Prof.Dr.rer.nat ID: 73722
Thorsten Schinke
Publications
- 2016
No obvious phenotypic abnormalities in mice lacking the Pate4 gene
Heckt, T., Keller, J., Reusch, R., Hartmann, K., Krasemann, S., Hermans-Borgmeyer, I., Amling, M. & Schinke, T., 22.01.2016, In: BIOCHEM BIOPH RES CO. 469, 4, p. 1069-1074Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Can we induce osteoporosis in animals comparable to the human situation?
Oheim, R., Schinke, T., Amling, M. & Pogoda, P., 01.2016, In: INJURY. 47 Suppl 1, p. S3-9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Die endokrine Funktion der Osteozyten
Yorgan, T. & Schinke, T., 2016, In: OSTEOLOGIE. 25, 2, p. 62-68 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inhibition of Midkine Augments Osteoporotic Fracture Healing
Haffner-Luntzer, M., Kemmler, J., Heidler, V., Prystaz, K., Schinke, T., Amling, M., Kovtun, A., Rapp, A. E., Ignatius, A. & Liedert, A., 2016, In: PLOS ONE. 11, 7, p. e0159278Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I
Kühn, S. C., Koehne, T., Cornils, K., Markmann, S., Riedel, C., Pestka, J. M., Schweizer, M., Baldauf, C., Yorgan, T. A., Krause, M., Keller, J., Neven, M., Breyer, S., Stücker, R., Muschol, N., Busse, B., Braulke, T., Fehse, B., Amling, M. & Schinke, T., 15.12.2015, In: HUM MOL GENET. 24, 24, p. 7075-7086Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells
Jeschke, A., Catala-Lehnen, P., Sieber, S., Bickert, T., Schweizer, M., Koehne, T., Wintges, K., Marshall, R. P., Mautner, A., Duchstein, L., Otto, B., Horst, A. K., Amling, M., Kreienkamp, H-J. & Schinke, T., 15.10.2015, In: J IMMUNOL. 195, 8, p. 3675-84 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Anti-Osteoanabolic Function of Sclerostin is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5
Yorgan, T. A., Peters, S., Jeschke, A., Benisch, P., Jakob, F., Amling, M. & Schinke, T., 07.2015, In: J BONE MINER RES. 30, 7, p. 1175-1183Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Calcium gluconate supplementation is effective to balance calcium homeostasis in patients with gastrectomy
Krause, M., Keller, J., Beil, B., van Driel, I., Zustin, J., Barvencik, F., Schinke, T. & Amling, M., 03.2015, In: OSTEOPOROSIS INT. 26, 3, p. 987-95 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The impact of low-magnitude high-frequency vibration on fracture healing is profoundly influenced by the oestrogen status in mice
Wehrle, E., Liedert, A., Heilmann, A., Wehner, T., Bindl, R., Fischer, L., Haffner-Luntzer, M., Jakob, F., Schinke, T., Amling, M. & Ignatius, A., 01.2015, In: DIS MODEL MECH. 8, 1, p. 93-104 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deficiency of Thrombospondin-4 in Mice Does Not Affect Skeletal Growth or Bone Mass Acquisition, but Causes a Transient Reduction of Articular Cartilage Thickness
Jeschke, A., Bonitz, M., Simon, M., Peters, S., Baum, W., Schett, G., Ruether, W., Niemeier, A., Schinke, T. & Amling, M., 2015, In: PLOS ONE. 10, 12, p. e0144272Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Protein Tyrosine Phosphatase Rptpζ Suppresses Osteosarcoma Development in Trp53-Heterozygous Mice
Baldauf, C., Jeschke, A., Kanbach, V., Catala-Lehnen, P., Baumhoer, D., Gerull, H., Buhs, S., Amling, M., Nollau, P., Harroch, S. & Schinke, T., 2015, In: PLOS ONE. 10, 9, p. e0137745Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Midkine-deficiency delays chondrogenesis during the early phase of fracture healing in mice
Haffner-Luntzer, M., Heilmann, A., Rapp, A. E., Beie, S., Schinke, T., Amling, M., Ignatius, A. & Liedert, A., 31.12.2014, In: PLOS ONE. 9, 12, p. e116282Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL
Schieferdecker, A., Voigt, M., Riecken, K., Braig, F., Schinke, T., Loges, S., Bokemeyer, C., Fehse, B. & Binder, M., 30.08.2014, In: ONCOTARGET. 5, 16, p. 6647-53 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Osteoblast-specific Krm2 overexpression and Lrp5 deficiency have different effects on fracture healing in mice
Liedert, A., Röntgen, V., Schinke, T., Benisch, P., Ebert, R., Jakob, F., Klein-Hitpass, L., Lennerz, J. K., Amling, M. & Ignatius, A., 25.07.2014, In: PLOS ONE. 9, 7, p. e103250Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevance of Wnt signaling for osteoanabolic therapy
Yorgan, T. A. & Schinke, T., 14.07.2014, In: Mol Cell Ther. 2, 1, p. 22Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inhibition of bone remodeling in young mice by bisphosphonate displaces the plasma cell niche into the spleen
Teufel, S., Grötsch, B., Luther, J., Derer, A., Schinke, T., Amling, M., Schett, G., Mielenz, D. & David, J-P., 01.07.2014, In: J IMMUNOL. 193, 1, p. 223-233 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effects of extracellular phosphate on gene expression in murine osteoblasts
Rendenbach, C., Yorgan, T. A., Heckt, T., Otto, B., Baldauf, C., Jeschke, A., Streichert, T., David, J. P., Amling, M. & Schinke, T., 01.05.2014, In: CALCIFIED TISSUE INT. 94, 5, p. 474-83 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity
Bartelt, A., Beil, T., Müller, B., Koehne, T., Yorgan, T. A., Heine, M., Yilmaz, T., Ruether, W., Heeren, J., Schinke, T. & Niemeier, A., 01.05.2014, In: BONE. 62, p. 90-98 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CLCN7 and TCIRG1 mutations differentially affect bone matrix mineralization in osteopetrotic individuals
Barvencik, F., Kurth, I., Koehne, T., Stauber, T., Zustin, J., Tsiakas, K., Ludwig, C. F., Beil, F. T., Pestka, J-M., Hahn, M., Santer, R., Supanchart, C., Kornak, U., Del Fattore, A., Jentsch, T. J., Teti, A., Schulz, A., Schinke, T. & Amling, M., 01.04.2014, In: J BONE MINER RES. 29, 4, p. 982-91 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sensory neuropathy with bone destruction due to a mutation in the membrane-shaping atlastin GTPase 3
Kornak, U., Mademan, I., Schinke, M., Voigt, M., Krawitz, P., Hecht, J., Barvencik, F., Schinke, T., Gießelmann, S., Beil, F. T., Pou-Serradell, A., Vílchez, J. J., Beetz, C., Deconinck, T., Timmerman, V., Kaether, C., De Jonghe, P., Hübner, C. A., Gal, A., Amling, M., Mundlos, S., Baets, J. & Kurth, I., 01.03.2014, In: BRAIN. 137, 3, p. 683-92 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The role of midkine in skeletal remodelling
Liedert, A., Schinke, T., Ignatius, A. & Amling, M., 01.02.2014, In: BRIT J PHARMACOL. 171, 4, p. 870-878 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased Osteoclastogenesis in Mice Lacking the Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1
Heckt, T., Bickert, T., Jeschke, A., Seitz, S., Schulze, J., Ito, W. D., Zimmermann, W., Amling, M., Schinke, T., Horst, A. K. & Keller, J., 01.01.2014, In: PLOS ONE. 9, 12, p. e114360Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts
Keller, J., Catala-Lehnen, P., Hübner, A. K., Jeschke, A., Heckt, T., Lueth, A., Krause, M., Koehne, T., Albers, J., Schulze, J., Schilling, S., Haberland, M., Denninger, H., Neven, M., Hermans-Borgmeyer, I., Streichert, T., Breer, S., Barvencik, F., Levkau, B., Rathkolb, B., Wolf, E., Calzada-Wack, J., Neff, F., Gailus-Durner, V., Fuchs, H., de Angelis, M. H., Klutmann, S., Tsourdi, E., Hofbauer, L. C., Kleuser, B., Chun, J., Schinke, T. & Amling, M., 2014, In: NAT COMMUN. 5, p. 5215Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Increased Col10a1 expression is not causative for the phenotype of Phex-deficient Hyp mice
Yorgan, T., Rendenbach, C., Jeschke, A., Amling, M., Cheah, K. S. E. & Schinke, T., 13.12.2013, In: BIOCHEM BIOPH RES CO. 442, 3-4, p. 209-13 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Decreased bone formation and increased osteoclastogenesis cause bone loss in mucolipidosis II
Kollmann, K., Pestka, J-M., Kühn, S. C., Schöne, E., Schweizer, M., Karkmann, K., Otomo, T., Catala-Lehnen, P., Failla, A. V., Marshall, R. P., Krause, M., Santer, R., Amling, M., Braulke, T. & Schinke, T., 01.12.2013, In: EMBO MOL MED. 5, 12, p. 1871-86 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism
Bozec, A., Bakiri, L., Jimenez, M., Rosen, E. D., Catalá-Lehnen, P., Schinke, T., Schett, G., Amling, M. & Wagner, E. F., 01.12.2013, In: J CELL SCI. 126, Pt 23, p. 5432-40 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Systemic treatment with the sphingosine-1-phosphate analog FTY720 does not improve fracture healing in mice
Heilmann, A., Schinke, T., Bindl, R., Wehner, T., Rapp, A., Haffner-Luntzer, M., Liedert, A., Amling, M. & Ignatius, A., 01.11.2013, In: J ORTHOP RES. 31, 11, p. 1845-50 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The role of the gastrointestinal tract in calcium homeostasis and bone remodeling
Keller, J. & Schinke, T., 01.11.2013, In: OSTEOPOROSIS INT. 24, 11, p. 2737-48 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5)
Wintges, K., Beil, F. T., Albers, J., Jeschke, A., Schweizer, M., Claass, B., Tiegs, G., Amling, M. & Schinke, T., 01.10.2013, In: J BONE MINER RES. 28, 10, p. 2070-80 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased osteoblast and osteoclast indices in individuals with systemic mastocytosis
Seitz, S., Barvencik, F., Koehne, T., Priemel, M., Pogoda, P., Semler, J., Minne, H., Pfeiffer, M., Zustin, J., Püschel, K., zu Eulenburg, C., Schinke, T. & Amling, M., 01.08.2013, In: OSTEOPOROSIS INT. 24, 8, p. 2325-34 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Osteocalcin is associated with testosterone in the general population and selected patients with bone disorders
Hannemann, A., Breer, S., Wallaschofski, H., Nauck, M., Baumeister, S. E., Barvencik, F., Amling, M., Schinke, T., Haring, R. & Keller, J., 01.05.2013, In: ANDROLOGY-US. 1, 3, p. 469-74 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutations in WNT1 cause different forms of bone fragility
Keupp, K., Beleggia, F., Kayserili, H., Barnes, A. M., Steiner, M., Semler, O., Fischer, B., Yigit, G., Janda, C. Y., Becker, J., Breer, S., Altunoglu, U., Grünhagen, J., Krawitz, P., Hecht, J., Schinke, T., Makareeva, E., Lausch, E., Cankaya, T., Caparrós-Martín, J. A., Lapunzina, P., Temtamy, S., Aglan, M., Zabel, B., Eysel, P., Koerber, F., Leikin, S., Garcia, K. C., Netzer, C., Schönau, E., Ruiz-Perez, V. L., Mundlos, S., Amling, M., Kornak, U., Marini, J. & Wollnik, B., 04.04.2013, In: AM J HUM GENET. 92, 4, p. 565-74 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin
Albers, J., Keller, J., Baranowsky, A., Beil, F. T., Catala-Lehnen, P., Schulze, J., Amling, M. & Schinke, T., 18.02.2013, In: J CELL BIOL. 200, 4, p. 537-49 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Wnt serpentine receptor Frizzled-9 regulates new bone formation in fracture healing
Heilmann, A., Schinke, T., Bindl, R., Wehner, T., Rapp, A., Haffner-Luntzer, M., Nemitz, C., Liedert, A., Amling, M. & Ignatius, A., 01.01.2013, In: PLOS ONE. 8, 12, p. e84232Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impaired bone mineralization accompanied by low vitamin D and secondary hyperparathyroidism in patients with femoral neck fracture.
Seitz, S., Koehne, T., Ries, C., Novo De Oliveira, A., Barvencik, F., Busse, B., zu Eulenburg, C., Schinke, T., Püschel, K., Rueger, J. M., Amling, M. & Pogoda, P., 2013, In: OSTEOPOROSIS INT. 24, 2, p. 641-649 9 p., 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased expression of transthyretin in leptin-deficient ob/ob mice is not causative for their major phenotypic abnormalities.
Rendenbach, C., Ganswindt, S., Seitz, S., Barvencik, F., Hübner, A. K., Baranowsky, A., Streichert, T., Niemeier, A., Heeren, J., Amling, M., Bartelt, A. & Schinke, T., 2013, In: J NEUROENDOCRINOL. 25, 1, p. 14-22 9 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Osteopetrosis, osteopetrorickets and hypophosphatemic rickets differentially affect dentin and enamel mineralization.
Koehne, T., Marshall, R. P., Jeschke, A., Kahl-Nieke, B., Schinke, T. & Amling, M., 2013, In: BONE. 53, 1, p. 25-33 9 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retinol deprivation partially rescues the skeletal mineralization defects of Phex-deficient Hyp mice.
Seitz, S., Rendenbach, C., Barvencik, F., Streichert, T., Jeschke, A., Schulze, J., Amling, M. & Schinke, T., 2013, In: BONE. 53, 1, p. 231-238 8 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
Accelerated growth plate mineralization and foreshortened proximal limb bones in fetuin-A knockout mice
Seto, J., Busse, B., Gupta, H. S., Schäfer, C., Krauss, S., Dunlop, J. W. C., Masic, A., Kerschnitzki, M., Zaslansky, P., Boesecke, P., Catalá-Lehnen, P., Schinke, T., Fratzl, P. & Jahnen-Dechent, W., 01.01.2012, In: PLOS ONE. 7, 10, p. e47338Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pharmacological estrogen administration causes a FSH-independent osteo-anabolic effect requiring ER alpha in osteoblasts
Seitz, S., Keller, J., Schilling, A. F., Jeschke, A., Marshall, R. P., Stride, B. D., Wintermantel, T., Beil, F. T., Amling, M., Schütz, G., Tuckermann, J. & Schinke, T., 01.01.2012, In: PLOS ONE. 7, 11, p. e50301Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Divergent resorbability and effects on osteoclast formation of commonly used bone substitutes in a human in vitro-assay.
Keller, J., Brink, S., Busse, B., Schilling, A., Schinke, T., Amling, M. & Lange, T., 2012, In: PLOS ONE. 7, 10, p. 46757 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Estradiol increases hematopoietic stem and progenitor cells independent of its actions on bone.
Illing, A., Liu, P., Ostermay, S., Schilling, A., de Haan, G., Krust, A., Amling, M., Chambon, P., Schinke, T. & Tuckermann, J. P., 2012, In: HAEMATOLOGICA. 97, 8, p. 1131-1135 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low turnover osteoporosis in sheep induced by hypothalamic-pituitary disconnection.
Beil, F. T., Oheim, R., Barvencik, F., Hissnauer, T. N., Pestka, J-M., Ignatius, A., Rueger, J. M., Schinke, T., Clarke, I. J., Amling, M. & Pogoda, P., 2012, In: J ORTHOP RES. 30, 8, p. 1254-1262 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mice over-expressing salmon calcitonin have strongly attenuated osteoarthritic histopathological changes after destabilization of the medial meniscus.
Sondergaard, B. C., Catalá-Lehnen, P., Hübner, A. K., Bay-Jensen, A-C., Schinke, T., Henriksen, K., Schilling, A., Haberland, M., Nielsen, R. H., Amling, M. & Karsdal, M. A., 2012, In: OSTEOARTHR CARTILAGE. 20, 2, p. 136-143 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
p65-Dependent production of interleukin-1β by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts.
Schulze, J., Riecken, K., Baranowsky, A., Streichert, T., Lange, T., Spiro, A. S., Albers, J., Seitz, S., Zustin, J., Amling, M., Fehse, B. & Schinke, T., 2012, In: CANCER LETT. 317, 1, p. 106-113 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The role of apolipoprotein E in bone metabolism.
Niemeier, A., Schinke, T., Heeren, J. & Amling, M., 2012, In: BONE. 50, 2, p. 518-524 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors.
Benisch, P., Schilling, T., Klein-Hitpass, L., Frey, S. P., Seefried, L., Raaijmakers, N., Krug, M., Regensburger, M., Zeck, S., Schinke, T., Amling, M., Ebert, R. & Jakob, F., 2012, In: PLOS ONE. 7, 9, p. 45142 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transgenic over-expression of interleukin-33 in osteoblasts results in decreased osteoclastogenesis.
Keller, J., Catalá-Lehnen, P., Wintges, K., Schulze, J., Bickert, T., Ito, W., Horst, A., Amling, M. & Schinke, T., 2012, In: BIOCHEM BIOPH RES CO. 417, 1, p. 217-222 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production.
Rauner, M., Stein, N., Winzer, M., Goettsch, C., Zwerina, J., Schett, G., Distler, J. H. W., Albers, J., Schulze, J., Schinke, T., Bornhäuser, M., Platzbecker, U. & Hofbauer, L. C., 2012, In: J BONE MINER RES. 27, 3, p. 575-585 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Control of bone formation by the serpentine receptor Frizzled-9.
Albers, J., Schulze, J., Beil, F. T., Gebauer, M., Baranowsky, A., Keller, J., Marshall, R-P., Wintges, K., Friedrich, F., Priemel, M., Schilling, A., Rueger, J. M., Cornils, K., Fehse, B., Streichert, T., Sauter, G., Jakob, F., Insogna, K. L., Pober, B., Knobeloch, K-P., Francke, U., Amling, M. & Schinke, T., 2011, In: J CELL BIOL. 192, 6, p. 1057-1072 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review