Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice.

  • J Bertrand
  • Y Nitschke
  • Martin Fuerst
  • S Hermann
  • M Schäfers
  • J Sherwood
  • G Nalesso
  • Wolfgang Rüther
  • F Rutsch
  • F Dell'Accio
  • T Pap

Abstract

To analyse the function of nucleotide pyrophosphatase phosphodiesterase (NPP1), a member of the pyrophosphate pathway, in osteoarthritis (OA).

Bibliographical data

Original languageEnglish
Article number7
ISSN0003-4967
Publication statusPublished - 2012
pubmed 22510396