Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice.

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Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice. / Bertrand, J; Nitschke, Y; Fuerst, Martin; Hermann, S; Schäfers, M; Sherwood, J; Nalesso, G; Rüther, Wolfgang; Rutsch, F; Dell'Accio, F; Pap, T.

In: ANN RHEUM DIS, Vol. 71, No. 7, 7, 2012, p. 1249-1253.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Bertrand, J, Nitschke, Y, Fuerst, M, Hermann, S, Schäfers, M, Sherwood, J, Nalesso, G, Rüther, W, Rutsch, F, Dell'Accio, F & Pap, T 2012, 'Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice.', ANN RHEUM DIS, vol. 71, no. 7, 7, pp. 1249-1253. <http://www.ncbi.nlm.nih.gov/pubmed/22510396?dopt=Citation>

APA

Bertrand, J., Nitschke, Y., Fuerst, M., Hermann, S., Schäfers, M., Sherwood, J., Nalesso, G., Rüther, W., Rutsch, F., Dell'Accio, F., & Pap, T. (2012). Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice. ANN RHEUM DIS, 71(7), 1249-1253. [7]. http://www.ncbi.nlm.nih.gov/pubmed/22510396?dopt=Citation

Vancouver

Bibtex

@article{7ee30a0a75a14f6a990e89d5b8b3aa5e,
title = "Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice.",
abstract = "To analyse the function of nucleotide pyrophosphatase phosphodiesterase (NPP1), a member of the pyrophosphate pathway, in osteoarthritis (OA).",
keywords = "Animals, Humans, Severity of Illness Index, Mice, Mice, Knockout, Signal Transduction, Biological Markers/metabolism, Gene Expression Regulation, Enzymologic, RNA, Messenger/metabolism, Alkaline Phosphatase/genetics/metabolism, Arthritis, Experimental/*metabolism/pathology, Calcinosis/*metabolism/pathology, Cartilage, Articular/*metabolism/pathology, Collagen Type X/metabolism, Osteoarthritis, Knee/*metabolism/pathology/surgery, Phosphate Transport Proteins/genetics/metabolism, Phosphoric Diester Hydrolases/genetics/*metabolism, Pyrophosphatases/genetics/*metabolism, Stifle/metabolism/pathology, Animals, Humans, Severity of Illness Index, Mice, Mice, Knockout, Signal Transduction, Biological Markers/metabolism, Gene Expression Regulation, Enzymologic, RNA, Messenger/metabolism, Alkaline Phosphatase/genetics/metabolism, Arthritis, Experimental/*metabolism/pathology, Calcinosis/*metabolism/pathology, Cartilage, Articular/*metabolism/pathology, Collagen Type X/metabolism, Osteoarthritis, Knee/*metabolism/pathology/surgery, Phosphate Transport Proteins/genetics/metabolism, Phosphoric Diester Hydrolases/genetics/*metabolism, Pyrophosphatases/genetics/*metabolism, Stifle/metabolism/pathology",
author = "J Bertrand and Y Nitschke and Martin Fuerst and S Hermann and M Sch{\"a}fers and J Sherwood and G Nalesso and Wolfgang R{\"u}ther and F Rutsch and F Dell'Accio and T Pap",
year = "2012",
language = "English",
volume = "71",
pages = "1249--1253",
journal = "ANN RHEUM DIS",
issn = "0003-4967",
publisher = "BMJ PUBLISHING GROUP",
number = "7",

}

RIS

TY - JOUR

T1 - Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice.

AU - Bertrand, J

AU - Nitschke, Y

AU - Fuerst, Martin

AU - Hermann, S

AU - Schäfers, M

AU - Sherwood, J

AU - Nalesso, G

AU - Rüther, Wolfgang

AU - Rutsch, F

AU - Dell'Accio, F

AU - Pap, T

PY - 2012

Y1 - 2012

N2 - To analyse the function of nucleotide pyrophosphatase phosphodiesterase (NPP1), a member of the pyrophosphate pathway, in osteoarthritis (OA).

AB - To analyse the function of nucleotide pyrophosphatase phosphodiesterase (NPP1), a member of the pyrophosphate pathway, in osteoarthritis (OA).

KW - Animals

KW - Humans

KW - Severity of Illness Index

KW - Mice

KW - Mice, Knockout

KW - Signal Transduction

KW - Biological Markers/metabolism

KW - Gene Expression Regulation, Enzymologic

KW - RNA, Messenger/metabolism

KW - Alkaline Phosphatase/genetics/metabolism

KW - Arthritis, Experimental/metabolism/pathology

KW - Calcinosis/metabolism/pathology

KW - Cartilage, Articular/metabolism/pathology

KW - Collagen Type X/metabolism

KW - Osteoarthritis, Knee/metabolism/pathology/surgery

KW - Phosphate Transport Proteins/genetics/metabolism

KW - Phosphoric Diester Hydrolases/genetics/metabolism

KW - Pyrophosphatases/genetics/metabolism

KW - Stifle/metabolism/pathology

KW - Animals

KW - Humans

KW - Severity of Illness Index

KW - Mice

KW - Mice, Knockout

KW - Signal Transduction

KW - Biological Markers/metabolism

KW - Gene Expression Regulation, Enzymologic

KW - RNA, Messenger/metabolism

KW - Alkaline Phosphatase/genetics/metabolism

KW - Arthritis, Experimental/metabolism/pathology

KW - Calcinosis/metabolism/pathology

KW - Cartilage, Articular/metabolism/pathology

KW - Collagen Type X/metabolism

KW - Osteoarthritis, Knee/metabolism/pathology/surgery

KW - Phosphate Transport Proteins/genetics/metabolism

KW - Phosphoric Diester Hydrolases/genetics/metabolism

KW - Pyrophosphatases/genetics/metabolism

KW - Stifle/metabolism/pathology

M3 - SCORING: Journal article

VL - 71

SP - 1249

EP - 1253

JO - ANN RHEUM DIS

JF - ANN RHEUM DIS

SN - 0003-4967

IS - 7

M1 - 7

ER -