostic parameters in hereditary hemochromatosis.
Nielsen, P., Engelhardt, R., Düllmann, J. & Fischer, R., 2002, In: BLOOD CELL MOL DIS. 29, 3, p. 451-458 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[SQUID-biosusceptometry in iron overloaded patients with hematologic diseases]
Nielsen, P., Kordes, U., Fischer, R., Engelhardt, R. & Janka-Schaub, G., 2002, In: KLIN PADIATR. 214, 4, p. 218-222 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2001
Identification of a cis-acting element and a novel trans-acting factor of the glutamine synthetase gene in liver cells.
Gaunitz, F., Weber, S., Scheja, L. & Gebhardt, R., 2001, In: BIOCHEM BIOPH RES CO. 284, 2, p. 377-383 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification of SorCS2, a novel member of the VPS10 domain containing receptor family, prominently expressed in the developing mouse brain.
Rezgaoui, M., Hermey, G., Riedel, I. B., Hampe, W., Schaller, H. C. & Hermans-Borgmeyer, I., 2001, In: MECH DEVELOP. 100, 2, p. 335-338 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The genes for the human VPS10 domain-containing receptors are large and contain many small exons.
Hampe, W., Rezgaoui, M., Hermans-Borgmeyer, I. & Schaller, H. C., 2001, In: HUM GENET. 108, 6, p. 529-536 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The neuropeptide head activator induces activation and translocation of the growth-factor-regulated Ca(2+)-permeable channel GRC.
Boels, K., Glassmeier, G., Herrmann, D., Riedel, I. B., Hampe, W., Kojima, I., Schwarz, J. R. & Schaller, H. C., 2001, In: J CELL SCI. 114, 20, p. 3599-3606 20.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2000
Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C.
Wegener, S., Hampe, W., Herrmann, D. & Schaller, H. C., 2000, In: EUR J CELL BIOL. 79, 11, p. 810-815 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterisation of receptor-specific TNFalpha functions in adipocyte cell lines lacking type 1 and 2 TNF receptors.
Sethi, J. K., Xu, H., Uysal, K. T., Wiesbrock, S. M., Scheja, L. & Hotamisligil, G. S., 2000, In: FEBS LETT. 469, 1, p. 77-82 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ectodomain shedding, translocation and synthesis of SorLA are stimulated by its ligand head activator.
Hampe, W., Riedel, I. B., Lintzel, J., Bader, C. O., Franke, I. & Schaller, H. C., 2000, In: J CELL SCI. 113, 24, p. 4475-4485 24.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Engineering of a proteolytically stable human beta 2-adrenergic receptor/maltose-binding protein fusion and production of the chimeric protein in Escherichia coli and baculovirus-infected insect cells.
Hampe, W., Voss, R. H., Haase, W., Boege, F., Michel, H. & Reiländer, H., 2000, In: J BIOTECHNOL. 77, 2-3, p. 219-234 2-3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impaired plasma antioxidative defense and increased nontransferrin-bound iron during high-dose chemotherapy and radiochemotherapy preceding bone marrow transplantation.
Dürken, M., Herrnring, C., Finckh, B., Nagel, S., Nielsen, P., Fischer, R., Berger, H. M., Moison, R. M., Pichlmeier, U., Kohlschütter, B., Zander, A. R. & Kohlschütter, A., 2000, In: FREE RADICAL BIO MED. 28, 6, p. 887-894 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Improved glucose and lipid metabolism in genetically obese mice lacking aP2.
Uysal, K. T., Scheja, L., Wiesbrock, S. M., Bonner-Weir, S. & Hotamisligil, G. S., 2000, In: ENDOCRINOLOGY. 141, 9, p. 3388-3396 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Serum ferritin iron in iron overload and liver damage: correlation to body iron stores and diagnostic relevance.
Nielsen, P., Günther, U., Dürken, M., Fischer, R. & Düllmann, J., 2000, In: J LAB CLIN MED. 135, 5, p. 413-418 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Using SQUID biomagnetic liver susceptometry in the treatment of thalassemia and other iron loading diseases.
Nielsen, P., Engelhardt, R., Duerken, M., Janka-Schaub, G. & Fischer, R., 2000, In: Transfus Sci. 23, 3, p. 257-258 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1999
A head-activator binding protein is present in hydra in a soluble and a membrane-anchored form.
Hampe, W., Urny, J., Franke, I., Hoffmeister-Ullerich, S. A., Herrmann, D., Petersen, C. M., Lohmann, J. & Schaller, H. C., 1999, In: DEVELOPMENT. 126, 18, p. 4077-4086 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Altered insulin secretion associated with reduced lipolytic efficiency in aP2-/- mice.
Scheja, L., Makowski, L., Uysal, K. T., Wiesbrock, S. M., Shimshek, D. R., Meyers, D. S., Morgan, M., Parker, R. A. & Hotamisligil, G. S., 1999, In: DIABETES. 48, 10, p. 1987-1994 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Assessment of iron stores in children with transfusion siderosis by biomagnetic liver susceptometry.
Fischer, R., Tiemann, C. D., Engelhardt, R., Nielsen, P., Dürken, M., Gabbe, E. E. & Janka-Schaub, G., 1999, In: AM J HEMATOL. 60, 4, p. 289-299 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Function of the neuropeptide head activator for early neural and neuroendocrine development.
Hampe, W., Hermans-Borgmeyer, I. & Schaller, H. C., 1999, In: Results Probl Cell Differ. 26, p. 323-337Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification and characterization of SorCS, a third member of a novel receptor family.
Hermey, G., Riedel, I. B., Hampe, W., Schaller, H. C. & Hermans-Borgmeyer, I., 1999, In: BIOCHEM BIOPH RES CO. 266, 2, p. 347-351 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-term survival in a patient with AIDS and hereditary haemochromatosis.
Nielsen, P., Degen, O., Brümmer, J. & Gabbe, E. E., 1999, In: EUR J HAEMATOL. 63, 3, p. 202-204 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1998
Effect of oral iron chelator L1 on iron absorption in man.
Dresow, B., Fischer, R., Nielsen, P., Gabbe, E. E. & Piga, A., 1998, In: ANN NY ACAD SCI. 850, p. 466-468Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Iron supplementation in athletes. Current recommendations.
Nielsen, P. & Nachtigall, D., 1998, In: SPORTS MED. 26, 4, p. 207-216 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Liver iron and fibrosis during long-term treatment with deferiprone in Swiss thalassaemic patients.
Töndury, P., Zimmermann, A., Nielsen, P. & Hirt, A., 1998, In: BRIT J HAEMATOL. 101, 3, p. 413-415 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Non-transferrin bound iron induced by myeloablative therapy.
Dürken, M., Kohlschütter, A. & Nielsen, P., 1998, In: BRIT J HAEMATOL. 101, 2, p. 393-394 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prevalence of the C282Y and H63D mutations in the HFE gene in patients with hereditary haemochromatosis and in control subjects from Northern Germany.
Nielsen, P., Carpinteiro, S., Fischer, R., Cabeda, J. M., Porto, G. & Gabbe, E. E., 1998, In: BRIT J HAEMATOL. 103, 3, p. 842-845 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Unique expression pattern of a novel mosaic receptor in the developing cerebral cortex.
Hermans-Borgmeyer, I., Hampe, W., Schinke, B., Methner, A., Nykjaer, A., Süsens, U., Fenger, U., Herbarth, B. & Schaller, H. C., 1998, In: MECH DEVELOP. 70, 1-2, p. 65-76 1-2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1997
Nontransferrin-bound iron in serum of patients receiving bone marrow transplants.
Dürken, M., Nielsen, P., Knobel, S., Finckh, B., Herrnring, C., Dresow, B., Kohlschütter, B., Stockschläder, M., Krüger, W. H., Kohlschütter, A. & Zander, A. R., 1997, In: FREE RADICAL BIO MED. 22, 7, p. 1159-1163 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Purification of a head-activator receptor from hydra.
Franke, I., Buck, F. & Hampe, W., 1997, In: EUR J BIOCHEM. 244, 3, p. 940-945 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Successful treatment of iron overload by phlebotomies in a patient with severe congenital dyserythropoietic anemia type II.
Hofmann, W. K., Kaltwasser, J. P., Hoelzer, D., Nielsen, P. & Gabbe, E. E., 1997, In: BLOOD. 89, 8, p. 3068-3069 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Treatment of cirrhotic rats with L-ornithine-L-aspartate enhances urea synthesis and lowers serum ammonia levels.
Gebhardt, R., Beckers, G., Gaunitz, F., Haupt, W., Jonitza, D., Klein, S. & Scheja, L., 1997, In: J PHARMACOL EXP THER. 283, 1, p. 1-6 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1996
Pregnancy after intracytoplasmic sperm injection of spermatozoa extracted from frozen-thawed testicular biopsy
Fischer, R., Baukloh, V., Naether, O. G., Schulze, W., Salzbrunn, A. & Benson, D. M., 10.1996, In: HUM REPROD. 11, 10, p. 2197-9 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Iron deficiency in distance runners. A reinvestigation using Fe-labelling and non-invasive liver iron quantification.
Nachtigall, D., Nielsen, P., Fischer, R., Engelhardt, R. & Gabbe, E. E., 1996, In: INT J SPORTS MED. 17, 7, p. 473-479 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Photoaffinity labeling of the head-activator receptor from hydra.
Hampe, W., Frank, R. W., Schulze, C., Dehning, I. & Schaller, H. C., 1996, In: EUR J BIOCHEM. 235, 3, p. 814-820 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1995
Ethane exhalation and vitamin E/ubiquinol status as markers of lipid peroxidation in ferrocene iron-loaded rats.
Dresow, B., Albert, C., Zimmermann, I. & Nielsen, P., 1995, In: HEPATOLOGY. 21, 4, p. 1099-1105 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Heterogeneous expression of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase genes in the rat liver lobulus.
Twisk, J., Hoekman, M. F., Mager, W. H., Moorman, A. F., de Boer, P. A., Scheja, L., Princen, H. M. & Gebhardt, R., 1995, In: J CLIN INVEST. 95, 3, p. 1235-1243 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Liver iron stores in patients with secondary haemosiderosis under iron chelation therapy with deferoxamine or deferiprone.
Nielsen, P., Fischer, R., Engelhardt, R., Tondüry, P., Gabbe, E. E. & Janka-Schaub, G., 1995, In: BRIT J HAEMATOL. 91, 4, p. 827-833 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1994
Bioavailability of iron from oral ferric polymaltose in humans.
Nielsen, P., Gabbe, E. E., Fischer, R. & Heinrich, H. C., 1994, In: ARZNEIMITTEL-FORSCH. 44, 6, p. 743-748 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Liver iron quantification: studies in aqueous iron solutions, iron overloaded rats, and patients with hereditary hemochromatosis.
Engelhardt, R., Langkowski, J. H., Fischer, R., Nielsen, P., Kooijman, H., Heinrich, H. C. & Bücheler, E., 1994, In: MAGN RESON IMAGING. 12, 7, p. 999-1007 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pattern of iron storage in the rat heart following iron overloading with trimethylhexanoyl-ferrocene.
Braumann, A., Wulfhekel, U., Nielsen, P., Balkenhol, B. & Düllmann, J., 1994, In: Acta Anat (Basel). 150, 1, p. 45-54 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Screening for hereditary hemochromatosis in prospective blood donors.
Benn, H. P., Nielsen, P., Fischer, R., Schwarz, D., Engelhardt, R., Darda, C., Dittmer, R., Knödler, B., Gabbe, E. E. & Kühnl, P., 1994, In: Beitr Infusionsther Transfusionsmed. 32, p. 314-316Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review