Center for Diagnostics

Publications

  1. 2022
  2. Epigenetic profiling reveals a subset of pediatric-type glioneuronal tumors characterized by oncogenic gene fusions involving several targetable kinases

    Sievers, P., Sill, M., Schrimpf, D., Friedel, D., Sturm, D., Gardberg, M., Kurian, K. M., Krskova, L., Vicha, A., Schaller, T., Hagel, C., Abdullaev, Z., Aldape, K., Jacques, T. S., Korshunov, A., Wick, W., Pfister, S. M., von Deimling, A., Jones, D. T. W. & Sahm, F., 11.2022, In: ACTA NEUROPATHOL. 144, 5, p. 1049-1052 4 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  3. Evidence of beta amyloid independent small vessel disease in familial Alzheimer's disease

    Littau, J. L., Velilla, L., Hase, Y., Villalba-Moreno, N. D., Hagel, C., Drexler, D., Osorio Restrepo, S., Villegas, A., Lopera, F., Vargas, S., Glatzel, M., Krasemann, S., Quiroz, Y. T., Arboleda-Velasquez, J. F., Kalaria, R. & Sepulveda-Falla, D., 11.2022, In: BRAIN PATHOL. 32, 6, p. e13097

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Genetic and epigenetic profiling identifies two distinct classes of spinal meningiomas

    Ricklefs, F. L., Fita, K., Mohme, M., Mawrin, C., Rahmanzade, R., Sahm, F., Dührsen, L., Göbel, C., Lamszus, K., Westphal, M., Schüller, U. & Eicker, S-O., 11.2022, In: ACTA NEUROPATHOL. 144, 5, p. 1057-1059 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  5. Humoral and Cellular Immune Response After Third and Fourth SARS-CoV-2 mRNA Vaccination in Liver Transplant Recipients

    Harberts, A., Schaub, G. M., Ruether, D. F., Duengelhoef, P. M., Brehm, T. T., Karsten, H., Fathi, A., Jahnke-Triankowski, J., Fischer, L., Addo, M., Haag, F., Lütgehetmann, M., Lohse, A. W., Schulze zur Wiesch, J. & Sterneck, M., 11.2022, In: CLIN GASTROENTEROL H. 20, 11, p. 2558-2566.e5

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. In memory of Prof Werner Janssen, Hamburg (Germany)

    Ondruschka, B. & Püschel, K., 11.2022, In: LEGAL MED-TOKYO. 59, p. 102114 102114.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  7. Merkel cell carcinoma and immune evasion: Merkel cell polyomavirus small T-antigen induced surface changes can be reverted by therapeutic intervention

    Schlemeyer, T., Ohnezeit, D., Virdi, S., Körner, C., Weißelberg, S., Starzonek, S., Schumacher, U., Grundhoff, A., Indenbirken, D., Albertini, S. & Fischer, N., 11.2022, In: J INVEST DERMATOL. 142, 11, p. 3071-3081.e13

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. P2X7 is expressed on human innate-like T lymphocytes and mediates susceptibility to ATP-induced cell death

    Winzer, R., Serracant-Prat, A., Brock, V. J., Pinto-Espinoza, C., Rissiek, B., Amadi, M., Eich, N., Rissiek, A., Schneider, E., Magnus, T., Guse, A. H., Diercks, B-P., Koch-Nolte, F. & Tolosa, E., 11.2022, In: EUR J IMMUNOL. 52, 11, p. 1805-1818 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. The hepatitis delta virus and chronic hepatitis D

    Dandri, M., Volmari, A. & Lütgehetmann, M., 11.2022, In: J HEPATOL. 77, 5, p. 1448-1450 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  10. The histopathological synovitis score is influenced by biopsy location in patients with knee osteoarthritis

    Mussawy, H., Zustin, J., Luebke, A. M., Strahl, A., Krenn, V., Rüther, W. & Rolvien, T., 11.2022, In: ARCH ORTHOP TRAUM SU. 142, 11, p. 2991-2997 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Tissue-resident memory T cells in the kidney

    Asada, N., Ginsberg, P., Gagliani, N., Mittrücker, H-W. & Panzer, U., 11.2022, In: SEMIN IMMUNOPATHOL. 44, 6, p. 801-811 11 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  12. Tuft cell-like carcinomas: novel cancer subsets present in multiple organs sharing a unique gene expression signature

    Yamada, Y., Bohnenberger, H., Kriegsmann, M., Kriegsmann, K., Sinn, P., Goto, N., Nakanishi, Y., Seno, H., Chigusa, Y., Fujimoto, M., Minamiguchi, S., Haga, H., Simon, R., Sauter, G., Ströbel, P. & Marx, A., 11.2022, In: BRIT J CANCER. 127, 10, p. 1876-1885 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. 17th German Spine Congress, Annual Meeting of the German Spine Society: The three-dimensional bone microstructure of the axis and clinical implications

    Köpke, L-G., von Kroge, S., Heuer, A., Kammal, M., Ondruschka, B., Rolvien, T. & Viezens, L., 28.10.2022, In: EUR SPINE J. 31, 11, p. 3240-3240 1 p., P099.

    Research output: SCORING: Contribution to journalConference abstract in journalResearchpeer-review

  14. Novel diagnostic fast track using aspiration cytology in malignant spinal lesions – a multidisciplinary approach

    Heuer, A., Köpke, L-G., Strahl, A., Stangenberg, M., Dreimann, M., Welker, L., Bokemeyer, C., Asemissen, A. M. & Viezens, L., 25.10.2022, In: Ger Med Sci. 2022

    Research output: SCORING: Contribution to journalConference abstract in journalResearchpeer-review

  15. Screening for Monkeypox Infection in Asymptomatic High-Risk-Behaviour Men Having Sex with Men (MSM)

    Pestel, J., Matthews, H., Schmiedel, S., Hüfner, A., Jordan, S., Scheiter, R. L., Lütgehetmann, M., Nörz, D. & Degen, O., 17.10.2022, In: INFECT DIS REP. 14, 5, p. 794-797 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions

    Wilmes, M., Pinto Espinoza, C., Ludewig, P., Stabernack, J., Liesz, A., Nicke, A., Gelderblom, M., Gerloff, C., Falzoni, S., Tolosa, E., Di Virgilio, F., Rissiek, B., Plesnilla, N., Koch-Nolte, F. & Magnus, T., 12.10.2022, In: J NEUROINFLAMM. 19, 1, 256.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Correction to An Integrated Strategy Reveals Complex Glycosylation of Erythropoietin Using Mass Spectrometry

    Guan, Y., Zhang, M., Gaikwad, M., Voss, H., Fazel, R., Ansari, S., Shen, H., Wang, J. & Schlüter, H., 07.10.2022, In: J PROTEOME RES. 21, 10, 2552.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  18. Inhibin Alpha Expression in Human Tumors: A Tissue Microarray Study on 12,212 Tumors

    Weidemann, S., Noori, N. A., Lennartz, M., Reiswich, V., Dum, D., Menz, A., Chirico, V., Hube-Magg, C., Fraune, C., Bawahab, A. A., Bernreuther, C., Simon, R., Clauditz, T. S., Sauter, G., Hinsch, A., Kind, S., Jacobsen, F., Steurer, S., Minner, S., Burandt, E., Marx, A. H., Krech, T., Lebok, P., Büscheck, F. & Höflmayer, D., 07.10.2022, In: BIOMEDICINES. 10, 10, 2507.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Predictors of Loneliness among Homeless Individuals in Germany during the COVID-19 Pandemic

    Dost, K., Heinrich, F., Graf, W., Brennecke, A., Kowalski, V., Leider, A., Kraus, A., van Rüth, V., Ondruschka, B., Püschel, K., König, H-H., Bertram, F. & Hajek, A., 05.10.2022, In: INT J ENV RES PUB HE. 19, 19, 12718.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Comprehensive profiling of myxopapillary ependymomas identifies a distinct molecular subtype with relapsing disease

    Bockmayr, M., Harnisch, K., Pohl, L. C., Schweizer, L., Mohme, T., Körner, M., Alawi, M., Suwala, A. K., Dorostkar, M. M., Monoranu, C. M., Hasselblatt, M., Wefers, A. K., Capper, D., Hench, J., Frank, S., Richardson, T. E., Tran, I., Liu, E., Snuderl, M., Engertsberger, L., Benesch, M., von Deimling, A., Obrecht, D., Mynarek, M., Rutkowski, S., Glatzel, M., Neumann, J. E. & Schüller, U., 03.10.2022, In: NEURO-ONCOLOGY. 24, 10, p. 1689-1699 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. 17th German Spine Congress, Annual Meeting of the German Spine Society: Shortening the time to diagnosis and therapy in spinal lesions of unknown malignancy

    Köpke, L-G., Heuer, A., Schmidt, G., Strahl, A., Stangenberg, M., Dreimann, M., Welker, L., Bokemeyer, C., Asemissen, A. M. & Viezens, L., 10.2022, In: EUR SPINE J. 31, 11, p. 3187-3187 1 p., V51.

    Research output: SCORING: Contribution to journalConference abstract in journalResearchpeer-review

  22. Clinical characteristics and comparison of longitudinal qPCR results from different specimen types in a cohort of ambulatory and hospitalized patients infected with monkeypox virus

    Nörz, D., Brehm, T. T., Tang, H. T., Grewe, I., Hermanussen, L., Matthews, H., Pestel, J., Degen, O., Günther, T., Grundhoff, A., Fischer, N., Addo, M. M., Jordan, S., Hertling, S., Unger, S., Schäfer, G., Schewe, K., Hoffmann, C., Aepfelbacher, M., Pfefferle, S., Schulze Zur Wiesch, J., Schmiedel, S. & Lütgehetmann, M., 10.2022, In: J CLIN VIROL. 155, 105254.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Clinical efficacy and in vitro neutralization capacity of monoclonal antibodies for severe acute respiratory syndrome coronavirus 2 delta and omicron variants

    Brehm, T. T., Pfefferle, S., von Possel, R., Karolyi, M., Zoufaly, A., Wichmann, D., Kobbe, R., Emmerich, P., Nörz, D., Aepfelbacher, M., Schulze Zur Wiesch, J., Addo, M. M., Schmiedel, S. & Lütgehetmann, M., 10.2022, In: J MED VIROL. 94, 10, p. 5038-5043 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Human dental pulp cells modulate CD8+ T cell proliferation and efficiently degrade extracellular ATP to adenosine in vitro

    Ahmadi, P., Yan, M., Bauche, A., Smeets, R., Müller, C. E., Koch-Nolte, F., Haag, F., Fliegert, R., Kluwe, L., Schulze Zur Wiesch, J. & Hartjen, P., 10.2022, In: CELL IMMUNOL. 380, 104589.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Netrin G1 is a Novel Target Antigen in Primary Membranous Nephropathy

    Reinhard, L., Machalitza, M., Wiech, T., Groene, H-J., Lassé, M., Rinschen, M., Ferru, N., Bräsen, J., Drömann, F., Rob, P., Sethi, S., Hoxha, E. & Stahl, R., 10.2022, In: J AM SOC NEPHROL. 33, 10, p. 1823-1831 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Regulation of Liprin-α phase separation by CASK is disrupted by a mutation in its CaM kinase domain

    Tibbe, D., Ferle, P., Krisp, C., Nampoothiri, S., Mirzaa, G., Assaf, M., Parikh, S., Kutsche, K. & Kreienkamp, H-J., 10.2022, In: LIFE SCI ALLIANCE. 5, 10, e202201512.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Sacrospinous and sacrotuberous ligaments influence in pelvis kinematics

    Henyš, P., Ramezani, M., Schewitz, D., Höch, A., Möbius, D., Ondruschka, B. & Hammer, N., 10.2022, In: J ANAT. 241, 4, p. 928-937 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Staphylococcus epidermidis-Derived Protease Esp Mediates Proteolytic Activation of Pro‒IL-1β in Human Keratinocytes

    Rademacher, F., Bartels, J., Gläser, R., Rodewald, M., Schubert, S., Drücke, D., Rohde, H. & Harder, J., 10.2022, In: J INVEST DERMATOL. 142, 10, p. 2756-2765.e8

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Thromboembolic events in deceased patients with proven SARS-CoV-2 infection: Frequency, characteristics and risk factors

    Voigtlaender, M., Edler, C., Gerling, M., Schädler, J., Ondruschka, B., Schröder, A. S., Sperhake, J., Ehrhardt, S., Wang, L., Haddad, M., Kiencke, V., Renné, T., Roedl, K., Kluge, S., Wichmann, D. & Langer, F., 10.2022, In: THROMB RES. 218, p. 171-176 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Unexpected spotlight on two unusual substances

    Zwirner, J., Dressler, J., Gradistanac, T., Möbius, D., Edler, C. & Ondruschka, B., 10.2022, In: RECHTSMEDIZIN. 32, p. 401–406 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Visualization of the distal tibial plafond articular surface using four established approaches and the efficacy of instrumented distraction: a cadaveric study.

    Kleinertz, H., Tessarzyk, M., Schoof, B., Nüchtern, J. V., Püschel, K., Barg, A. & Frosch, KH., 10.2022, In: EUR J TRAUMA EMERG S. 48, 5, p. 4031-4041 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Four-wheel-drive immune protection

    Heinrich, F. & Krasemann, S., 27.09.2022, In: SIGNAL TRANSDUCT TAR. 7, 1, p. 337

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  33. Loss of Homeostatic Microglia Signature in Prion Diseases

    Wang, Y., Hartmann, K., Thies, E., Mohammadi, B., Altmeppen, H., Sepulveda-Falla, D., Glatzel, M. & Krasemann, S., 21.09.2022, In: CELLS-BASEL. 11, 19, 2948.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  34. Remdesivir-induced emergence of SARS-CoV2 variants in patients with prolonged infection

    Heyer, A., Günther, T., Robitaille, A., Lütgehetmann, M., Addo, M. M., Jarczak, D., Kluge, S., Aepfelbacher, M., Schulze Zur Wiesch, J., Fischer, N. & Grundhoff, A., 20.09.2022, In: CELL REP MED. 3, 9, 100735.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Estrogen Receptor Alpha Gene Amplification Is an Independent Predictor of Long-Term Outcome in Postmenopausal Patients with Endocrine-Responsive Early Breast Cancer

    Singer, C. F., Holst, F., Steurer, S., Burandt, E. C., Lax, S. F., Jakesz, R., Rudas, M., Stöger, H., Greil, R., Sauter, G., Filipits, M., Simon, R., Gnant, M. & ABCSG, 15.09.2022, In: CLIN CANCER RES. 28, 18, p. 4112-4120 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Synaptophysin and chromogranin A expression analysis in human tumors

    Uhlig, R., Dum, D., Gorbokon, N., Menz, A., Büscheck, F., Luebke, A. M., Hube-Magg, C., Hinsch, A., Höflmayer, D., Fraune, C., Möller, K., Bernreuther, C., Lebok, P., Weidemann, S., Lennartz, M., Jacobsen, F., Clauditz, T. S., Sauter, G., Wilczak, W., Steurer, S., Burandt, E., Krech, R., Krech, T., Marx, A. H., Simon, R. & Minner, S., 15.09.2022, In: MOL CELL ENDOCRINOL. 555, 111726.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Das intimale Sarkom der Pulmonalarterie – Fallbericht einer seltenen Differenzialdiagnose der chronisch thromboembolischen pulmonalen Hypertonie

    Pott, J., Gräfin zu Reventlow, P., Simon, M., Steurer, S., Harbaum, L., Henes, F. O. & Klose, H., 14.09.2022, In: PNEUMOLOGIE. 76, 9, p. 633-638 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma

    Margeta, M. A., Yin, Z., Madore, C., Pitts, K. M., Letcher, S. M., Tang, J., Jiang, S., Gauthier, C. D., Silveira, S. R., Schroeder, C. M., Lad, E. M., Proia, A. D., Tanzi, R. E., Holtzman, D. M., Krasemann, S., Chen, D. F. & Butovsky, O., 13.09.2022, In: IMMUNITY. 55, 9, p. 1627-1644.e7 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Characterization of RARRES1 Expression on Circulating Tumor Cells as Unfavorable Prognostic Marker in Resected Pancreatic Ductal Adenocarcinoma Patients

    Nitschke, C., Markmann, B., Tölle, M., Kropidlowski, J., Belloum, Y., Goetz, M. R., Schlüter, H., Kwiatkowski, M., Sinn, M., Izbicki, J., Pantel, K., Güngör, C., Uzunoglu, F. G. & Wikman, H., 10.09.2022, In: CANCERS. 14, 18, 4405.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. The effects of SARS-CoV-2 virus type and of vaccination status on causes of death over the course of the COVID-19 pandemic

    Paparoupa, M., Schröder, A. S., Braunsteiner, J., Addo, M. M., Lütgehetmann, M., Roedl, K., Kluge, S., Ondruschka, B. & Wichmann, D., 05.09.2022, In: DTSCH ARZTEBL INT. 119, 35-36, p. 607-608 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  41. SARS-CoV-2 infects human cardiomyocytes promoted by inflammation and oxidative stress

    Tangos, M., Budde, H., Kolijn, D., Sieme, M., Zhazykbayeva, S., Lódi, M., Herwig, M., Gömöri, K., Hassoun, R., Robinson, E. L., Meister, T. L., Jaquet, K., Kovács, Á., Mustroph, J., Evert, K., Babel, N., Fagyas, M., Lindner, D., Püschel, K., Westermann, D., Mannherz, H. G., Paneni, F., Pfaender, S., Tóth, A., Mügge, A., Sossalla, S. & Hamdani, N., 01.09.2022, In: INT J CARDIOL. 362, p. 196-205 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. SMARCB1-deficient and SMARCA4-deficient Malignant Brain Tumors With Complex Copy Number Alterations and TP53 Mutations May Represent the First Clinical Manifestation of Li-Fraumeni Syndrome

    Hasselblatt, M., Thomas, C., Federico, A., Nemes, K., Johann, P. D., Bison, B., Bens, S., Dahlum, S., Kordes, U., Redlich, A., Lessel, L., Pajtler, K. W., Mawrin, C., Schüller, U., Nolte, K., Kramm, C. M., Hinz, F., Sahm, F., Giannini, C., Penkert, J., Kratz, C. P., Pfister, S. M., Siebert, R., Paulus, W., Kool, M. & Frühwald, M. C., 01.09.2022, In: AM J SURG PATHOL. 46, 9, p. 1277-1283 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Vertical anti-SARS-CoV-2 monoclonal antibody transfer from mothers to HIV-exposed and unexposed infants

    Kobbe, R., Schulze-Sturm, U., Kurnaz, P., Rau, C., Tallarek, A-C., Lütgehetmann, M., Jordan, S. & Schmiedel, S., 01.09.2022, In: AIDS. 36, 11, p. 1613-1615 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  44. Akkreditierung in der Pathologie und Neuropathologie: Wege und Pitfalls

    Holl-Ulrich, K., Hagel, C., Köhler, G. & Flechtenmacher, C., 09.2022, In: PATHOLOGIE. 43, 5, p. 338-345 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleTransfer

  45. Anti-SARS-CoV-2 antibodies in breast milk during lactation after infection or vaccination: A cohort study

    Olearo, F., Radmanesh, L-S., Felber, N., von Possel, R., Emmerich, P., Pekarek, N., Pfefferle, S., Nörz, D., Hansen, G., Diemert, A., Aepfelbacher, M., Hecher, K., Lütgehetmann, M., Arck, P. C. & Tallarek, A-C., 09.2022, In: J REPROD IMMUNOL. 153, 103685.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Assessing and improving the validity of COVID-19 autopsy studies - A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analyses

    Krasemann, S., Dittmayer, C., von Stillfried, S., Meinhardt, J., Heinrich, F., Hartmann, K., Pfefferle, S., Thies, E., von Manitius, R., Aschman, T. A. D., Radke, J., Osterloh, A., Schmid, S., Buhl, E. M., Ihlow, J., Dubois, F., Arnhold, V., Elezkurtaj, S., Horst, D., Hocke, A., Timm, S., Bachmann, S., Corman, V., Goebel, H-H., Matschke, J., Stanelle-Bertram, S., Gabriel, G., Seilhean, D., Adle-Biassette, H., Ondruschka, B., Ochs, M., Stenzel, W., Heppner, F. L., Boor, P., Radbruch, H., Laue, M. & Glatzel, M., 09.2022, In: EBIOMEDICINE. 83, 104193.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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