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Two new asterosaponins, archasterosides A and B, from the Vietnamese starfish Archaster typicus and their anticancer properties

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Two new asterosaponins, archasterosides A and B, from the Vietnamese starfish Archaster typicus and their anticancer properties. / Kicha, Alla A.; Ivanchina, Natalia V.; Huong, Trinh T.T.; Kalinovsky, Anatoly I.; Dmitrenok, Pavel S.; Fedorov, Sergey N.; Dyshlovoy, Sergey A.; Long, Pham Q.; Stonik, Valentin A.

In: Bioorganic and Medicinal Chemistry Letters, Vol. 20, No. 12, 2010, p. 3826-3830.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Kicha, AA, Ivanchina, NV, Huong, TTT, Kalinovsky, AI, Dmitrenok, PS, Fedorov, SN, Dyshlovoy, SA, Long, PQ & Stonik, VA 2010, 'Two new asterosaponins, archasterosides A and B, from the Vietnamese starfish Archaster typicus and their anticancer properties', Bioorganic and Medicinal Chemistry Letters, vol. 20, no. 12, pp. 3826-3830. https://doi.org/10.1016/j.bmcl.2010.04.005

APA

Kicha, A. A., Ivanchina, N. V., Huong, T. T. T., Kalinovsky, A. I., Dmitrenok, P. S., Fedorov, S. N., Dyshlovoy, S. A., Long, P. Q., & Stonik, V. A. (2010). Two new asterosaponins, archasterosides A and B, from the Vietnamese starfish Archaster typicus and their anticancer properties. Bioorganic and Medicinal Chemistry Letters, 20(12), 3826-3830. https://doi.org/10.1016/j.bmcl.2010.04.005

Vancouver

Kicha AA, Ivanchina NV, Huong TTT, Kalinovsky AI, Dmitrenok PS, Fedorov SN et al. Two new asterosaponins, archasterosides A and B, from the Vietnamese starfish Archaster typicus and their anticancer properties. Bioorganic and Medicinal Chemistry Letters. 2010;20(12):3826-3830. https://doi.org/10.1016/j.bmcl.2010.04.005

Bibtex

@article{3719812436cc42b0bb4e61f833f3f01e,
title = "Two new asterosaponins, archasterosides A and B, from the Vietnamese starfish Archaster typicus and their anticancer properties",
abstract = "New asterosaponins archasterosides A (1), B (2), and the known regularoside A (3) were isolated from the Vietnamese starfish Archaster typicus and structurally elucidated by extensive NMR techniques and chemical transformations. Compounds 1-3 showed moderate cytotoxic activities against HeLa and mouse JB6 P+ Cl41 cell lines. The most active, 2, induced basal AP-1- and p53-, but not NF-κB-transcriptional activations in JB6 Cl41 cells.",
keywords = "Archaster typicus, Asterosaponins, Cytotoxic activity, Glycosides, NMR spectra, Starfish, Steroidal aglycons, Sulfates",
author = "Kicha, {Alla A.} and Ivanchina, {Natalia V.} and Huong, {Trinh T.T.} and Kalinovsky, {Anatoly I.} and Dmitrenok, {Pavel S.} and Fedorov, {Sergey N.} and Dyshlovoy, {Sergey A.} and Long, {Pham Q.} and Stonik, {Valentin A.}",
note = "Funding Information: Financial support was provided by Program of RAS {\textquoteleft}Molecular and Cell Biology{\textquoteright} (MCB RAS) , Grant 09-04-90308-Viet_a from the RFBR , the Vietnam 01-672/QD-KHCNVN Project, FEB RAS Grants 10-III-B-05-018 , 09-III-A-05-146 . The authors are grateful to Dr. Do Cong Thung, VAST, for the identification of the starfish. Copyright: Copyright 2010 Elsevier B.V., All rights reserved.",
year = "2010",
doi = "10.1016/j.bmcl.2010.04.005",
language = "English",
volume = "20",
pages = "3826--3830",
number = "12",

}

RIS

TY - JOUR

T1 - Two new asterosaponins, archasterosides A and B, from the Vietnamese starfish Archaster typicus and their anticancer properties

AU - Kicha, Alla A.

AU - Ivanchina, Natalia V.

AU - Huong, Trinh T.T.

AU - Kalinovsky, Anatoly I.

AU - Dmitrenok, Pavel S.

AU - Fedorov, Sergey N.

AU - Dyshlovoy, Sergey A.

AU - Long, Pham Q.

AU - Stonik, Valentin A.

N1 - Funding Information: Financial support was provided by Program of RAS ‘Molecular and Cell Biology’ (MCB RAS) , Grant 09-04-90308-Viet_a from the RFBR , the Vietnam 01-672/QD-KHCNVN Project, FEB RAS Grants 10-III-B-05-018 , 09-III-A-05-146 . The authors are grateful to Dr. Do Cong Thung, VAST, for the identification of the starfish. Copyright: Copyright 2010 Elsevier B.V., All rights reserved.

PY - 2010

Y1 - 2010

N2 - New asterosaponins archasterosides A (1), B (2), and the known regularoside A (3) were isolated from the Vietnamese starfish Archaster typicus and structurally elucidated by extensive NMR techniques and chemical transformations. Compounds 1-3 showed moderate cytotoxic activities against HeLa and mouse JB6 P+ Cl41 cell lines. The most active, 2, induced basal AP-1- and p53-, but not NF-κB-transcriptional activations in JB6 Cl41 cells.

AB - New asterosaponins archasterosides A (1), B (2), and the known regularoside A (3) were isolated from the Vietnamese starfish Archaster typicus and structurally elucidated by extensive NMR techniques and chemical transformations. Compounds 1-3 showed moderate cytotoxic activities against HeLa and mouse JB6 P+ Cl41 cell lines. The most active, 2, induced basal AP-1- and p53-, but not NF-κB-transcriptional activations in JB6 Cl41 cells.

KW - Archaster typicus

KW - Asterosaponins

KW - Cytotoxic activity

KW - Glycosides

KW - NMR spectra

KW - Starfish

KW - Steroidal aglycons

KW - Sulfates

UR - http://www.scopus.com/inward/record.url?scp=77954213153&partnerID=8YFLogxK

U2 - 10.1016/j.bmcl.2010.04.005

DO - 10.1016/j.bmcl.2010.04.005

M3 - SCORING: Journal article

C2 - 20493687

AN - SCOPUS:77954213153

VL - 20

SP - 3826

EP - 3830

IS - 12

ER -