Temporal control of immediate early gene induction by light.

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Temporal control of immediate early gene induction by light. / Schoenenberger, Philipp; Gerosa, Daniela; Oertner, Thomas G.

In: PLOS ONE, Vol. 4, No. 12, 12, 2009, p. 8185.

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@article{cd7c7a239bac4666b8f767e352e7046e,
title = "Temporal control of immediate early gene induction by light.",
abstract = "The light-gated cation channel channelrhodopsin-2 (ChR2) is a powerful tool for the optical induction of action potentials in neurons. Mutations of the cysteine 128 (C128) residue have been shown to greatly extend the lifetime of the conducting state of ChR2. However, until now, only subthreshold depolarizations have been reported from C128 mutants.",
keywords = "Animals, Time Factors, Mice, Rats, *Light, Action Potentials/radiation effects, Cell Adhesion/radiation effects, Gene Expression Regulation/*radiation effects, Genes, Immediate-Early/*genetics, Ion Channel Gating/radiation effects, Mutation/genetics, Organ Specificity/radiation effects, Proto-Oncogene Proteins c-fos/genetics/metabolism, Pyramidal Cells/cytology/metabolism/radiation effects, Rhodopsin/genetics, Animals, Time Factors, Mice, Rats, *Light, Action Potentials/radiation effects, Cell Adhesion/radiation effects, Gene Expression Regulation/*radiation effects, Genes, Immediate-Early/*genetics, Ion Channel Gating/radiation effects, Mutation/genetics, Organ Specificity/radiation effects, Proto-Oncogene Proteins c-fos/genetics/metabolism, Pyramidal Cells/cytology/metabolism/radiation effects, Rhodopsin/genetics",
author = "Philipp Schoenenberger and Daniela Gerosa and Oertner, {Thomas G.}",
year = "2009",
language = "English",
volume = "4",
pages = "8185",
journal = "PLOS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "12",

}

RIS

TY - JOUR

T1 - Temporal control of immediate early gene induction by light.

AU - Schoenenberger, Philipp

AU - Gerosa, Daniela

AU - Oertner, Thomas G.

PY - 2009

Y1 - 2009

N2 - The light-gated cation channel channelrhodopsin-2 (ChR2) is a powerful tool for the optical induction of action potentials in neurons. Mutations of the cysteine 128 (C128) residue have been shown to greatly extend the lifetime of the conducting state of ChR2. However, until now, only subthreshold depolarizations have been reported from C128 mutants.

AB - The light-gated cation channel channelrhodopsin-2 (ChR2) is a powerful tool for the optical induction of action potentials in neurons. Mutations of the cysteine 128 (C128) residue have been shown to greatly extend the lifetime of the conducting state of ChR2. However, until now, only subthreshold depolarizations have been reported from C128 mutants.

KW - Animals

KW - Time Factors

KW - Mice

KW - Rats

KW - Light

KW - Action Potentials/radiation effects

KW - Cell Adhesion/radiation effects

KW - Gene Expression Regulation/radiation effects

KW - Genes, Immediate-Early/genetics

KW - Ion Channel Gating/radiation effects

KW - Mutation/genetics

KW - Organ Specificity/radiation effects

KW - Proto-Oncogene Proteins c-fos/genetics/metabolism

KW - Pyramidal Cells/cytology/metabolism/radiation effects

KW - Rhodopsin/genetics

KW - Animals

KW - Time Factors

KW - Mice

KW - Rats

KW - Light

KW - Action Potentials/radiation effects

KW - Cell Adhesion/radiation effects

KW - Gene Expression Regulation/radiation effects

KW - Genes, Immediate-Early/genetics

KW - Ion Channel Gating/radiation effects

KW - Mutation/genetics

KW - Organ Specificity/radiation effects

KW - Proto-Oncogene Proteins c-fos/genetics/metabolism

KW - Pyramidal Cells/cytology/metabolism/radiation effects

KW - Rhodopsin/genetics

M3 - SCORING: Journal article

VL - 4

SP - 8185

JO - PLOS ONE

JF - PLOS ONE

SN - 1932-6203

IS - 12

M1 - 12

ER -