Research ExplorerScientific StaffKatharina Holstein Publications

Dr.med. ID: 52191

Katharina Holstein

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Publications

  1. 2023

  2. Emicizumab prophylaxis in patients with acquired haemophilia A (GTH-AHA-EMI): an open-label, single-arm, multicentre, phase 2 study

    Tiede, A., Hart, C., Knöbl, P., Greil, R., Oldenburg, J., Sachs, U. J., Miesbach, W., Pfrepper, C., Trautmann-Grill, K., Holstein, K., Pilch, J., Möhnle, P., Schindler, C., Weigt, C., Schipp, D., May, M., Dobbelstein, C., Pelzer, F. J., Werwitzke, S. & Klamroth, R., 11.2023, In: LANCET HAEMATOL. 10, 11, p. e913-e921

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Expression and Release of Tumor Cell Tissue Factor Triggers Recurrent Thromboembolism in a Patient with Endometrial Cancer

    Beckmann, L., Lennartz, M., Poch, A., Holstein, K., Bokemeyer, C. & Langer, F., 08.2023, In: HAMOSTASEOLOGIE. 43, 4, p. 289-296 8 p.

    Research output: SCORING: Contribution to journal › Case report › Research › peer-review

  4. Gentherapie der Hämophilie: Empfehlung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH)

    Miesbach, W., Oldenburg, J., Klamroth, R., Eichler, H., Koscielny, J., Holzhauer, S., Holstein, K., Hovinga, J. A. K., Alberio, L., Olivieri, M., Knöfler, R., Male, C. & Tiede, A., 06.2023, In: HAMOSTASEOLOGIE. 43, 3, p. 196-207 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. Synovitis and joint health in patients with haemophilia: Statements from a European e-Delphi consensus study

    Mancuso, M. E., Holstein, K., O'Donnell, J. S., Lobet, S., Klamroth, R. & FVIII Think Tank Study Group, 03.2023, In: HAEMOPHILIA. 29, 2, p. 619-628 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Targets of autoantibodies in acquired hemophilia A are not restricted to factor VIII: data from the GTH-AH 01/2010 study

    Oleshko, O., Werwitzke, S., Klingberg, A., Witte, T., Eichler, H., Klamroth, R., Holstein, K., Hart, C., Pfrepper, C., Knöbl, P., Greil, R., Neumeister, P., Reipert, B. M. & Tiede, A., 10.01.2023, In: BLOOD ADV. 7, 1, p. 122-130 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. 2022

  8. Erratum: Gentherapie der Hämophilie: Empfehlung der Gesellschaft für Thrombose- und Hämostaseforschung (GTH)

    Miesbach, W., Oldenburg, J., Klamroth, R., Eichler, H., Koscielny, J., Holzhauer, S., Holstein, K., Hovinga, J. A. K., Alberio, L., Olivieri, M., Knöfler, R., Male, C. & Tiede, A., 21.12.2022, In: HAMOSTASEOLOGIE.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  9. Evaluation of different diagnostic tools for detection of acquired von Willebrand syndrome in patients with polycythemia vera or essential thrombocythemia

    Janjetovic, S., Rolling, C. C., Budde, U., Schneppenhem, S., Schafhausen, P., Peters, M. C., Bokemeyer, C., Holstein, K. & Langer, F., 10.2022, In: THROMB RES. 218, p. 35-43 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Safety of intramuscular COVID-19 vaccination in patients with haemophilia

    Tiede, A., Leise, H., Horneff, S., Oldenburg, J., Halimeh, S., Heller, C., Königs, C., Holstein, K. & Pfrepper, C., 09.2022, In: HAEMOPHILIA. 28, 5, p. 687-693 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Sixth Åland Island Conference on von Willebrand disease

    Berntorp, E., Trakymienė, S. S., Federici, A. B., Holstein, K., Corrales-Medina, F. F., Pierce, G. F., Srivastava, A., Prondzinski, M. V. D., Johnsen, J. M., Zupan, I. P., Halimeh, S., Nummi, V. & Roberts, J. C., 07.2022, In: HAEMOPHILIA. 28, Suppl 5, p. 3-15 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Quality of life in a large multinational haemophilia B cohort (The B-Natural study) - Unmet needs remain

    Berntorp, E., LeBeau, P., Ragni, M. V., Borhany, M., Abajas, Y. L., Tarantino, M. D., Holstein, K., Croteau, S. E., Liesner, R., Tarango, C., Carvalho, M., McGuinn, C., Funding, E., Kempton, C. L., Bidlingmaier, C., Cohen, A., Oldenburg, J., Kearney, S., Knoll, C., Kuriakose, P., Acharya, S., Reiss, U. M., Kulkarni, R., Witkop, M., Lethagen, S., Krouse, R., Shapiro, A. D. & Astermark, J., 05.2022, In: HAEMOPHILIA. 28, 3, p. 453-461 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. The Bone Microarchitecture Deficit in Patients with Hemophilia Is Influenced by Arthropathy, Hepatitis C Infection, and Physical Activity

    Holstein, K., Witt, L., Matysiak, A., Schmidt, C., Barvencik, F., Amling, M., Rolvien, T. & Langer, F., 05.2022, In: THROMB HAEMOSTASIS. 122, 5, p. 692-702 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Purpura Fulminans Triggered by the Formation of Anti-Endothelial Autoantibodies in a Patient with Chronic Lymphocytic Leukemia

    Beckmann, L., Lennartz, M., Beitzen-Heineke, A., Voigtländer, M., Rolling, C., Holstein, K., Bokemeyer, C., Amirkhosravi, A. & Langer, F., 17.03.2022, In: Ann Hematol Oncol. 9, 1, 1389.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Electronic diaries in the management of haemophilia gene therapy: Perspective of an expert group from the German, Austrian and Swiss Society on Thrombosis and Haemostasis (GTH)

    Miesbach, W., Eichler, H., Holstein, K., Holzhauer, S., Klamroth, R., Knöfler, R., Male, C., Olivieri, M., Oldenburg, J. & Tiede, A., 03.2022, In: HAEMOPHILIA. 28, 2, p. 264-269 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Immune tolerance induction in the era of emicizumab - still the first choice for patients with haemophilia A and inhibitors?

    Holstein, K., Le Quellec, S., Klamroth, R., Batorova, A., Holme, P. A., Jiménez-Yuste, V. & Astermark, J., 03.2022, In: HAEMOPHILIA. 28, 2, p. 215-222 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Hämophilie im Alter: Herausforderungen der Therapie

    Holstein, K., 2022, In: Kompendium ... Hämatologie/Onkologie. 2022, p. 67-72 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research

  18. 2021

  19. Clinical and patient reported outcome in total ankle replacement compared to ankle fusion in end-stage haemophilic arthropathy

    Mussawy, H., Kehrer, M., Strahl, A., Rolvien, T., Hubert, J., Beil, F. T., Wirtz, D. C., Oldenburg, J., Holstein, K. & Strauss, A. C., 11.2021, In: HAEMOPHILIA. 27, 6, p. e739-e746

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. The B-Natural study-The outcome of immune tolerance induction therapy in patients with severe haemophilia B

    Astermark, J., Holstein, K., Abajas, Y. L., Kearney, S., Croteau, S. E., Liesner, R., Funding, E., Kempton, C. L., Acharya, S., Lethagen, S., LeBeau, P., Bowen, J., Berntorp, E. & Shapiro, A. D., 09.2021, In: HAEMOPHILIA. 27, 5, p. 802-813 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Monocyte activation and acquired autoimmune protein S deficiency promote disseminated intravascular coagulation in a patient with primary antiphospholipid syndrome

    Beckmann, L., Voigtländer, M., Holstein, K., Lennartz, M., Schneider, S. W., Haddad, M., Renné, T., Bokemeyer, C., Rolling, C. C. & Langer, F., 07.2021, In: RES PRACT THROMB HAE. 5, 5, e12559.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Consensus Recommendations for Intramuscular COVID-19 Vaccination in Patients with Hemophilia

    Pfrepper, C., Holstein, K., Königs, C., Heller, C., Krause, M., Olivieri, M., Bidlingmaier, C., Sigl-Kraetzig, M., Wendisch, J., Halimeh, S., Horneff, S., Richter, H., Wieland, I., Klamroth, R., Oldenburg, J., Tiede, A. & Hemophilia Board of the German, Austrian, Swiss Society on Thrombosis Hemostasis Research (GTH), 06.2021, In: HAMOSTASEOLOGIE. 41, 3, p. 190-196 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Auswirkungen der COVID-19 Pandemie auf die medizinische Versorgung von Patienten mit angeborenen Blutungsneigungen

    Olivieri, M., Halimeh, S., Wermes, C., Hassenpflug, W., Holstein, K. & von Mackensen, S., 04.2021, In: GESUNDHEITSWESEN. 83, 4, p. 282-290 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Prevalence of definite antiphospholipid syndrome in carriers of the JAK2V617F mutation

    Janjetovic, S., Beckmann, L., Holstein, K., Rolling, C., Thiele, B., Schafhausen, P., Schön, G., Bokemeyer, C., Langer, F. & Voigtlaender, M., 02.2021, In: THROMB RES. 198, p. 55-61 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Natural history study of factor IX deficiency with focus on treatment and complications (B-Natural)

    Shapiro, A. D., Ragni, M. V., Borhany, M., Abajas, Y. L., Tarantino, M. D., Holstein, K., Croteau, S. E., Liesner, R., Tarango, C., Carvalho, M., McGuinn, C., Funding, E., Kempton, C. L., Bidlingmaier, C., Cohen, A., Oldenburg, J., Kearney, S., Knoll, C., Kuriakose, P., Acharya, S., Reiss, U. M., Kulkarni, R., Witkop, M., Lethagen, S., Donfield, S., LeBeau, P., Berntorp, E. & Astermark, J., 01.2021, In: HAEMOPHILIA. 27, 1, p. 49-59 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. 2020

  27. Practical Guidance of the GTH Haemophilia Board on the Use of Emicizumab in Patients with Haemophilia A

    Holstein, K., Albisetti, M., Bidlingmaier, C., Halimeh, S., Heine, S., Klamroth, R., Königs, C., Kurnik, K., Male, C., Oldenburg, J., Streif, W., Wermes, C., Escuriola-Ettingshausen, C. & ‘Ständige Kommission Hämophilie’ (Haemophilia board) of the German, Swiss Austrian Society for Thrombosis Haemostasis Research (GTH), 12.2020, In: HAMOSTASEOLOGIE. 40, 5, p. 561-571 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  28. Impact of COVID-19 pandemic on mental health of patients with inherited bleeding disorders in Germany

    von Mackensen, S., Halimeh, S., Siebert, M., Wermes, C., Hassenpflug, W., Holstein, K. & Olivieri, M., 11.2020, In: HAEMOPHILIA. 26, 6, p. e272-e281

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Comparison of acetylsalicylic acid and clopidogrel non-responsiveness assessed by light transmittance aggregometry and PFA-100® in patients undergoing neuroendovascular procedures

    Rolling, C. C., Tomada, J., Frölich, A. M., Holst, B., Holstein, K., Voigtländer, M., Janjetovic, S., Haddad, M., Renné, T., Fiehler, J., Bokemeyer, C., Rolling, T. & Langer, F., 31.08.2020, In: CLIN CHEM LAB MED. 59, 2, p. 383-392 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Bleeding and response to hemostatic therapy in acquired hemophilia A: results from the GTH-AH 01/2010 study

    Holstein, K., Liu, X., Smith, A., Knöbl, P., Klamroth, R., Geisen, U., Eichler, H., Miesbach, W. & Tiede, A., 16.07.2020, In: BLOOD. 136, 3, p. 279-287 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. LPS-induced expression and release of monocyte tissue factor in patients with haemophilia

    Holstein, K., Matysiak, A., Witt, L., Sievers, B., Beckmann, L., Haddad, M., Renné, T., Voigtländer, M. & Langer, F., 07.2020, In: ANN HEMATOL. 99, 7, p. 1531-1542 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Cross-reacting inhibitors against recombinant porcine factor VIII in acquired hemophilia A: Data from the GTH-AH 01/2010 Study

    Türkantoz, H., Königs, C., Knöbl, P., Klamroth, R., Holstein, K., Huth-Kühne, A., Heinz, J., Eichler, H. & Tiede, A., 01.2020, In: J THROMB HAEMOST. 18, 1, p. 36-43 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. 2019

  34. Smart Medication ™, an Electronic Diary for Surveillance of Haemophilia Home Care and Optimization of Resource Distribution

    Mondorf, W., Eichler, H., Fischer, R., Holstein, K., Klamroth, R., Nimtz-Talaska, A., Wermes, C., Richter, H. & Severin, K., 11.2019, In: HAMOSTASEOLOGIE. 39, 4, p. 339-346 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Apixaban for the Treatment of Chronic Disseminated Intravascular Coagulation: A Report of Two Cases

    Janjetovic, S., Holstein, K., Dicke, C., Bokemeyer, C. & Langer, F., 08.2019, In: HAMOSTASEOLOGIE. 39, 3, p. 294-297 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. Niedermolekulare Heparine in der Onkologie: Überblick und Indikationen

    Holstein, K., 05.2019, In: Vasomed. 2019, 3

    Research output: SCORING: Contribution to journal › Conference article in journal › Education

  37. 2018

  38. The impact of bleeding disorders on the socioeconomic status of adult patients. Results of a comparative single centre cohort study

    Holstein, K., von Mackensen, S., Bokemeyer, C. & Langer, F., 10.08.2018, In: HAMOSTASEOLOGIE. 38, 3, p. 150-157 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Joint disease in haemophilia: Pathophysiology, pain and imaging

    van Vulpen, L. F. D., Holstein, K. & Martinoli, C., 05.2018, In: HAEMOPHILIA. 24, SI 6, p. 44-49 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  40. 2016

  41. Current view and outcome of ITI therapy - A change over time?

    Holstein, K., Batorova, A., Carvalho, M., Fijnvandraat, K., Holme, P., Kavakli, K., Lambert, T., Rocino, A., Jiménez-Yuste, V., Astermark, J. & European Haemophilia Therapy Strategy Board (EHTSB), 12.2016, In: THROMB RES. 148, p. 38-44 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Expression and release of platelet protein disulphide isomerase in patients with haemophilia A

    Voigtländer, M., Holstein, K., Spath, B., Bokemeyer, C. & Langer, F., 11.2016, In: HAEMOPHILIA. 22, 6, p. e537-e544

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Anti-factor VIII IgA as a potential marker of poor prognosis in acquired hemophilia A: results from the GTH-AH 01/2010 study

    Tiede, A., Hofbauer, C. J., Werwitzke, S., Knöbl, P., Gottstein, S., Scharf, R. E., Heinz, J., Groß, H-J., Holstein, K., Dobbelstein, C., Scheiflinger, F., Koch, A. & Reipert, B. M., 12.05.2016, In: BLOOD. 127, 19, p. 2289-97 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Diagnostic and prognostic value of factor VIII binding antibodies in acquired hemophilia A: data from the GTH-AH 01/2010 study

    Werwitzke, S., Geisen, U., Nowak-Göttl, U., Eichler, H., Stephan, B., Scholz, U., Holstein, K., Klamroth, R., Knöbl, P. N., Huth-Kühne, A., Bomke, B. & Tiede, A., 05.2016, In: J THROMB HAEMOST. 14, 5, p. 940-7 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Distinct mechanisms account for acquired von Willebrand syndrome in plasma cell dyscrasias

    Dicke, C., Schneppenheim, S., Holstein, K., Spath, B., Bokemeyer, C., Dittmer, R., Budde, U. & Langer, F., 05.2016, In: ANN HEMATOL. 95, 6, p. 945-57 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. The impact of social factors on outcomes in patients with bleeding disorders

    Holstein, K., von Mackensen, S., Bokemeyer, C. & Langer, F., 01.2016, In: HAEMOPHILIA. 22, 1, p. 46-53

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. 2015

  48. Novel, human cell line-derived recombinant factor VIII (human-cl rhFVIII; Nuwiq(®) ) in adults with severe haemophilia A: efficacy and safety

    Lissitchkov, T., Hampton, K., von Depka, M., Hay, C., Rangarajan, S., Tuddenham, E., Holstein, K., Huth-Kühne, A., Pabinger, I., Knaub, S., Bichler, J. & Oldenburg, J., 28.08.2015, In: HAEMOPHILIA.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. Prognostic factors for remission of and survival in acquired hemophilia A (AHA): results from the GTH-AH 01/2010 study

    Tiede, A., Klamroth, R., Scharf, R. E., Trappe, R. U., Holstein, K., Huth-Kühne, A., Gottstein, S., Geisen, U., Schenk, J., Scholz, U., Schilling, K., Neumeister, P., Miesbach, W., Manner, D., Greil, R., von Auer, C., Krause, M., Leimkühler, K., Kalus, U., Blumtritt, J-M., Werwitzke, S., Budde, E., Koch, A. & Knöbl, P., 12.02.2015, In: BLOOD. 125, 7, p. 1091-7 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. Atypical venous thromboses in myeloproliferative neoplasias

    Dicke, C., Frölich, A., Holstein, K., Bokemeyer, C. & Langer, F., 2015, In: PHLEBOLOGIE. 44, 6, p. 324–329

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. Clinical Evidence that Coagulation Activation Drives Cancer Progression - a Report of 2 Cases

    Voigtländer, M., Holstein, K., Leuenroth, S., Mudter, J., Bokemeyer, C. & Langer, F., 2015, In: ONCOL RES TREAT. 38, 9, p. 449-52 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. Thrombin generation in a patient with an acquired high-titre factor V inhibitor

    Schmidt, D. E., Steinhagen, F., Schnabel, C., Spath, B., Holstein, K., Fiedler, W., Bokemeyer, C., Renné, T. & Langer, F., 2015, In: BLOOD COAGUL FIBRIN. 26, 1, p. 81-87

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. 2014

  54. Seltene Gerinnungsstörung oder ein Fall für den Psychiater

    Zinser, M., Holstein, K., Langer, F., Voigt, P-U. & Holzhüter, J., 20.11.2014, In: Hamb Ärztebl. 2014, 11, p. 30-31

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Transfer

  55. Acquired hemophilia A and von Willebrand syndrome in a patient with late-onset systemic lupus erythematosus

    Dicke, C., Holstein, K., Schneppenheim, S., Dittmer, R., Schneppenheim, R., Bokemeyer, C., Iking-Konert, C., Budde, U. & Langer, F., 20.08.2014, In: EXP HEMATOL ONCOL. 3, p. 21

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  56. Relationship between haemophilia and social status

    Holstein, K., Eifrig, B. & Langer, F., 09.04.2014, In: THROMB RES.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research

  57. Characterisation of the p.A1461D mutation causing von Willebrand disease type 2B with severe thrombocytopenia, circulating giant platelets, and defective α-granule secretion

    Langer, F., Obser, T., Oyen, F., Spath, B., Holstein, K., Greinacher, A., White, J. G., Budde, U., Bokemeyer, C. & Schneppenheim, R., 01.04.2014, In: THROMB HAEMOSTASIS. 111, 4, p. 777-779 3 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  58. Successful second ITI with factor IX and combined immunosuppressive therapy. A patient with severe haemophilia B and recurrence of a factor IX inhibitor

    Holstein, K., Schneppenheim, R., Schrum, J., Bokemeyer, C. & Langer, F., 01.01.2014, In: HAMOSTASEOLOGIE. 34 , 4A, p. 5-8

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  59. 2013

  60. Relevant bleeding diathesis due to acquired factor XIII deficiency

    Janning, M., Holstein, K., Spath, B., Schnabel, C., Bannas, P., Bokemeyer, C. & Langer, F., 01.01.2013, In: HAMOSTASEOLOGIE. 33 Suppl 1, p. S50-4

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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