ID: 72399
Vera Freytag
Publications
- 2024
The Histogenetic Origin of Malignant Cells Predicts Their Susceptibility towards Synthetic Lethality Utilizing the TK.007 System
Pallasch, F. B., Freytag, V., Kriegs, M., Gatzemeier, D., Mair, T., Voss, H., Riecken, K., Dawood, M., Fehse, B., Efferth, T., Schlüter, H. & Schumacher, U., 19.06.2024, In: CANCERS. 16, 12, 2278.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of ex vivo bioluminescence imaging, Alu-qPCR and histology for the quantification of spontaneous lung and bone metastases in subcutaneous xenograft mouse models
Haider, M-T., Freytag, V., Krause, L., Spethmann, T., Gosau, T., Beine, M. C., Knies, C., Schröder-Schwarz, J., Horn, M., Riecken, K. & Lange, T., 04.2024, In: CLIN EXP METASTAS. 41, 2, p. 103-115 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis, hypoxia, EMT and mitochondria-related pathways in colorectal cancer
Everest-Dass, A., Nersisyan, S., Maar, H., Novosad, V., Schröder-Schwarz, J., Freytag, V., Stuke, J. L., Beine, M. C., Schiecke, A., Haider, M-T., Kriegs, M., Elakad, O., Bohnenberger, H., Conradi, L-C., Raygorodskaya, M., Krause, L., von Itzstein, M., Tonevitsky, A., Schumacher, U., Maltseva, D., Wicklein, D. & Lange, T., 01.2024, In: MOL ONCOL. 18, 1, p. 62-90 29 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription
Gorodetska, I., Offermann, A., Püschel, J., Lukiyanchuk, V., Gaete, D., Kurzyukova, A., Freytag, V., Haider, M-T., Fjeldbo, C. S., Di Gaetano, S., Schwarz, F. M., Patil, S., Borkowetz, A., Erb, H. H. H., Baniahmad, A., Mircetic, J., Lyng, H., Löck, S., Linge, A., Lange, T., Knopf, F., Wielockx, B., Krause, M., Perner, S. & Dubrovska, A., 2024, In: THERANOSTICS. 14, 2, p. 714-737 24 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Identification of potential classes of glycoligands mediating dynamic endothelial adhesion of human tumor cells
Starzonek, S., Maar, H., Mereiter, S., Freytag, V., Haider, M-T., Riecken, K., Huang, Y-L., Jacob, F., Wicklein, D., Schumacher, U. & Lange, T., 06.10.2023, In: GLYCOBIOLOGY. 33, 8, p. 637-650 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dynamics of CXCR4 positive circulating tumor cells in prostate cancer patients during radiotherapy
Klusa, D., Lohaus, F., Franken, A., Baumbach, M., Cojoc, M., Dowling, P., Linge, A., Offermann, A., Löck, S., Hušman, D., Rivandi, M., Polzer, B., Freytag, V., Lange, T., Neubauer, H., Kücken, M., Perner, S., Hölscher, T., Dubrovska, A., Krause, M., Kurth, I., Baumann, M. & Peitzsch, C., 15.06.2023, In: INT J CANCER. 152, 12, p. 2639-2654 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficacy of zoledronic acid for the elimination of disseminated tumor cells in a clinically relevant, spontaneously metastatic prostate cancer xenograft model
Böckelmann, L. C., Freytag, V., Ahlers, A-K., Maar, H., Gosau, T., Baranowsky, A., Schmitz, R., Pantel, K., Schumacher, U., Haider, M-T. & Lange, T., 06.2023, In: BONE. 171, p. 116741Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo
Genduso, S., Freytag, V., Schetler, D., Kirchner, L., Schiecke, A., Maar, H., Wicklein, D., Gebauer, F., Bröker, K., Stürken, C., Milde-Langosch, K., Oliveira-Ferrer, L., Ricklefs, F. L., Ewald, F., Wolters-Eisfeld, G., Riecken, K., Unrau, L., Krause, L., Bohnenberger, H., Offermann, A., Perner, S., Sebens, S., Lamszus, K., Diehl, L., Linder, S., Jücker, M., Schumacher, U. & Lange, T., 17.03.2023, In: J HEMATOL ONCOL. 16, 1, 23.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Activation of CD44/PAK1/AKT signaling promotes resistance to FGFR1 inhibition in squamous-cell lung cancer
Elakad, O., Häupl, B., Labitzky, V., Yao, S., Küffer, S., von Hammerstein-Equord, A., Danner, B. C., Jücker, M., Urlaub, H., Lange, T., Ströbel, P., Oellerich, T. & Bohnenberger, H., 19.07.2022, In: NPJ PRECIS ONCOL. 6, 1, 52.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tumor cell E-selectin ligands determine partialefficacy of bortezomib on spontaneous lung metastasis formation of solid human tumors in vivo
Lange, T., Valentiner, U., Wicklein, D., Maar, H., Labitzky, V., Ahlers, A-K., Starzonek, S., Genduso, S., Staffeldt, L., Pahlow, C., Dück, A-M., Stürken, C., Baranowsky, A., Bauer, A. T., Bulk, E., Schwab, A., Riecken, K., Börnchen, C., Kiefmann, R., Abraham, V., DeLisser, H. M., Gemoll, T., Habermann, J. K., Block, A., Pantel, K. & Schumacher, U., 06.04.2022, In: MOL THER. 30, 4, p. 1536-1552 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo
Oh-Hohenhorst, S. J., Tilki, D., Ahlers, A-K., Suling, A., Hahn, O., Tennstedt, P., Matuszcak, C., Maar, H., Labitzky, V., Hanika, S., Starzonek, S., Baumgart, S., Johnsen, S. A., Kluth, M., Sirma, H., Simon, R., Sauter, G., Huland, H., Schumacher, U. & Lange, T., 01.2022, In: CANCER GENE THER. 29, 1, p. 49-61 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of Spontaneous Bone Metastases of Solid Human Tumor Xenografts in Mice
Freytag, V., Valentiner, U. & Lange, T., 2022, Bioluminescence: Methods and Protocols. Kim, S-B. (ed.). 4 ed. New York, NY: Humana Press, Vol. 1. p. 317-325 9 p. (Methods in Molecular Biology; vol. 2524).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2021
Molecular characteristics and tumorigenicity of ascites-derived tumor cells: mitochondrial oxidative phosphorylation as a novel therapy target in ovarian cancer
Ding, Y., Labitzky, V., Legler, K., Qi, M., Schumacher, U., Schmalfeldt, B., Stürken, C. & Oliveira-Ferrer, L., 12.2021, In: MOL ONCOL. 15, 12, p. 3578-3595 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival
Huang, Y-L., Liang, C-Y., Labitzky, V., Ritz, D., Oliveira, T., Cumin, C., Estermann, M., Lange, T., Everest-Dass, A. V. & Jacob, F., 22.10.2021, In: ISCIENCE. 24, 10, 103168.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Opposing prognostic relevance of junction plakoglobin in distinct prostate cancer patient subsets
Spethmann, T., Böckelmann, L. C., Labitzky, V., Ahlers, A-K., Schröder-Schwarz, J., Bonk, S., Simon, R., Sauter, G., Huland, H., Kypta, R., Schumacher, U. & Lange, T., 07.2021, In: MOL ONCOL. 15, 7, p. 1956-1969 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy
Mukha, A., Kahya, U., Linge, A., Chen, O., Löck, S., Lukiyanchuk, V., Richter, S., Alves, T. C., Peitzsch, M., Telychko, V., Skvortsov, S., Negro, G., Aschenbrenner, B., Skvortsova, I-I., Mirtschink, P., Lohaus, F., Hölscher, T., Neubauer, H., Rivandi, M., Labitzky, V., Lange, T., Franken, A., Behrens, B., Stoecklein, N. H., Toma, M., Sommer, U., Zschaeck, S., Rehm, M., Eisenhofer, G., Schwager, C., Abdollahi, A., Groeben, C., Kunz-Schughart, L. A., Baretton, G. B., Baumann, M., Krause, M., Peitzsch, C. & Dubrovska, A., 2021, In: THERANOSTICS. 11, 16, p. 7844-7868 25 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Use of Electrical Impedance Spectroscopy to Distinguish Cancer from Normal Tissues with a Four Electrode Terminal Setup
Teixeira, V. S., Labitzky, V., Schumacher, U. & Krautschneider, W. H., 11.2020, In: Current Directions in Biomedical Engineering. 2020, 6, p. 341 - 344Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Xenograft-derived mRNA/miR and protein interaction networks of systemic dissemination in human prostate cancer
Lange, T., Samatov, T. R., Galatenko, V. V., Steffen, P., von Kriegstein, H., Spethmann, T., Wicklein, D., Maar, H., Kupfernagel, K., Labitzky, V., Hanika, S., Starzonek, S., Ahlers, A-K., Riecken, K., Simon, R., Polonski, A., Sauter, G., Schlomm, T., Huland, H., Johnsen, S. A., Schlüter, H., Tonevitsky, A. G. & Schumacher, U., 09.2020, In: EUR J CANCER. 137, p. 93-107 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions
Starzonek, S., Maar, H., Labitzky, V., Wicklein, D., Rossdam, C., Buettner, F. F. R., Wolters-Eisfeld, G., Guengoer, C., Wagener, C., Schumacher, U. & Lange, T., 20.08.2020, In: GLYCOBIOLOGY. 30, 9, p. 695-709 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The initial engraftment of tumor cells is critical for the future growth pattern: a mathematical study based on simulations and animal experiments
Hoffmann, B., Lange, T., Labitzky, V., Riecken, K., Wree, A., Schumacher, U. & Wedemann, G., 05.06.2020, In: BMC CANCER. 20, 1, p. 524Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Modeling Spontaneous Bone Metastasis Formation of Solid Human Tumor Xenografts in Mice
Labitzky, V., Baranowsky, A., Maar, H., Hanika, S., Starzonek, S., Ahlers, A-K., Stübke, K., Koziolek, E. J., Heine, M., Schäfer, P., Windhorst, S., Jücker, M., Riecken, K., Amling, M., Schinke, T., Schumacher, U., Valentiner, U. & Lange, T., 07.02.2020, In: CANCERS. 12, 2Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Electrical Impedance Spectroscopy for Characterization of Prostate PC-3 and DU 145 Cancer Cells
Teixeira, V. S., Barth, T., Labitzky, V., Schumacher, U. & Krautschneider, W., 07.2019, In: Conf Proc IEEE Eng Med Biol Soc. 2019, p. 6485-6489 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Prognostic impact of transcription factor Fra-1 in ER-positive breast cancer: contribution to a metastatic phenotype through modulation of tumor cell adhesive properties
Oliveira-Ferrer, L., Kürschner, M., Labitzky, V., Wicklein, D., Müller, V., Lüers, G., Schumacher, U., Milde-Langosch, K. & Schröder, C., 10.2015, In: J CANCER RES CLIN. 141, 10, p. 1715-26Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
E- and p-selectins are essential for repopulation of chronic myelogenous and chronic eosinophilic leukemias in a scid mouse xenograft model
Wicklein, D., Schmidt, A., Labitzky, V., Ullrich, S., Valent, P. & Schumacher, U., 01.01.2013, In: PLOS ONE. 8, 7, p. e70139Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review