Dr. ID: 58782

Harriet Wikman-Kocher

graph of relations

Publications

  1. 2024
  2. Frequency and Prognostic Value of Circulating Tumor Cells in Cancer of Unknown Primary

    Pouyiourou, M., Bochtler, T., Coith, C., Wikman, H., Kraft, B., Hielscher, T., Stenzinger, A., Riethdorf, S., Pantel, K. & Krämer, A., 04.01.2024, In: CLIN CHEM. 70, 1, p. 297-306 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. 2023
  4. RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer

    Prokakis, E., Jansari, S., Boshnakovska, A., Wiese, M., Kusch, K., Kramm, C., Dullin, C., Rehling, P., Glatzel, M., Pantel, K., Wikman, H., Johnsen, S. A., Gallwas, J. & Wegwitz, F., 28.09.2023, In: CELL DEATH DIS. 14, 9, p. 641

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Detection and Monitoring of Tumor-Derived Mutations in Circulating Tumor DNA Using the UltraSEEK Lung Panel on the MassARRAY System in Metastatic Non-Small Cell Lung Cancer Patients

    Leest, P. V. D., Janning, M., Rifaela, N., Azpurua, M. L. A., Kropidlowski, J., Loges, S., Lozano, N., Sartori, A., Irwin, D., Lamy, P-J., Hiltermann, T. J. N., Groen, H. J. M., Pantel, K., Kempen, L. C. V., Wikman, H. & Schuuring, E., 29.08.2023, In: INT J MOL SCI. 24, 17, 13390.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Label Efficient Classification in Liquid Biopsy Data by Self-supervision

    Husseini, H., Nielsen, M., Pantel, K., Wikman, H., Riethdorf, S. & Werner, R., 02.06.2023, Bildverarbeitung für die Medizin 2023: Proceedings, German Workshop on Medical Image Computing, Braunschweig, July 2-4, 2023. Deserno, T. M., Handels, H., Maier, A., Maier-Hein, K., Palm, C. & Tolxdorff, T. (eds.). 1 ed. Springer Vieweg, p. 261-266 6 p. (Informatik aktuell).

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  7. Comparative evaluation of PD-L1 expression in cytology imprints, circulating tumour cells and tumour tissue in non-small cell lung cancer patients

    Abdo, M., Belloum, Y., Heigener, D., Welker, L., von Weihe, S., Schmidt, M., Heuer-Olewinski, N., Watermann, I., Szewczyk, M., Kropidlowski, J., Pereira-Veiga, T., Elmas, H., Perner, S., Steurer, S., Wikman, H., Pantel, K. & Reck, M., 05.2023, In: MOL ONCOL. 17, 5, p. 737-746 10 p.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  8. The role of the desmosomal protein desmocollin 2 in tumour progression in triple negative breast cancer patients

    Reimer, F., Bryan, S., Legler, K., Karn, T., Eppenberger-Castori, S., Matschke, J., Pereira-Veiga, T., Wikman, H., Witzel, I., Müller, V., Schmalfeldt, B., Milde-Langosch, K., Schumacher, U., Stürken, C. & Oliveira-Ferrer, L., 16.03.2023, In: CANCER CELL INT. 23, 1, p. 47

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Peripheral and Portal Venous KRAS ctDNA Detection as Independent Prognostic Markers of Early Tumor Recurrence in Pancreatic Ductal Adenocarcinoma

    Nitschke, C., Markmann, B., Walter, P., Badbaran, A., Tölle, M., Kropidlowski, J., Belloum, Y., Goetz, M. R., Bardenhagen, J., Stern, L., Tintelnot, J., Schönlein, M., Sinn, M., van der Leest, P., Simon, R., Heumann, A., Izbicki, J. R., Pantel, K., Wikman, H. & Uzunoglu, F. G., 01.03.2023, In: CLIN CHEM. 69, 3, p. 295-307 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. 2022
  11. Circulating Cancer Associated Macrophage-like Cells as a Potential New Prognostic Marker in Pancreatic Ductal Adenocarcinoma

    Nitschke, C., Markmann, B., Konczalla, L., Kropidlowski, J., Pereira-Veiga, T., Scognamiglio, P., Schönrock, M., Sinn, M., Tölle, M., Izbicki, J., Pantel, K., Uzunoglu, F. G. & Wikman, H., 17.11.2022, In: BIOMEDICINES. 10, 11, 2955.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Circulating tumor cells and extracellular vesicles as liquid biopsy markers in neuro-oncology: prospects and limitations

    Westphal, M., Pantel, K., Ricklefs, F. L., Maire, C., Riethdorf, S., Mohme, M., Wikman, H. & Lamszus, K., 11.2022, In: NEURO-ONCOL ADV. 4, Suppl 2, p. ii45-ii52

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Clinical applications and utility of cell-free DNA-based liquid biopsy analyses in cervical cancer and its precursor lesions

    Herbst, J., Pantel, K., Effenberger, K. & Wikman, H., 11.2022, In: BRIT J CANCER. 127, 8, p. 1403-1410 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  14. Clinical determinants impacting overall survival of patients with operable brain metastases from non-small cell lung cancer

    Piffko, A., Asey, B., Dührsen, L., Ristow, I., Salamon, J., Wikman, H., Maire, C. L., Lamszus, K., Westphal, M., Sauvigny, T. & Mohme, M., 20.10.2022, In: FRONT ONCOL. 12, 951805.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Characterization of RARRES1 Expression on Circulating Tumor Cells as Unfavorable Prognostic Marker in Resected Pancreatic Ductal Adenocarcinoma Patients

    Nitschke, C., Markmann, B., Tölle, M., Kropidlowski, J., Belloum, Y., Goetz, M. R., Schlüter, H., Kwiatkowski, M., Sinn, M., Izbicki, J., Pantel, K., Güngör, C., Uzunoglu, F. G. & Wikman, H., 10.09.2022, In: CANCERS. 14, 18, 4405.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Circulating tumor cell-blood cell crosstalk: Biology and clinical relevance

    Pereira-Veiga, T., Schneegans, S., Pantel, K. & Wikman, H., 30.08.2022, In: CELL REP. 40, 9, 111298.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  17. Combined Liquid Biopsy Methylation Analysis of CADM1 and MAL in Cervical Cancer Patients

    Leffers, M., Herbst, J., Kropidlowski, J., Prieske, K., Bohnen, A. L., Peine, S., Jaeger, A., Prieske, K., Goy, Y., Schmalfeldt, B., Pantel, K., Wölber, L., Effenberger, K. & Wikman, H., 16.08.2022, In: CANCERS. 14, 16, 3954.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Expression Patterns and Corepressor Function of Retinoic Acid-induced 2 in Prostate Cancer

    Besler, K., Węglarz, A., Keller, L., von Amsberg, G., Bednarz-Knoll, N., Offermann, A., Stoupiec, S., Eltze, E., Semjonow, A., Boettcher, L., Schneegans, S., Perner, S., Hauch, S., Todenhöfer, T., Peine, S., Pantel, K., Wikman, H. & Werner, S., 03.07.2022, In: CLIN CHEM. 68, 7, p. 973-983 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism

    Monteiro, C., Miarka, L., Perea-García, M., Priego, N., García-Gómez, P., Álvaro-Espinosa, L., de Pablos-Aragoneses, A., Yebra, N., Retana, D., Baena, P., Fustero-Torre, C., Graña-Castro, O., Troulé, K., Caleiras, E., Tezanos, P., Muela, P., Cintado, E., Trejo, J. L., Sepúlveda, J. M., González-León, P., Jiménez-Roldán, L., Moreno, L. M., Esteban, O., Pérez-Núñez, Á., Hernández-Lain, A., Mazarico Gallego, J., Ferrer, I., Suárez, R., Garrido-Martín, E. M., Paz-Ares, L., Dalmasso, C., Cohen-Jonathan Moyal, E., Siegfried, A., Hegarty, A., Keelan, S., Varešlija, D., Young, L. S., Mohme, M., Goy, Y., Wikman, H., Fernández-Alén, J., Blasco, G., Alcázar, L., Cabañuz, C., Grivennikov, S. I., Ianus, A., Shemesh, N., Faria, C. C., Lee, R., Lorigan, P., Le Rhun, E., Weller, M., Soffietti, R., Bertero, L., Ricardi, U., Bosch-Barrera, J., Sais, E., Teixidor, E., Hernández-Martínez, A., Calvo, A., Aristu, J., Martin, S. M., Gonzalez, A., Adler, O., Erez, N. & Valiente, M., 04.2022, In: NAT MED. 28, 4, p. 752-765 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Decellularized In Vitro Capillaries for Studies of Metastatic Tendency and Selection of Treatment

    Huttala, O., Loreth, D., Staff, S., Tanner, M., Wikman, H. & Ylikomi, T., 26.01.2022, In: BIOMEDICINES. 10, 2, 271.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Spine Metastases in Immunocompromised Mice after Intracardiac Injection of MDA-MB-231-SCP2 Breast Cancer Cells

    Brylka, L., Jähn-Rickert, K., Baranowsky, A., Neven, M., Horn, M., Yorgan, T., Wikman, H., Werner, S., Lübke, A., Amling, M., Busse, B., Pantel, K. & Schinke, T., 22.01.2022, In: CANCERS. 14, 3, 556.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. 2021
  23. Decreased PRC2 activity supports the survival of basal-like breast cancer cells to cytotoxic treatments

    Mieczkowska, I. K., Pantelaiou-Prokaki, G., Prokakis, E., Schmidt, G. E., Müller-Kirschbaum, L. C., Werner, M., Sen, M., Velychko, T., Jannasch, K., Dullin, C., Napp, J., Pantel, K., Wikman, H., Wiese, M., Kramm, C. M., Alves, F. & Wegwitz, F., 29.11.2021, In: CELL DEATH DIS. 12, 12, 1118.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. P02.01 A strategy to personalize the use of radiation in patients with brain metastasis based on S100A9-mediated resistance

    Miarka, L., Monteiro, C., Dalmasso, C., Yebra, N., Fustero-Torre, C., Hegarty, A., Keelan, S., Goy, Y., Mohme, M., Caleiras, E., Vareslija, D., Young, L., Soffietti, R., Fernández-Alén, J., Blasco, G., Alcázar, L., Sepúlveda, J., Pérez, A., Lain, A., Siegfried, A., Wikman, H., Cohen-Jonathan Moyal, E. & Valiente, M., 01.09.2021, In: NEURO-ONCOLOGY. 23, Supplement_2, p. ii17-ii17

    Research output: SCORING: Contribution to journalConference abstract in journalResearchpeer-review

  25. Emerging Insights into Keratin 16 Expression during Metastatic Progression of Breast Cancer

    Elazezy, M., Schwentesius, S., Stegat, L., Wikman, H., Werner, S., Mansour, W. Y., Failla, A. V., Peine, S., Müller, V., Thiery, J. P., Ebrahimi Warkiani, M., Pantel, K. & Joosse, S. A., 31.07.2021, In: CANCERS. 13, 15, 3869.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis

    Loreth, D., Schuette, M., Zinke, J., Mohme, M., Piffko, A., Schneegans, S., Stadler, J., Janning, M., Loges, S., Joosse, S. A., Lamszus, K., Westphal, M., Müller, V., Glatzel, M., Matschke, J., Gebhardt, C., Schneider, S. W., Belczacka, I., Volkmer, B., Greinert, R., Yaspo, M-L., Harter, P. N., Pantel, K. & Wikman, H., 29.06.2021, In: INT J MOL SCI. 22, 13, 6993.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Proficiency Testing to Assess Technical Performance for CTC-Processing and Detection Methods in CANCER-ID

    Neves, R. P. L., Ammerlaan, W., Andree, K. C., Bender, S., Cayrefourcq, L., Driemel, C., Koch, C., Luetke-Eversloh, M. V., Oulhen, M., Rossi, E., Alix-Panabières, C., Betsou, F., Farace, F., Riethdorf, S., Schlange, T., Wikman, H., Zamarchi, R., Pantel, K., Terstappen, L. W. M. M., Stoecklein, N. H. & CANCER-ID Consortium, 31.03.2021, In: CLIN CHEM. 67, 4, p. 631-641 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions

    Pantano, F., Croset, M., Driouch, K., Bednarz-Knoll, N., Iuliani, M., Ribelli, G., Bonnelye, E., Wikman, H., Geraci, S., Bonin, F., Simonetti, S., Vincenzi, B., Hong, S. S., Sousa, S., Pantel, K., Tonini, G., Santini, D. & Clézardin, P., 02.2021, In: ONCOGENE. 40, 7, p. 1284-1299 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond

    Keller, L., Belloum, Y., Wikman, H. & Pantel, K., 01.2021, In: BRIT J CANCER. 124, 2, p. 345-358 14 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  30. 2020
  31. Discovery of Targetable Genetic Alterations in NSCLC Patients with Different Metastatic Patterns Using a MassARRAY-Based Circulating Tumor DNA Assay

    Belloum, Y., Janning, M., Mohme, M., Simon, R., Kropidlowski, J., Sartori, A., Irwin, D., Westphal, M., Lamszus, K., Loges, S., Riethdorf, S., Pantel, K. & Wikman, H., 22.10.2020, In: CELLS-BASEL. 9, 11, E2337.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization against PARP1 Inhibition in a Replication-Dependent Manner

    Rieckhoff, J., Meyer, F., Classen, S., Zielinski, A., Riepen, B., Wikman, H., Petersen, C., Rothkamm, K., Borgmann, K. & Parplys, A. C., 29.09.2020, In: CANCERS. 12, 10

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. ALCAM contributes to brain metastasis formation in non-small-cell lung cancer through interaction with the vascular endothelium

    Münsterberg, J., Loreth, D., Brylka, L., Werner, S., Karbanova, J., Gandrass, M., Schneegans, S., Besler, K., Hamester, F., Robador, J. R., Bauer, A. T., Werner Schneider, S., Wrage, M., Lamszus, K., Matschke, J., Vashist, Y., Uzunoglu, G., Steurer, S., Horst, A. K., Oliveira-Ferrer, L., Glatzel, M., Schinke, T., Corbeil, D., Pantel, K., Maire, C. & Wikman, H., 07.07.2020, In: NEURO-ONCOLOGY. 22, 7, p. 955-966 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Pre-analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients

    Schneegans, S., Lück, L., Besler, K., Bluhm, L., Stadler, J-C., Staub, J., Greinert, R., Volkmer, B., Kubista, M., Gebhardt, C., Sartori, A., Irwin, D., Serkkola, E., Af Hällström, T., Lianidou, E., Sprenger-Haussels, M., Hussong, M., Mohr, P., Schneider, S. W., Shaffer, J., Pantel, K. & Wikman, H., 05.2020, In: MOL ONCOL. 14, 5, p. 1001-1015 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer

    Meyer, F., Becker, S., Classen, S., Parplys, A. C., Mansour, W. Y., Riepen, B., Timm, S., Ruebe, C., Jasin, M., Wikman, H., Petersen, C., Rothkamm, K. & Borgmann, K., 17.01.2020, In: CELLS-BASEL. 9, 1

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows

    Lampignano, R., Neumann, M. H. D., Weber, S., Kloten, V., Herdean, A., Voss, T., Groelz, D., Babayan, A., Tibbesma, M., Schlumpberger, M., Chemi, F., Rothwell, D. G., Wikman, H., Galizzi, J-P., Bergheim, I. R., Russnes, H., Mussolin, B., Bonin, S., Voigt, C., Musa, H., Pinzani, P., Lianidou, E., Brady, G., Speicher, M. R., Pantel, K., Betsou, F., Schuuring, E., Kubista, M., Ammerlaan, W., Sprenger-Haussels, M., Schlange, T., Heitzer, E. & Innovative Medicines Initiative CANCER-ID Consortium, 01.01.2020, In: CLIN CHEM. 66, 1, p. 149-160 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. 2019
  38. Clonality of circulating tumor cells in breast cancer brain metastasis patients

    Riebensahm, C., Joosse, S. A., Mohme, M., Hanssen, A., Matschke, J., Goy, Y., Witzel, I., Lamszus, K., Kropidlowski, J., Petersen, C., Kolb-Kokocinski, A., Sauer, S., Borgmann, K., Glatzel, M., Müller, V., Westphal, M., Riethdorf, S., Pantel, K. & Wikman, H., 03.09.2019, In: BREAST CANCER RES. 21, 1, p. 101

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. EPAC-lung: pooled analysis of circulating tumour cells in advanced non-small cell lung cancer

    Lindsay, C. R., Blackhall, F. H., Carmel, A., Fernandez-Gutierrez, F., Gazzaniga, P., Groen, H. J. M., Hiltermann, T. J. N., Krebs, M. G., Loges, S., López-López, R., Muinelo-Romay, L., Pantel, K., Priest, L., Riethdorf, S., Rossi, E., Terstappen, L., Wikman, H., Soria, J-C., Farace, F., Renehan, A., Dive, C., Besse, B. & Michiels, S., 08.2019, In: EUR J CANCER. 117, p. 60-68 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors

    Janning, M., Kobus, F., Babayan, A., Wikman, H., Velthaus, J-L., Bergmann, S., Schatz, S., Falk, M., Berger, L-A., Böttcher, L-M., Päsler, S., Gorges, T. M., O'Flaherty, L., Hille, C., Joosse, S. A., Simon, R., Tiemann, M., Bokemeyer, C., Reck, M., Riethdorf, S., Pantel, K. & Loges, S., 17.06.2019, In: CANCERS. 11, 6

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. EGFR and HER3 expression in circulating tumor cells and tumor tissue from non-small cell lung cancer patients

    Scharpenseel, H., Hanssen, A., Loges, S., Mohme, M., Bernreuther, C., Peine, S., Lamszus, K., Goy, Y., Petersen, C., Westphal, M., Glatzel, M., Riethdorf, S., Pantel, K. & Wikman, H., 15.05.2019, In: SCI REP-UK. 9, 1, p. 7406

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. 2018
  43. Frequency of Circulating Tumor Cells (CTC) in Patients with Brain Metastases: Implications as a Risk Assessment Marker in Oligo-Metastatic Disease

    Hanssen, A., Riebensahm, C., Mohme, M., Joosse, S. A., Velthaus, J-L., Berger, L. A., Bernreuther, C., Glatzel, M., Loges, S., Lamszus, K., Westphal, M., Riethdorf, S., Pantel, K. & Wikman, H., 19.12.2018, In: CANCERS. 10, 12, p. E527

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Identification of a High-Level MET Amplification in CTCs and cfTNA of an ALK-Positive NSCLC Patient Developing Evasive Resistance to Crizotinib

    Berger, L-A., Janning, M., Velthaus, J-L., Ben-Batalla, I., Schatz, S., Falk, M., Iglauer, P., Simon, R., Cao, R., Forcato, C., Manaresi, N., Bramlett, K., Buson, G., Hanssen, A., Tiemann, M., Sauter, G., Bokemeyer, C., Riethdorf, S., Reck, M., Pantel, K., Wikman, H. & Loges, S., 12.2018, In: J THORAC ONCOL. 13, 12, p. e243-e246

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Clinical relevance of cytoskeleton associated proteins for ovarian cancer

    Schiewek, J., Schumacher, U., Lange, T., Joosse, S. A., Wikman, H., Pantel, K., Mikhaylova, M., Kneussel, M., Linder, S., Schmalfeldt, B., Oliveira-Ferrer, L. & Windhorst, S., 11.2018, In: J CANCER RES CLIN. 144, 11, p. 2195-2205 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Chromosomal Aberrations Associated with Sequential Steps of the Metastatic Cascade in Colorectal Cancer Patients

    Joosse, S. A., Souche, F-R., Babayan, A., Gasch, C., Kerkhoven, R. M., Ramos, J., Fabre, J-M., Riethdorf, S., König, A., Wikman, H., Alix-Panabières, C. & Pantel, K., 10.2018, In: CLIN CHEM. 64, 10, p. 1505-1512 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Stromal Caveolin-1 and Caveolin-2 Expression in Primary Tumors and Lymph Node Metastases

    Gerstenberger, W., Wrage, M., Kettunen, E., Pantel, K., Anttila, S., Steurer, S. & Wikman, H., 2018, In: ANAL CELL PATHOL. 2018, p. 8651790

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. 2017
  49. Strong fascin expression promotes metastasis independent of its F-actin bundling activity

    Heinz, L. S., Muhs, S., Schiewek, J., Grüb, S., Nalaskowski, M., Lin, Y-N., Wikman, H., Oliveira-Ferrer, L., Lange, T., Wellbrock, J., Konietzny, A., Mikhaylova, M. & Windhorst, S., 15.12.2017, In: ONCOTARGET. 8, 66, p. 110077-110091 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells

    Babayan, A., Alawi, M., Gormley, M., Müller, V., Wikman, H., McMullin, R. P., Smirnov, D. A., Li, W., Geffken, M., Pantel, K. & Joosse, S. A., 22.08.2017, In: ONCOTARGET. 8, 34, p. 56066-56080 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases

    Mohme, M., Riethdorf, S., Dreimann, M., Werner, S., Maire, C. L., Joosse, S. A., Bludau, F., Mueller, V., Neves, R. P. L., Stoecklein, N. H., Lamszus, K., Westphal, M., Pantel, K., Wikman, H. & Eicker, S. O., 03.08.2017, In: SCI REP-UK. 7, 1, p. 7196

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. Biology and clinical significance of circulating tumor cell subpopulations in lung cancer

    O'Flaherty, L., Wikman, H. & Pantel, K., 08.2017, In: TRANSL LUNG CANCER R. 6, 4, p. 431-443 13 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  53. Nanoplatforms for Circulating Tumor Cell Detection in Lung Cancer

    Wikman, H. & Pantel, K., 08.2017, In: CLIN CHEM. 63, 8, p. 1318-1320 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  54. PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cells

    Lehtinen, L., Vainio, P., Wikman, H., Huhtala, H., Mueller, V., Kallioniemi, A., Pantel, K., Kronqvist, P., Kallioniemi, O., Carpèn, O. & Iljin, K., 04.2017, In: J PATHOL CLIN RES. 3, 2, p. 123-138 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  55. Role of HYAL1 expression in primary breast cancer in the formation of brain metastases

    Witzel, I., Marx, A. K., Müller, V., Wikman, H., Matschke, J., Schumacher, U., Stürken, C., Prehm, P., Laakmann, E., Schmalfeldt, B., Milde-Langosch, K. & Oliveira-Ferrer, L., 04.2017, In: BREAST CANCER RES TR. 162, 3, p. 427-438 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  56. PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression

    Hohensee, I., Chuang, H-N., Grottke, A., Werner, S., Schulte, A., Horn, S., Lamszus, K., Bartkowiak, K., Witzel, I., Westphal, M., Matschke, J., Glatzel, M., Jücker, M., Pukrop, T., Pantel, K. & Wikman, H., 01.2017, In: ONCOTARGET. 8, 4, p. 6155-6168

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  57. 2016
  58. Enumeration and molecular characterization of tumor cells in lung cancer patients using a novel in vivo device for capturing circulating tumor cells

    Gorges, T. M., Penkalla, N., Schalk, T., Joosse, S., Riethdorf, S., Tucholski, J., Lucke, K., Wikman, H., Jackson, S. M., Brychter, N., von Ahsen, O., Schumann, C., Krahn, T. & Pantel, K., 01.05.2016, In: CLIN CANCER RES. 22, 9, p. 2197-206

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  59. Potential Involvement of Jagged1 in Metastatic Progression of Human Breast Carcinomas

    Bednarz-Knoll, N., Efstathiou, A., Gotzhein, F., Wikman, H., Mueller, V., Kang, Y. & Pantel, K., 02.2016, In: CLIN CHEM. 62, 2, p. 378-386

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  60. A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells

    Hvichia, G. E., Parveen, Z., Wagner, C., Janning, M., Quidde, J., Stein, A., Müller, V., Loges, S., Neves, R. P. L., Stoecklein, N. H., Wikman, H., Riethdorf, S., Pantel, K. & Gorges, T. M., 20.01.2016, In: INT J CANCER. 138, 12, p. 2894-904

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  61. Breast cancer brain metastases:biology and new clinical perspectives

    Witzel, I., Oliveira-Ferrer, L., Pantel, K., Müller, V. & Wikman, H., 19.01.2016, In: BREAST CANCER RES. 18, 1, p. 8

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  62. Characterization of different CTC subpopulations in non-small cell lung cancer

    Hanssen, A., Wagner, J., Gorges, T. M., Tänzer, A., Uzunoglu, F. G., Driemel, C., Stoecklein, N. H., Knoefel, W. T., Angenendt, S., Hauch, S., Atanackovic, D., Loges, S., Riethdorf, S., Pantel, K. & Wikman, H., 2016, In: SCI REP-UK. 6, p. 28010

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  63. 2015
  64. Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response

    Bartkowiak, K., Kwiatkowski, M., Buck, F., Gorges, T. M., Nilse, L., Assmann, V., Andreas, A., Müller, V., Wikman, H., Riethdorf, S., Schlüter, H. & Pantel, K., 15.12.2015, In: CANCER RES. 75, 24, p. 5367-77 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  65. Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases

    Harter, P. N., Bernatz, S., Scholz, A., Zeiner, P. S., Zinke, J., Kiyose, M., Blasel, S., Beschorner, R., Senft, C., Bender, B., Ronellenfitsch, M. W., Wikman-Kocher, H., Glatzel, M., Meinhardt, M., Juratli, T. A., Steinbach, J. P., Plate, K. H., Wischhusen, J., Weide, B. & Mittelbronn, M., 12.2015, In: ONCOTARGET. 6, 38, p. 40836-40849

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  66. Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression

    Bednarz-Knoll, N., Nastały, P., Żaczek, A., Stoupiec, M., Riethdorf, S., Wikman-Kocher, H., Müller, V., Skokowski, J., Szade, J., Sejda, A., Wełnicka-Jaśkiewicz, M. & Pantel, K., 29.09.2015, In: ONCOTARGET. 6, 29, p. 26789-803 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  67. Detection of Circulating Tumor Cells in Non-Small Cell Lung Cancer

    Hanssen, A., Loges, S., Pantel, K. & Wikman-Kocher, H., 22.09.2015, In: FRONT ONCOL. 5, p. Art. 207

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  68. Relevance of βGal-βGalNAc-containing glycans and the enzymes involved in their synthesis for invasion and survival in breast cancer patients

    Milde-Langosch, K., Schütze, D., Oliveira-Ferrer, L., Wikman-Kocher, H., Müller, V., Lebok, P., Pantel, K., Schröder, C., Witzel, I. & Schumacher, U., 06.2015, In: BREAST CANCER RES TR. 151, 3, p. 515-28 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  69. Identification of HERC5 and its potential role in NSCLC progression

    Wrage, M., Hagmann, W., Kemming, D., Uzunoglu, F. G., Riethdorf, S., Harms-Effenberger, K., Westphal, M., Lamszus, K., Kim, S-Z., Becker, N., Izbicki, J. R., Sandoval, J., Esteller, M., Pantel, K., Risch, A. & Wikman-Kocher, H., 15.05.2015, In: INT J CANCER. 136, 10, p. 2264-72

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  70. Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells

    Werner, S., Stamm, H., Pandjaitan, M., Kemming, D., Brors, B., Pantel, K. & Wikman, H., 2015, In: BMC CANCER. 15, 1, p. 896

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  71. Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic acid induced 2

    Werner, S., Brors, B., Eick, J., Marques, E., Pogenberg, V., Parret, A., Kemming, D., Wood, A. W., Edgren, H., Neubauer, H., Streichert, T., Riethdorf, S., Bedi, U., Baccelli, I., Jücker, M., Eils, R., Fehm, T., Trumpp, A., Johnsen, S. A., Klefstrom, J., Wilmanns, M., Müller, V., Pantel, K. & Wikman-Kocher, H., 2015, In: CANCER DISCOV. 5, 5, p. 506-19

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  72. 2014
  73. Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients

    Eichelser, C., Stückrath, I., Müller, V., Milde-Langosch, K., Wikman-Kocher, H., Pantel, K. & Schwarzenbach, H., 30.10.2014, In: ONCOTARGET. 5, 20, p. 9650-63 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  74. PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

    LeBleu, V. S., O'Connell, J. T., Gonzalez Herrera, K. N., Wikman-Kocher, H., Pantel, K., Haigis, M. C., de Carvalho, F. M., Damascena, A., Domingos Chinen, L. T., Rocha, R. M., Asara, J. M. & Kalluri, R., 01.10.2014, In: NAT CELL BIOL. 16, 10, p. 992-1003

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  75. Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients

    Wikman-Kocher, H., Westphal, L., Schmid, F., Pollari, S., Kropidlowski, J., Sielaff-Frimpong, B., Glatzel, M., Matschke, J., Westphal, M., Iljin, K., Huhtala, H., Terracciano, L., Kallioniemi, A., Sauter, G., Müller, V., Witzel, I., Lamszus, K., Kemming, D. & Pantel, K., 16.03.2014, In: ONCOTARGET. 5, 10, p. 3076-3087

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  76. Loss of 4q21.23-22.1 is a Prognostic Marker for Disease Free and Overall Survival in Non-Small Cell Lung Cancer

    Uzunoglu, F. G., Dethlefsen, E., Hanssen, A., Wrage, M., Deutsch, L., Harms-Effenberger, K., Vashist, Y. K., Reeh, M., Sauter, G., Simon, R., Bockhorn, M., Pantel, K., Izbicki, J. R. & Wikman-Kocher, H., 01.01.2014, In: PLOS ONE. 9, 12, p. e113315

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  77. 2013
  78. C-X-C motif receptor 2, endostatin and proteinase-activated receptor 1 polymorphisms as prognostic factors in NSCLC

    Uzunoglu, F. G., Yavari, N., Bohn, B. A., Nentwich, M. F., Reeh, M., Pantel, K., Perez, D., Tsui, T. Y., Bockhorn, M., Mann, O., Izbicki, J. R., Wikman, H. & Vashist, Y. K., 01.07.2013, In: LUNG CANCER. 81, 1, p. 123-9 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  79. Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases

    Hohensee, I., Lamszus, K., Riethdorf, S., Meyer-Staeckling, S., Glatzel, M., Matschke, J., Witzel, I., Westphal, M., Brandt, B., Müller, V., Pantel, K. & Wikman, H., 01.07.2013, In: AM J PATHOL. 183, 1, p. 83-95 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  80. VEGFR-2, CXCR-2 and PAR-1 germline polymorphisms as predictors of survival in pancreatic carcinoma

    Uzunoglu, F. G., Kolbe, J., Wikman, H., Güngör, C., Bohn, B. A., Nentwich, M. F., Reeh, M., König, A. M., Bockhorn, M., Kutup, A., Mann, O., Izbicki, J. R. & Vashist, Y. K., 01.05.2013, In: ANN ONCOL. 24, 5, p. 1282-90 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  81. Accumulation of genomic alterations in 2p16, 9q33.1 and 19p13 in lung tumours of asbestos-exposed patients

    Nymark, P., Aavikko, M., Mäkilä, J., Ruosaari, S., Hienonen-Kempas, T., Wikman, H., Salmenkivi, K., Pirinen, R., Karjalainen, A., Vanhala, E., Kuosma, E., Anttila, S. & Kettunen, E., 01.02.2013, In: MOL ONCOL. 7, 1, p. 29-40 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  82. 2012
  83. 15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.

    Lehtinen, L., Vainio, P., Wikman, H., Reemts, J., Hilvo, M., Issa, R., Pollari, S., Brandt, B., Oresic, M., Pantel, K., Kallioniemi, O. & Iljin, K., 2012, In: J PATHOL. 226, 4, p. 674-686 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  84. Circulating tumor-derived biomarkers in lung cancer.

    Tänzer, A., Alix-Panabières, C., Wikman, H. & Pantel, K., 2012, In: J THORAC DIS. 4, 5, p. 448-449 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  85. Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases.

    Wikman, H., Sielaff-Frimpong, B., Kropidlowski, J., Witzel, I., Milde-Langosch, K., Sauter, G., Westphal, M., Lamszus, K. & Pantel, K., 2012, In: PLOS ONE. 7, 10, p. 47537 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  86. Opposite roles of FOXA1 and NKX2-1 in lung cancer progression.

    Deutsch, L., Wrage, M., Koops, S., Glatzel, M., Uzunoglu, F. G., Kutup, A., Hinsch, A., Sauter, G., Izbicki, J. R., Pantel, K. & Wikman, H., 2012, In: GENE CHROMOSOME CANC. 51, 6, p. 618-629 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  87. Relevance of PTEN loss in brain metastasis formation in breast cancer patients.

    Wikman, H., Lamszus, K., Detels, N., Uslar, L., Wrage, M., Benner, C., Hohensee, I., Ylstra, B., Eylmann, K., Zapatka, M., Sauter, G., Kemming, D., Glatzel, M., Müller, V., Westphal, M. & Pantel, K., 2012, In: BREAST CANCER RES. 14, 2, p. 49 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  88. Vascular endothelial growth factor receptor 2 gene polymorphisms as predictors for tumor recurrence and overall survival in non-small-cell lung cancer.

    Uzunoglu, F. G., Kaufmann, C., Wikman, H., Güngör, C., Bohn, B., Nentwich, M., Reeh, M., Pantel, K., Bockhorn, M., Kutup, A., Mann, O., Izbicki, J. R. & Vashist, Y., 2012, In: ANN SURG ONCOL. 19, 7, p. 2159-2168 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  89. 2011
  90. Biologic role of activated leukocyte cell adhesion molecule overexpression in breast cancer cell lines and clinical tumor tissue.

    Hein, S., Müller, V., Köhler, N., Wikman, H., Krenkel, S., Streichert, T., Schweizer, M., Riethdorf, S., Assmann, V., Henningsen, M., Beck, K., Issa, R., Jänicke, F., Pantel, K. & Milde-Langosch, K., 2011, In: BREAST CANCER RES TR. 129, 2, p. 347-360 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  91. 2009
  92. DNA copy number loss and allelic imbalance at 2p16 in lung cancer associated with asbestos exposure.

    Kettunen, E., Aavikko, M., Nymark, P., Ruosaari, S., Wikman, H., Vanhala, E., Salmenkivi, K., Pirinen, R., Karjalainen, A., Kuosma, E. & Anttila, S., 2009, In: BRIT J CANCER. 100, 8, p. 1336-1342 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  93. Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion.

    Wrage, M., Ruosaari, S., Eijk, P. P., Kaifi, J., Hollmén, J., Yekebas, E. F., Izbicki, J. R., Brakenhoff, R. H., Streichert, T., Riethdorf, S., Glatzel, M., Ylstra, B., Pantel, K. & Wikman, H., 2009, In: CLIN CANCER RES. 15, 5, p. 1566-1574 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  94. Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review.

    Cote, M. L., Chen, W., Smith, D. W., Benhamou, S., Bouchardy, C., Butkiewicz, D., Fong, K. M., Gené, M., Hirvonen, A., Kiyohara, C., Larsen, J. E., Lin, P., Raaschou-Nielsen, O., Povey, A. C., Reszka, E., Risch, A., Schneider, J., Schwartz, A. G., Sorensen, M., Figueras, J. T., Tokudome, S., Pu, Y., Yang, P., Wenzlaff, A. S., Wikman, H. & Taioli, E., 2009, In: AM J EPIDEMIOL. 169, 7, p. 802-814 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  95. Molecular alterations at 9q33.1 and polyploidy in asbestos-related lung cancer.

    Nymark, P., Kettunen, E., Aavikko, M., Ruosaari, S., Kuosma, E., Vanhala, E., Salmenkivi, K., Pirinen, R., Karjalainen, A., Knuutila, S., Wikman, H. & Anttila, S., 2009, In: CLIN CANCER RES. 15, 2, p. 468-475 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  96. 2008
  97. Cancer micrometastasis and tumour dormancy.

    Wikman, H., Vessella, R. & Pantel, K., 2008, In: APMIS. 116, 7-8, p. 754-770 7-8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  98. Molecular and genetic changes in asbestos-related lung cancer.

    Nymark, P., Wikman, H., Hienonen-Kempas, T. & Anttila, S., 2008, In: CANCER LETT. 265, 1, p. 1-15 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  99. Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients.

    Ruosaari, S., Hienonen-Kempas, T., Puustinen, A., Sarhadi, V. K., Hollmén, J., Knuutila, S., Saharinen, J., Wikman, H. & Anttila, S., 2008, In: BMC MED GENOMICS. 1, p. 55

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  100. Review: Biological relevance of disseminated tumor cells in cancer patients.

    Riethdorf, S., Wikman, H. & Pantel, K., 2008, In: INT J CANCER. 123, 9, p. 1991-2006 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  101. 2007
  102. Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer.

    Wikman, H., Ruosaari, S., Nymark, P., Sarhadi, V. K., Saharinen, J., Vanhala, E., Karjalainen, A., Hollmén, J., Knuutila, S. & Anttila, S., 2007, In: ONCOGENE. 26, 32, p. 4730-4737 32.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review