Chlormadinone acetate suppresses prostaglandin biosynthesis in human endometrial explants.
Standard
Chlormadinone acetate suppresses prostaglandin biosynthesis in human endometrial explants. / Hanjalic-Beck, Aida; Schäfer, Wolfgang R; Deppert, Wolfgang; Fischer, Lara; Stein, Antonia; Seebacher, Laura; Gradowski, von; Seli, Akou; Stuckenschneider, Johanna; Zahradnik, Hans P.
In: FERTIL STERIL, Vol. 98, No. 4, 4, 2012, p. 1017-1022.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Chlormadinone acetate suppresses prostaglandin biosynthesis in human endometrial explants.
AU - Hanjalic-Beck, Aida
AU - Schäfer, Wolfgang R
AU - Deppert, Wolfgang
AU - Fischer, Lara
AU - Stein, Antonia
AU - Seebacher, Laura
AU - Gradowski, von
AU - Seli, Akou
AU - Stuckenschneider, Johanna
AU - Zahradnik, Hans P
PY - 2012
Y1 - 2012
N2 - To elucidate the mode of action of chlormadinone acetate (CMA) in reducing dysmenorrheic pain by studying the effects of CMA and dexamethasone (DEX) on messenger RNA (mRNA) abundance of cyclo-oxygenase-2 (COX-2), annexin-1 (ANXA1), glucocorticoid receptor (GR), progesterone receptor (PR), and concentrations of prostaglandin F(2?) (PGF(2?)) and leukotrienes B(4) (LTB(4)) and C(4) (LTC(4)) in human endometrial explants.
AB - To elucidate the mode of action of chlormadinone acetate (CMA) in reducing dysmenorrheic pain by studying the effects of CMA and dexamethasone (DEX) on messenger RNA (mRNA) abundance of cyclo-oxygenase-2 (COX-2), annexin-1 (ANXA1), glucocorticoid receptor (GR), progesterone receptor (PR), and concentrations of prostaglandin F(2?) (PGF(2?)) and leukotrienes B(4) (LTB(4)) and C(4) (LTC(4)) in human endometrial explants.
KW - Adult
KW - Humans
KW - Female
KW - Adolescent
KW - Young Adult
KW - Organ Culture Techniques
KW - RNA, Messenger/metabolism
KW - Dinoprost/metabolism
KW - Glucocorticoids/pharmacology
KW - Receptors, Glucocorticoid/genetics
KW - Annexin A1/genetics
KW - Chlormadinone Acetate/pharmacology
KW - Contraceptives, Oral, Synthetic/pharmacology
KW - Cyclooxygenase 2/genetics
KW - Dexamethasone/pharmacology
KW - Dysmenorrhea/drug therapy/metabolism/pathology
KW - Endometrium/drug effects/metabolism
KW - Interleukin-1beta/pharmacology
KW - Leukotriene B4/metabolism
KW - Leukotriene C4/metabolism
KW - Prostaglandins/biosynthesis
KW - Receptors, Progesterone/genetics
KW - Adult
KW - Humans
KW - Female
KW - Adolescent
KW - Young Adult
KW - Organ Culture Techniques
KW - RNA, Messenger/metabolism
KW - Dinoprost/metabolism
KW - Glucocorticoids/pharmacology
KW - Receptors, Glucocorticoid/genetics
KW - Annexin A1/genetics
KW - Chlormadinone Acetate/pharmacology
KW - Contraceptives, Oral, Synthetic/pharmacology
KW - Cyclooxygenase 2/genetics
KW - Dexamethasone/pharmacology
KW - Dysmenorrhea/drug therapy/metabolism/pathology
KW - Endometrium/drug effects/metabolism
KW - Interleukin-1beta/pharmacology
KW - Leukotriene B4/metabolism
KW - Leukotriene C4/metabolism
KW - Prostaglandins/biosynthesis
KW - Receptors, Progesterone/genetics
M3 - SCORING: Journal article
VL - 98
SP - 1017
EP - 1022
JO - FERTIL STERIL
JF - FERTIL STERIL
SN - 0015-0282
IS - 4
M1 - 4
ER -