Research ExplorerPublicationsAcute hepatitis as a prequel to very severe aplastic anemia

Acute hepatitis as a prequel to very severe aplastic anemia

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Acute hepatitis as a prequel to very severe aplastic anemia. / Weiler-Normann, Christina; Hartl, Johannes; Weidemann, Sören; von Pein, Ute-Marie; Fiedler, Walter; Schramm, Christoph; Brinkert, Florian; Kröger, Nicolaus; Christopeit, Maximilian.

In: Z GASTROENTEROL, Vol. 56, No. 1, 01.2018, p. 51-54.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Weiler-Normann, C, Hartl, J, Weidemann, S, von Pein, U-M, Fiedler, W, Schramm, C, Brinkert, F, Kröger, N & Christopeit, M 2018, 'Acute hepatitis as a prequel to very severe aplastic anemia', Z GASTROENTEROL, vol. 56, no. 1, pp. 51-54. https://doi.org/10.1055/s-0043-121737

APA

Weiler-Normann, C., Hartl, J., Weidemann, S., von Pein, U-M., Fiedler, W., Schramm, C., Brinkert, F., Kröger, N., & Christopeit, M. (2018). Acute hepatitis as a prequel to very severe aplastic anemia. Z GASTROENTEROL, 56(1), 51-54. https://doi.org/10.1055/s-0043-121737

Vancouver

Weiler-Normann C, Hartl J, Weidemann S, von Pein U-M, Fiedler W, Schramm C et al. Acute hepatitis as a prequel to very severe aplastic anemia. Z GASTROENTEROL. 2018 Jan;56(1):51-54. https://doi.org/10.1055/s-0043-121737

Bibtex

@article{84eab29091924666a8eab3545edcb074,
title = "Acute hepatitis as a prequel to very severe aplastic anemia",
abstract = "Severe aplastic anemia is a rare and potentially life-threatening disease of the bone marrow often requiring allogeneic hematopoietic stem cell transplantation. Pathogenesis of the disease can vary and often remains enigmatic. Occasionally, severe aplastic anemia is associated with prior severe acute hepatitis. Differential diagnosis of acute non-viral hepatitis challenges the physician as pathogenesis remains unclear.We here present a case of a young patient presenting with acute hepatitis followed by severe aplastic anemia successfully treated with allogeneic hematopoietic stem cell transplantation. Due to immunosuppressive treatment with azathioprine for acute hepatitis of putative autoimmune pathogenesis and coincident infection with parvovirus B19, diagnosis of the sequential disease of acute hepatitis followed by severe aplastic anemia was complicated. We discuss the caveats and present a review of the literature.",
keywords = "Journal Article",
author = "Christina Weiler-Normann and Johannes Hartl and S{\"o}ren Weidemann and {von Pein}, Ute-Marie and Walter Fiedler and Christoph Schramm and Florian Brinkert and Nicolaus Kr{\"o}ger and Maximilian Christopeit",
note = "{\textcopyright} Georg Thieme Verlag KG Stuttgart · New York.",
year = "2018",
month = jan,
doi = "10.1055/s-0043-121737",
language = "English",
volume = "56",
pages = "51--54",
journal = "Z GASTROENTEROL",
issn = "0044-2771",
publisher = "Karl Demeter Verlag GmbH",
number = "1",

}

RIS

TY - JOUR

T1 - Acute hepatitis as a prequel to very severe aplastic anemia

AU - Weiler-Normann, Christina

AU - Hartl, Johannes

AU - Weidemann, Sören

AU - von Pein, Ute-Marie

AU - Fiedler, Walter

AU - Schramm, Christoph

AU - Brinkert, Florian

AU - Kröger, Nicolaus

AU - Christopeit, Maximilian

N1 - © Georg Thieme Verlag KG Stuttgart · New York.

PY - 2018/1

Y1 - 2018/1

N2 - Severe aplastic anemia is a rare and potentially life-threatening disease of the bone marrow often requiring allogeneic hematopoietic stem cell transplantation. Pathogenesis of the disease can vary and often remains enigmatic. Occasionally, severe aplastic anemia is associated with prior severe acute hepatitis. Differential diagnosis of acute non-viral hepatitis challenges the physician as pathogenesis remains unclear.We here present a case of a young patient presenting with acute hepatitis followed by severe aplastic anemia successfully treated with allogeneic hematopoietic stem cell transplantation. Due to immunosuppressive treatment with azathioprine for acute hepatitis of putative autoimmune pathogenesis and coincident infection with parvovirus B19, diagnosis of the sequential disease of acute hepatitis followed by severe aplastic anemia was complicated. We discuss the caveats and present a review of the literature.

AB - Severe aplastic anemia is a rare and potentially life-threatening disease of the bone marrow often requiring allogeneic hematopoietic stem cell transplantation. Pathogenesis of the disease can vary and often remains enigmatic. Occasionally, severe aplastic anemia is associated with prior severe acute hepatitis. Differential diagnosis of acute non-viral hepatitis challenges the physician as pathogenesis remains unclear.We here present a case of a young patient presenting with acute hepatitis followed by severe aplastic anemia successfully treated with allogeneic hematopoietic stem cell transplantation. Due to immunosuppressive treatment with azathioprine for acute hepatitis of putative autoimmune pathogenesis and coincident infection with parvovirus B19, diagnosis of the sequential disease of acute hepatitis followed by severe aplastic anemia was complicated. We discuss the caveats and present a review of the literature.

KW - Journal Article

U2 - 10.1055/s-0043-121737

DO - 10.1055/s-0043-121737

M3 - SCORING: Journal article

C2 - 29316578

VL - 56

SP - 51

EP - 54

JO - Z GASTROENTEROL

JF - Z GASTROENTEROL

SN - 0044-2771

IS - 1

ER -