Effect of heat-shock protein-90 (HSP90) inhibition on human hepatocytes and on liver regeneration in experimental models.
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Abstract
Targeting heat shock protein 90 (HSP90) has gained great interest for cancer therapy. However, in view of novel multimodality therapy approaches for treating hepatic metastases, concerns have raised regarding the impact of targeted therapies on liver regeneration and repair. In this study, we investigated the impact of HSP90 inhibition on liver regeneration in murine models.
Bibliographical data
| Original language | German |
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| Article number | 5 |
| ISSN | 0039-6060 |
| Publication status | Published - 2010 |
| pubmed | 20015528 |
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