Chlormadinone acetate suppresses prostaglandin biosynthesis in human endometrial explants.
Related Research units
Abstract
To elucidate the mode of action of chlormadinone acetate (CMA) in reducing dysmenorrheic pain by studying the effects of CMA and dexamethasone (DEX) on messenger RNA (mRNA) abundance of cyclo-oxygenase-2 (COX-2), annexin-1 (ANXA1), glucocorticoid receptor (GR), progesterone receptor (PR), and concentrations of prostaglandin F(2?) (PGF(2?)) and leukotrienes B(4) (LTB(4)) and C(4) (LTC(4)) in human endometrial explants.
Bibliographical data
| Original language | English |
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| Article number | 4 |
| ISSN | 0015-0282 |
| Publication status | Published - 2012 |
| pubmed | 22769735 |
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