Department of Biochemistry and Molecular Cell Biology

Publications

  1. 2004
  2. Differential RNA interference: replacement of endogenous with recombinant low density lipoprotein receptor-related protein (LRP).

    Laatsch, A., Ragozin, S., Grewal, T., Beisiegel, U. & Joerg, H., 2004, In: EUR J CELL BIOL. 83, 3, p. 113-120 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Impaired recycling of apolipoprotein E4 is associated with intracellular cholesterol accumulation.

    Heeren, J., Grewal, T., Laatsch, A., Becker, N., Rinninger, F., Rye, K-A. & Beisiegel, U., 2004, In: J BIOL CHEM. 279, 53, p. 55483-55492 53.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Interaction of artificial metallic objects with biosusceptometric measurements.

    Engelhardt, R., Fung, E. B., Kelly, P., Biehl, T. R., Pakbaz, Z., Nielsen, P., Harmatz, P. & Fischer, R., 2004, In: Neurol Clin Neurophysiol. 2004, p. 32

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Low dose-ethanol modulates toxic effect of iron-overloading in the liver.

    Beutelspacher, S. C., Serbecic, N., Tan, P. H., Mehrabi, M., Nielsen, P. & Yamane, Y., 2004, In: J NUTR SCI VITAMINOL. 50, 2, p. 78-86 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. 2003
  7. Effective treatment of hereditary haemochromatosis with desferrioxamine in selected cases.

    Nielsen, P., Fischer, R., Buggisch, P. & Janka-Schaub, G., 2003, In: BRIT J HAEMATOL. 123, 5, p. 952-953 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Monitoring long-term efficacy of iron chelation therapy by deferiprone and desferrioxamine in patients with beta-thalassaemia major: application of SQUID biomagnetic liver susceptometry.

    Fischer, R., Longo, F., Nielsen, P., Engelhardt, R., Hider, R. C. & Piga, A., 2003, In: BRIT J HAEMATOL. 121, 6, p. 938-948 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Recycling of apoprotein E is associated with cholesterol efflux and high density lipoprotein internalization.

    Heeren, J., Grewal, T., Laatsch, A., Rottke, D., Rinninger, F., Enrich, C. & Beisiegel, U., 2003, In: J BIOL CHEM. 278, 16, p. 14370-14378 16.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. 2002
  11. Human mesenchymal stem cells are not of donor origin in patients with severe aplastic anemia who underwent sex-mismatched allogeneic bone marrow transplant

    Stute, N., Fehse, B., Schröder, J., Arps, S., Adamietz, P., Held, K. R. & Zander, A. R., 12.2002, In: J HEMATOTH STEM CELL. 11, 6, p. 977-984 8 p.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  12. Characterization of the VPS10 domain of SorLA/LR11 as binding site for the neuropeptide HA.

    Lintzel, J., Franke, I., Riedel, I. B., Schaller, H. C. & Hampe, W., 2002, In: BIOL CHEM. 383, 11, p. 1727-1733 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors.

    Wittenberger, T., Hellebrand, S., Munck, A., Kreienkamp, H-J., Schaller, H. C. & Hampe, W., 2002, In: BMC GENOMICS. 3, 1, p. 17 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Non-invasive liver iron quantification by SQUID-biosusceptometry and serum ferritin iron as new diagnostic parameters in hereditary hemochromatosis.

    Nielsen, P., Engelhardt, R., Düllmann, J. & Fischer, R., 2002, In: BLOOD CELL MOL DIS. 29, 3, p. 451-458 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. [SQUID-biosusceptometry in iron overloaded patients with hematologic diseases]

    Nielsen, P., Kordes, U., Fischer, R., Engelhardt, R. & Janka-Schaub, G., 2002, In: KLIN PADIATR. 214, 4, p. 218-222 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. 2001
  17. Identification of a cis-acting element and a novel trans-acting factor of the glutamine synthetase gene in liver cells.

    Gaunitz, F., Weber, S., Scheja, L. & Gebhardt, R., 2001, In: BIOCHEM BIOPH RES CO. 284, 2, p. 377-383 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Identification of SorCS2, a novel member of the VPS10 domain containing receptor family, prominently expressed in the developing mouse brain.

    Rezgaoui, M., Hermey, G., Riedel, I. B., Hampe, W., Schaller, H. C. & Hermans-Borgmeyer, I., 2001, In: MECH DEVELOP. 100, 2, p. 335-338 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. The genes for the human VPS10 domain-containing receptors are large and contain many small exons.

    Hampe, W., Rezgaoui, M., Hermans-Borgmeyer, I. & Schaller, H. C., 2001, In: HUM GENET. 108, 6, p. 529-536 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. The neuropeptide head activator induces activation and translocation of the growth-factor-regulated Ca(2+)-permeable channel GRC.

    Boels, K., Glassmeier, G., Herrmann, D., Riedel, I. B., Hampe, W., Kojima, I., Schwarz, J. R. & Schaller, H. C., 2001, In: J CELL SCI. 114, 20, p. 3599-3606 20.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. 2000
  22. Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C.

    Wegener, S., Hampe, W., Herrmann, D. & Schaller, H. C., 2000, In: EUR J CELL BIOL. 79, 11, p. 810-815 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Characterisation of receptor-specific TNFalpha functions in adipocyte cell lines lacking type 1 and 2 TNF receptors.

    Sethi, J. K., Xu, H., Uysal, K. T., Wiesbrock, S. M., Scheja, L. & Hotamisligil, G. S., 2000, In: FEBS LETT. 469, 1, p. 77-82 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Ectodomain shedding, translocation and synthesis of SorLA are stimulated by its ligand head activator.

    Hampe, W., Riedel, I. B., Lintzel, J., Bader, C. O., Franke, I. & Schaller, H. C., 2000, In: J CELL SCI. 113, 24, p. 4475-4485 24.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Engineering of a proteolytically stable human beta 2-adrenergic receptor/maltose-binding protein fusion and production of the chimeric protein in Escherichia coli and baculovirus-infected insect cells.

    Hampe, W., Voss, R. H., Haase, W., Boege, F., Michel, H. & Reiländer, H., 2000, In: J BIOTECHNOL. 77, 2-3, p. 219-234 2-3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Impaired plasma antioxidative defense and increased nontransferrin-bound iron during high-dose chemotherapy and radiochemotherapy preceding bone marrow transplantation.

    Dürken, M., Herrnring, C., Finckh, B., Nagel, S., Nielsen, P., Fischer, R., Berger, H. M., Moison, R. M., Pichlmeier, U., Kohlschütter, B., Zander, A. R. & Kohlschütter, A., 2000, In: FREE RADICAL BIO MED. 28, 6, p. 887-894 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Improved glucose and lipid metabolism in genetically obese mice lacking aP2.

    Uysal, K. T., Scheja, L., Wiesbrock, S. M., Bonner-Weir, S. & Hotamisligil, G. S., 2000, In: ENDOCRINOLOGY. 141, 9, p. 3388-3396 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Serum ferritin iron in iron overload and liver damage: correlation to body iron stores and diagnostic relevance.

    Nielsen, P., Günther, U., Dürken, M., Fischer, R. & Düllmann, J., 2000, In: J LAB CLIN MED. 135, 5, p. 413-418 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Using SQUID biomagnetic liver susceptometry in the treatment of thalassemia and other iron loading diseases.

    Nielsen, P., Engelhardt, R., Duerken, M., Janka-Schaub, G. & Fischer, R., 2000, In: Transfus Sci. 23, 3, p. 257-258 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. 1999
  31. A head-activator binding protein is present in hydra in a soluble and a membrane-anchored form.

    Hampe, W., Urny, J., Franke, I., Hoffmeister-Ullerich, S. A., Herrmann, D., Petersen, C. M., Lohmann, J. & Schaller, H. C., 1999, In: DEVELOPMENT. 126, 18, p. 4077-4086 18.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Altered insulin secretion associated with reduced lipolytic efficiency in aP2-/- mice.

    Scheja, L., Makowski, L., Uysal, K. T., Wiesbrock, S. M., Shimshek, D. R., Meyers, D. S., Morgan, M., Parker, R. A. & Hotamisligil, G. S., 1999, In: DIABETES. 48, 10, p. 1987-1994 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Assessment of iron stores in children with transfusion siderosis by biomagnetic liver susceptometry.

    Fischer, R., Tiemann, C. D., Engelhardt, R., Nielsen, P., Dürken, M., Gabbe, E. E. & Janka-Schaub, G., 1999, In: AM J HEMATOL. 60, 4, p. 289-299 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Function of the neuropeptide head activator for early neural and neuroendocrine development.

    Hampe, W., Hermans-Borgmeyer, I. & Schaller, H. C., 1999, In: Results Probl Cell Differ. 26, p. 323-337

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Identification and characterization of SorCS, a third member of a novel receptor family.

    Hermey, G., Riedel, I. B., Hampe, W., Schaller, H. C. & Hermans-Borgmeyer, I., 1999, In: BIOCHEM BIOPH RES CO. 266, 2, p. 347-351 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Long-term survival in a patient with AIDS and hereditary haemochromatosis.

    Nielsen, P., Degen, O., Brümmer, J. & Gabbe, E. E., 1999, In: EUR J HAEMATOL. 63, 3, p. 202-204 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. 1998
  38. Effect of oral iron chelator L1 on iron absorption in man.

    Dresow, B., Fischer, R., Nielsen, P., Gabbe, E. E. & Piga, A., 1998, In: ANN NY ACAD SCI. 850, p. 466-468

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Iron supplementation in athletes. Current recommendations.

    Nielsen, P. & Nachtigall, D., 1998, In: SPORTS MED. 26, 4, p. 207-216 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Liver iron and fibrosis during long-term treatment with deferiprone in Swiss thalassaemic patients.

    Töndury, P., Zimmermann, A., Nielsen, P. & Hirt, A., 1998, In: BRIT J HAEMATOL. 101, 3, p. 413-415 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Non-transferrin bound iron induced by myeloablative therapy.

    Dürken, M., Kohlschütter, A. & Nielsen, P., 1998, In: BRIT J HAEMATOL. 101, 2, p. 393-394 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Prevalence of the C282Y and H63D mutations in the HFE gene in patients with hereditary haemochromatosis and in control subjects from Northern Germany.

    Nielsen, P., Carpinteiro, S., Fischer, R., Cabeda, J. M., Porto, G. & Gabbe, E. E., 1998, In: BRIT J HAEMATOL. 103, 3, p. 842-845 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Unique expression pattern of a novel mosaic receptor in the developing cerebral cortex.

    Hermans-Borgmeyer, I., Hampe, W., Schinke, B., Methner, A., Nykjaer, A., Süsens, U., Fenger, U., Herbarth, B. & Schaller, H. C., 1998, In: MECH DEVELOP. 70, 1-2, p. 65-76 1-2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. 1997
  45. Nontransferrin-bound iron in serum of patients receiving bone marrow transplants.

    Dürken, M., Nielsen, P., Knobel, S., Finckh, B., Herrnring, C., Dresow, B., Kohlschütter, B., Stockschläder, M., Krüger, W. H., Kohlschütter, A. & Zander, A. R., 1997, In: FREE RADICAL BIO MED. 22, 7, p. 1159-1163 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Purification of a head-activator receptor from hydra.

    Franke, I., Buck, F. & Hampe, W., 1997, In: EUR J BIOCHEM. 244, 3, p. 940-945 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Successful treatment of iron overload by phlebotomies in a patient with severe congenital dyserythropoietic anemia type II.

    Hofmann, W. K., Kaltwasser, J. P., Hoelzer, D., Nielsen, P. & Gabbe, E. E., 1997, In: BLOOD. 89, 8, p. 3068-3069 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Treatment of cirrhotic rats with L-ornithine-L-aspartate enhances urea synthesis and lowers serum ammonia levels.

    Gebhardt, R., Beckers, G., Gaunitz, F., Haupt, W., Jonitza, D., Klein, S. & Scheja, L., 1997, In: J PHARMACOL EXP THER. 283, 1, p. 1-6 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. 1996
  50. Pregnancy after intracytoplasmic sperm injection of spermatozoa extracted from frozen-thawed testicular biopsy

    Fischer, R., Baukloh, V., Naether, O. G., Schulze, W., Salzbrunn, A. & Benson, D. M., 10.1996, In: HUM REPROD. 11, 10, p. 2197-9 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Iron deficiency in distance runners. A reinvestigation using Fe-labelling and non-invasive liver iron quantification.

    Nachtigall, D., Nielsen, P., Fischer, R., Engelhardt, R. & Gabbe, E. E., 1996, In: INT J SPORTS MED. 17, 7, p. 473-479 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. Photoaffinity labeling of the head-activator receptor from hydra.

    Hampe, W., Frank, R. W., Schulze, C., Dehning, I. & Schaller, H. C., 1996, In: EUR J BIOCHEM. 235, 3, p. 814-820 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. 1995
  54. Ethane exhalation and vitamin E/ubiquinol status as markers of lipid peroxidation in ferrocene iron-loaded rats.

    Dresow, B., Albert, C., Zimmermann, I. & Nielsen, P., 1995, In: HEPATOLOGY. 21, 4, p. 1099-1105 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  55. Heterogeneous expression of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase genes in the rat liver lobulus.

    Twisk, J., Hoekman, M. F., Mager, W. H., Moorman, A. F., de Boer, P. A., Scheja, L., Princen, H. M. & Gebhardt, R., 1995, In: J CLIN INVEST. 95, 3, p. 1235-1243 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  56. Liver iron stores in patients with secondary haemosiderosis under iron chelation therapy with deferoxamine or deferiprone.

    Nielsen, P., Fischer, R., Engelhardt, R., Tondüry, P., Gabbe, E. E. & Janka-Schaub, G., 1995, In: BRIT J HAEMATOL. 91, 4, p. 827-833 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  57. 1994
  58. Bioavailability of iron from oral ferric polymaltose in humans.

    Nielsen, P., Gabbe, E. E., Fischer, R. & Heinrich, H. C., 1994, In: ARZNEIMITTEL-FORSCH. 44, 6, p. 743-748 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  59. Liver iron quantification: studies in aqueous iron solutions, iron overloaded rats, and patients with hereditary hemochromatosis.

    Engelhardt, R., Langkowski, J. H., Fischer, R., Nielsen, P., Kooijman, H., Heinrich, H. C. & Bücheler, E., 1994, In: MAGN RESON IMAGING. 12, 7, p. 999-1007 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  60. Pattern of iron storage in the rat heart following iron overloading with trimethylhexanoyl-ferrocene.

    Braumann, A., Wulfhekel, U., Nielsen, P., Balkenhol, B. & Düllmann, J., 1994, In: Acta Anat (Basel). 150, 1, p. 45-54 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  61. Screening for hereditary hemochromatosis in prospective blood donors.

    Benn, H. P., Nielsen, P., Fischer, R., Schwarz, D., Engelhardt, R., Darda, C., Dittmer, R., Knödler, B., Gabbe, E. E. & Kühnl, P., 1994, In: Beitr Infusionsther Transfusionsmed. 32, p. 314-316

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review