PortalPublikationenChlormadinone acetate suppresses prostaglandin biosynthesis ...

Chlormadinone acetate suppresses prostaglandin biosynthesis in human endometrial explants.

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  • Aida Hanjalic-Beck
  • Wolfgang R Schäfer
  • Wolfgang Deppert
  • Lara Fischer
  • Antonia Stein
  • Laura Seebacher
  • von Gradowski
  • Akou Seli
  • Johanna Stuckenschneider
  • Hans P Zahradnik

Beteiligte Einrichtungen

Abstract

To elucidate the mode of action of chlormadinone acetate (CMA) in reducing dysmenorrheic pain by studying the effects of CMA and dexamethasone (DEX) on messenger RNA (mRNA) abundance of cyclo-oxygenase-2 (COX-2), annexin-1 (ANXA1), glucocorticoid receptor (GR), progesterone receptor (PR), and concentrations of prostaglandin F(2?) (PGF(2?)) and leukotrienes B(4) (LTB(4)) and C(4) (LTC(4)) in human endometrial explants.

Bibliografische Daten

OriginalspracheEnglisch
Aufsatznummer4
ISSN0015-0282
StatusVeröffentlicht - 2012
pubmed 22769735