Dr. ID: 58782
Harriet Wikman-Kocher
Publications
- 2024
Frequency and Prognostic Value of Circulating Tumor Cells in Cancer of Unknown Primary
Pouyiourou, M., Bochtler, T., Coith, C., Wikman, H., Kraft, B., Hielscher, T., Stenzinger, A., Riethdorf, S., Pantel, K. & Krämer, A., 04.01.2024, In: CLIN CHEM. 70, 1, p. 297-306 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer
Prokakis, E., Jansari, S., Boshnakovska, A., Wiese, M., Kusch, K., Kramm, C., Dullin, C., Rehling, P., Glatzel, M., Pantel, K., Wikman, H., Johnsen, S. A., Gallwas, J. & Wegwitz, F., 28.09.2023, In: CELL DEATH DIS. 14, 9, p. 641Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection and Monitoring of Tumor-Derived Mutations in Circulating Tumor DNA Using the UltraSEEK Lung Panel on the MassARRAY System in Metastatic Non-Small Cell Lung Cancer Patients
Leest, P. V. D., Janning, M., Rifaela, N., Azpurua, M. L. A., Kropidlowski, J., Loges, S., Lozano, N., Sartori, A., Irwin, D., Lamy, P-J., Hiltermann, T. J. N., Groen, H. J. M., Pantel, K., Kempen, L. C. V., Wikman, H. & Schuuring, E., 29.08.2023, In: INT J MOL SCI. 24, 17, 13390.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Label Efficient Classification in Liquid Biopsy Data by Self-supervision
Husseini, H., Nielsen, M., Pantel, K., Wikman, H., Riethdorf, S. & Werner, R., 02.06.2023, Bildverarbeitung für die Medizin 2023: Proceedings, German Workshop on Medical Image Computing, Braunschweig, July 2-4, 2023. Deserno, T. M., Handels, H., Maier, A., Maier-Hein, K., Palm, C. & Tolxdorff, T. (eds.). 1 ed. Springer Vieweg, p. 261-266 6 p. (Informatik aktuell).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Comparative evaluation of PD-L1 expression in cytology imprints, circulating tumour cells and tumour tissue in non-small cell lung cancer patients
Abdo, M., Belloum, Y., Heigener, D., Welker, L., von Weihe, S., Schmidt, M., Heuer-Olewinski, N., Watermann, I., Szewczyk, M., Kropidlowski, J., Pereira-Veiga, T., Elmas, H., Perner, S., Steurer, S., Wikman, H., Pantel, K. & Reck, M., 05.2023, In: MOL ONCOL. 17, 5, p. 737-746 10 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
The role of the desmosomal protein desmocollin 2 in tumour progression in triple negative breast cancer patients
Reimer, F., Bryan, S., Legler, K., Karn, T., Eppenberger-Castori, S., Matschke, J., Pereira-Veiga, T., Wikman, H., Witzel, I., Müller, V., Schmalfeldt, B., Milde-Langosch, K., Schumacher, U., Stürken, C. & Oliveira-Ferrer, L., 16.03.2023, In: CANCER CELL INT. 23, 1, p. 47Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Peripheral and Portal Venous KRAS ctDNA Detection as Independent Prognostic Markers of Early Tumor Recurrence in Pancreatic Ductal Adenocarcinoma
Nitschke, C., Markmann, B., Walter, P., Badbaran, A., Tölle, M., Kropidlowski, J., Belloum, Y., Goetz, M. R., Bardenhagen, J., Stern, L., Tintelnot, J., Schönlein, M., Sinn, M., van der Leest, P., Simon, R., Heumann, A., Izbicki, J. R., Pantel, K., Wikman, H. & Uzunoglu, F. G., 01.03.2023, In: CLIN CHEM. 69, 3, p. 295-307 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Circulating Cancer Associated Macrophage-like Cells as a Potential New Prognostic Marker in Pancreatic Ductal Adenocarcinoma
Nitschke, C., Markmann, B., Konczalla, L., Kropidlowski, J., Pereira-Veiga, T., Scognamiglio, P., Schönrock, M., Sinn, M., Tölle, M., Izbicki, J., Pantel, K., Uzunoglu, F. G. & Wikman, H., 17.11.2022, In: BIOMEDICINES. 10, 11, 2955.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating tumor cells and extracellular vesicles as liquid biopsy markers in neuro-oncology: prospects and limitations
Westphal, M., Pantel, K., Ricklefs, F. L., Maire, C., Riethdorf, S., Mohme, M., Wikman, H. & Lamszus, K., 11.2022, In: NEURO-ONCOL ADV. 4, Suppl 2, p. ii45-ii52Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical applications and utility of cell-free DNA-based liquid biopsy analyses in cervical cancer and its precursor lesions
Herbst, J., Pantel, K., Effenberger, K. & Wikman, H., 11.2022, In: BRIT J CANCER. 127, 8, p. 1403-1410 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Clinical determinants impacting overall survival of patients with operable brain metastases from non-small cell lung cancer
Piffko, A., Asey, B., Dührsen, L., Ristow, I., Salamon, J., Wikman, H., Maire, C. L., Lamszus, K., Westphal, M., Sauvigny, T. & Mohme, M., 20.10.2022, In: FRONT ONCOL. 12, 951805.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of RARRES1 Expression on Circulating Tumor Cells as Unfavorable Prognostic Marker in Resected Pancreatic Ductal Adenocarcinoma Patients
Nitschke, C., Markmann, B., Tölle, M., Kropidlowski, J., Belloum, Y., Goetz, M. R., Schlüter, H., Kwiatkowski, M., Sinn, M., Izbicki, J., Pantel, K., Güngör, C., Uzunoglu, F. G. & Wikman, H., 10.09.2022, In: CANCERS. 14, 18, 4405.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating tumor cell-blood cell crosstalk: Biology and clinical relevance
Pereira-Veiga, T., Schneegans, S., Pantel, K. & Wikman, H., 30.08.2022, In: CELL REP. 40, 9, 111298.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Combined Liquid Biopsy Methylation Analysis of CADM1 and MAL in Cervical Cancer Patients
Leffers, M., Herbst, J., Kropidlowski, J., Prieske, K., Bohnen, A. L., Peine, S., Jaeger, A., Prieske, K., Goy, Y., Schmalfeldt, B., Pantel, K., Wölber, L., Effenberger, K. & Wikman, H., 16.08.2022, In: CANCERS. 14, 16, 3954.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression Patterns and Corepressor Function of Retinoic Acid-induced 2 in Prostate Cancer
Besler, K., Węglarz, A., Keller, L., von Amsberg, G., Bednarz-Knoll, N., Offermann, A., Stoupiec, S., Eltze, E., Semjonow, A., Boettcher, L., Schneegans, S., Perner, S., Hauch, S., Todenhöfer, T., Peine, S., Pantel, K., Wikman, H. & Werner, S., 03.07.2022, In: CLIN CHEM. 68, 7, p. 973-983 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism
Monteiro, C., Miarka, L., Perea-García, M., Priego, N., García-Gómez, P., Álvaro-Espinosa, L., de Pablos-Aragoneses, A., Yebra, N., Retana, D., Baena, P., Fustero-Torre, C., Graña-Castro, O., Troulé, K., Caleiras, E., Tezanos, P., Muela, P., Cintado, E., Trejo, J. L., Sepúlveda, J. M., González-León, P., Jiménez-Roldán, L., Moreno, L. M., Esteban, O., Pérez-Núñez, Á., Hernández-Lain, A., Mazarico Gallego, J., Ferrer, I., Suárez, R., Garrido-Martín, E. M., Paz-Ares, L., Dalmasso, C., Cohen-Jonathan Moyal, E., Siegfried, A., Hegarty, A., Keelan, S., Varešlija, D., Young, L. S., Mohme, M., Goy, Y., Wikman, H., Fernández-Alén, J., Blasco, G., Alcázar, L., Cabañuz, C., Grivennikov, S. I., Ianus, A., Shemesh, N., Faria, C. C., Lee, R., Lorigan, P., Le Rhun, E., Weller, M., Soffietti, R., Bertero, L., Ricardi, U., Bosch-Barrera, J., Sais, E., Teixidor, E., Hernández-Martínez, A., Calvo, A., Aristu, J., Martin, S. M., Gonzalez, A., Adler, O., Erez, N. & Valiente, M., 04.2022, In: NAT MED. 28, 4, p. 752-765 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Decellularized In Vitro Capillaries for Studies of Metastatic Tendency and Selection of Treatment
Huttala, O., Loreth, D., Staff, S., Tanner, M., Wikman, H. & Ylikomi, T., 26.01.2022, In: BIOMEDICINES. 10, 2, 271.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Spine Metastases in Immunocompromised Mice after Intracardiac Injection of MDA-MB-231-SCP2 Breast Cancer Cells
Brylka, L., Jähn-Rickert, K., Baranowsky, A., Neven, M., Horn, M., Yorgan, T., Wikman, H., Werner, S., Lübke, A., Amling, M., Busse, B., Pantel, K. & Schinke, T., 22.01.2022, In: CANCERS. 14, 3, 556.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tumor-Stroma Interaction in PDAC as a New Approach for Liquid Biopsy and its Potential Clinical Implications
Götze, J., Nitschke, C., Uzunoglu, F. G., Pantel, K., Sinn, M. & Wikman, H., 2022, In: FRONT CELL DEV BIOL. 10, 918795.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2021
Decreased PRC2 activity supports the survival of basal-like breast cancer cells to cytotoxic treatments
Mieczkowska, I. K., Pantelaiou-Prokaki, G., Prokakis, E., Schmidt, G. E., Müller-Kirschbaum, L. C., Werner, M., Sen, M., Velychko, T., Jannasch, K., Dullin, C., Napp, J., Pantel, K., Wikman, H., Wiese, M., Kramm, C. M., Alves, F. & Wegwitz, F., 29.11.2021, In: CELL DEATH DIS. 12, 12, 1118.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
P02.01 A strategy to personalize the use of radiation in patients with brain metastasis based on S100A9-mediated resistance
Miarka, L., Monteiro, C., Dalmasso, C., Yebra, N., Fustero-Torre, C., Hegarty, A., Keelan, S., Goy, Y., Mohme, M., Caleiras, E., Vareslija, D., Young, L., Soffietti, R., Fernández-Alén, J., Blasco, G., Alcázar, L., Sepúlveda, J., Pérez, A., Lain, A., Siegfried, A., Wikman, H., Cohen-Jonathan Moyal, E. & Valiente, M., 01.09.2021, In: NEURO-ONCOLOGY. 23, Supplement_2, p. ii17-ii17Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
Emerging Insights into Keratin 16 Expression during Metastatic Progression of Breast Cancer
Elazezy, M., Schwentesius, S., Stegat, L., Wikman, H., Werner, S., Mansour, W. Y., Failla, A. V., Peine, S., Müller, V., Thiery, J. P., Ebrahimi Warkiani, M., Pantel, K. & Joosse, S. A., 31.07.2021, In: CANCERS. 13, 15, 3869.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis
Loreth, D., Schuette, M., Zinke, J., Mohme, M., Piffko, A., Schneegans, S., Stadler, J., Janning, M., Loges, S., Joosse, S. A., Lamszus, K., Westphal, M., Müller, V., Glatzel, M., Matschke, J., Gebhardt, C., Schneider, S. W., Belczacka, I., Volkmer, B., Greinert, R., Yaspo, M-L., Harter, P. N., Pantel, K. & Wikman, H., 29.06.2021, In: INT J MOL SCI. 22, 13, 6993.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Proficiency Testing to Assess Technical Performance for CTC-Processing and Detection Methods in CANCER-ID
Neves, R. P. L., Ammerlaan, W., Andree, K. C., Bender, S., Cayrefourcq, L., Driemel, C., Koch, C., Luetke-Eversloh, M. V., Oulhen, M., Rossi, E., Alix-Panabières, C., Betsou, F., Farace, F., Riethdorf, S., Schlange, T., Wikman, H., Zamarchi, R., Pantel, K., Terstappen, L. W. M. M., Stoecklein, N. H. & CANCER-ID Consortium, 31.03.2021, In: CLIN CHEM. 67, 4, p. 631-641 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions
Pantano, F., Croset, M., Driouch, K., Bednarz-Knoll, N., Iuliani, M., Ribelli, G., Bonnelye, E., Wikman, H., Geraci, S., Bonin, F., Simonetti, S., Vincenzi, B., Hong, S. S., Sousa, S., Pantel, K., Tonini, G., Santini, D. & Clézardin, P., 02.2021, In: ONCOGENE. 40, 7, p. 1284-1299 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond
Keller, L., Belloum, Y., Wikman, H. & Pantel, K., 01.2021, In: BRIT J CANCER. 124, 2, p. 345-358 14 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2020
Discovery of Targetable Genetic Alterations in NSCLC Patients with Different Metastatic Patterns Using a MassARRAY-Based Circulating Tumor DNA Assay
Belloum, Y., Janning, M., Mohme, M., Simon, R., Kropidlowski, J., Sartori, A., Irwin, D., Westphal, M., Lamszus, K., Loges, S., Riethdorf, S., Pantel, K. & Wikman, H., 22.10.2020, In: CELLS-BASEL. 9, 11, E2337.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization against PARP1 Inhibition in a Replication-Dependent Manner
Rieckhoff, J., Meyer, F., Classen, S., Zielinski, A., Riepen, B., Wikman, H., Petersen, C., Rothkamm, K., Borgmann, K. & Parplys, A. C., 29.09.2020, In: CANCERS. 12, 10Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ALCAM contributes to brain metastasis formation in non-small-cell lung cancer through interaction with the vascular endothelium
Münsterberg, J., Loreth, D., Brylka, L., Werner, S., Karbanova, J., Gandrass, M., Schneegans, S., Besler, K., Hamester, F., Robador, J. R., Bauer, A. T., Werner Schneider, S., Wrage, M., Lamszus, K., Matschke, J., Vashist, Y., Uzunoglu, G., Steurer, S., Horst, A. K., Oliveira-Ferrer, L., Glatzel, M., Schinke, T., Corbeil, D., Pantel, K., Maire, C. & Wikman, H., 07.07.2020, In: NEURO-ONCOLOGY. 22, 7, p. 955-966 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pre-analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients
Schneegans, S., Lück, L., Besler, K., Bluhm, L., Stadler, J-C., Staub, J., Greinert, R., Volkmer, B., Kubista, M., Gebhardt, C., Sartori, A., Irwin, D., Serkkola, E., Af Hällström, T., Lianidou, E., Sprenger-Haussels, M., Hussong, M., Mohr, P., Schneider, S. W., Shaffer, J., Pantel, K. & Wikman, H., 05.2020, In: MOL ONCOL. 14, 5, p. 1001-1015 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer
Meyer, F., Becker, S., Classen, S., Parplys, A. C., Mansour, W. Y., Riepen, B., Timm, S., Ruebe, C., Jasin, M., Wikman, H., Petersen, C., Rothkamm, K. & Borgmann, K., 17.01.2020, In: CELLS-BASEL. 9, 1Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows
Lampignano, R., Neumann, M. H. D., Weber, S., Kloten, V., Herdean, A., Voss, T., Groelz, D., Babayan, A., Tibbesma, M., Schlumpberger, M., Chemi, F., Rothwell, D. G., Wikman, H., Galizzi, J-P., Bergheim, I. R., Russnes, H., Mussolin, B., Bonin, S., Voigt, C., Musa, H., Pinzani, P., Lianidou, E., Brady, G., Speicher, M. R., Pantel, K., Betsou, F., Schuuring, E., Kubista, M., Ammerlaan, W., Sprenger-Haussels, M., Schlange, T., Heitzer, E. & Innovative Medicines Initiative CANCER-ID Consortium, 01.01.2020, In: CLIN CHEM. 66, 1, p. 149-160 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Clonality of circulating tumor cells in breast cancer brain metastasis patients
Riebensahm, C., Joosse, S. A., Mohme, M., Hanssen, A., Matschke, J., Goy, Y., Witzel, I., Lamszus, K., Kropidlowski, J., Petersen, C., Kolb-Kokocinski, A., Sauer, S., Borgmann, K., Glatzel, M., Müller, V., Westphal, M., Riethdorf, S., Pantel, K. & Wikman, H., 03.09.2019, In: BREAST CANCER RES. 21, 1, p. 101Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
EPAC-lung: pooled analysis of circulating tumour cells in advanced non-small cell lung cancer
Lindsay, C. R., Blackhall, F. H., Carmel, A., Fernandez-Gutierrez, F., Gazzaniga, P., Groen, H. J. M., Hiltermann, T. J. N., Krebs, M. G., Loges, S., López-López, R., Muinelo-Romay, L., Pantel, K., Priest, L., Riethdorf, S., Rossi, E., Terstappen, L., Wikman, H., Soria, J-C., Farace, F., Renehan, A., Dive, C., Besse, B. & Michiels, S., 08.2019, In: EUR J CANCER. 117, p. 60-68 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors
Janning, M., Kobus, F., Babayan, A., Wikman, H., Velthaus, J-L., Bergmann, S., Schatz, S., Falk, M., Berger, L-A., Böttcher, L-M., Päsler, S., Gorges, T. M., O'Flaherty, L., Hille, C., Joosse, S. A., Simon, R., Tiemann, M., Bokemeyer, C., Reck, M., Riethdorf, S., Pantel, K. & Loges, S., 17.06.2019, In: CANCERS. 11, 6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
EGFR and HER3 expression in circulating tumor cells and tumor tissue from non-small cell lung cancer patients
Scharpenseel, H., Hanssen, A., Loges, S., Mohme, M., Bernreuther, C., Peine, S., Lamszus, K., Goy, Y., Petersen, C., Westphal, M., Glatzel, M., Riethdorf, S., Pantel, K. & Wikman, H., 15.05.2019, In: SCI REP-UK. 9, 1, p. 7406Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Frequency of Circulating Tumor Cells (CTC) in Patients with Brain Metastases: Implications as a Risk Assessment Marker in Oligo-Metastatic Disease
Hanssen, A., Riebensahm, C., Mohme, M., Joosse, S. A., Velthaus, J-L., Berger, L. A., Bernreuther, C., Glatzel, M., Loges, S., Lamszus, K., Westphal, M., Riethdorf, S., Pantel, K. & Wikman, H., 19.12.2018, In: CANCERS. 10, 12, p. E527Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification of a High-Level MET Amplification in CTCs and cfTNA of an ALK-Positive NSCLC Patient Developing Evasive Resistance to Crizotinib
Berger, L-A., Janning, M., Velthaus, J-L., Ben-Batalla, I., Schatz, S., Falk, M., Iglauer, P., Simon, R., Cao, R., Forcato, C., Manaresi, N., Bramlett, K., Buson, G., Hanssen, A., Tiemann, M., Sauter, G., Bokemeyer, C., Riethdorf, S., Reck, M., Pantel, K., Wikman, H. & Loges, S., 12.2018, In: J THORAC ONCOL. 13, 12, p. e243-e246Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical relevance of cytoskeleton associated proteins for ovarian cancer
Schiewek, J., Schumacher, U., Lange, T., Joosse, S. A., Wikman, H., Pantel, K., Mikhaylova, M., Kneussel, M., Linder, S., Schmalfeldt, B., Oliveira-Ferrer, L. & Windhorst, S., 11.2018, In: J CANCER RES CLIN. 144, 11, p. 2195-2205 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chromosomal Aberrations Associated with Sequential Steps of the Metastatic Cascade in Colorectal Cancer Patients
Joosse, S. A., Souche, F-R., Babayan, A., Gasch, C., Kerkhoven, R. M., Ramos, J., Fabre, J-M., Riethdorf, S., König, A., Wikman, H., Alix-Panabières, C. & Pantel, K., 10.2018, In: CLIN CHEM. 64, 10, p. 1505-1512 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stromal Caveolin-1 and Caveolin-2 Expression in Primary Tumors and Lymph Node Metastases
Gerstenberger, W., Wrage, M., Kettunen, E., Pantel, K., Anttila, S., Steurer, S. & Wikman, H., 2018, In: ANAL CELL PATHOL. 2018, p. 8651790Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Strong fascin expression promotes metastasis independent of its F-actin bundling activity
Heinz, L. S., Muhs, S., Schiewek, J., Grüb, S., Nalaskowski, M., Lin, Y-N., Wikman, H., Oliveira-Ferrer, L., Lange, T., Wellbrock, J., Konietzny, A., Mikhaylova, M. & Windhorst, S., 15.12.2017, In: ONCOTARGET. 8, 66, p. 110077-110091 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells
Babayan, A., Alawi, M., Gormley, M., Müller, V., Wikman, H., McMullin, R. P., Smirnov, D. A., Li, W., Geffken, M., Pantel, K. & Joosse, S. A., 22.08.2017, In: ONCOTARGET. 8, 34, p. 56066-56080 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases
Mohme, M., Riethdorf, S., Dreimann, M., Werner, S., Maire, C. L., Joosse, S. A., Bludau, F., Mueller, V., Neves, R. P. L., Stoecklein, N. H., Lamszus, K., Westphal, M., Pantel, K., Wikman, H. & Eicker, S. O., 03.08.2017, In: SCI REP-UK. 7, 1, p. 7196Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biology and clinical significance of circulating tumor cell subpopulations in lung cancer
O'Flaherty, L., Wikman, H. & Pantel, K., 08.2017, In: TRANSL LUNG CANCER R. 6, 4, p. 431-443 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Nanoplatforms for Circulating Tumor Cell Detection in Lung Cancer
Wikman, H. & Pantel, K., 08.2017, In: CLIN CHEM. 63, 8, p. 1318-1320 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cells
Lehtinen, L., Vainio, P., Wikman, H., Huhtala, H., Mueller, V., Kallioniemi, A., Pantel, K., Kronqvist, P., Kallioniemi, O., Carpèn, O. & Iljin, K., 04.2017, In: J PATHOL CLIN RES. 3, 2, p. 123-138 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of HYAL1 expression in primary breast cancer in the formation of brain metastases
Witzel, I., Marx, A. K., Müller, V., Wikman, H., Matschke, J., Schumacher, U., Stürken, C., Prehm, P., Laakmann, E., Schmalfeldt, B., Milde-Langosch, K. & Oliveira-Ferrer, L., 04.2017, In: BREAST CANCER RES TR. 162, 3, p. 427-438 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression
Hohensee, I., Chuang, H-N., Grottke, A., Werner, S., Schulte, A., Horn, S., Lamszus, K., Bartkowiak, K., Witzel, I., Westphal, M., Matschke, J., Glatzel, M., Jücker, M., Pukrop, T., Pantel, K. & Wikman, H., 01.2017, In: ONCOTARGET. 8, 4, p. 6155-6168Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Enumeration and molecular characterization of tumor cells in lung cancer patients using a novel in vivo device for capturing circulating tumor cells
Gorges, T. M., Penkalla, N., Schalk, T., Joosse, S., Riethdorf, S., Tucholski, J., Lucke, K., Wikman, H., Jackson, S. M., Brychter, N., von Ahsen, O., Schumann, C., Krahn, T. & Pantel, K., 01.05.2016, In: CLIN CANCER RES. 22, 9, p. 2197-206Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Potential Involvement of Jagged1 in Metastatic Progression of Human Breast Carcinomas
Bednarz-Knoll, N., Efstathiou, A., Gotzhein, F., Wikman, H., Mueller, V., Kang, Y. & Pantel, K., 02.2016, In: CLIN CHEM. 62, 2, p. 378-386Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells
Hvichia, G. E., Parveen, Z., Wagner, C., Janning, M., Quidde, J., Stein, A., Müller, V., Loges, S., Neves, R. P. L., Stoecklein, N. H., Wikman, H., Riethdorf, S., Pantel, K. & Gorges, T. M., 20.01.2016, In: INT J CANCER. 138, 12, p. 2894-904Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Breast cancer brain metastases:biology and new clinical perspectives
Witzel, I., Oliveira-Ferrer, L., Pantel, K., Müller, V. & Wikman, H., 19.01.2016, In: BREAST CANCER RES. 18, 1, p. 8Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of different CTC subpopulations in non-small cell lung cancer
Hanssen, A., Wagner, J., Gorges, T. M., Tänzer, A., Uzunoglu, F. G., Driemel, C., Stoecklein, N. H., Knoefel, W. T., Angenendt, S., Hauch, S., Atanackovic, D., Loges, S., Riethdorf, S., Pantel, K. & Wikman, H., 2016, In: SCI REP-UK. 6, p. 28010Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response
Bartkowiak, K., Kwiatkowski, M., Buck, F., Gorges, T. M., Nilse, L., Assmann, V., Andreas, A., Müller, V., Wikman, H., Riethdorf, S., Schlüter, H. & Pantel, K., 15.12.2015, In: CANCER RES. 75, 24, p. 5367-77 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases
Harter, P. N., Bernatz, S., Scholz, A., Zeiner, P. S., Zinke, J., Kiyose, M., Blasel, S., Beschorner, R., Senft, C., Bender, B., Ronellenfitsch, M. W., Wikman-Kocher, H., Glatzel, M., Meinhardt, M., Juratli, T. A., Steinbach, J. P., Plate, K. H., Wischhusen, J., Weide, B. & Mittelbronn, M., 12.2015, In: ONCOTARGET. 6, 38, p. 40836-40849Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression
Bednarz-Knoll, N., Nastały, P., Żaczek, A., Stoupiec, M., Riethdorf, S., Wikman-Kocher, H., Müller, V., Skokowski, J., Szade, J., Sejda, A., Wełnicka-Jaśkiewicz, M. & Pantel, K., 29.09.2015, In: ONCOTARGET. 6, 29, p. 26789-803 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of Circulating Tumor Cells in Non-Small Cell Lung Cancer
Hanssen, A., Loges, S., Pantel, K. & Wikman-Kocher, H., 22.09.2015, In: FRONT ONCOL. 5, p. Art. 207Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevance of βGal-βGalNAc-containing glycans and the enzymes involved in their synthesis for invasion and survival in breast cancer patients
Milde-Langosch, K., Schütze, D., Oliveira-Ferrer, L., Wikman-Kocher, H., Müller, V., Lebok, P., Pantel, K., Schröder, C., Witzel, I. & Schumacher, U., 06.2015, In: BREAST CANCER RES TR. 151, 3, p. 515-28 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification of HERC5 and its potential role in NSCLC progression
Wrage, M., Hagmann, W., Kemming, D., Uzunoglu, F. G., Riethdorf, S., Harms-Effenberger, K., Westphal, M., Lamszus, K., Kim, S-Z., Becker, N., Izbicki, J. R., Sandoval, J., Esteller, M., Pantel, K., Risch, A. & Wikman-Kocher, H., 15.05.2015, In: INT J CANCER. 136, 10, p. 2264-72Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells
Werner, S., Stamm, H., Pandjaitan, M., Kemming, D., Brors, B., Pantel, K. & Wikman, H., 2015, In: BMC CANCER. 15, 1, p. 896Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic acid induced 2
Werner, S., Brors, B., Eick, J., Marques, E., Pogenberg, V., Parret, A., Kemming, D., Wood, A. W., Edgren, H., Neubauer, H., Streichert, T., Riethdorf, S., Bedi, U., Baccelli, I., Jücker, M., Eils, R., Fehm, T., Trumpp, A., Johnsen, S. A., Klefstrom, J., Wilmanns, M., Müller, V., Pantel, K. & Wikman-Kocher, H., 2015, In: CANCER DISCOV. 5, 5, p. 506-19Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients
Eichelser, C., Stückrath, I., Müller, V., Milde-Langosch, K., Wikman-Kocher, H., Pantel, K. & Schwarzenbach, H., 30.10.2014, In: ONCOTARGET. 5, 20, p. 9650-63 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
LeBleu, V. S., O'Connell, J. T., Gonzalez Herrera, K. N., Wikman-Kocher, H., Pantel, K., Haigis, M. C., de Carvalho, F. M., Damascena, A., Domingos Chinen, L. T., Rocha, R. M., Asara, J. M. & Kalluri, R., 01.10.2014, In: NAT CELL BIOL. 16, 10, p. 992-1003Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients
Wikman-Kocher, H., Westphal, L., Schmid, F., Pollari, S., Kropidlowski, J., Sielaff-Frimpong, B., Glatzel, M., Matschke, J., Westphal, M., Iljin, K., Huhtala, H., Terracciano, L., Kallioniemi, A., Sauter, G., Müller, V., Witzel, I., Lamszus, K., Kemming, D. & Pantel, K., 16.03.2014, In: ONCOTARGET. 5, 10, p. 3076-3087Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Loss of 4q21.23-22.1 is a Prognostic Marker for Disease Free and Overall Survival in Non-Small Cell Lung Cancer
Uzunoglu, F. G., Dethlefsen, E., Hanssen, A., Wrage, M., Deutsch, L., Harms-Effenberger, K., Vashist, Y. K., Reeh, M., Sauter, G., Simon, R., Bockhorn, M., Pantel, K., Izbicki, J. R. & Wikman-Kocher, H., 01.01.2014, In: PLOS ONE. 9, 12, p. e113315Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
C-X-C motif receptor 2, endostatin and proteinase-activated receptor 1 polymorphisms as prognostic factors in NSCLC
Uzunoglu, F. G., Yavari, N., Bohn, B. A., Nentwich, M. F., Reeh, M., Pantel, K., Perez, D., Tsui, T. Y., Bockhorn, M., Mann, O., Izbicki, J. R., Wikman, H. & Vashist, Y. K., 01.07.2013, In: LUNG CANCER. 81, 1, p. 123-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases
Hohensee, I., Lamszus, K., Riethdorf, S., Meyer-Staeckling, S., Glatzel, M., Matschke, J., Witzel, I., Westphal, M., Brandt, B., Müller, V., Pantel, K. & Wikman, H., 01.07.2013, In: AM J PATHOL. 183, 1, p. 83-95 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
VEGFR-2, CXCR-2 and PAR-1 germline polymorphisms as predictors of survival in pancreatic carcinoma
Uzunoglu, F. G., Kolbe, J., Wikman, H., Güngör, C., Bohn, B. A., Nentwich, M. F., Reeh, M., König, A. M., Bockhorn, M., Kutup, A., Mann, O., Izbicki, J. R. & Vashist, Y. K., 01.05.2013, In: ANN ONCOL. 24, 5, p. 1282-90 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Accumulation of genomic alterations in 2p16, 9q33.1 and 19p13 in lung tumours of asbestos-exposed patients
Nymark, P., Aavikko, M., Mäkilä, J., Ruosaari, S., Hienonen-Kempas, T., Wikman, H., Salmenkivi, K., Pirinen, R., Karjalainen, A., Vanhala, E., Kuosma, E., Anttila, S. & Kettunen, E., 01.02.2013, In: MOL ONCOL. 7, 1, p. 29-40 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.
Lehtinen, L., Vainio, P., Wikman, H., Reemts, J., Hilvo, M., Issa, R., Pollari, S., Brandt, B., Oresic, M., Pantel, K., Kallioniemi, O. & Iljin, K., 2012, In: J PATHOL. 226, 4, p. 674-686 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating tumor-derived biomarkers in lung cancer.
Tänzer, A., Alix-Panabières, C., Wikman, H. & Pantel, K., 2012, In: J THORAC DIS. 4, 5, p. 448-449 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases.
Wikman, H., Sielaff-Frimpong, B., Kropidlowski, J., Witzel, I., Milde-Langosch, K., Sauter, G., Westphal, M., Lamszus, K. & Pantel, K., 2012, In: PLOS ONE. 7, 10, p. 47537 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Opposite roles of FOXA1 and NKX2-1 in lung cancer progression.
Deutsch, L., Wrage, M., Koops, S., Glatzel, M., Uzunoglu, F. G., Kutup, A., Hinsch, A., Sauter, G., Izbicki, J. R., Pantel, K. & Wikman, H., 2012, In: GENE CHROMOSOME CANC. 51, 6, p. 618-629 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevance of PTEN loss in brain metastasis formation in breast cancer patients.
Wikman, H., Lamszus, K., Detels, N., Uslar, L., Wrage, M., Benner, C., Hohensee, I., Ylstra, B., Eylmann, K., Zapatka, M., Sauter, G., Kemming, D., Glatzel, M., Müller, V., Westphal, M. & Pantel, K., 2012, In: BREAST CANCER RES. 14, 2, p. 49 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Vascular endothelial growth factor receptor 2 gene polymorphisms as predictors for tumor recurrence and overall survival in non-small-cell lung cancer.
Uzunoglu, F. G., Kaufmann, C., Wikman, H., Güngör, C., Bohn, B., Nentwich, M., Reeh, M., Pantel, K., Bockhorn, M., Kutup, A., Mann, O., Izbicki, J. R. & Vashist, Y., 2012, In: ANN SURG ONCOL. 19, 7, p. 2159-2168 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Biologic role of activated leukocyte cell adhesion molecule overexpression in breast cancer cell lines and clinical tumor tissue.
Hein, S., Müller, V., Köhler, N., Wikman, H., Krenkel, S., Streichert, T., Schweizer, M., Riethdorf, S., Assmann, V., Henningsen, M., Beck, K., Issa, R., Jänicke, F., Pantel, K. & Milde-Langosch, K., 2011, In: BREAST CANCER RES TR. 129, 2, p. 347-360 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
DNA copy number loss and allelic imbalance at 2p16 in lung cancer associated with asbestos exposure.
Kettunen, E., Aavikko, M., Nymark, P., Ruosaari, S., Wikman, H., Vanhala, E., Salmenkivi, K., Pirinen, R., Karjalainen, A., Kuosma, E. & Anttila, S., 2009, In: BRIT J CANCER. 100, 8, p. 1336-1342 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion.
Wrage, M., Ruosaari, S., Eijk, P. P., Kaifi, J., Hollmén, J., Yekebas, E. F., Izbicki, J. R., Brakenhoff, R. H., Streichert, T., Riethdorf, S., Glatzel, M., Ylstra, B., Pantel, K. & Wikman, H., 2009, In: CLIN CANCER RES. 15, 5, p. 1566-1574 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review.
Cote, M. L., Chen, W., Smith, D. W., Benhamou, S., Bouchardy, C., Butkiewicz, D., Fong, K. M., Gené, M., Hirvonen, A., Kiyohara, C., Larsen, J. E., Lin, P., Raaschou-Nielsen, O., Povey, A. C., Reszka, E., Risch, A., Schneider, J., Schwartz, A. G., Sorensen, M., Figueras, J. T., Tokudome, S., Pu, Y., Yang, P., Wenzlaff, A. S., Wikman, H. & Taioli, E., 2009, In: AM J EPIDEMIOL. 169, 7, p. 802-814 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular alterations at 9q33.1 and polyploidy in asbestos-related lung cancer.
Nymark, P., Kettunen, E., Aavikko, M., Ruosaari, S., Kuosma, E., Vanhala, E., Salmenkivi, K., Pirinen, R., Karjalainen, A., Knuutila, S., Wikman, H. & Anttila, S., 2009, In: CLIN CANCER RES. 15, 2, p. 468-475 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Cancer micrometastasis and tumour dormancy.
Wikman, H., Vessella, R. & Pantel, K., 2008, In: APMIS. 116, 7-8, p. 754-770 7-8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular and genetic changes in asbestos-related lung cancer.
Nymark, P., Wikman, H., Hienonen-Kempas, T. & Anttila, S., 2008, In: CANCER LETT. 265, 1, p. 1-15 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients.
Ruosaari, S., Hienonen-Kempas, T., Puustinen, A., Sarhadi, V. K., Hollmén, J., Knuutila, S., Saharinen, J., Wikman, H. & Anttila, S., 2008, In: BMC MED GENOMICS. 1, p. 55Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Review: Biological relevance of disseminated tumor cells in cancer patients.
Riethdorf, S., Wikman, H. & Pantel, K., 2008, In: INT J CANCER. 123, 9, p. 1991-2006 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer.
Wikman, H., Ruosaari, S., Nymark, P., Sarhadi, V. K., Saharinen, J., Vanhala, E., Karjalainen, A., Hollmén, J., Knuutila, S. & Anttila, S., 2007, In: ONCOGENE. 26, 32, p. 4730-4737 32.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review