Across scales: novel insights into kidney health and disease by structural biology
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Abstract
Over the past decades, structural biology methods such as X-ray crystallography and cryo-electron microscopy have been increasingly used to study protein functions, molecular interactions, physiological processes, and disease mechanisms. This review outlines a selection of structural biology methods, highlights recent examples of how structural analyses have contributed to a more profound understanding of the machinery of life, and gives a perspective on how these methods can be applied to investigate functions of kidney molecules and pathogenic mechanisms of renal diseases.
Bibliographical data
Original language | English |
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ISSN | 0085-2538 |
DOIs | |
Publication status | Published - 08.2021 |
Comment Deanary
Copyright © 2021 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.
PubMed | 33940110 |
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