Effect of heat-shock protein-90 (HSP90) inhibition on human hepatocytes and on liver regeneration in experimental models.
Standard
Effect of heat-shock protein-90 (HSP90) inhibition on human hepatocytes and on liver regeneration in experimental models. / Hackl, Christina; Mori, Akira; Moser, Christian; Lang, Sven A; Dayoub, Rania; Weiss, Thomas S; Schlitt, Hans J; Geissler, Edward K; Hellerbrand, Claus; Stöltzing, Oliver.
In: SURGERY, Vol. 147, No. 5, 5, 2010, p. 704-712.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Effect of heat-shock protein-90 (HSP90) inhibition on human hepatocytes and on liver regeneration in experimental models.
AU - Hackl, Christina
AU - Mori, Akira
AU - Moser, Christian
AU - Lang, Sven A
AU - Dayoub, Rania
AU - Weiss, Thomas S
AU - Schlitt, Hans J
AU - Geissler, Edward K
AU - Hellerbrand, Claus
AU - Stöltzing, Oliver
PY - 2010
Y1 - 2010
N2 - Targeting heat shock protein 90 (HSP90) has gained great interest for cancer therapy. However, in view of novel multimodality therapy approaches for treating hepatic metastases, concerns have raised regarding the impact of targeted therapies on liver regeneration and repair. In this study, we investigated the impact of HSP90 inhibition on liver regeneration in murine models.
AB - Targeting heat shock protein 90 (HSP90) has gained great interest for cancer therapy. However, in view of novel multimodality therapy approaches for treating hepatic metastases, concerns have raised regarding the impact of targeted therapies on liver regeneration and repair. In this study, we investigated the impact of HSP90 inhibition on liver regeneration in murine models.
M3 - SCORING: Zeitschriftenaufsatz
VL - 147
SP - 704
EP - 712
JO - SURGERY
JF - SURGERY
SN - 0039-6060
IS - 5
M1 - 5
ER -