Research ExplorerScientific StaffNina Struve Publications

Nina Struve

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Publications

  1. 2024

  2. Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level

    Godbole, S., Voß, H., Gocke, A., Schlumbohm, S., Schumann, Y., Peng, B., Mynarek, M., Rutkowski, S., Dottermusch, M., Dorostkar, M. M., Korshunov, A., Mair, T., Pfister, S. M., Kwiatkowski, M., Hotze, M., Neumann, P., Hartmann, C., Weis, J., Liesche-Starnecker, F., Guan, Y., Moritz, M., Siebels, B., Struve, N., Schlüter, H., Schüller, U., Krisp, C. & Neumann, J. E., 24.07.2024, In: NAT COMMUN. 15, 1, p. 6237

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Mean global DNA methylation serves as independent prognostic marker in IDH wild type glioblastoma

    Eckhardt, A., Drexler, R., Schoof, M., Struve, N., Capper, D., Jelgersma, C., Onken, J., Harter, P. N., Weber, K. J., Divé, I., Rothkamm, K., Hoffer, K., Klumpp, L., Ganser, K., Petersen, C., Ricklefs, F., Kriegs, M. & Schüller, U., 04.03.2024, In: NEURO-ONCOLOGY. 26, 3, p. 503-513 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. 2023

  5. Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures

    Schoof, M., Godbole, S., Albert, T. K., Dottermusch, M., Walter, C., Ballast, A., Qin, N., Olivera, M. B., Göbel, C., Neyazi, S., Holdhof, D., Kresbach, C., Peter, L-S., Epplen, G. D., Thaden, V., Spohn, M., Blattner-Johnson, M., Modemann, F., Mynarek, M., Rutkowski, S., Sill, M., Varghese, J., Afflerbach, A-K., Eckhardt, A., Münter, D., Verma, A., Struve, N., Jones, D. T. W., Remke, M., Neumann, J. E., Kerl, K. & Schüller, U., 24.11.2023, In: NAT COMMUN. 14, 1, p. 7717

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Risk prediction in early childhood sonic hedgehog medulloblastoma treated with radiation-avoiding chemotherapy

    Tonn, S., Korshunov, A., Obrecht, D., Sill, M., Spohn, M., von Hoff, K., Milde, T., Pietsch, T., Goschzik, T., Bison, B., Juhnke, B-O., Struve, N., Sturm, D., Sahm, F., Bockmayr, M., Friedrich, C., von Bueren, A. O., Gerber, N. U., Benesch, M., Jones, D. T. W., Kool, M., Wefers, A. K., Schüller, U., Pfister, S. M., Rutkowski, S. & Mynarek, M., 03.08.2023, In: NEURO-ONCOLOGY. 25, 8, p. 1518-1529 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1

    Oetting, A., Christiansen, S., Gatzemeier, F., Köcher, S., Bußmann, L., Böttcher, A., Stölzel, K., Hoffmann, A. S., Struve, N., Kriegs, M., Petersen, C., Betz, C., Rothkamm, K., Zech, H. B. & Rieckmann, T., 07.2023, In: CLIN TRANSL RAD ONCO. 41, p. 100630

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells

    Cetin, M. H., Rieckmann, T., Hoffer, K., Riepen, B., Christiansen, S., Gatzemeier, F., Feyerabend, S., Schoof, M., Schüller, U., Petersen, C., Mynarek, M., Rothkamm, K., Kriegs, M. & Struve, N., 29.01.2023, In: RADIAT ONCOL. 18, 1, 19.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. 2022

  10. Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas

    Goschzik, T., Mynarek, M., Doerner, E., Schenk, A., Spier, I., Warmuth-Metz, M., Bison, B., Obrecht, D., Struve, N., Kortmann, R-D., Schmid, M., Aretz, S., Rutkowski, S. & Pietsch, T., 12.2022, In: ACTA NEUROPATHOL. 144, 6, p. 1143-1156 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Increased replication stress and R-loop accumulation in EGFRvIII expressing glioblastoma present new therapeutic opportunities

    Struve, N., Hoffer, K., Weik, A-S., Riepen, B., Krug, L., Cetin, M. H., Burmester, J., Ott, L., Liebing, J., Gatzemeier, F., Müller-Goebel, J., Bußmann, L., Parplys, A. C., Unger, K., Mansour, W. Y., Schüller, U., Rieckmann, T., Petersen, C., Rothkamm, K., Short, S. C. & Kriegs, M., 12.03.2022, In: NEURO-ONCOL ADV. 4, 1, p. vdab180 vdab180.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. A Lack of Effectiveness in the ATM-Orchestrated DNA Damage Response Contributes to the DNA Repair Defect of HPV-Positive Head and Neck Cancer Cells

    Köcher, S., Zech, H. B., Krug, L., Gatzemeier, F., Christiansen, S., Meyer, F., Rietow, R., Struve, N., Mansour, W. Y., Kriegs, M., Petersen, C., Betz, C., Rothkamm, K. & Rieckmann, T., 2022, In: FRONT ONCOL. 12, 765968.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. 2021

  14. Analyzing tyrosine kinase activity in head and neck cancer by functional kinomics: Identification of hyperactivated Src-family kinases as prognostic markers and potential targets

    Bußmann, L., Hoffer, K., von Bargen, C. M., Droste, C., Lange, T., Kemmling, J., Schröder-Schwarz, J., Vu, A. T., Akingunsade, L., Nollau, P., Rangarajan, S., de Wijn, R., Oetting, A., Müller, C., Böckelmann, L. C., Zech, H. B., Berger, J. C., Möckelmann, N., Busch, C-J., Böttcher, A., Gatzemeier, F., Klinghammer, K., Simnica, D., Binder, M., Struve, N., Rieckmann, T., Schumacher, U., Clauditz, T. S., Betz, C. S., Petersen, C., Rothkamm, K., Münscher, A. & Kriegs, M., 01.09.2021, In: INT J CANCER. 149, 5, p. 1166 - 1180 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Dual Inhibition of PARP and the Intra-S/G2 Cell Cycle Checkpoints Results in Highly Effective Radiosensitization of HPV-Positive HNSCC Cells

    Hintelmann, K., Berenz, T., Kriegs, M., Christiansen, S., Gatzemeier, F., Struve, N., Petersen, C., Betz, C., Rothkamm, K., Oetting, A. & Rieckmann, T., 2021, In: FRONT ONCOL. 11, p. 683688

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. 2020

  17. Activation of Epidermal Growth Factor Receptor Sensitizes Glioblastoma Cells to Hypoxia-Induced Cell Death

    Luger, A-L., Lorenz, N. I., Urban, H., Divé, I., Engel, A. L., Strassheimer, F., Dettmer, K., Zeiner, P. S., Shaid, S., Struve, N., Kriegs, M., Hofmann, U., Oefner, P. J., Harter, P. N., Steinbach, J. P. & Ronellenfitsch, M. W., 03.08.2020, In: CANCERS. 12, 8

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. A novel workflow for three-dimensional analysis of tumour cell migration

    Ketchen, S., Rohwedder, A., Knipp, S., Esteves, F., Struve, N., Peckham, M., Ladbury, J. E., Curd, A., Short, S. C. & Brüning-Richardson, A., 06.04.2020, In: INTERFACE FOCUS. 10, 2, p. 20190070

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma

    Struve, N., Binder, Z. A., Stead, L. F., Brend, T., Bagley, S. J., Faulkner, C., Ott, L., Müller-Goebel, J., Weik, A-S., Hoffer, K., Krug, L., Rieckmann, T., Bußmann, L., Henze, M., Morrissette, J. J. D., Kurian, K. M., Schüller, U., Petersen, C., Rothkamm, K., O Rourke, D. M., Short, S. C. & Kriegs, M., 04.2020, In: ONCOGENE. 39, 15, p. 3041-3055 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. 2019

  21. Analyzing expression and phosphorylation of the EGF receptor in HNSCC

    Kriegs, M., Clauditz, T. S., Hoffer, K., Bartels, J., Buhs, S., Gerull, H., Zech, H. B., Bußmann, L., Struve, N., Rieckmann, T., Petersen, C., Betz, C. S., Rothkamm, K., Nollau, P. & Münscher, A., 19.09.2019, In: SCI REP-UK. 9, 1, p. 13564

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Characterization of the Effects of Migrastatic Inhibitors on 3D Tumor Spheroid Invasion by High-resolution Confocal Microscopy

    Harmer, J., Struve, N. & Brüning-Richardson, A., 16.09.2019, In: JOVE-J VIS EXP. 151

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. 2016

  24. Clustered localization of EGFRvIII in glioblastoma cells as detected by high precision localization microscopy

    Boyd, P. S., Struve, N., Bach, M., Eberle, J. P., Gote, M., Schock, F., Cremer, C., Kriegs, M. & Hausmann, M., 28.12.2016, In: NANOSCALE. 8, 48, p. 20037-20047

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines

    Riedel, M., Struve, N., Müller-Goebel, J., Köcher, S., Petersen, C., Dikomey, E., Rothkamm, K. & Kriegs, M., 20.09.2016, In: ONCOTARGET. 7, 38, p. 61988-61995

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests

    Kriegs, M., Kasten-Pisula, U., Riepen, B., Hoffer, K., Struve, N., Myllynen, L., Braig, F., Binder, M., Rieckmann, T., Grénman, R., Petersen, C., Dikomey, E. & Rothkamm, K., 19.07.2016, In: ONCOTARGET. 7, 29, p. 45122-45133

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. 2015

  28. EGFRvIII does not affect radiosensitivity with or without gefitinib treatment in glioblastoma cells

    Struve, N., Riedel, M., Schulte, A., Rieckmann, T., Grob, T. J., Gal, A., Rothkamm, K., Lamszus, K., Petersen, C., Dikomey, E. & Kriegs, M., 20.10.2015, In: ONCOTARGET. 6, 32, p. 33867-77 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review