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A new inverse regression model applied to radiation biodosimetry

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A new inverse regression model applied to radiation biodosimetry. / Higueras, Manuel; Puig, Pedro; Ainsbury, Elizabeth A; Rothkamm, Kai.

In: P ROY SOC A-MATH PHY, Vol. 471, No. 2174, 08.02.2015, p. 20140588.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Higueras, M, Puig, P, Ainsbury, EA & Rothkamm, K 2015, 'A new inverse regression model applied to radiation biodosimetry', P ROY SOC A-MATH PHY, vol. 471, no. 2174, pp. 20140588. https://doi.org/10.1098/rspa.2014.0588

APA

Higueras, M., Puig, P., Ainsbury, E. A., & Rothkamm, K. (2015). A new inverse regression model applied to radiation biodosimetry. P ROY SOC A-MATH PHY, 471(2174), 20140588. https://doi.org/10.1098/rspa.2014.0588

Vancouver

Higueras M, Puig P, Ainsbury EA, Rothkamm K. A new inverse regression model applied to radiation biodosimetry. P ROY SOC A-MATH PHY. 2015 Feb 8;471(2174):20140588. https://doi.org/10.1098/rspa.2014.0588

Bibtex

@article{410bde018d104fe7ba29505e04543f73,
title = "A new inverse regression model applied to radiation biodosimetry",
abstract = "Biological dosimetry based on chromosome aberration scoring in peripheral blood lymphocytes enables timely assessment of the ionizing radiation dose absorbed by an individual. Here, new Bayesian-type count data inverse regression methods are introduced for situations where responses are Poisson or two-parameter compound Poisson distributed. Our Poisson models are calculated in a closed form, by means of Hermite and negative binomial (NB) distributions. For compound Poisson responses, complete and simplified models are provided. The simplified models are also expressible in a closed form and involve the use of compound Hermite and compound NB distributions. Three examples of applications are given that demonstrate the usefulness of these methodologies in cytogenetic radiation biodosimetry and in radiotherapy. We provide R and SAS codes which reproduce these examples.",
author = "Manuel Higueras and Pedro Puig and Ainsbury, {Elizabeth A} and Kai Rothkamm",
year = "2015",
month = feb,
day = "8",
doi = "10.1098/rspa.2014.0588",
language = "English",
volume = "471",
pages = "20140588",
journal = "P ROY SOC A-MATH PHY",
issn = "1364-5021",
publisher = "Royal Society of London",
number = "2174",

}

RIS

TY - JOUR

T1 - A new inverse regression model applied to radiation biodosimetry

AU - Higueras, Manuel

AU - Puig, Pedro

AU - Ainsbury, Elizabeth A

AU - Rothkamm, Kai

PY - 2015/2/8

Y1 - 2015/2/8

N2 - Biological dosimetry based on chromosome aberration scoring in peripheral blood lymphocytes enables timely assessment of the ionizing radiation dose absorbed by an individual. Here, new Bayesian-type count data inverse regression methods are introduced for situations where responses are Poisson or two-parameter compound Poisson distributed. Our Poisson models are calculated in a closed form, by means of Hermite and negative binomial (NB) distributions. For compound Poisson responses, complete and simplified models are provided. The simplified models are also expressible in a closed form and involve the use of compound Hermite and compound NB distributions. Three examples of applications are given that demonstrate the usefulness of these methodologies in cytogenetic radiation biodosimetry and in radiotherapy. We provide R and SAS codes which reproduce these examples.

AB - Biological dosimetry based on chromosome aberration scoring in peripheral blood lymphocytes enables timely assessment of the ionizing radiation dose absorbed by an individual. Here, new Bayesian-type count data inverse regression methods are introduced for situations where responses are Poisson or two-parameter compound Poisson distributed. Our Poisson models are calculated in a closed form, by means of Hermite and negative binomial (NB) distributions. For compound Poisson responses, complete and simplified models are provided. The simplified models are also expressible in a closed form and involve the use of compound Hermite and compound NB distributions. Three examples of applications are given that demonstrate the usefulness of these methodologies in cytogenetic radiation biodosimetry and in radiotherapy. We provide R and SAS codes which reproduce these examples.

U2 - 10.1098/rspa.2014.0588

DO - 10.1098/rspa.2014.0588

M3 - SCORING: Journal article

C2 - 25663804

VL - 471

SP - 20140588

JO - P ROY SOC A-MATH PHY

JF - P ROY SOC A-MATH PHY

SN - 1364-5021

IS - 2174

ER -