Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice.
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Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice. / Bertrand, J; Nitschke, Y; Fuerst, Martin; Hermann, S; Schäfers, M; Sherwood, J; Nalesso, G; Rüther, Wolfgang; Rutsch, F; Dell'Accio, F; Pap, T.
in: ANN RHEUM DIS, Jahrgang 71, Nr. 7, 7, 2012, S. 1249-1253.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice.
AU - Bertrand, J
AU - Nitschke, Y
AU - Fuerst, Martin
AU - Hermann, S
AU - Schäfers, M
AU - Sherwood, J
AU - Nalesso, G
AU - Rüther, Wolfgang
AU - Rutsch, F
AU - Dell'Accio, F
AU - Pap, T
PY - 2012
Y1 - 2012
N2 - To analyse the function of nucleotide pyrophosphatase phosphodiesterase (NPP1), a member of the pyrophosphate pathway, in osteoarthritis (OA).
AB - To analyse the function of nucleotide pyrophosphatase phosphodiesterase (NPP1), a member of the pyrophosphate pathway, in osteoarthritis (OA).
KW - Animals
KW - Humans
KW - Severity of Illness Index
KW - Mice
KW - Mice, Knockout
KW - Signal Transduction
KW - Biological Markers/metabolism
KW - Gene Expression Regulation, Enzymologic
KW - RNA, Messenger/metabolism
KW - Alkaline Phosphatase/genetics/metabolism
KW - Arthritis, Experimental/metabolism/pathology
KW - Calcinosis/metabolism/pathology
KW - Cartilage, Articular/metabolism/pathology
KW - Collagen Type X/metabolism
KW - Osteoarthritis, Knee/metabolism/pathology/surgery
KW - Phosphate Transport Proteins/genetics/metabolism
KW - Phosphoric Diester Hydrolases/genetics/metabolism
KW - Pyrophosphatases/genetics/metabolism
KW - Stifle/metabolism/pathology
KW - Animals
KW - Humans
KW - Severity of Illness Index
KW - Mice
KW - Mice, Knockout
KW - Signal Transduction
KW - Biological Markers/metabolism
KW - Gene Expression Regulation, Enzymologic
KW - RNA, Messenger/metabolism
KW - Alkaline Phosphatase/genetics/metabolism
KW - Arthritis, Experimental/metabolism/pathology
KW - Calcinosis/metabolism/pathology
KW - Cartilage, Articular/metabolism/pathology
KW - Collagen Type X/metabolism
KW - Osteoarthritis, Knee/metabolism/pathology/surgery
KW - Phosphate Transport Proteins/genetics/metabolism
KW - Phosphoric Diester Hydrolases/genetics/metabolism
KW - Pyrophosphatases/genetics/metabolism
KW - Stifle/metabolism/pathology
M3 - SCORING: Journal article
VL - 71
SP - 1249
EP - 1253
JO - ANN RHEUM DIS
JF - ANN RHEUM DIS
SN - 0003-4967
IS - 7
M1 - 7
ER -