Research ExplorerScientific StaffNicole Fischer Publications

Prof. Dr. ID: 53109

Nicole Fischer

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Publications

  1. 2020

  2. Merkel Cell Polyomavirus DNA Replication Induces Senescence in Human Dermal Fibroblasts in a Kap1/Trim28-Dependent Manner

    Siebels, S., Czech-Sioli, M., Spohn, M., Schmidt, C., Theiss, J., Indenbirken, D., Günther, T., Grundhoff, A. & Fischer, N., 10.03.2020, In: MBIO. 11, 2

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. The Ubiquitin specific Protease Usp7, a novel Merkel cell polyomavirus Large T-Antigen interaction partner, modulates viral DNA replication

    Czech-Sioli, M., Siebels, S., Radau, S., Zahedi, R. P., Schmidt, C., Dobner, T., Grundhoff, A. & Fischer, N., 14.02.2020, In: J VIROL. 94, 5

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. 2019

  5. DAMIAN an open source bioinformatics tool for fast, systematic and cohort based analysis of microorganisms in diagnostic samples

    Alawi, M., Burkhardt, L., Indenbirken, D., Reumann, K., Christopeit, M., Kröger, N., Lütgehetmann, M., Aepfelbacher, M., Fischer, N. & Grundhoff, A., 14.11.2019, In: SCI REP-UK. 9, 1, p. 16841

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Chronic equine hepacivirus infection in an adult gelding with severe hepatopathy

    Tegtmeyer, B., Echelmeyer, J., Pfankuche, V. M., Puff, C., Todt, D., Fischer, N., Durham, A., Feige, K., Baumgärtner, W., Steinmann, E. & Cavalleri, J-M. V., 08.2019, In: VET MED SCI. 5, 3, p. 372-378 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Detection and Characterization of Circulating Tumor Cells in Patients with Merkel Cell Carcinoma

    Riethdorf, S., Hildebrandt, L., Heinzerling, L., Heitzer, E., Fischer, N., Bergmann, S., Mauermann, O., Waldispühl-Geigl, J., Coith, C., Schön, G., Peine, S., Schuler, G., Speicher, M. R., Moll, I. & Pantel, K., 03.2019, In: CLIN CHEM. 65, 3, p. 462-472 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Changes in the composition of the upper respiratory tract microbial community in granulomatosis with polyangiitis

    Lamprecht, P., Fischer, N., Huang, J., Burkhardt, L., Lütgehetmann, M., Arndt, F., Rolfs, I., Kerstein, A., Iking-Konert, C. & Laudien, M., 02.2019, In: J AUTOIMMUN. 97, p. 29-39 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Piscine Orthoreovirus 3 Is Not the Causative Pathogen of Proliferative Darkening Syndrome (PDS) of Brown Trout ()

    Fux, R., Arndt, D., Langenmayer, M. C., Schwaiger, J., Ferling, H., Fischer, N., Indenbirken, D., Grundhoff, A., Dölken, L., Adamek, M., Steinhagen, D. & Sutter, G., 28.01.2019, In: VIRUSES-BASEL. 11, 2

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Further characterization of bovine hepacivirus: Antibody response, course of infection, and host tropism

    Baechlein, C., Baron, A. L., Meyer, D., Gorriz-Martin, L., Pfankuche, V. M., Baumgärtner, W., Polywka, S., Peine, S., Fischer, N., Rehage, J. & Becher, P., 01.2019, In: TRANSBOUND EMERG DIS. 66, 1, p. 195-206 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Identification of a novel clade of group A rotaviruses in fatally diseased domestic pigeons in Europe

    Rubbenstroth, D., Peus, E., Schramm, E., Kottmann, D., Bartels, H., McCowan, C., Schulze, C., Akimkin, V., Fischer, N., Wylezich, C., Hlinak, A., Spadinger, A., Großmann, E., Petersen, H., Grundhoff, A., Rautenschlein, S. & Teske, L., 01.2019, In: TRANSBOUND EMERG DIS. 66, 1, p. 552-561 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. 2018

  13. Generation of a novel next-generation sequencing-based method for the isolation of new human papillomavirus types

    Brancaccio, R. N., Robitaille, A., Dutta, S., Cuenin, C., Santare, D., Skenders, G., Leja, M., Fischer, N., Giuliano, A. R., Rollison, D. E., Grundhoff, A., Tommasino, M. & Gheit, T., 07.2018, In: VIROLOGY. 520, p. 1-10 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. HEV-positive blood donations represent a relevant infection risk for immunosuppressed recipients

    Westhölter, D., Hiller, J., Denzer, U., Polywka, S., Ayuk, F., Rybczynski, M., Horvatits, T., Gundlach, S., Blöcker, J., Schulze Zur Wiesch, J., Fischer, N., Addo, M. M., Peine, S., Göke, B., Lohse, A. W., Lütgehetmann, M. & Pischke, S., 07.2018, In: J HEPATOL. 69, 1, p. 36-42 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Novel Human Polyomavirus Noncoding Control Regions Differ in Bidirectional Gene Expression according to Host Cell, Large T-Antigen Expression, and Clinically Occurring Rearrangements

    Ajuh, E. T., Wu, Z., Kraus, E., Weissbach, F. H., Bethge, T., Gosert, R., Fischer, N. & Hirsch, H. H., 01.04.2018, In: J VIROL. 92, 7, p. e02231-17

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Epidemiology, biology and therapy of Merkel cell carcinoma:conclusions from the EU project IMMOMEC

    Becker, J. C., Stang, A., Hausen, A. Z., Fischer, N., DeCaprio, J. A., Tothill, R. W., Lyngaa, R., Hansen, U. K., Ritter, C., Nghiem, P., Bichakjian, C. K., Ugurel, S. & Schrama, D., 03.2018, In: CANCER IMMUNOL IMMUN. 67, 3, p. 341-351 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  17. Pathogenetic and Clinical Aspects of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitides

    Lamprecht, P., Kerstein, A., Klapa, S., Schinke, S., Karsten, C. M., Yu, X., Ehlers, M., Epplen, J. T., Holl-Ulrich, K., Wiech, T., Kalies, K., Lange, T., Laudien, M., Laskay, T., Gemoll, T., Schumacher, U., Ullrich, S., Busch, H., Ibrahim, S., Fischer, N., Hasselbacher, K., Pries, R., Petersen, F., Weppner, G., Manz, R., Humrich, J. Y., Nieberding, R., Riemekasten, G. & Müller, A., 2018, In: FRONT IMMUNOL. 9, p. 680

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  18. 2017

  19. High Abundance and Genetic Variability of Atypical Porcine Pestivirus in Pigs from Europe and Asia

    Postel, A., Meyer, D., Cagatay, G. N., Feliziani, F., De Mia, G. M., Fischer, N., Grundhoff, A., Milićević, V., Deng, M-C., Chang, C-Y., Qiu, H-J., Sun, Y., Wendt, M. & Becher, P., 12.2017, In: EMERG INFECT DIS. 23, 12, p. 2104-2107 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Complete Genome Sequence of a Novel Human Gammapapillomavirus Isolated from Skin

    Brancaccio, R. N., Robitaille, A., Dutta, S., Rollison, D. E., Fischer, N., Grundhoff, A., Tommasino, M. & Gheit, T., 24.08.2017, In: Genome Announc. 5, 34

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Spontaneous lung metastasis formation of human Merkel cell carcinoma cell lines transplanted into scid mice

    Knips, J., Czech-Sioli, M., Spohn, M., Heiland, M., Moll, I., Grundhoff, A., Schumacher, U. & Fischer, N., 01.07.2017, In: INT J CANCER. 141, 1, p. 160-171

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Recovery of the first full-length genome sequence of a parapoxvirus directly from a clinical sample

    Günther, T., Haas, L., Alawi, M., Wohlsein, P., Marks, J., Grundhoff, A., Becher, P. & Fischer, N., 16.06.2017, In: SCI REP-UK. 7, 1, p. 3734

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Successful retreatment of a patient with chronic hepatitis C genotype 2k/1b virus with ombitasvir/paritaprevir/ritonavir plus dasabuvir

    Todt, D., Schlevogt, B., Deterding, K., Grundhoff, A., Manns, M. P., Wedemeyer, H., Fischer, N., Cornberg, M. & Steinmann, E., 01.05.2017, In: J ANTIMICROB CHEMOTH. 72, 5, p. 1541-1543 3 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  24. Pregnancy-Related Immune Adaptation Promotes the Emergence of Highly Virulent H1N1 Influenza Virus Strains in Allogenically Pregnant Mice

    Engels, G., Hierweger, A. M., Hoffmann, J., Thieme, R., Thiele, S., Bertram, S., Dreier, C., Resa-Infante, P., Jacobsen, H., Thiele, K., Alawi, M., Indenbirken, D., Grundhoff, A., Siebels, S., Fischer, N., Stojanovska, V., Muzzio, D., Jensen, F., Karimi, K., Mittrücker, H-W., Arck, P. C. & Gabriel, G., 08.03.2017, In: CELL HOST MICROBE. 21, 3, p. 321-333 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Novel poly-uridine insertion in the 3'UTR and E2 amino acid substitutions in a low virulent classical swine fever virus

    Coronado, L., Liniger, M., Muñoz-González, S., Postel, A., Pérez, L. J., Pérez-Simó, M., Perera, C. L., Frías-Lepoureau, M. T., Rosell, R., Grundhoff, A., Indenbirken, D., Alawi, M., Fischer, N., Becher, P., Ruggli, N. & Ganges, L., 03.2017, In: VET MICROBIOL. 201, p. 103-112 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. 2016

  27. Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney

    Krebs, C. F., Paust, H-J., Krohn, S., Koyro, T., Brix, S. R., Riedel, J-H., Bartsch, P., Wiech, T., Meyer-Schwesinger, C., Huang, J., Fischer, N., Busch, C. P., Mittrücker, H-W., Steinhoff, U., Stockinger, B., Perez, L. G., Wenzel, U. O., Janneck, M., Steinmetz, O. M., Gagliani, N., Stahl, R. A. K., Huber, S., Turner, J-E. & Panzer, U., 15.11.2016, In: IMMUNITY. 45, 5, p. 1078-1092 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Replication of merkel cell polyomavirus induces reorganization of promyelocytic leukemia nuclear bodies

    Neumann, F., Czech-Sioli, M., Dobner, T., Grundhoff, A., Schreiner, S. & Fischer, N., 11.2016, In: J GEN VIROL. 97, 11, p. 2926-2938

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Multicenter quality assessment of 16S ribosomal DNA-sequencing for microbiome analyses reveals high inter-center variability

    Hiergeist, A., Reischl, U., Priority Program 1656 Intestinal Microbiota Consortium/ quality assessment participants & Gessner, A., 08.2016, In: INT J MED MICROBIOL. 306, 5, p. 334-42 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Suspected encephalitis with Candida tropicalis and Fusarium detected by unbiased RNA sequencing

    Christopeit, M., Grundhoff, A., Rohde, H., Belmar-Campos, C., Grzyska, U., Fiehler, J., Wolschke, C., Kröger, N-M. & Fischer, N., 29.07.2016, In: ANN HEMATOL. 95, 11, p. 1919-1921

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Pegivirus Infection in Domestic Pigs, Germany

    Baechlein, C., Grundhoff, A., Fischer, N., Alawi, M., Hoeltig, D., Waldmann, K-H. & Becher, P., 07.2016, In: EMERG INFECT DIS. 22, 7, p. 1312-4 3 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  32. Frequent presence of hepaci and pegiviruses in commercial equine serum pools

    Postel, A., Cavalleri, J-M. V., Pfaender, S., Walter, S., Steinmann, E., Fischer, N., Feige, K., Haas, L. & Becher, P., 15.01.2016, In: VET MICROBIOL. 182, p. 8-14 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Tropheryma whipplei in children with diarrhoea in rural Ghana

    Vinnemeier, C. D., Klupp, E. M., Krumkamp, R., Rolling, T., Fischer, N., Owusu-Dabo, E., Addo, M. M., Adu-Sarkodie, Y., Käsmaier, J., Aepfelbacher, M., Cramer, J. P., May, J. & Tannich, E., 08.01.2016, In: CLIN MICROBIOL INFEC. 22, 1, p. 65.e1 - 65.e3

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Investigation of Viral and Host Chromatin by ChIP-PCR or ChIP-Seq Analysis

    Günther, T., Theiss, J. M., Fischer, N. & Grundhoff, A., 2016, In: Curr Protoc Microbiol. 40, p. 1E.10.1-1E.10.21

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Presence of atypical porcine pestivirus (APPV) genomes in newborn piglets correlates with congenital tremor

    Postel, A., Hansmann, F., Baechlein, C., Fischer, N., Alawi, M., Grundhoff, A., Derking, S., Tenhündfeld, J., Pfankuche, V. M., Herder, V., Baumgärtner, W., Wendt, M. & Becher, P., 2016, In: SCI REP-UK. 6, p. 27735

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. 2015

  37. Merkel cell polyomavirus, a highly prevalent virus with tumorigenic potential

    Grundhoff, A. & Fischer, N., 05.10.2015, In: CURR OPIN VIROL. 14, p. 129-137 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence

    Theiss, J. M., Günther, T., Alawi, M., Neumann, F., Tessmer, U., Fischer, N. & Grundhoff, A., 07.2015, In: PLOS PATHOG. 11, 7, p. e1004974

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples

    Fischer, N., Indenbirken, D., Meyer, T., Lütgehetmann, M., Lellek, H., Spohn, M., Aepfelbacher, M., Alawi, M. & Grundhoff, A., 07.2015, In: J CLIN MICROBIOL. 53, 7, p. 2238-50 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Identification of a Novel Hepacivirus in Domestic Cattle from Germany

    Fischer, N., Baechlein, C., Grundhoff, A., Alawi, M., Indenbirken, D., Postel, A., Baron, A. L., Offinger, J., Becker, K., Beineke, A., Rehage, J. & Becher, P., 07.2015, In: J VIROL. 89, 14, p. 7007-15 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Highly divergent hepaciviruses from African cattle

    Corman, V. M., Grundhoff, A., Baechlein, C., Fischer, N., Gmyl, A., Wollny, R., Dei, D., Ritz, D., Binger, T., Adankwah, E., Marfo, K. S., Annison, L., Annan, A., Adu-Sarkodie, Y., Oppong, S., Becher, P., Drosten, C. & Drexler, J. F., 06.2015, In: J VIROL. 89, 11, p. 5876-82 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Close relationship of ruminant pestiviruses and classical Swine Fever virus

    Postel, A., Schmeiser, S., Oguzoglu, T. C., Indenbirken, D., Alawi, M., Fischer, N., Grundhoff, A. & Becher, P., 04.2015, In: EMERG INFECT DIS. 21, 4, p. 668-72 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. In Vitro Replication Assay for Merkel Cell Polyomavirus (MCPyV)

    Neumann, F., Czech-Sioli, M., Grundhoff, A. & Fischer, N., 2015, In: Curr Protoc Microbiol. 38, p. 14F.2.1-14F.2.19

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. 2014

  45. Complete Genome Sequence of Pronghorn Virus, a Pestivirus.

    Neill, J., Ridpath, J., Fischer, N., Grundhoff, A., Postel, A. & Becher, P., 12.06.2014, In: Genome Announc. 2, 3, p. e00575-14

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. Merkel Cell Polyomavirus

    Fischer, N. & Adam, G., 12.06.2014, Cancers in People with HIV and AIDS: Progress and Challenges. Yarchoan, R. (ed.). 1 ed. Springer, p. 113-122 10 p.

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research

  47. Rapid Metagenomic Diagnostics for Suspected Outbreak of Severe Pneumonia

    Fischer, N., Rohde, H., Indenbirken, D., Günther, T., Reumann, K., Lütgehetmann, M., Meyer, T., Kluge, S., Aepfelbacher, M., Alawi, M. & Grundhoff, A., 01.06.2014, In: EMERG INFECT DIS. 20, 6, p. 1072-5 4 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  48. High-affinity Rb Binding, p53 Inhibition, Subcellular Localization, and Transformation by Wild-Type or Tumor-Derived Shortened Merkel Cell Polyomavirus Large T Antigens

    Borchert, S., Czech-Sioli, M., Neumann, F., Schmidt, C., Wimmer, P., Dobner, T., Grundhoff, A. & Fischer, N., 01.03.2014, In: J VIROL. 88, 6, p. 3144-60 17 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. Complete Genome Sequence of Bovine Pestivirus Strain PG-2, a Second Member of the Tentative Pestivirus Species Giraffe

    Becher, P., Fischer, N., Grundhoff, A., Stalder, H., Schweizer, M. & Postel, A., 01.01.2014, In: Genome Announc. 2, 3

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. Merkel cell polyomavirus detection in Merkel cell cancer tumors in Northern Germany using PCR and protein expression

    Leitz, M., Stieler, K., Grundhoff, A., Moll, I., Brandner, J. M. & Fischer, N., 2014, In: J MED VIROL. 86 , 10, p. 1813-1819

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. Nachweis von Bakterien, Pilzen und Viren im Hochdurchsatz

    Fischer, N. & Grundhoff, A., 2014, In: BIOspektrum. 20, 5, p. 524-527 4 p., BIOspektrum 05.14.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  52. 2013

  53. Utilization of replication-competent XMRV reporter-viruses reveals severe viral restriction in primary human cells

    Stürzel, C. M., Palesch, D., Khalid, M., Wissing, S., Fischer, N. & Münch, J., 01.01.2013, In: PLOS ONE. 8, 9, p. e74427

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  54. 2012

  55. In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer.

    Lee, D., Jaydip, D. G., Gaughan, C., Steffen, I., Tang, N., Luk, K-C., Qiu, X., Urisman, A., Fischer, N., Molinaro, R., Broz, M., Schochetman, G., Klein, E. A., Ganem, D., Derisi, J. L., Simmons, G., Hackett, J., Silverman, R. H. & Chiu, C. Y., 2012, In: PLOS ONE. 7, 9, p. 44954 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  56. XMRV induces cell migration, cytokine expression and tumor angiogenesis: are 22Rv1 cells a suitable prostate cancer model?

    Stieler, K., Schumacher, U., Horst, A. & Fischer, N., 2012, In: PLOS ONE. 7, 7, p. 42321 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  57. 2011

  58. No detection of XMRV in blood samples and tissue sections from prostate cancer patients in Northern Europe.

    Stieler, K., Schindler, S., Schlomm, T., Hohn, O., Bannert, N., Simon, R., Minner, S. J. P., Schindler, M. & Fischer, N., 2011, In: PLOS ONE. 6, 10, p. 25592 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  59. Replication, gene expression and particle production by a consensus Merkel Cell Polyomavirus (MCPyV) genome.

    Neumann, F., Borchert, S., Schmidt, C., Reimer, R., Hohenberg, H., Fischer, N. & Grundhoff, A., 2011, In: PLOS ONE. 6, 12, p. 29112 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  60. S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection.

    Andresen, E., Lange, C., Strodthoff, D., Goldmann, T., Fischer, N., Sahly, H., Branscheid, D. & Heine, H., 2011, In: BMC PULM MED. 11, p. 10

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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