mecA is not involved in the sigmaB-dependent switch of the expression phenotype of methicillin resistance in Staphylococcus epidermidis
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Abstract
A lack of sigma(B) activity reduces methicillin resistance in heterogeneous Staphylococcus epidermidis 1057, whereas inactivation of the anti-sigma factor RsbW switched the phenotype to homogeneous expression of resistance. Oxacillin induction of mecA transcription is reduced in a sigma(B)-negative strain. However, mecA is not involved in the switch of expression phenotype.
Bibliographical data
Original language | English |
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ISSN | 0066-4804 |
DOIs | |
Publication status | Published - 03.2005 |
PubMed | 15728932 |
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