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Web based scoring is useful for validation and harmonisation of scoring criteria within RENEB

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Web based scoring is useful for validation and harmonisation of scoring criteria within RENEB. / Romm, Horst; Ainsbury, Elizabeth A; Barquinero, Joan Francesc; Barrios, Leonardo; Beinke, Christina; Cucu, Alexandra; Domene, Mercedes Moreno; Filippi, Silvia; Monteiro Gil, Octávia; Gregoire, Eric; Hadjidekova, Valeria; Hatzi, Vasia; Lindholm, Carita; M Kacher, Radhia; Montoro, Alegria; Moquet, Jayne; Noditi, Mihaela; Oestreicher, Ursula; Palitti, Fabrizio; Pantelias, Gabriel; Prieto, María Jesús; Popescu, Irina; Rothkamm, Kai; Sebastià, Natividad; Sommer, Sylwester; Terzoudi, Georgia; Testa, Antonella; Wojcik, Andrzej.

In: INT J RADIAT BIOL, Vol. 93, No. 1, 22.08.2016, p. 110-117.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Romm, H, Ainsbury, EA, Barquinero, JF, Barrios, L, Beinke, C, Cucu, A, Domene, MM, Filippi, S, Monteiro Gil, O, Gregoire, E, Hadjidekova, V, Hatzi, V, Lindholm, C, M Kacher, R, Montoro, A, Moquet, J, Noditi, M, Oestreicher, U, Palitti, F, Pantelias, G, Prieto, MJ, Popescu, I, Rothkamm, K, Sebastià, N, Sommer, S, Terzoudi, G, Testa, A & Wojcik, A 2016, 'Web based scoring is useful for validation and harmonisation of scoring criteria within RENEB', INT J RADIAT BIOL, vol. 93, no. 1, pp. 110-117. https://doi.org/10.1080/09553002.2016.1206228

APA

Romm, H., Ainsbury, E. A., Barquinero, J. F., Barrios, L., Beinke, C., Cucu, A., Domene, M. M., Filippi, S., Monteiro Gil, O., Gregoire, E., Hadjidekova, V., Hatzi, V., Lindholm, C., M Kacher, R., Montoro, A., Moquet, J., Noditi, M., Oestreicher, U., Palitti, F., ... Wojcik, A. (2016). Web based scoring is useful for validation and harmonisation of scoring criteria within RENEB. INT J RADIAT BIOL, 93(1), 110-117. https://doi.org/10.1080/09553002.2016.1206228

Vancouver

Romm H, Ainsbury EA, Barquinero JF, Barrios L, Beinke C, Cucu A et al. Web based scoring is useful for validation and harmonisation of scoring criteria within RENEB. INT J RADIAT BIOL. 2016 Aug 22;93(1):110-117. https://doi.org/10.1080/09553002.2016.1206228

Bibtex

@article{96d7f9b3a91a4609a7a7ffec028f6ee6,
title = "Web based scoring is useful for validation and harmonisation of scoring criteria within RENEB",
abstract = "PURPOSE: To establish a training data set of digital images and to investigate the scoring criteria and dose assessment of the dicentric assay within the European network of biodosimetry (RENEB), a web based scoring inter-comparison was undertaken by 17 RENEB partners.MATERIALS AND METHODS: Two sets of 50 high resolution images were uploaded onto the RENEB website. One set included metaphases after a moderate exposure (1.3 Gy) and the other set consisted of metaphases after a high dose exposure (3.5 Gy). The laboratories used their own calibration curves for estimating doses based on observed aberration frequencies.RESULTS: The dose estimations and 95% confidence limits were compared to the actual doses and the corresponding z-values were satisfactory for the majority; only the dose estimations from two laboratories were too low or too high. The coefficients of variation were 17.6% for the moderate and 11.2% for the high dose. Metaphases with controversial results could be identified for training purposes.CONCLUSIONS: Overall, the web based scoring of the two galleries by the 17 laboratories produced very good results. Application of web based scoring for the dicentric assay may therefore be a relevant strategy for an operational biodosimetry assistance network.",
author = "Horst Romm and Ainsbury, {Elizabeth A} and Barquinero, {Joan Francesc} and Leonardo Barrios and Christina Beinke and Alexandra Cucu and Domene, {Mercedes Moreno} and Silvia Filippi and {Monteiro Gil}, Oct{\'a}via and Eric Gregoire and Valeria Hadjidekova and Vasia Hatzi and Carita Lindholm and {M Kacher}, Radhia and Alegria Montoro and Jayne Moquet and Mihaela Noditi and Ursula Oestreicher and Fabrizio Palitti and Gabriel Pantelias and Prieto, {Mar{\'i}a Jes{\'u}s} and Irina Popescu and Kai Rothkamm and Natividad Sebasti{\`a} and Sylwester Sommer and Georgia Terzoudi and Antonella Testa and Andrzej Wojcik",
year = "2016",
month = aug,
day = "22",
doi = "10.1080/09553002.2016.1206228",
language = "English",
volume = "93",
pages = "110--117",
journal = "INT J RADIAT BIOL",
issn = "0955-3002",
publisher = "Taylor & Francis",
number = "1",

}

RIS

TY - JOUR

T1 - Web based scoring is useful for validation and harmonisation of scoring criteria within RENEB

AU - Romm, Horst

AU - Ainsbury, Elizabeth A

AU - Barquinero, Joan Francesc

AU - Barrios, Leonardo

AU - Beinke, Christina

AU - Cucu, Alexandra

AU - Domene, Mercedes Moreno

AU - Filippi, Silvia

AU - Monteiro Gil, Octávia

AU - Gregoire, Eric

AU - Hadjidekova, Valeria

AU - Hatzi, Vasia

AU - Lindholm, Carita

AU - M Kacher, Radhia

AU - Montoro, Alegria

AU - Moquet, Jayne

AU - Noditi, Mihaela

AU - Oestreicher, Ursula

AU - Palitti, Fabrizio

AU - Pantelias, Gabriel

AU - Prieto, María Jesús

AU - Popescu, Irina

AU - Rothkamm, Kai

AU - Sebastià, Natividad

AU - Sommer, Sylwester

AU - Terzoudi, Georgia

AU - Testa, Antonella

AU - Wojcik, Andrzej

PY - 2016/8/22

Y1 - 2016/8/22

N2 - PURPOSE: To establish a training data set of digital images and to investigate the scoring criteria and dose assessment of the dicentric assay within the European network of biodosimetry (RENEB), a web based scoring inter-comparison was undertaken by 17 RENEB partners.MATERIALS AND METHODS: Two sets of 50 high resolution images were uploaded onto the RENEB website. One set included metaphases after a moderate exposure (1.3 Gy) and the other set consisted of metaphases after a high dose exposure (3.5 Gy). The laboratories used their own calibration curves for estimating doses based on observed aberration frequencies.RESULTS: The dose estimations and 95% confidence limits were compared to the actual doses and the corresponding z-values were satisfactory for the majority; only the dose estimations from two laboratories were too low or too high. The coefficients of variation were 17.6% for the moderate and 11.2% for the high dose. Metaphases with controversial results could be identified for training purposes.CONCLUSIONS: Overall, the web based scoring of the two galleries by the 17 laboratories produced very good results. Application of web based scoring for the dicentric assay may therefore be a relevant strategy for an operational biodosimetry assistance network.

AB - PURPOSE: To establish a training data set of digital images and to investigate the scoring criteria and dose assessment of the dicentric assay within the European network of biodosimetry (RENEB), a web based scoring inter-comparison was undertaken by 17 RENEB partners.MATERIALS AND METHODS: Two sets of 50 high resolution images were uploaded onto the RENEB website. One set included metaphases after a moderate exposure (1.3 Gy) and the other set consisted of metaphases after a high dose exposure (3.5 Gy). The laboratories used their own calibration curves for estimating doses based on observed aberration frequencies.RESULTS: The dose estimations and 95% confidence limits were compared to the actual doses and the corresponding z-values were satisfactory for the majority; only the dose estimations from two laboratories were too low or too high. The coefficients of variation were 17.6% for the moderate and 11.2% for the high dose. Metaphases with controversial results could be identified for training purposes.CONCLUSIONS: Overall, the web based scoring of the two galleries by the 17 laboratories produced very good results. Application of web based scoring for the dicentric assay may therefore be a relevant strategy for an operational biodosimetry assistance network.

U2 - 10.1080/09553002.2016.1206228

DO - 10.1080/09553002.2016.1206228

M3 - SCORING: Journal article

C2 - 27547893

VL - 93

SP - 110

EP - 117

JO - INT J RADIAT BIOL

JF - INT J RADIAT BIOL

SN - 0955-3002

IS - 1

ER -