Prof.Dr.rer.nat ID: 73722

Thorsten Schinke

graph of relations

Publications

  1. 2016
  2. No obvious phenotypic abnormalities in mice lacking the Pate4 gene

    Heckt, T., Keller, J., Reusch, R., Hartmann, K., Krasemann, S., Hermans-Borgmeyer, I., Amling, M. & Schinke, T., 22.01.2016, In: BIOCHEM BIOPH RES CO. 469, 4, p. 1069-1074

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Can we induce osteoporosis in animals comparable to the human situation?

    Oheim, R., Schinke, T., Amling, M. & Pogoda, P., 01.2016, In: INJURY. 47 Suppl 1, p. S3-9

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Die endokrine Funktion der Osteozyten

    Yorgan, T. & Schinke, T., 2016, In: OSTEOLOGIE. 25, 2, p. 62-68 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Inhibition of Midkine Augments Osteoporotic Fracture Healing

    Haffner-Luntzer, M., Kemmler, J., Heidler, V., Prystaz, K., Schinke, T., Amling, M., Kovtun, A., Rapp, A. E., Ignatius, A. & Liedert, A., 2016, In: PLOS ONE. 11, 7, p. e0159278

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. 2015
  7. Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I

    Kühn, S. C., Koehne, T., Cornils, K., Markmann, S., Riedel, C., Pestka, J. M., Schweizer, M., Baldauf, C., Yorgan, T. A., Krause, M., Keller, J., Neven, M., Breyer, S., Stücker, R., Muschol, N., Busse, B., Braulke, T., Fehse, B., Amling, M. & Schinke, T., 15.12.2015, In: HUM MOL GENET. 24, 24, p. 7075-7086

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells

    Jeschke, A., Catala-Lehnen, P., Sieber, S., Bickert, T., Schweizer, M., Koehne, T., Wintges, K., Marshall, R. P., Mautner, A., Duchstein, L., Otto, B., Horst, A. K., Amling, M., Kreienkamp, H-J. & Schinke, T., 15.10.2015, In: J IMMUNOL. 195, 8, p. 3675-84 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. The Anti-Osteoanabolic Function of Sclerostin is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5

    Yorgan, T. A., Peters, S., Jeschke, A., Benisch, P., Jakob, F., Amling, M. & Schinke, T., 07.2015, In: J BONE MINER RES. 30, 7, p. 1175-1183

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Calcium gluconate supplementation is effective to balance calcium homeostasis in patients with gastrectomy

    Krause, M., Keller, J., Beil, B., van Driel, I., Zustin, J., Barvencik, F., Schinke, T. & Amling, M., 03.2015, In: OSTEOPOROSIS INT. 26, 3, p. 987-95 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. The impact of low-magnitude high-frequency vibration on fracture healing is profoundly influenced by the oestrogen status in mice

    Wehrle, E., Liedert, A., Heilmann, A., Wehner, T., Bindl, R., Fischer, L., Haffner-Luntzer, M., Jakob, F., Schinke, T., Amling, M. & Ignatius, A., 01.2015, In: DIS MODEL MECH. 8, 1, p. 93-104 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Deficiency of Thrombospondin-4 in Mice Does Not Affect Skeletal Growth or Bone Mass Acquisition, but Causes a Transient Reduction of Articular Cartilage Thickness

    Jeschke, A., Bonitz, M., Simon, M., Peters, S., Baum, W., Schett, G., Ruether, W., Niemeier, A., Schinke, T. & Amling, M., 2015, In: PLOS ONE. 10, 12, p. e0144272

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. The Protein Tyrosine Phosphatase Rptpζ Suppresses Osteosarcoma Development in Trp53-Heterozygous Mice

    Baldauf, C., Jeschke, A., Kanbach, V., Catala-Lehnen, P., Baumhoer, D., Gerull, H., Buhs, S., Amling, M., Nollau, P., Harroch, S. & Schinke, T., 2015, In: PLOS ONE. 10, 9, p. e0137745

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. 2014
  15. Midkine-deficiency delays chondrogenesis during the early phase of fracture healing in mice

    Haffner-Luntzer, M., Heilmann, A., Rapp, A. E., Beie, S., Schinke, T., Amling, M., Ignatius, A. & Liedert, A., 31.12.2014, In: PLOS ONE. 9, 12, p. e116282

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL

    Schieferdecker, A., Voigt, M., Riecken, K., Braig, F., Schinke, T., Loges, S., Bokemeyer, C., Fehse, B. & Binder, M., 30.08.2014, In: ONCOTARGET. 5, 16, p. 6647-53 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Osteoblast-specific Krm2 overexpression and Lrp5 deficiency have different effects on fracture healing in mice

    Liedert, A., Röntgen, V., Schinke, T., Benisch, P., Ebert, R., Jakob, F., Klein-Hitpass, L., Lennerz, J. K., Amling, M. & Ignatius, A., 25.07.2014, In: PLOS ONE. 9, 7, p. e103250

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Relevance of Wnt signaling for osteoanabolic therapy

    Yorgan, T. A. & Schinke, T., 14.07.2014, In: Mol Cell Ther. 2, 1, p. 22

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Inhibition of bone remodeling in young mice by bisphosphonate displaces the plasma cell niche into the spleen

    Teufel, S., Grötsch, B., Luther, J., Derer, A., Schinke, T., Amling, M., Schett, G., Mielenz, D. & David, J-P., 01.07.2014, In: J IMMUNOL. 193, 1, p. 223-233 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Effects of extracellular phosphate on gene expression in murine osteoblasts

    Rendenbach, C., Yorgan, T. A., Heckt, T., Otto, B., Baldauf, C., Jeschke, A., Streichert, T., David, J. P., Amling, M. & Schinke, T., 01.05.2014, In: CALCIFIED TISSUE INT. 94, 5, p. 474-83 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity

    Bartelt, A., Beil, T., Müller, B., Koehne, T., Yorgan, T. A., Heine, M., Yilmaz, T., Ruether, W., Heeren, J., Schinke, T. & Niemeier, A., 01.05.2014, In: BONE. 62, p. 90-98 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. CLCN7 and TCIRG1 mutations differentially affect bone matrix mineralization in osteopetrotic individuals

    Barvencik, F., Kurth, I., Koehne, T., Stauber, T., Zustin, J., Tsiakas, K., Ludwig, C. F., Beil, F. T., Pestka, J-M., Hahn, M., Santer, R., Supanchart, C., Kornak, U., Del Fattore, A., Jentsch, T. J., Teti, A., Schulz, A., Schinke, T. & Amling, M., 01.04.2014, In: J BONE MINER RES. 29, 4, p. 982-91 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Sensory neuropathy with bone destruction due to a mutation in the membrane-shaping atlastin GTPase 3

    Kornak, U., Mademan, I., Schinke, M., Voigt, M., Krawitz, P., Hecht, J., Barvencik, F., Schinke, T., Gießelmann, S., Beil, F. T., Pou-Serradell, A., Vílchez, J. J., Beetz, C., Deconinck, T., Timmerman, V., Kaether, C., De Jonghe, P., Hübner, C. A., Gal, A., Amling, M., Mundlos, S., Baets, J. & Kurth, I., 01.03.2014, In: BRAIN. 137, 3, p. 683-92 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. The role of midkine in skeletal remodelling

    Liedert, A., Schinke, T., Ignatius, A. & Amling, M., 01.02.2014, In: BRIT J PHARMACOL. 171, 4, p. 870-878 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Increased Osteoclastogenesis in Mice Lacking the Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1

    Heckt, T., Bickert, T., Jeschke, A., Seitz, S., Schulze, J., Ito, W. D., Zimmermann, W., Amling, M., Schinke, T., Horst, A. K. & Keller, J., 01.01.2014, In: PLOS ONE. 9, 12, p. e114360

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts

    Keller, J., Catala-Lehnen, P., Hübner, A. K., Jeschke, A., Heckt, T., Lueth, A., Krause, M., Koehne, T., Albers, J., Schulze, J., Schilling, S., Haberland, M., Denninger, H., Neven, M., Hermans-Borgmeyer, I., Streichert, T., Breer, S., Barvencik, F., Levkau, B., Rathkolb, B., Wolf, E., Calzada-Wack, J., Neff, F., Gailus-Durner, V., Fuchs, H., de Angelis, M. H., Klutmann, S., Tsourdi, E., Hofbauer, L. C., Kleuser, B., Chun, J., Schinke, T. & Amling, M., 2014, In: NAT COMMUN. 5, p. 5215

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. 2013
  28. Increased Col10a1 expression is not causative for the phenotype of Phex-deficient Hyp mice

    Yorgan, T., Rendenbach, C., Jeschke, A., Amling, M., Cheah, K. S. E. & Schinke, T., 13.12.2013, In: BIOCHEM BIOPH RES CO. 442, 3-4, p. 209-13 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Decreased bone formation and increased osteoclastogenesis cause bone loss in mucolipidosis II

    Kollmann, K., Pestka, J-M., Kühn, S. C., Schöne, E., Schweizer, M., Karkmann, K., Otomo, T., Catala-Lehnen, P., Failla, A. V., Marshall, R. P., Krause, M., Santer, R., Amling, M., Braulke, T. & Schinke, T., 01.12.2013, In: EMBO MOL MED. 5, 12, p. 1871-86 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism

    Bozec, A., Bakiri, L., Jimenez, M., Rosen, E. D., Catalá-Lehnen, P., Schinke, T., Schett, G., Amling, M. & Wagner, E. F., 01.12.2013, In: J CELL SCI. 126, Pt 23, p. 5432-40 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Systemic treatment with the sphingosine-1-phosphate analog FTY720 does not improve fracture healing in mice

    Heilmann, A., Schinke, T., Bindl, R., Wehner, T., Rapp, A., Haffner-Luntzer, M., Liedert, A., Amling, M. & Ignatius, A., 01.11.2013, In: J ORTHOP RES. 31, 11, p. 1845-50 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. The role of the gastrointestinal tract in calcium homeostasis and bone remodeling

    Keller, J. & Schinke, T., 01.11.2013, In: OSTEOPOROSIS INT. 24, 11, p. 2737-48 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5)

    Wintges, K., Beil, F. T., Albers, J., Jeschke, A., Schweizer, M., Claass, B., Tiegs, G., Amling, M. & Schinke, T., 01.10.2013, In: J BONE MINER RES. 28, 10, p. 2070-80 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Increased osteoblast and osteoclast indices in individuals with systemic mastocytosis

    Seitz, S., Barvencik, F., Koehne, T., Priemel, M., Pogoda, P., Semler, J., Minne, H., Pfeiffer, M., Zustin, J., Püschel, K., zu Eulenburg, C., Schinke, T. & Amling, M., 01.08.2013, In: OSTEOPOROSIS INT. 24, 8, p. 2325-34 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Osteocalcin is associated with testosterone in the general population and selected patients with bone disorders

    Hannemann, A., Breer, S., Wallaschofski, H., Nauck, M., Baumeister, S. E., Barvencik, F., Amling, M., Schinke, T., Haring, R. & Keller, J., 01.05.2013, In: ANDROLOGY-US. 1, 3, p. 469-74 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Mutations in WNT1 cause different forms of bone fragility

    Keupp, K., Beleggia, F., Kayserili, H., Barnes, A. M., Steiner, M., Semler, O., Fischer, B., Yigit, G., Janda, C. Y., Becker, J., Breer, S., Altunoglu, U., Grünhagen, J., Krawitz, P., Hecht, J., Schinke, T., Makareeva, E., Lausch, E., Cankaya, T., Caparrós-Martín, J. A., Lapunzina, P., Temtamy, S., Aglan, M., Zabel, B., Eysel, P., Koerber, F., Leikin, S., Garcia, K. C., Netzer, C., Schönau, E., Ruiz-Perez, V. L., Mundlos, S., Amling, M., Kornak, U., Marini, J. & Wollnik, B., 04.04.2013, In: AM J HUM GENET. 92, 4, p. 565-74 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin

    Albers, J., Keller, J., Baranowsky, A., Beil, F. T., Catala-Lehnen, P., Schulze, J., Amling, M. & Schinke, T., 18.02.2013, In: J CELL BIOL. 200, 4, p. 537-49 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. The Wnt serpentine receptor Frizzled-9 regulates new bone formation in fracture healing

    Heilmann, A., Schinke, T., Bindl, R., Wehner, T., Rapp, A., Haffner-Luntzer, M., Nemitz, C., Liedert, A., Amling, M. & Ignatius, A., 01.01.2013, In: PLOS ONE. 8, 12, p. e84232

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Impaired bone mineralization accompanied by low vitamin D and secondary hyperparathyroidism in patients with femoral neck fracture.

    Seitz, S., Koehne, T., Ries, C., Novo De Oliveira, A., Barvencik, F., Busse, B., zu Eulenburg, C., Schinke, T., Püschel, K., Rueger, J. M., Amling, M. & Pogoda, P., 2013, In: OSTEOPOROSIS INT. 24, 2, p. 641-649 9 p., 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Increased expression of transthyretin in leptin-deficient ob/ob mice is not causative for their major phenotypic abnormalities.

    Rendenbach, C., Ganswindt, S., Seitz, S., Barvencik, F., Hübner, A. K., Baranowsky, A., Streichert, T., Niemeier, A., Heeren, J., Amling, M., Bartelt, A. & Schinke, T., 2013, In: J NEUROENDOCRINOL. 25, 1, p. 14-22 9 p., 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Osteopetrosis, osteopetrorickets and hypophosphatemic rickets differentially affect dentin and enamel mineralization.

    Koehne, T., Marshall, R. P., Jeschke, A., Kahl-Nieke, B., Schinke, T. & Amling, M., 2013, In: BONE. 53, 1, p. 25-33 9 p., 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Retinol deprivation partially rescues the skeletal mineralization defects of Phex-deficient Hyp mice.

    Seitz, S., Rendenbach, C., Barvencik, F., Streichert, T., Jeschke, A., Schulze, J., Amling, M. & Schinke, T., 2013, In: BONE. 53, 1, p. 231-238 8 p., 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. 2012
  44. Accelerated growth plate mineralization and foreshortened proximal limb bones in fetuin-A knockout mice

    Seto, J., Busse, B., Gupta, H. S., Schäfer, C., Krauss, S., Dunlop, J. W. C., Masic, A., Kerschnitzki, M., Zaslansky, P., Boesecke, P., Catalá-Lehnen, P., Schinke, T., Fratzl, P. & Jahnen-Dechent, W., 01.01.2012, In: PLOS ONE. 7, 10, p. e47338

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Pharmacological estrogen administration causes a FSH-independent osteo-anabolic effect requiring ER alpha in osteoblasts

    Seitz, S., Keller, J., Schilling, A. F., Jeschke, A., Marshall, R. P., Stride, B. D., Wintermantel, T., Beil, F. T., Amling, M., Schütz, G., Tuckermann, J. & Schinke, T., 01.01.2012, In: PLOS ONE. 7, 11, p. e50301

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Divergent resorbability and effects on osteoclast formation of commonly used bone substitutes in a human in vitro-assay.

    Keller, J., Brink, S., Busse, B., Schilling, A., Schinke, T., Amling, M. & Lange, T., 2012, In: PLOS ONE. 7, 10, p. 46757 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Estradiol increases hematopoietic stem and progenitor cells independent of its actions on bone.

    Illing, A., Liu, P., Ostermay, S., Schilling, A., de Haan, G., Krust, A., Amling, M., Chambon, P., Schinke, T. & Tuckermann, J. P., 2012, In: HAEMATOLOGICA. 97, 8, p. 1131-1135 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Low turnover osteoporosis in sheep induced by hypothalamic-pituitary disconnection.

    Beil, F. T., Oheim, R., Barvencik, F., Hissnauer, T. N., Pestka, J-M., Ignatius, A., Rueger, J. M., Schinke, T., Clarke, I. J., Amling, M. & Pogoda, P., 2012, In: J ORTHOP RES. 30, 8, p. 1254-1262 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Mice over-expressing salmon calcitonin have strongly attenuated osteoarthritic histopathological changes after destabilization of the medial meniscus.

    Sondergaard, B. C., Catalá-Lehnen, P., Hübner, A. K., Bay-Jensen, A-C., Schinke, T., Henriksen, K., Schilling, A., Haberland, M., Nielsen, R. H., Amling, M. & Karsdal, M. A., 2012, In: OSTEOARTHR CARTILAGE. 20, 2, p. 136-143 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. p65-Dependent production of interleukin-1β by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts.

    Schulze, J., Riecken, K., Baranowsky, A., Streichert, T., Lange, T., Spiro, A. S., Albers, J., Seitz, S., Zustin, J., Amling, M., Fehse, B. & Schinke, T., 2012, In: CANCER LETT. 317, 1, p. 106-113 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. The role of apolipoprotein E in bone metabolism.

    Niemeier, A., Schinke, T., Heeren, J. & Amling, M., 2012, In: BONE. 50, 2, p. 518-524 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors.

    Benisch, P., Schilling, T., Klein-Hitpass, L., Frey, S. P., Seefried, L., Raaijmakers, N., Krug, M., Regensburger, M., Zeck, S., Schinke, T., Amling, M., Ebert, R. & Jakob, F., 2012, In: PLOS ONE. 7, 9, p. 45142 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. Transgenic over-expression of interleukin-33 in osteoblasts results in decreased osteoclastogenesis.

    Keller, J., Catalá-Lehnen, P., Wintges, K., Schulze, J., Bickert, T., Ito, W., Horst, A., Amling, M. & Schinke, T., 2012, In: BIOCHEM BIOPH RES CO. 417, 1, p. 217-222 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  54. WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production.

    Rauner, M., Stein, N., Winzer, M., Goettsch, C., Zwerina, J., Schett, G., Distler, J. H. W., Albers, J., Schulze, J., Schinke, T., Bornhäuser, M., Platzbecker, U. & Hofbauer, L. C., 2012, In: J BONE MINER RES. 27, 3, p. 575-585 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  55. 2011
  56. Control of bone formation by the serpentine receptor Frizzled-9.

    Albers, J., Schulze, J., Beil, F. T., Gebauer, M., Baranowsky, A., Keller, J., Marshall, R-P., Wintges, K., Friedrich, F., Priemel, M., Schilling, A., Rueger, J. M., Cornils, K., Fehse, B., Streichert, T., Sauter, G., Jakob, F., Insogna, K. L., Pober, B., Knobeloch, K-P., Francke, U., Amling, M. & Schinke, T., 2011, In: J CELL BIOL. 192, 6, p. 1057-1072 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review