Research ExplorerPublicationsNeuroCOVID: Insights into Neuroinvasion and Pathophysiology

NeuroCOVID: Insights into Neuroinvasion and Pathophysiology

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NeuroCOVID: Insights into Neuroinvasion and Pathophysiology. / Matschke, Jakob; Krasemann, Susanne; Altmeppen, Hermann; Shafiq, Mohsin; Glatzel, Markus.

In: Clinical and Translational Neuroscience, Vol. 6, No. 2, 10, 04.2022.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Matschke, J, Krasemann, S, Altmeppen, H, Shafiq, M & Glatzel, M 2022, 'NeuroCOVID: Insights into Neuroinvasion and Pathophysiology', Clinical and Translational Neuroscience, vol. 6, no. 2, 10. https://doi.org/10.3390/ctn6020010

APA

Matschke, J., Krasemann, S., Altmeppen, H., Shafiq, M., & Glatzel, M. (2022). NeuroCOVID: Insights into Neuroinvasion and Pathophysiology. Clinical and Translational Neuroscience, 6(2), [10]. https://doi.org/10.3390/ctn6020010

Vancouver

Matschke J, Krasemann S, Altmeppen H, Shafiq M, Glatzel M. NeuroCOVID: Insights into Neuroinvasion and Pathophysiology. Clinical and Translational Neuroscience. 2022 Apr;6(2). 10. https://doi.org/10.3390/ctn6020010

Bibtex

@article{b3a462f7282843798a5c2e661b1db872,
title = "NeuroCOVID: Insights into Neuroinvasion and Pathophysiology",
abstract = "Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may lead to acute and chronic neurological symptoms (NeuroCOVID-19). SARS-CoV-2 may spread from the respiratory tract to the central nervous system as the central nervous system (CNS) of certain patients dying from COVID-19 shows virus-related neuropathological changes. Moreover, a syndrome found in many patients having passed a SARS-CoV-2 infection, which is termed long COVID and characterized by lasting fatigue and other diverse clinical features, may well have some of its pathological correlates inside the CNS. Although knowledge on the routes of SARS-CoV-2 neuroinvasion and the pathophysiology of NeuroCOVID have increased, the molecular mechanisms are not yet fully understood. This includes the key question: to understand if observed CNS damage is a direct cause of viral damage or indirectly mediated by an overshooting neuroimmune response.",
author = "Jakob Matschke and Susanne Krasemann and Hermann Altmeppen and Mohsin Shafiq and Markus Glatzel",
year = "2022",
month = apr,
doi = "10.3390/ctn6020010",
language = "English",
volume = "6",
journal = "Clinical and Translational Neuroscience",
issn = "2514-183X",
number = "2",

}

RIS

TY - JOUR

T1 - NeuroCOVID: Insights into Neuroinvasion and Pathophysiology

AU - Matschke, Jakob

AU - Krasemann, Susanne

AU - Altmeppen, Hermann

AU - Shafiq, Mohsin

AU - Glatzel, Markus

PY - 2022/4

Y1 - 2022/4

N2 - Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may lead to acute and chronic neurological symptoms (NeuroCOVID-19). SARS-CoV-2 may spread from the respiratory tract to the central nervous system as the central nervous system (CNS) of certain patients dying from COVID-19 shows virus-related neuropathological changes. Moreover, a syndrome found in many patients having passed a SARS-CoV-2 infection, which is termed long COVID and characterized by lasting fatigue and other diverse clinical features, may well have some of its pathological correlates inside the CNS. Although knowledge on the routes of SARS-CoV-2 neuroinvasion and the pathophysiology of NeuroCOVID have increased, the molecular mechanisms are not yet fully understood. This includes the key question: to understand if observed CNS damage is a direct cause of viral damage or indirectly mediated by an overshooting neuroimmune response.

AB - Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may lead to acute and chronic neurological symptoms (NeuroCOVID-19). SARS-CoV-2 may spread from the respiratory tract to the central nervous system as the central nervous system (CNS) of certain patients dying from COVID-19 shows virus-related neuropathological changes. Moreover, a syndrome found in many patients having passed a SARS-CoV-2 infection, which is termed long COVID and characterized by lasting fatigue and other diverse clinical features, may well have some of its pathological correlates inside the CNS. Although knowledge on the routes of SARS-CoV-2 neuroinvasion and the pathophysiology of NeuroCOVID have increased, the molecular mechanisms are not yet fully understood. This includes the key question: to understand if observed CNS damage is a direct cause of viral damage or indirectly mediated by an overshooting neuroimmune response.

UR - https://www.mdpi.com/2514-183X/6/2/10

U2 - 10.3390/ctn6020010

DO - 10.3390/ctn6020010

M3 - SCORING: Review article

VL - 6

JO - Clinical and Translational Neuroscience

JF - Clinical and Translational Neuroscience

SN - 2514-183X

IS - 2

M1 - 10

ER -