Research ExplorerScientific StaffRichard Drexler Publications

ID: 15062826

Richard Drexler

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Affiliations
ORCID: 0000-0002-4830-3671
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Publications

  1. 2024

  2. Mean global DNA methylation serves as independent prognostic marker in IDH wild type glioblastoma

    Eckhardt, A., Drexler, R., Schoof, M., Struve, N., Capper, D., Jelgersma, C., Onken, J., Harter, P. N., Weber, K. J., Divé, I., Rothkamm, K., Hoffer, K., Klumpp, L., Ganser, K., Petersen, C., Ricklefs, F., Kriegs, M. & Schüller, U., 04.03.2024, In: NEURO-ONCOLOGY. 26, 3, p. 503-513 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma

    Drexler, R., Khatri, R., Schüller, U., Eckhardt, A., Ryba, A., Sauvigny, T., Dührsen, L., Mohme, M., Ricklefs, T., Bode, H., Hausmann, F., Huber, T. B., Bonn, S., Voß, H., Neumann, J. E., Silverbush, D., Hovestadt, V., Suvà, M. L., Lamszus, K., Gempt, J., Westphal, M., Heiland, D. H., Hänzelmann, S. & Ricklefs, F. L., 20.01.2024, In: ACTA NEUROPATHOL. 147, 1, p. 21

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Unclassifiable CNS tumors in DNA methylation-based classification: clinical challenges and prognostic impact

    Drexler, R., Brembach, F., Sauvigny, J., Ricklefs, F. L., Eckhardt, A., Bode, H., Gempt, J., Lamszus, K., Westphal, M., Schüller, U. & Mohme, M., 16.01.2024, In: ACTA NEUROPATHOL COM. 12, 1, p. 9

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. 2023

  6. Machine learning based outcome prediction of microsurgically treated unruptured intracranial aneurysms

    Stroh, N., Stefanits, H., Maletzky, A., Kaltenleithner, S., Thumfart, S., Giretzlehner, M., Drexler, R., Ricklefs, F. L., Dührsen, L., Aspalter, S., Rauch, P., Gruber, A. & Gmeiner, M., 19.12.2023, In: SCI REP-UK. 13, 1, p. 22641

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Crooke Cell Adenoma Confers Poorer Endocrinological Outcomes Compared with Corticotroph Adenoma: Results of a Multicenter, International Analysis

    Findlay, M. C., Drexler, R., Azab, M., Karbe, A., Rotermund, R., Ricklefs, F. L., Flitsch, J., Smith, T. R., Kilgallon, J. L., Honegger, J., Nasi-Kordhishti, I., Gardner, P. A., Gersey, Z. C., Abdallah, H. M., Jane, J. A., Marino, A. C., Knappe, U. J., Uksul, N., Rzaev, J. A., Bervitskiy, A. V., Schroeder, H. W. S., Eördögh, M., Losa, M., Mortini, P., Gerlach, R., Antunes, A. C. M., Couldwell, W. T., Budohoski, K. P., Rennert, R. C. & Karsy, M., 12.2023, In: WORLD NEUROSURG. 180, p. e376-e391 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. In Reply: A Multicenter, Propensity Score-Matched Assessment of Endoscopic Versus Microscopic Approaches in the Management of Pituitary Adenomas

    Findlay, M. C., Drexler, R. & Karsy, M., 01.11.2023, In: NEUROSURGERY. 93, 5, p. e135-e136 2 p.

    Research output: SCORING: Contribution to journal › Letter › Research › peer-review

  9. A Multicenter, Propensity Score-Matched Assessment of Endoscopic Versus Microscopic Approaches in the Management of Pituitary Adenomas

    Findlay, M. C., Drexler, R., Khan, M., Cole, K. L., Karbe, A., Rotermund, R., Ricklefs, F. L., Flitsch, J., Smith, T. R., Kilgallon, J. L., Honegger, J., Nasi-Kordhishti, I., Gardner, P. A., Gersey, Z. C., Abdallah, H. M., Jane, J. A., Marino, A. C., Knappe, U. J., Uksul, N., Rzaev, J. A., Galushko, E. V., Gormolysova, E. V., Bervitskiy, A. V., Schroeder, H. W. S., Eördögh, M., Losa, M., Mortini, P., Gerlach, R., Antunes, A. C. M., Couldwell, W. T., Budohoski, K. P., Rennert, R. C., Azab, M. & Karsy, M., 01.10.2023, In: NEUROSURGERY. 93, 4, p. 794-801 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Epigenetic profiling reveals a strong association between lack of 5-ALA fluorescence and EGFR amplification in IDH-wildtype glioblastoma

    Drexler, R., Sauvigny, T., Schüller, U., Eckhardt, A., Maire, C. L., Khatri, R., Hausmann, F., Hänzelmann, S., Huber, T. B., Bonn, S., Bode, H., Lamszus, K., Westphal, M., Dührsen, L. & Ricklefs, F. L., 10.2023, In: NEURO-ONCOL PRACT. 10, 5, p. 462-471 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Defining benchmark outcomes for transsphenoidal surgery of pituitary adenomas: a multicenter analysis

    Drexler, R., Rotermund, R., Smith, T. R., Kilgallon, J. L., Honegger, J., Nasi-Kordhishti, I., Gardner, P. A., Gersey, Z. C., Abdallah, H. M., Jane, J. A., Marino, A. C., Knappe, U. J., Uksul, N., Rzaev, J. A., Galushko, E. V., Gormolysova, E. V., Bervitskiy, A. V., Schroeder, H. W. S., Eördögh, M., Losa, M., Mortini, P., Gerlach, R., Azab, M., Budohoski, K. P., Rennert, R. C., Karsy, M., Couldwell, W. T., Antunes, A. C. M., Westphal, M., Ricklefs, F. L. & Flitsch, J., 01.09.2023, In: EUR J ENDOCRINOL. 189, 3, p. 379-386 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability

    Drexler, R., Khatri, R., Sauvigny, T., Mohme, M., Maire, C. L., Ryba, A., Zghaibeh, Y., Dührsen, L., Salviano-Silva, A., Lamszus, K., Westphal, M., Gempt, J., Wefers, A. K., Neumann, J., Bode, H., Hausmann, F., Huber, T. B., Bonn, S., Jütten, K., Delev, D., Weber, K. J., Harter, P. N., Onken, J., Vajkoczy, P., Capper, D., Wiestler, B., Weller, M., Snijder, B., Buck, A., Weiss, T., Keough, M. B., Ni, L., Monje, M., Silverbush, D., Hovestadt, V., Suvà, M. L., Krishna, S., Hervey-Jumper, S. L., Schüller, U., Heiland, D. H., Hänzelmann, S. & Ricklefs, F. L., 07.08.2023, In: bioRxiv.

    Research output: SCORING: Contribution to journal › Preprint › Research

  13. Association of the classification of intraoperative adverse events (ClassIntra) with complications and neurological outcome after neurosurgical procedures: a prospective cohort study

    Drexler, R., Ricklefs, F. L., Pantel, T., Göttsche, J., Nitzschke, R., Zöllner, C., Westphal, M. & Dührsen, L., 08.2023, In: ACTA NEUROCHIR. 165, 8, p. 2015-2027 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Targeted anticonvulsive treatment of IDH-wildtype glioblastoma based on DNA methylation subclasses

    Drexler, R., Göttsche, J., Sauvigny, T., Schüller, U., Khatri, R., Hausmann, F., Hänzelmann, S., Huber, T. B., Bonn, S., Heiland, D. H., Delev, D., Venkataramani, V., Winkler, F., Weller, J., Zeyen, T., Herrlinger, U., Gempt, J., Ricklefs, F. L. & Dührsen, L., 04.05.2023, In: NEURO-ONCOLOGY. 25, 5, p. 1006-1008 3 p.

    Research output: SCORING: Contribution to journal › Letter › Research › peer-review

  15. Impact of the SARS-CoV-2 pandemic on the survival of patients with high-grade glioma and best practice recommendations

    Vogel, M. M. E., Wagner, A., Gempt, J., Krenzlin, H., Zeyen, T., Drexler, R., Voss, M., Nettekoven, C., Abboud, T., Mielke, D., Rohde, V., Timmer, M., Goldbrunner, R., Steinbach, J. P., Dührsen, L., Westphal, M., Herrlinger, U., Ringel, F., Meyer, B. & Combs, S. E., 16.02.2023, In: SCI REP-UK. 13, 1, p. 2766

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. DNA methylation subclasses predict the benefit from gross total tumor resection in IDH-wildtype glioblastoma patients

    Drexler, R., Schüller, U., Eckhardt, A., Filipski, K., Hartung, T. I., Harter, P. N., Divé, I., Forster, M-T., Czabanka, M., Jelgersma, C., Onken, J., Vajkoczy, P., Capper, D., Siewert, C., Sauvigny, T., Lamszus, K., Westphal, M., Dührsen, L. & Ricklefs, F. L., 14.02.2023, In: NEURO-ONCOLOGY. 25, 2, p. 315-325 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. 2022

  18. DNA Methylation subclass Receptor Tyrosine Kinase II (RTK II) is predictive for seizure development in glioblastoma patients

    Ricklefs, F. L., Drexler, R., Wollmann, K., Eckhardt, A., Heiland, D. H., Sauvigny, T., Maire, C., Lamszus, K., Westphal, M., Schüller, U. & Dührsen, L., 02.11.2022, In: NEURO-ONCOLOGY. 24, 11, p. 1886-1897 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Single-Center Experience Using a 3D4K Digital Operating Scope System for Aneurysm Surgery

    Pantel, T., Drexler, R., Göttsche, J., Piffko, A., Westphal, M., Regelsberger, J. & Dührsen, L., 01.06.2022, In: OPER NEUROSURG. 22, 6, p. 433-439 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. 2021

  21. Enhancing Safety in Epilepsy Surgery (EASINESS): Study Protocol for a Retrospective, Multicenter, Open Registry

    Drexler, R., Ben-Haim, S., Bien, C. G., Borger, V., Cardinale, F., Carpentier, A., Cendes, F., Chandra, S., Clusmann, H., Colon, A., de Curtis, M., Delev, D., Didato, G., Dührsen, L., Farah, J. O., Guenot, M., Ghatan, S., Haegelen, C., Hamer, H., Hauptmann, J. S., Jeffree, R. L., Kalbhenn, T., Kegele, J., Krayenbühl, N., Lang, J., Mathon, B., Naros, G., Onken, J., Panov, F., Raftopoulos, C., Ricklefs, F. L., Rijkers, K., Rizzi, M., Rössler, K., Schijns, O., Schneider, U. C., Spyrantis, A., Strzelczyk, A., Stodieck, S., Tripathi, M., Vadera, S., Alonso-Vanegas, M. A., Vaz, J. G. R., Wellmer, J., Wehner, T., Westphal, M. & Sauvigny, T., 13.12.2021, In: FRONT NEUROL. 12, 782666.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Impact of acute kidney injury after extended liver resections

    Reese, T., Kröger, F., Makridis, G., Drexler, R., Jusufi, M., Schneider, M., Brüning, R., von Rittberg, Y., Wagner, K. C. & Oldhafer, K. J., 07.2021, In: HPB. 23, 7, p. 1000-1007 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. The clinical relevance of the Hippo pathway in pancreatic ductal adenocarcinoma

    Drexler, R., Küchler, M., Wagner, K. C., Reese, T., Feyerabend, B., Kleine, M. & Oldhafer, K. J., 24.02.2021, In: J CANCER RES CLIN. 147, 2, p. 373-391 19 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Association of subcellular localization of TEAD transcription factors with outcome and progression in pancreatic ductal adenocarcinoma

    Drexler, R., Fahy, R., Küchler, M., Wagner, K. C., Reese, T., Ehmke, M., Feyerabend, B., Kleine, M. & Oldhafer, K. J., 01.2021, In: PANCREATOLOGY. 21, 1, p. 170-179

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. 2020

  26. Establishing a student-run free clinic in a major city in Northern Europe: a 1-year experience from Hamburg, Germany

    Drexler, R., Fröschle, F., Predel, C., Sturm, B., Ustorf, K., Lehner, L., Janzen, J., Valentin, L., Scheer, T., Lehnert, F., Tadzic, R., Oldhafer, K. J. & Meyer, T. N., 23.11.2020, In: J PUBLIC HEALTH-UK. 42, 4, p. 793-798 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Involvement of Medical Students During the Coronavirus Disease 2019 Pandemic: A Cross-Sectional Survey Study

    Drexler, R., Hambrecht, J. M. & Oldhafer, K. J., 30.08.2020, In: CUREUS J MED SCIENCE. 12, 8, e10147.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Significance of unphosphorylated and phosphorylated heat shock protein 27 as a prognostic biomarker in pancreatic ductal adenocarcinoma

    Drexler, R., Wagner, K. C., Küchler, M., Feyerabend, B., Kleine, M. & Oldhafer, K. J., 21.05.2020, In: J CANCER RES CLIN. 146, 5, p. 1125-1137 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review