II. Department of Medicine

Publications

  1. 2012
  2. Palliative und supportive Therapie beim Karzinom des ösophagogastralen Übergangs

    Block, A. & Arnold, D., 2012, In: VISZERALMEDIZIN. 28, 2, p. 121-127 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Peroxiredoxins 3 and 4 are overexpressed in prostate cancer tissue and affect the proliferation of prostate cancer cells in vitro.

    Ummanni, R., Barreto, F., Venz, S., Scharf, C., Barett, C., Mannsperger, H. A., Brase, J. C., Kuner, R., Schlomm, T., Sauter, G., Sültmann, H., Korf, U., Bokemeyer, C., Walther, R., Brümmendorf, T. & Balabanov, S., 2012, In: J PROTEOME RES. 11, 4, p. 2452-2466 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Personalized treatment of colorectal cancer.

    Arnold, D. & Stein, A., 2012, In: ONKOLOGIE. 35 Suppl 1, p. 42-48

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Phenotypic detection of clonotypic B cells in multiple myeloma by specific immunoglobulin ligands reveals their rarity in multiple myeloma.

    Trepel, M., Martens, V., Doll, C., Rahlff, J., Gösch, B., Loges, S. & Binder, M., 2012, In: PLOS ONE. 7, 2, p. 31998 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Polymorphism Thr160Thr in SRD5A1, involved in the progesterone metabolism, modifies postmenopausal breast cancer risk associated with menopausal hormone therapy.

    Hein, R., Abbas, S., Seibold, P., Salazar, R., Flesch-Janys, D. & Chang-Claude, J., 2012, In: BREAST CANCER RES TR. 131, 2, p. 653-661 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Pre-diagnostic alcohol consumption and postmenopausal breast cancer survival: a prospective patient cohort study.

    Vrieling, A., Buck, K., Heinz, J., Obi, N., Benner, A., Flesch-Janys, D. & Chang-Claude, J., 2012, In: BREAST CANCER RES TR. 136, 1, p. 195-207 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Preliminary data of a HAMD-17 validated symptom scale derived from the ICD-10 to diagnose depression in outpatients

    Melzer, J., Rostock, M., Brignoli, R., Keck, M. E. & Saller, R., 2012, In: FORSCH KOMPLEMENTMED. 19, 4, p. 191-6 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Progression free survival of first line vascular endothelial growth factor-targeted therapy is an important prognostic parameter in patients with metastatic renal cell carcinoma.

    Seidel, C., Busch, J., Weikert, S., Steffens, S., Fenner, M., Ganser, A. & Grünwald, V., 2012, In: EUR J CANCER. 48, 7, p. 1023-1030 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Prospective study of rabbit antithymocyte globulin and cyclosporine for aplastic anemia from the EBMT Severe Aplastic Anaemia Working Party.

    Marsh, J. C., Bacigalupo, A., Schrezenmeier, H., Tichelli, A., Risitano, A. M., Passweg, J. R., Killick, S. B., Warren, A. J., Foukaneli, T., Aljurf, M., Al-Zahrani, H. A., Schafhausen, P., Roth, A., Franzke, A., Brummendorf, T. H., Dufour, C., Oneto, R., Sedgwick, P., Barrois, A., Kordasti, S., Elebute, M. O., Mufti, G. J., Socie, G., Blood, E. & Party, M. T. G. S. A. A. W., 2012, In: BLOOD. 119, 23, p. 5391-5396 23.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Protein-protein-interaction network organization of the hypusine modification system.

    Sievert, H., Venz, S., Platas-Barradas, O., Dhople, V. M., Schaletzky, M., Nagel, C-H., Balabanov, M., Preukschas, M., Pällmann, N., Bokemeyer, C., Brümmendorf, T., Pörtner, R., Walther, R., Duncan, K. E., Hauber, J. & Balabanov, S., 2012, In: MOL CELL PROTEOMICS. 11, 11, p. 1289-1305 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Proteomic profiling of germ cell cancer cells treated with aaptamine, a marine alkaloid with antiproliferative activity.

    Dyshlovoy, S. A., Naeth, I., Venz, S., Preukschas, M., Sievert, H., Jacobsen, C., Shubina, L. K., Manuela, G. S., Scharf, C., Walther, R., Krepstakies, M., Priyadarshini, P., Hauber, J., Fedorov, S. N., Bokemeyer, C., Stonik, V. A., Balabanov, S. & Honecker, F., 2012, In: J PROTEOME RES. 11, 4, p. 2316-2330 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. PTEN deletion is rare but often homogeneous in gastric cancer.

    Mina, S., Bohn, B., Simon, R., Krohn, A., Reeh, M., Arnold, D., Bokemeyer, C., Sauter, G., Izbicki, J. R., Marx, A. & Stahl, P., 2012, In: J CLIN PATHOL. 65, 8, p. 693-698 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: a multicenter international myeloma working group study.

    Kumar, S. K., Lee, J. H., Lahuerta, J. J., Morgan, G., Richardson, P. G., Crowley, J., Haessler, J., Feather, J., Hoering, A., Moreau, P., LeLeu, X., Hulin, C., Klein, S. K., Sonneveld, P., Siegel, D., Bladé, J., Goldschmidt, H., Jagannath, S., Miguel, J. S., Orlowski, R., Palumbo, A., Sezer, O., Rajkumar, S. V., Durie, B. G. M. & Group, I. M. W., 2012, In: LEUKEMIA. 26, 1, p. 149-157 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Role of interleukin 16 in multiple myeloma.

    Atanackovic, D., Hildebrandt, Y., Templin, J., Cao, Y., Keller, C., Panse, J., Meyer, S., Reinhard, H., Bartels, K., Lajmi, N., Sezer, O., Zander, A. R., Marx, A., Uhlig, R., Zustin, J., Bokemeyer, C. & Kröger, N., 2012, In: JNCI-J NATL CANCER I. 104, 13, p. 1005-1020 13.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Safety and efficacy of exercise training in various forms of pulmonary hypertension.

    Grünig, E., Lichtblau, M., Ehlken, N., Ghofrani, H. A., Reichenberger, F., Staehler, G., Halank, M., Fischer, C., Seyfarth, H-J., Klose, H., Meyer, A., Sorichter, S., Wilkens, H., Rosenkranz, S., Opitz, C., Leuchte, H., Karger, G., Speich, R. & Nagel, C., 2012, In: EUR RESPIR J. 40, 1, p. 84-92 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Similar incidences of TP53 deletions in extramedullary organ infiltrations, soft tissue and osteolyses of patients with multiple myeloma.

    Billecke, L., Murga-Penas, E-M., May, A. M., Engelhardt, M., Nagler, A., Leiba, M., Schiby, G., Kröger, N., Zustin, J., Marx, A., Matschke, J., Tiemann, M., Goekkurt, E., Bokemeyer, C. & Schilling, G., 2012, In: ANTICANCER RES. 32, 5, p. 2031-2034 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Successful eradication of a FVIII inhibitor in a 60-year-old patient with mild haemophilia A using single-agent prednisolone.

    Holstein, K., Marx, G., Lentz, B., Bokemeyer, C. & Langer, F., 2012, In: HAMOSTASEOLOGIE. 32 Suppl 1, p. 48-51

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Succinate reverses in-vitro platelet inhibition by acetylsalicylic acid and P2Y receptor antagonists.

    Spath, B., Hansen, A., Bokemeyer, C. & Langer, F., 2012, In: PLATELETS. 23, 1, p. 60-68 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Targeting aurora kinases with danusertib (PHA-739358) inhibits growth of liver metastases from gastroenteropancreatic neuroendocrine tumors in an orthotopic xenograft model.

    Fraedrich, K., Schrader, J., Ittrich, H., von Amsberg, G., Gontarewicz, A., Matzat, V., Kromminga, A., Pace, A., Moll, J., Bläker, M., Lohse, A. W., Hörsch, D., Brümmendorf, T. & Benten, D., 2012, In: CLIN CANCER RES. 18, 17, p. 4621-4632 17.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Targeting Epithelial Growth Factor Receptor (EGFR) With Cetuximab in Combination With Irinotecan as Salvage Treatment in Refractory Gastric Cancer Patients: A Retrospective Analysis and Review of the Literature

    Stein, A., Peinert, S., Al-Batran, S-E. & Arnold, D., 2012, In: Eur J Clin Med Oncol. 4, 1, p. 11-17 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Telomere elongation and clinical response to androgen treatment in a patient with aplastic anemia and a heterozygous hTERT gene mutation.

    Ziegler, P., Schrezenmeier, H., Akkad, J., Brassat, U., Vankann, L., Panse, J., Wilop, S., Balabanov, S., Schwarz, K., Martens, U. M. & Brümmendorf, T. H., 2012, In: ANN HEMATOL. 91, 7, p. 1115-1120 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. The impact of a specific aqua-training for adult haemophilic patients--results of the WATERCISE study (WAT-QoL).

    Mackensen von, S., Eifrig, B., Zäch, D., Kalnins, J., Wieloch, A. & Zeller, W., 2012, In: HAEMOPHILIA. 18, 5, p. 714-721 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. The metabolite 3-hydroxiglutaric acid effectively reduces glioblastoma growth in vivo by affecting the structural integrity of tumor vasculature.

    Oliveira-Ferrer, L., Wellbrock, J., Balabanov, M., Klockow, M., Hauschild, J., Bokemeyer, C., Fiedler, W., Ergun, S. & Schuch, G., 2012, In: CANCER LETT. 326, 2, p. 161-167 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. The novel, orally bioavailable HSP90 inhibitor NVP-HSP990 induces cell cycle arrest and apoptosis in multiple myeloma cells and acts synergistically with melphalan by increased cleavage of caspases.

    Lamottke, B., Kaiser, M., Mieth, M., Heider, U., Gao, Z., Nikolova, Z., Jensen, M. R., Sterz, J., von Metzler, I. & Sezer, O., 2012, In: EUR J HAEMATOL. 88, 5, p. 406-415 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. The role of regulatory T cells and TH17 cells in multiple myeloma.

    Braga, W. M. T., Atanackovic, D. & Colleoni, G. W. B., 2012, In: Clin Dev Immunol. 2012, p. 293479

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. [Tracheal metastasis of a cutaneous malignant melanoma].

    Ritzel, R. M., Klose, H. & Habermann, C., 2012, In: ROFO-FORTSCHR RONTG. 184, 8, p. 742-743 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Transfusion risk in cancer patients with chemotherapy-induced anemia when initiating darbepoetin alfa therapy at a baseline hemoglobin level of <9 g/dL versus 9 to <10 g/dL versus ≥ 10 g/dL: an exploratory analysis of a phase 3 trial.

    Canon, J-L., Vansteenkiste, J., Hedenus, M., Gascon, P., Bokemeyer, C., Ludwig, H., Vermorken, J., Legg, J., Pujol, B. & Bridges, K., 2012, In: MED ONCOL. 29, 3, p. 2291-2299 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature.

    Stein, A., Glockzin, G., Wienke, A., Arnold, D., Edelmann, T., Hildebrandt, B., Hollerbach, S., Illerhaus, G., Königsrainer, A., Richter, M., Schlitt, H. J. & Schmoll, H-J., 2012, In: BMC CANCER. 12, p. 356

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Tumorerfassung

    Frenzel, T., Honecker, F., Krüll, A., Petersen, C. & Yekebas, E. F., 2012, Tumorerfassung: mit Erfassungsbögen und Leitlinien für die interdiszipl. Diagnostik und Therapie. Thieme-Verlag Stuttgart, p. 1-328 328 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  31. Umsetzung integrativer Konzepte - eine Bestandsaufnahme

    Horneber, M., Overkamp, F. & Rostock, M., 2012, In: ONKOLOGIE. 35 Suppl 5, p. 3-11 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Validation of CRP as prognostic marker for renal cell carcinoma in a large series of patients.

    Steffens, S., Köhler, A., Rudolph, R., Eggers, H., Seidel, C., Janssen, M., Wegener, G., Schrader, M., Kuczyk, M. A. & Schrader, A. J., 2012, In: BMC CANCER. 12, p. 399

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. 2011
  34. Characterization of Enterobacter cloacae pneumonia: a single-center retrospective analysis.

    Hennigs, J. K., Baumann, H. J., Schmiedel, S., Tennstedt, P., Sobottka, I., Bokemeyer, C., Kluge, S. & Klose, H., 01.12.2011, In: LUNG. 189, 6, p. 475-483 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Preclinical and clinical activity of sunitinib in patients with cisplatin-refractory or multiply relapsed germ cell tumors: a Canadian Urologic Oncology Group/German Testicular Cancer Study Group cooperative study

    Oechsle, K., Honecker, F., Cheng, T., Mayer, F., Czaykowski, P., Winquist, E., Wood, L., Fenner, M., Glaesener, S., Hartmann, J. T., Chi, K., Bokemeyer, C. & Kollmannsberger, C., 01.12.2011, In: ANN ONCOL. 22, 12, p. 2654-60 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Sequence therapy in patients with metastatic renal cell carcinoma: comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors

    Busch, J., Seidel, C., Kempkensteffen, C., Johannsen, M., Wolff, I., Hinz, S., Magheli, A., Miller, K., Grünwald, V. & Weikert, S., 12.2011, In: EUR UROL. 60, 6, p. 1163-70 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Klassifikation und Differentialdiagnose der pulmonalen Hypertonie

    Hennigs, J. K., Baumann, H. J., Lüneburg, N., Kluge, S., Sydow, K. & Klose, H., 01.11.2011, In: Atemwegs LungenKh. 37, p. 443-448 5 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  38. Modern imaging techniques during therapy in patients with multiple myeloma

    Horger, M., Weisel, K., Bares, R., Ernemann, U., Claussen, C. D., Lichy, M. & Fenchel, M., 01.10.2011, In: ACTA RADIOL. 52, 8, p. 881-8 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  39. Efficient synthesis and applications of peptides containing adenylylated tyrosine residues

    Smit, C., Blümer, J., Eerland, M. F., Albers, M. F., Goody, R. S., Itzen, A. & Hedberg, C., 19.09.2011, In: ANGEW CHEM INT EDIT. 50, 39, p. 9200-4 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. EAU guidelines on testicular cancer: 2011 update

    Albers, P., Albrecht, W., Algaba, F., Bokemeyer, C., Cohn-Cedermark, G., Fizazi, K., Horwich, A., Laguna, M. P. & European Association of Urology, 01.08.2011, In: EUR UROL. 60, 2, p. 304-319 16 p., 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Final results of the European Advanced Renal Cell Carcinoma Sorafenib (EU-ARCCS) expanded-access study: a large open-label study in diverse community settings.

    Beck, J., Procopio, G., Bajetta, E., Keilholz, U., Negrier, S., Szczylik, C., Bokemeyer, C., Bracarda, S., Richel, D. J., Staehler, M., Strauss, U. P., Mersmann, S., Burock, K. & Escudier, B., 01.08.2011, In: ANN ONCOL. 22, 8, p. 1812-1823 12 p., 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Treatment of patients with relapsed and/or cisplatin-refractory metastatic germ cell tumours: an update.

    Koychev, D., Oechsle, K., Bokemeyer, C. & Honecker, F., 01.08.2011, In: INT J ANDROL. 34, 4 Pt 2, p. 266-273 4 Pt 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Response of renal lesions during systemic treatment with sunitinib in patients with metastatic renal cell carcinoma: a single center experience with 14 patients

    Seidel, C., Fenner, M., Merseburger, A. S., Reuter, C., Ivanyi, P., Länger, F., Ganser, A. & Grünwald, V., 06.2011, In: WORLD J UROL. 29, 3, p. 355-60 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Actual and predicted survival time of patients with spinal metastases of lung cancer: evaluation of the robustness of the Tokuhashi score.

    Hessler, C., Vettorazzi, E., Madert, J., Bokemeyer, C. & Panse, J., 20.05.2011, In: SPINE. 36, 12, p. 983-989 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells

    Nilsson, S., Huelsenbeck, J. & Fritz, G., 01.05.2011, In: CANCER LETT. 304, 1, p. 60-9 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Einsatz von mTOR-Inhibitoren bei soliden Tumoren

    Seidel, C. & Grünwald, V., 04.2011, In: Med Monatsschr Pharm. 34, 4, p. 116-26; quiz 127-8

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Purification of CD4+ T cells for adoptive immunotherapy after allogeneic hematopoietic stem cell transplantation

    Klyuchnikov, E., Sputtek, A., Slesarchuk, O., Lioznov, M., Stübig, T., Bacher, U., Amtsfeld, G., Merle, E., Reckhaus, M-L., Fehse, B., Wolschke, C., Adjalle, R., Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 01.03.2011, In: BIOL BLOOD MARROW TR. 17, 3, p. 374-383 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Limited clinical relevance of imaging techniques in the follow-up of patients with advanced chronic lymphocytic leukemia: results of a meta-analysis

    Eichhorst, B. F., Fischer, K., Fink, A-M., Elter, T., Wendtner, C. M., Goede, V., Bergmann, M., Stilgenbauer, S., Hopfinger, G., Ritgen, M., Bahlo, J., Busch, R., Hallek, M., German CLL Study Group (GCLLSG) & Bokemeyer, C., 10.02.2011, In: BLOOD. 117, 6, p. 1817-21 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Expression of TGF-β receptor ALK-5 has a negative impact on outcome of patients with acute myeloid leukemia

    Otten, J., Schmitz, L., Vettorazzi, E., Schultze, A., Marx, A. H., Simon, R., Krauter, J., Loges, S., Sauter, G., Bokemeyer, C. & Fiedler, W., 01.02.2011, In: LEUKEMIA. 25, 2, p. 375-9 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Classical homeopathy in the treatment of cancer patients - a prospective observational study of two independent cohorts

    Rostock, M., Naumann, J., Guethlin, C., Guenther, L., Bartsch, H. H. & Walach, H., 17.01.2011, In: BMC CANCER. 11, p. 19

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Miliary never-smoking adenocarcinoma of the lung: strong association with epidermal growth factor receptor exon 19 deletion.

    Laack, E., Simon, R., Regier, M., Andritzky, B., Tennstedt, P., Habermann, C., Verth, C. Z., Thoem, I., Grob, T., Sauter, G. & Bokemeyer, C., 01.01.2011, In: J THORAC ONCOL. 6, 1, p. 199-202 4 p., 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. The versatile Legionella effector protein DrrA

    Goody, R. S., Schoebel, S., Oesterlin, L. K., Blümer, J., Peters, H., Blankenfeldt, W. & Itzen, A., 01.2011, In: Commun Integr Biol. 4, 1, p. 72-4 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review