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  1. 2021

  2. Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation

    Niyonzima, N., Rahman, J., Kunz, N., West, E. E., Freiwald, T., Desai, J. V., Merle, N. S., Gidon, A., Sporsheim, B., Lionakis, M. S., Evensen, K., Lindberg, B., Skagen, K., Skjelland, M., Singh, P., Haug, M., Ruseva, M. M., Kolev, M., Bibby, J., Marshall, O., O’Brien, B., Deeks, N., Afzali, B., Clark, R. J., Woodruff, T. M., Pryor, M., Yang, Z-H., Remaley, A. T., Mollnes, T. E., Hewitt, S. M., Yan, B., Kazemian, M., Kiss, M. G., Binder, C. J., Halvorsen, B., Espevik, T. & Kemper, C., 24.12.2021, In: SCI IMMUNOL. 6, 66, p. eabf2489 eabf2489.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Lack of Evidence for an Association between Previous HEV Genotype-3 Exposure and Glomerulonephritis in General

    Pischke, S., Tamanaei, S., Mader, M., Wiesch, J. S. Z., Petersen-Benz, C., Haddad, M., Addo, M., Schmidt, T., Huber, T. B., Krebs, C. F., Steinmetz, O. M., Turner, J. E., Hoxha, E. & Horvatits, T., 23.12.2021, In: PATHOGENS. 11, 1, 18.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Molecular Mapping of Urinary Complement Peptides in Kidney Diseases

    Wendt, R., Siwy, J., He, T., Latosinska, A., Wiech, T., Zipfel, P. F., Tserga, A., Vlahou, A., Rupprecht, H., Catanese, L., Mischak, H. & Beige, J., 13.12.2021, In: PROTEOMES. 9, 4, 49.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. BET Proteins Regulate Expression of Osr1 in Early Kidney Development

    Schreiber, J., Liaukouskaya, N., Fuhrmann, L., Hauser, A-T., Jung, M., Huber, T. B. & Wanner, N., 10.12.2021, In: BIOMEDICINES. 9, 12, 1878.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. IL-17 receptor c signaling controls CD4+TH17 immune responses and tissue injury in immune-mediated kidney diseases

    Schmidt, T., Luebbe, J., Kilian, C., Riedel, J. H., Hiekmann, S., Asada, N., Ginsberg, P., Robben, L., Song, N., Kaffke, A., Peters, A., Borchers, A., Flavell, R. A., Gagliani, N., Pelzcar, P., Huber, S., Huber, T. B., Turner, J. E., Paust, H. J., Krebs, C. F. & Panzer, U., 12.2021, In: J AM SOC NEPHROL. 32, 12, p. 3081-3098 18 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Increased rejection rates in kidney transplantations during the COVID-19 pandemic

    Schmidt-Lauber, C., Spoden, M., Huber, T. B., Günster, C. & Grahammer, F., 12.2021, In: TRANSPL INT. 34, 12, p. 2899-2902 4 p.

    Research output: SCORING: Contribution to journal › Letter › Research › peer-review

  8. It does not have to be either or! Assessing competence in medicine should be a continuum between an analytic and a holistic approach

    Rotthoff, T., Kadmon, M. & Harendza, S., 12.2021, In: ADV HEALTH SCI EDUC. 26, 5, p. 1659-1673 15 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  9. Towards Explainable End-to-End Prostate Cancer Relapse Prediction from H&E Images Combining Self-Attention Multiple Instance Learning with a Recurrent Neural Network

    Dietrich, E., Fuhlert, P., Ernst, A., Sauter, G., Lennartz, E. M. H., Stiehl, S., Zimmermann, M. & Bonn, S., 26.11.2021, Machine Learning for Health (ML4H) 2021: Proceedings of Machine Learning Research LEAVE UNSET:1–16, 2021. Cornell University, Vol. 158. p. 38-53 16 p.

    Research output: SCORING: Contribution to book/anthology › Conference contribution - Poster › Research

  10. Factor H-related protein 1 (FHR-1) is associated with atherosclerotic cardiovascular disease

    Irmscher, S., Zipfel, S. L. H., Halder, L. D., Ivanov, L., Gonzalez-Delgado, A., Waldeyer, C., Seiffert, M., Brunner, F. J., von der Heide, M., Löschmann, I., Wulf, S., Czamara, D., Papac-Milicevic, N., Strauß, O., Lorkowski, S., Reichenspurner, H., Holers, M. V., Banda, N. K., Zeller, T., Binder, E. B., Binder, C. J., Wiech, T., Zipfel, P. F. & Skerka, C., 18.11.2021, In: SCI REP-UK. 11, 1, 22511.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Role of mTOR Signaling for Tubular Function and Disease

    Grahammer, F., Huber, T. B. & Artunc, F., 01.11.2021, In: PHYSIOLOGY. 36, 6, p. 350-358 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  12. An international cohort study spanning five decades assessed outcomes of nephropathic cystinosis

    Emma, F., Hoff, W. V., Hohenfellner, K., Topaloglu, R., Greco, M., Ariceta, G., Bettini, C., Bockenhauer, D., Veys, K., Pape, L., Hulton, S., Collin, S., Ozaltin, F., Servais, A., Deschênes, G., Novo, R., Bertholet-Thomas, A., Oh, J., Cornelissen, E., Janssen, M., Haffner, D., Ravà, L., Antignac, C., Devuyst, O., Niaudet, P. & Levtchenko, E., 11.2021, In: KIDNEY INT. 100, 5, p. 1112-1123 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. COVID-19 effects on the kidney

    Amann, K., Boor, P., Wiech, T., Singh, J., Vonbrunn, E., Knöll, A., Hermann, M., Büttner-Herold, M., Daniel, C. & Hartmann, A., 11.2021, In: PATHOLOGE. 42, Suppl 1, p. 76-80 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  14. Development and design of the Hantavirus registry - HantaReg - for epidemiological studies, outbreaks and clinical studies on hantavirus disease

    Koehler, F. C., Blomberg, L., Brehm, T. T., Büttner, S., Cornely, O. A., Degen, O., Di Cristanziano, V., Dolff, S., Eberwein, L., Hoxha, E., Hoyer-Allo, K. J. R., Rudolf, S., Späth, M. R., Wanken, M., Müller, R-U. & Burst, V., 11.2021, In: CLIN KIDNEY J. 14, 11, p. 2365-2370 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis

    Müller-Deile, J., Sopel, N., Ohs, A., Rose, V., Gröner, M., Wrede, C., Hegermann, J., Daniel, C., Amann, K., Zahner, G. & Schiffer, M., 11.2021, In: J AM SOC NEPHROL. 32, 11, p. 2777-2794 18 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Hemoconcentration and predictors in Shiga toxin-producing E. coli-hemolytic uremic syndrome (STEC-HUS)

    Loos, S., Oh, J., Loo, L. V. D., Kemper, M. J., Blohm, M. & Schild, R., 11.2021, In: PEDIATR NEPHROL. 36, 11, p. 3777-3783 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. mTOR-Activating Mutations in RRAGD Are Causative for Kidney Tubulopathy and Cardiomyopathy

    Schlingmann, K. P., Jouret, F., Shen, K., Nigam, A., Arjona, F. J., Dafinger, C., Houillier, P., Jones, D. P., Kleinerüschkamp, F., Oh, J., Godefroid, N., Eltan, M., Güran, T., Burtey, S., Parotte, M-C., König, J., Braun, A., Bos, C., Ibars Serra, M., Rehmann, H., Zwartkruis, F. J. T., Renkema, K. Y., Klingel, K., Schulze-Bahr, E., Schermer, B., Bergmann, C., Altmüller, J., Thiele, H., Beck, B. B., Dahan, K., Sabatini, D., Liebau, M. C., Vargas-Poussou, R., Knoers, N. V. A. M., Konrad, M. & de Baaij, J. H. F., 11.2021, In: J AM SOC NEPHROL. 32, 11, p. 2885-2899 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Multiorgan tropism of SARS-CoV-2 lineage B.1.1.7

    Ondruschka, B., Heinrich, F., Lindenmeyer, M., Edler, C., Möbius, D., Czogalla, J., Heinemann, A., Braun, F., Aepfelbacher, M., Lütgehetmann, M. & Huber, T. B., 11.2021, In: INT J LEGAL MED. 135, 6, p. 2347-2349 3 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Neuronal TNFα, Not α-Syn, Underlies PDD-Like Disease Progression in IFNβ-KO Mice

    Villanueva, E. B., Tresse, E., Liu, Y., Duarte, J. N., Jimenez-Duran, G., Ejlerskov, P., Kretz, O., Loreth, D., Goldmann, T., Prinz, M. & Issazadeh-Navikas, S., 11.2021, In: ANN NEUROL. 90, 5, p. 789-807 19 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Renal diseases and the role of complement: Linking complement to immune effector pathways and therapeutics

    Freiwald, T. & Afzali, B., 11.2021, In: ADV IMMUNOL. 152, p. 1-81 81 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  21. Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice

    Berghoff, S. A., Spieth, L., Sun, T., Hosang, L., Depp, C., Sasmita, A. O., Vasileva, M. H., Scholz, P., Zhao, Y., Krueger-Burg, D., Wichert, S., Brown, E. R., Michail, K., Nave, K-A., Bonn, S., Odoardi, F., Rossner, M., Ischebeck, T., Edgar, J. M. & Saher, G., 26.10.2021, In: CELL REP. 37, 4, 109889.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression

    Schneider, E., Winzer, R., Rissiek, A., Ricklefs, I., Meyer-Schwesinger, C., Ricklefs, F. L., Bauche, A., Behrends, J., Reimer, R., Brenna, S., Wasielewski, H., Lauten, M., Rissiek, B., Puig, B., Cortesi, F., Magnus, T., Fliegert, R., Müller, C. E., Gagliani, N. & Tolosa, E., 08.10.2021, In: NAT COMMUN. 12, 1, p. 5911

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Atypical Hemolytic and Uremic Syndrome Triggered by Infection With SARS-CoV2

    Kaufeld, J., Reinhardt, M., Schröder, C., Bräsen, J. H., Wiech, T., Brylka, P., Khaled, A., Bergmann, C., Haller, H., Gäckler, A. & Schmidt, B. M. W., 10.2021, In: KIDNEY INT REP. 6, 10, p. 2709-2712 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. CD99 and polymeric immunoglobulin receptor peptides deregulation in critical COVID-19: A potential link to molecular pathophysiology?

    Siwy, J., Wendt, R., Albalat, A., He, T., Mischak, H., Mullen, W., Latosinska, A., Lübbert, C., Kalbitz, S., Mebazaa, A., Peters, B., Stegmayr, B., Spasovski, G., Wiech, T., Staessen, J. A., Wolf, J. & Beige, J., 10.2021, In: PROTEOMICS. 21, 20, e2100133.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Clearly imaging and quantifying the kidney in 3D

    Puelles, V. G., Combes, A. N. & Bertram, J. F., 10.2021, In: KIDNEY INT. 100, 4, p. 780-786 7 p.

    Research output: SCORING: Contribution to journal › Short publication › Research › peer-review

  26. Commentary on "Pediatric Idiopathic Steroid-sensitive Nephrotic Syndrome Diagnosis and Therapy - Short version of the updated German Best Practice Guideline (S2e)"

    Ehren, R., Benz, M. R., Brinkkötter, P. T., Dötsch, J., Eberl, W. R., Gellermann, J., Hoyer, P. F., Jordans, I., Kamrath, C., Kemper, M. J., Latta, K., Müller, D., Oh, J., Tönshoff, B., Weber, S., Weber, L. T. & German Society of Pediatric Nephrology, 10.2021, In: PEDIATR NEPHROL. 36, 10, p. 2961-2966 6 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  27. Pediatric idiopathic steroid-sensitive nephrotic syndrome diagnosis and therapy -short version of the updated German best practice guideline (S2e) - AWMF register no. 166-001, 6/2020

    Ehren, R., Benz, M. R., Brinkkötter, P. T., Dötsch, J., Eberl, W. R., Gellermann, J., Hoyer, P. F., Jordans, I., Kamrath, C., Kemper, M. J., Latta, K., Müller, D., Oh, J., Tönshoff, B., Weber, S., Weber, L. T. & German Society of Pediatric Nephrology, 10.2021, In: PEDIATR NEPHROL. 36, 10, p. 2971-2985 15 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  28. Specific disruption of calcineurin-signaling in the distal convoluted tubule impacts the transcriptome and proteome, and causes hypomagnesemia and metabolic acidosis

    Banki, E., Fisi, V., Moser, S., Wengi, A., Carrel, M., Loffing-Cueni, D., Penton, D., Kratschmar, D. V., Rizzo, L., Lienkamp, S., Odermatt, A., Rinschen, M. M. & Loffing, J., 10.2021, In: KIDNEY INT. 100, 4, p. 850-869 20 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Bias-invariant RNA-sequencing metadata annotation

    Wartmann, H., Heins, S., Kloiber, K. & Bonn, S., 22.09.2021, In: GIGASCIENCE. 10, 9, p. giab064

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. The Atypical Cyclin-Dependent Kinase 5 (Cdk5) Guards Podocytes from Apoptosis in Glomerular Disease While Being Dispensable for Podocyte Development

    Mangold, N., Pippin, J., Unnersjö-Jess, D., Koehler, S., Shankland, S. J., Brähler, S., Schermer, B., Benzing, T., Brinkkoetter, P. T. & Hagmann, H., 18.09.2021, In: CELLS-BASEL. 10, 9, 2464.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. KIR3DS1 directs NK cell-mediated protection against human adenovirus infections

    Jung, J. M., Ching, W., Baumdick, M. E., Hofmann-Sieber, H., Bosse, J. B., Koyro, T., Möller, K. J., Wegner, L., Niehrs, A., Russu, K., Ohms, M., Zhang, W., Ehrhardt, A., Duisters, K., Spierings, E., Hölzemer, A., Körner, C., Jansen, S. A., Peine, S., Königs, I., Lütgehetmann, M., Perez, D., Reinshagen, K., Lindemans, C. A., Altfeld, M., Belderbos, M., Dobner, T. & Bunders, M. J., 17.09.2021, In: SCI IMMUNOL. 6, 63, eabe2942.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Immune Thrombocytopenic Purpura after vaccination with COVID-19 Vaccine (ChAdOx1 nCov-19)

    Paulsen, F-O., Schaefers, C., Langer, F., Frenzel, C., Wenzel, U., Hengel, F. E., Bokemeyer, C. & Seidel, C., 16.09.2021, In: BLOOD. 138, 11, p. 996-999 4 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  33. The Intertwining of Autophagy and the Ubiquitin Proteasome System in Podocyte (Patho)Physiology

    Heintz, L. & Meyer-Schwesinger, C., 15.09.2021, In: CELL PHYSIOL BIOCHEM. 55, S4, p. 68-95 28 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  34. Podocyte endowment and the impact of adult body size on kidney health

    Cullen-McEwen, L. A., van der Wolde, J., Haruhara, K., Tribolet, L., Dowling, J. P., Bertram, M. G., de Matteo, R., Haas, F., Czogalla, J., Okabayashi, Y., Armitage, J. A., Black, M. J., Hoy, W. E., Puelles, V. G. & Bertram, J. F., 01.09.2021, In: AM J PHYSIOL-RENAL. 321, 3, p. F322-F334

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Cardiac perforation due to delayed migration of a chronic dialysis catheter: a case report

    Jahnke, C., Hoxha, E., Söffker, G. & Seiffert, M., 09.2021, In: EUR HEART J-CASE REP. 5, 9, p. ytab332

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. Post-transplant nephrotic syndrome resulting from NELL1-positive membranous nephropathy

    Münch, J., Krüger, B. M., Weimann, A., Wiech, T., Reinhard, L., Hoxha, E., Pfister, F. & Halbritter, J., 09.2021, In: AM J TRANSPLANT. 21, 9, p. 3175-3179 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Tripartite Separation of Glomerular Cell-Types and Proteomes From Reporter-Free Mice

    Hatje, F., Wedekind, U., Sachs, W., Loreth, D., Reichelt, J., Demir, F., Kosub, C., Heintz, L., Tomas, N., Huber, T., Skuza, S., Sachs, M., Zielinski, S., Rinschen, M. & Meyer-Schwesinger, C., 09.2021, In: J AM SOC NEPHROL. 32, 9, p. 2175-2193 19 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Characterization of THSD7A-antibodies not binding to glomerular THSD7A in a patient with diabetes mellitus but no membranous nephropathy

    Reinhard, L., Thomas, C., Machalitza, M., Lattwein, E., Weiss, L. S., Vitu, J., Wiech, T., Stahl, R. A. K. & Hoxha, E., 10.08.2021, In: SCI REP-UK. 11, 1, 16188.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Maintaining proteostasis under mechanical stress

    Höhfeld, J., Benzing, T., Bloch, W., Fürst, D. O., Gehlert, S., Hesse, M., Hoffmann, B., Hoppe, T., Huesgen, P. F., Köhn, M., Kolanus, W., Merkel, R., Niessen, C. M., Pokrzywa, W., Rinschen, M. M., Wachten, D. & Warscheid, B., 04.08.2021, In: EMBO REP. 22, 8, e52507.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  40. Across scales: novel insights into kidney health and disease by structural biology

    Tomas, N. M., Mortensen, S. A., Wilmanns, M. & Huber, T. B., 08.2021, In: KIDNEY INT. 100, 2, p. 281-288 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  41. Complement catalyzing glomerular diseases

    Zipfel, P. F., Wiech, T., Gröne, H-J. & Skerka, C., 08.2021, In: CELL TISSUE RES. 385, 2, p. 355-370 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  42. Convalescent plasma treatment for early post-kidney-transplant acquired COVID-19

    Kluger, M. A., Czogalla, J., Schmidt-Lauber, C., Peine, S., Schmiedel, S., Bangert, K., Kluge, S., Huber, S., Puelles, V. G., Fischer, L., Huber, T. B. & Grahammer, F., 08.2021, In: TRANSPL INFECT DIS. 23, 4, p. e13685 e13685.

    Research output: SCORING: Contribution to journal › Letter › Research › peer-review

  43. Immune mechanisms in arterial hypertension. Recent advances

    Wenzel, U. O., Ehmke, H. & Bode, M., 08.2021, In: CELL TISSUE RES. 385, 2, p. 393-404 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  44. Immune-mediated entities of (primary) focal segmental glomerulosclerosis

    Braun, F., Homeyer, I., Alachkar, N. & Huber, T. B., 08.2021, In: CELL TISSUE RES. 385, 2, p. 423-434 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  45. Immune-mediated glomerular diseases: new basic concepts and clinical implications

    Panzer, U. & Huber, T. B., 08.2021, In: CELL TISSUE RES. 385, 2, p. 277-279 3 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  46. Kidney organoid systems for studies of immune-mediated kidney diseases: challenges and opportunities

    Stein, M. C., Braun, F., Krebs, C. F. & Bunders, M. J., 08.2021, In: CELL TISSUE RES. 385, 2, p. 457-473 17 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  47. Lysosome function in glomerular health and disease

    Meyer-Schwesinger, C., 08.2021, In: CELL TISSUE RES. 385, 2, p. 371-392 22 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  48. Nanobodies: new avenue to treat kidney disease

    Wanner, N., Eden, T., Liaukouskaya, N. & Koch-Nolte, F., 08.2021, In: CELL TISSUE RES. 385, 2, p. 445-456 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  49. Neutralization of IL-6 inhibits formation of autoreactive TH17 cells but does not prevent loss of renal function in experimental autoimmune glomerulonephritis

    Brede, K-M., Schmid, J., Steinmetz, O. M., Panzer, U., Klinge, S. & Mittrücker, H-W., 08.2021, In: IMMUNOL LETT. 236, p. 51-60 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. Parietal epithelial cell dysfunction in crescentic glomerulonephritis

    Wong, M. N., Tharaux, P-L., Grahammer, F. & Puelles, V. G., 08.2021, In: CELL TISSUE RES. 385, 2, p. 345-354 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  51. Perspectives in membranous nephropathy

    Tomas, N. M., Huber, T. B. & Hoxha, E., 08.2021, In: CELL TISSUE RES. 385, 2, p. 405-422 18 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

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