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mecA is not involved in the sigmaB-dependent switch of the expression phenotype of methicillin resistance in Staphylococcus epidermidis

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mecA is not involved in the sigmaB-dependent switch of the expression phenotype of methicillin resistance in Staphylococcus epidermidis. / Knobloch, Johannes K-M; Jäger, Sebastian; Huck, Jörn; Horstkotte, Matthias A; Mack, Dietrich.

In: ANTIMICROB AGENTS CH, Vol. 49, No. 3, 03.2005, p. 1216-9.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Knobloch, JK-M, Jäger, S, Huck, J, Horstkotte, MA & Mack, D 2005, 'mecA is not involved in the sigmaB-dependent switch of the expression phenotype of methicillin resistance in Staphylococcus epidermidis', ANTIMICROB AGENTS CH, vol. 49, no. 3, pp. 1216-9. https://doi.org/10.1128/AAC.49.3.1216-1219.2005

APA

Knobloch, J. K-M., Jäger, S., Huck, J., Horstkotte, M. A., & Mack, D. (2005). mecA is not involved in the sigmaB-dependent switch of the expression phenotype of methicillin resistance in Staphylococcus epidermidis. ANTIMICROB AGENTS CH, 49(3), 1216-9. https://doi.org/10.1128/AAC.49.3.1216-1219.2005

Vancouver

Knobloch JK-M, Jäger S, Huck J, Horstkotte MA, Mack D. mecA is not involved in the sigmaB-dependent switch of the expression phenotype of methicillin resistance in Staphylococcus epidermidis. ANTIMICROB AGENTS CH. 2005 Mar;49(3):1216-9. https://doi.org/10.1128/AAC.49.3.1216-1219.2005

Bibtex

@article{fe9c203337ed49f08ea21a48e618d288,
title = "mecA is not involved in the sigmaB-dependent switch of the expression phenotype of methicillin resistance in Staphylococcus epidermidis",
abstract = "A lack of sigma(B) activity reduces methicillin resistance in heterogeneous Staphylococcus epidermidis 1057, whereas inactivation of the anti-sigma factor RsbW switched the phenotype to homogeneous expression of resistance. Oxacillin induction of mecA transcription is reduced in a sigma(B)-negative strain. However, mecA is not involved in the switch of expression phenotype.",
keywords = "Bacterial Proteins/genetics, Methicillin Resistance, Oxacillin/pharmacology, Phenotype, Reverse Transcriptase Polymerase Chain Reaction, Sigma Factor/physiology, Staphylococcus epidermidis/drug effects, Transcription, Genetic",
author = "Knobloch, {Johannes K-M} and Sebastian J{\"a}ger and J{\"o}rn Huck and Horstkotte, {Matthias A} and Dietrich Mack",
year = "2005",
month = mar,
doi = "10.1128/AAC.49.3.1216-1219.2005",
language = "English",
volume = "49",
pages = "1216--9",
journal = "ANTIMICROB AGENTS CH",
issn = "0066-4804",
publisher = "American Society for Microbiology",
number = "3",

}

RIS

TY - JOUR

T1 - mecA is not involved in the sigmaB-dependent switch of the expression phenotype of methicillin resistance in Staphylococcus epidermidis

AU - Knobloch, Johannes K-M

AU - Jäger, Sebastian

AU - Huck, Jörn

AU - Horstkotte, Matthias A

AU - Mack, Dietrich

PY - 2005/3

Y1 - 2005/3

N2 - A lack of sigma(B) activity reduces methicillin resistance in heterogeneous Staphylococcus epidermidis 1057, whereas inactivation of the anti-sigma factor RsbW switched the phenotype to homogeneous expression of resistance. Oxacillin induction of mecA transcription is reduced in a sigma(B)-negative strain. However, mecA is not involved in the switch of expression phenotype.

AB - A lack of sigma(B) activity reduces methicillin resistance in heterogeneous Staphylococcus epidermidis 1057, whereas inactivation of the anti-sigma factor RsbW switched the phenotype to homogeneous expression of resistance. Oxacillin induction of mecA transcription is reduced in a sigma(B)-negative strain. However, mecA is not involved in the switch of expression phenotype.

KW - Bacterial Proteins/genetics

KW - Methicillin Resistance

KW - Oxacillin/pharmacology

KW - Phenotype

KW - Reverse Transcriptase Polymerase Chain Reaction

KW - Sigma Factor/physiology

KW - Staphylococcus epidermidis/drug effects

KW - Transcription, Genetic

U2 - 10.1128/AAC.49.3.1216-1219.2005

DO - 10.1128/AAC.49.3.1216-1219.2005

M3 - SCORING: Journal article

C2 - 15728932

VL - 49

SP - 1216

EP - 1219

JO - ANTIMICROB AGENTS CH

JF - ANTIMICROB AGENTS CH

SN - 0066-4804

IS - 3

ER -