Department of Pediatric Hematology and Oncology

Publications

  1. 2017
  2. The role of constitutive activation of FMS-related tyrosine kinase-3 andmutational status in infants with-rearranged acute lymphoblastic leukemia

    Fedders, H., Alsadeq, A., Schmäh, J., Vogiatzi, F., Zimmermann, M., Möricke, A., Lenk, L., Stadt, U. Z., Horstmann, M. A., Pieters, R., Schrappe, M., Stanulla, M., Cario, G. & Schewe, D. M., 11.2017, In: HAEMATOLOGICA. 102, 11, p. e438-e442

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia

    Steeghs, E. M. P., Jerchel, I. S., de Goffau-Nobel, W., Hoogkamer, A. Q., Boer, J. M., Boeree, A., van de Ven, C., Koudijs, M. J., Besselink, N. J. M., de Groot-Kruseman, H. A., Zwaan, C. M., Horstmann, M. A., Pieters, R. & den Boer, M. L., 27.10.2017, In: ONCOTARGET. 8, 52, p. 89923-89938 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent

    Lévy, C., Amirache, F., Girard-Gagnepain, A., Frecha, C., Roman-Rodríguez, F. J., Bernadin, O., Costa, C., Nègre, D., Gutierrez-Guerrero, A., Vranckx, L. S., Clerc, I., Taylor, N., Thielecke, L., Cornils, K., Bueren, J. A., Rio, P., Gijsbers, R., Cosset, F-L. & Verhoeyen, E., 24.10.2017, In: Blood Adv. 1, 23, p. 2088-2104 17 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Das CARE-for-CAYA-Programm. Präventionskonzept für junge Menschen nach Krebserkrankung

    Quidde, J., Koch, B., Salchow, J., Jensen, W., von Grundherr, J., Escherich, G., Rutkowski, S. J., Schulz-Kindermann, F., Bergelt, C., Bokemeyer, C., Sokalska-Duhme, M., Bielak, S., Calaminus, G., Classen, C-F., Rössig, C., Faber, J., Faller, H., Hilgendorf, I., Langer, T., Metzler, M., Schuster, S., Niemeyer, C., Pierce, A., Reinhardt, D., Dirksen, U., Sander, A., Köhler, M. & Stein, A., 23.10.2017, In: Forum. Das offizielle Magazin der Deutschen Krebsgesellschaft e.V.. 32, 06, p. 479-484

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures

    Schwalbe, E. C., Hicks, D., Rafiee, G., Bashton, M., Gohlke, H., Enshaei, A., Potluri, S., Matthiesen, J., Mather, M., Taleongpong, P., Chaston, R., Silmon, A., Curtis, A., Lindsey, J. C., Crosier, S., Smith, A. J., Goschzik, T., Doz, F., Rutkowski, S., Lannering, B., Pietsch, T., Bailey, S., Williamson, D. & Clifford, S. C., 18.10.2017, In: SCI REP-UK. 7, 1, p. 13421

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Intracystic interferon-alpha in pediatric craniopharyngioma patients: an international multicenter assessment on behalf of SIOPE and ISPN

    Kilday, J-P., Caldarelli, M., Massimi, L., Chen, R. H-H., Lee, Y. Y., Liang, M-L., Parkes, J., Naiker, T., van Veelen, M-L., Michiels, E., Mallucci, C., Pettorini, B., Meijer, L., Dorfer, C., Czech, T., Diezi, M., Schouten-van Meeteren, A. Y. N., Holm, S., Gustavsson, B., Benesch, M., Müller, H. L., Hoffmann, A., Rutkowski, S., Flitsch, J., Escherich, G., Grotzer, M., Spoudeas, H. A., Azquikina, K., Capra, M., Jiménez-Guerra, R., MacDonald, P., Johnston, D. L., Dvir, R., Constantini, S., Kuo, M-F., Yang, S-H. & Bartels, U., 01.10.2017, In: NEURO-ONCOLOGY. 19, 10, p. 1398-1407 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors

    Neumann, J. E., Wefers, A. K., Lambo, S., Bianchi, E., Bockstaller, M., Dorostkar, M. M., Meister, V., Schindler, P., Korshunov, A., von Hoff, K., Nowak, J., Warmuth-Metz, M., Schneider, M. R., Renner-Müller, I., Merk, D. J., Shakarami, M., Sharma, T., Chavez, L., Glass, R., Chan, J. A., Taketo, M. M., Neumann, P., Kool, M. & Schüller, U., 10.2017, In: NAT MED. 23, 10, p. 1191-1202

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Development and Initial Validation of the Macrophage Activation Syndrome/Primary Hemophagocytic Lymphohistiocytosis Score, a Diagnostic Tool that Differentiates Primary Hemophagocytic Lymphohistiocytosis from Macrophage Activation Syndrome

    Minoia, F., Bovis, F., Davì, S., Insalaco, A., Lehmberg, K., Shenoi, S., Weitzman, S., Espada, G., Gao, Y-J., Anton, J., Kitoh, T., Kasapcopur, O., Sanner, H., Merino, R., Astigarraga, I., Alessio, M., Jeng, M., Chasnyk, V., Nichols, K. E., Huasong, Z., Li, C., Micalizzi, C., Ruperto, N., Martini, A., Cron, R. Q., Ravelli, A., Horne, A. & Pediatric Rheumatology International Trials Organization, the Childhood Arthritis and Rheumatology Research Alliance, the Pediatric Rheumatology Collaborative Study Group, and the Histiocyte Society, 10.2017, In: J PEDIATR-US. 189, p. 72-78.e3

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Genetic barcodes facilitate competitive clonal analyses in vivo

    Aranyossy, T., Thielecke, L., Glauche, I., Fehse, B. & Cornils, K., 10.2017, In: HUM GENE THER. 28, 10, p. 926-937

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Neurotoxic side effects in children with refractory or relapsed T-cell malignancies treated with nelarabine based therapy

    Kuhlen, M., Bleckmann, K., Möricke, A., Schrappe, M., Vieth, S., Escherich, G., Bronsema, A., Vonalt, A., Queudeville, M., Zwaan, C. M., Ebinger, M., Debatin, K-M., Klingebiel, T., Koscielniak, E., Rossig, C., Burkhardt, B., Kolb, R., Eckert, C., Borkhardt, A., von Stackelberg, A. & Chen-Santel, C., 10.2017, In: BRIT J HAEMATOL. 179, 2, p. 272-283

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Osteonecrosis develops independently from radiological leukemic infiltration of bone in adolescents with acute lymphoblastic leukemia - first findings of the OPAL trial

    Krull, K., Kunstreich, M., Klasen-Sansone, J., Kloetgen, A., Gruener, F., Escherich, G., Bleckmann, K., Moericke, A., Schrappe, M., Jorch, N., Steinbach, D., Classen, C-F., Guggemos, A., Kolb, R., Klee, D., Borkhardt, A. & Kuhlen, M., 10.2017, In: LEUKEMIA LYMPHOMA. 58, 10, p. 2363-2369 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Versorgung von Patienten nach Krebserkrankung im Kindes-, Jugend- oder jungen Erwachsenenalter

    Quidde, J., Koch, B., Salchow, J., Jensen, W., von Grundherr, J., Escherich, G., Rutkowski, S. J., Schulz-Kindermann, F., Bergelt, C., Bokemeyer, C., Sokalska-Duhme, M., Bielak, S., Calaminus, G., Classen, C-F., Rössig, C., Faber, J., Faller, H., Hilgendorf, I., Langer, T., Metzler, M., Schuster, S., Niemeyer, C., Pierce, A., Reinhardt, D., Dirksen, U., Sander, A., Köhler, M. & Stein, A., 10.2017, In: J Onkol - Z Onkol Fortb. 2017, 10, p. 862-866

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Asparaginase-associated pancreatitis in childhood acute lymphoblastic leukaemia: an observational Ponte di Legno Toxicity Working Group study

    Wolthers, B. O., Frandsen, T. L., Baruchel, A., Attarbaschi, A., Barzilai, S., Colombini, A., Escherich, G., Grell, K., Inaba, H., Kovacs, G., Liang, D-C., Mateos, M., Mondelaers, V., Möricke, A., Ociepa, T., Samarasinghe, S., Silverman, L. B., van der Sluis, I. M., Stanulla, M., Vrooman, L. M., Yano, M., Zapotocka, E., Schmiegelow, K. & Ponte di Legno toxicity working group, 09.2017, In: LANCET ONCOL. 18, 9, p. 1238-1248 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Dark-field imaging in coronary atherosclerosis

    Hetterich, H., Webber, N., Willner, M., Herzen, J., Birnbacher, L., Auweter, S., Schüller, U., Bamberg, F., Notohamiprodjo, S., Bartsch, H., Wolf, J., Marschner, M., Pfeiffer, F., Reiser, M. & Saam, T., 09.2017, In: EUR J RADIOL. 94, p. 38-45 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Geographical variability in survival of European children with central nervous system tumours

    Gatta, G., Peris-Bonet, R., Visser, O., Stiller, C. A., Marcos-Gragera, R., Sánchez, M-J., Lacour, B., Kaatsch, P., Berrino, F., Rutkowski, S., Botta, L. & EUROCARE-5 Working Group, 09.2017, In: EUR J CANCER. 82, p. 137-148 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Tropomyosin receptor kinase C (TrkC) expression in medulloblastoma: relation to the molecular subgroups and impact on treatment response

    Friedrich, C., Shalaby, T., Oehler, C., Pruschy, M., Seifert, B., Picard, D., Remke, M., Warmuth-Metz, M., Kortmann, R-D., Rutkowski, S., Grotzer, M. A. & von Bueren, A. O., 09.2017, In: CHILD NERV SYST. 33, 9, p. 1463-1471 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. K27M midline gliomas display malignant progression by imaging and histology

    Vettermann, F. J., Neumann, J. E., Suchorska, B., Bartenstein, P., Giese, A., Dorostkar, M. M., Albert, N. L. & Schüller, U., 08.2017, In: NEUROPATH APPL NEURO. 43, 5, p. 458-462

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  19. Mutation patterns in genes encoding interferon signaling and antigen presentation: A pan-cancer survey with implications for the use of immune checkpoint inhibitors

    Budczies, J., Bockmayr, M., Klauschen, F., Endris, V., Fröhling, S., Schirmacher, P., Denkert, C. & Stenzinger, A., 08.2017, In: GENE CHROMOSOME CANC. 56, 8, p. 651-659 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Enzymatic characterization of novel arylsulfatase A variants using human arylsulfatase A-deficient immortalized mesenchymal stromal cells

    Böhringer, J., Santer, R., Schumacher, N., Gieseke, F., Cornils, K., Pechan, M., Kustermann-Kuhn, B., Handgretinger, R., Schöls, L., Harzer, K., Krägeloh-Mann, I. & Müller, I., 31.07.2017, In: HUM MUTAT. 38, 11, p. 1511-1520

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Neurogenesis from Sox2 expressing cells in the adult cerebellar cortex

    Ahlfeld, J., Filser, S., Schmidt, F., Wefers, A. K., Merk, D. J., Glaß, R., Herms, J. & Schüller, U., 21.07.2017, In: SCI REP-UK. 7, 1, p. 6137

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas

    Grausam, K. B., Dooyema, S. D. R., Bihannic, L., Premathilake, H., Morrissy, A. S., Forget, A., Schaefer, A. M., Gundelach, J. H., Macura, S., Maher, D. M., Wang, X., Heglin, A. H., Ge, X., Zeng, E., Puget, S., Chandrasekar, I., Surendran, K., Bram, R. J., Schüller, U., Talyor, M. D., Ayrault, O. & Zhao, H., 15.07.2017, In: CANCER RES. 77, 14, p. 3766-3777 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion

    Cornils, K., Thielecke, L., Winkelmann, D., Aranyossy, T., Lesche, M., Dahl, A., Roeder, I., Fehse, B. & Glauche, I., 14.07.2017, In: MOL CANCER. 16, 1, p. 120

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Enhanced Local Disorder in a Clinically Elusive von Willebrand Factor Provokes High-Affinity Platelet Clumping

    Tischer, A., Machha, V. R., Frontroth, J. P., Brehm, M. A., Obser, T., Schneppenheim, R., Mayne, L., Walter Englander, S. & Auton, M., 07.07.2017, In: J MOL BIOL. 429, 14, p. 2161-2177 17 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Cribriform neuroepithelial tumor: Molecular characterization of a SMARCB1-deficient non-rhabdoid tumor with favorable long-term outcome

    Johann, P. D., Hovestadt, V., Thomas, C., Jeibmann, A., Heß, K., Bens, S., Oyen, F., Hawkins, C., Pierson, C. R., Aldape, K., Kim, S-P., Widing, E., Sumerauer, D., Hauser, P., van Landeghem, F., Ryzhova, M., Korshunov, A., Capper, D., Jones, D. T. W., Pfister, S. M., Schneppenheim, R., Siebert, R., Paulus, W., Frühwald, M. C., Kool, M. & Hasselblatt, M., 07.2017, In: BRAIN PATHOL. 27, 4, p. 411-418

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Efficacy, safety and feasibility of antifungal prophylaxis with posaconazole tablet in paediatric patients after haematopoietic stem cell transplantation

    Döring, M., Cabanillas Stanchi, K. M., Queudeville, M., Feucht, J., Blaeschke, F., Schlegel, P., Feuchtinger, T., Lang, P., Müller, I., Handgretinger, R. & Heinz, W. J., 07.2017, In: J CANCER RES CLIN. 143, 7, p. 1281-1292

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia

    Vesely, C., Frech, C., Eckert, C., Cario, G., Mecklenbräuker, A., Zur Stadt, U., Nebral, K., Kraler, F., Fischer, S., Attarbaschi, A., Schuster, M., Bock, C., Cavé, H., von Stackelberg, A., Schrappe, M., Horstmann, M. A., Mann, G., Haas, O. A. & Panzer-Grümayer, R., 07.2017, In: LEUKEMIA. 31, 7, p. 1491-1501

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. MRI-based quantitative susceptibility mapping (QSM) and R2* mapping of liver iron overload Comparison with SQUID-based biomagnetic liver susceptometry

    Sharma, S. D., Fischer, R., Schoennagel, B. P., Nielsen, P., Kooijman, H., Yamamura, J., Adam, G., Bannas, P., Hernando, D. & Reeder, S. B., 07.2017, In: MAGN RESON MED. 78, 1, p. 264-270

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Refining medulloblastoma subgroups

    Juhnke, B-O., Mynarek, M. & Rutkowski, S., 07.2017, In: LANCET ONCOL. 18, 7, p. 847-848 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  30. The epidemiology of sickle cell disease in Germany following recent large-scale immigration

    Kunz, J. B., Cario, H., Grosse, R., Jarisch, A., Lobitz, S. & Kulozik, A. E., 07.2017, In: PEDIATR BLOOD CANCER. 64, 7

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Building a National Framework for Adolescent and Young Adult Hematology and Oncology and Transition from Pediatric to Adult Care: Report of the Inaugural Meeting of the "AjET" Working Group of the German Society for Pediatric Oncology and Hematology

    Escherich, G., Bielack, S., Maier, S., Braungart, R., Brümmendorf, T. H., Freund, M., Grosse, R., Hoferer, A., Kampschulte, R., Koch, B., Lauten, M., Milani, V., Ross, H., Schilling, F., Wöhrle, D., Cario, H. & Dirksen, U., 06.2017, In: J ADOLESC YOUNG ADUL. 6, 2, p. 194-199

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Radiomic Analysis Reveals Prognostic Information in T1-Weighted Baseline Magnetic Resonance Imaging in Patients With Glioblastoma

    Ingrisch, M., Schneider, M. J., Nörenberg, D., Negrao de Figueiredo, G., Maier-Hein, K., Suchorska, B., Schüller, U., Albert, N., Brückmann, H., Reiser, M., Tonn, J-C. & Ertl-Wagner, B., 06.2017, In: INVEST RADIOL. 52, 6, p. 360-366

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Similar but not the same: Differential diagnosis of HLH and sepsis

    Machowicz, R., Janka, G. & Wiktor-Jedrzejczak, W., 06.2017, In: CRIT REV ONCOL HEMAT. 114, p. 1-12 12 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  34. Spatial heterogeneity in medulloblastoma

    Morrissy, A. S., Cavalli, F. M. G., Remke, M., Ramaswamy, V., Shih, D. J. H., Holgado, B. L., Farooq, H., Donovan, L. K., Garzia, L., Agnihotri, S., Kiehna, E. N., Mercier, E., Mayoh, C., Papillon-Cavanagh, S., Nikbakht, H., Gayden, T., Torchia, J., Picard, D., Merino, D. M., Vladoiu, M., Luu, B., Wu, X., Daniels, C., Horswell, S., Thompson, Y. Y., Hovestadt, V., Northcott, P. A., Jones, D. T. W., Peacock, J., Wang, X., Mack, S. C., Reimand, J., Albrecht, S., Fontebasso, A. M., Thiessen, N., Li, Y., Schein, J. E., Lee, D., Carlsen, R., Mayo, M., Tse, K., Tam, A., Dhalla, N., Ally, A., Chuah, E., Cheng, Y., Plettner, P., Li, H. I., Corbett, R. D., Wong, T., Long, W., Loukides, J., Buczkowicz, P., Hawkins, C. E., Tabori, U., Rood, B. R., Myseros, J. S., Packer, R. J., Korshunov, A., Lichter, P., Kool, M., Pfister, S. M., Schüller, U., Dirks, P. B., Huang, A., Bouffet, E., Rutka, J. T., Bader, G. D., Swanton, C., Ma, Y., Moore, R. A., Mungall, A. J., Majewski, J., Jones, S. J. M., Das, S., Malkin, D., Jabado, N., Marra, M. A. & Taylor, M. D., 05.2017, In: NAT GENET. 49, 5, p. 780-788 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Evaluation of age-dependent treatment strategies for children and young adults with pineoblastoma: analysis of pooled European Society for Paediatric Oncology (SIOP-E) and US Head Start data

    Mynarek, M., Pizer, B., Dufour, C., van Vuurden, D., Garami, M., Massimino, M., Fangusaro, J., Davidson, T., Gil-da-Costa, M. J., Sterba, J., Benesch, M., Gerber, N., Juhnke, B. O., Kwiecien, R., Pietsch, T., Kool, M., Clifford, S., Ellison, D. W., Giangaspero, F., Wesseling, P., Gilles, F., Gottardo, N., Finlay, J. L., Rutkowski, S. & von Hoff, K., 01.04.2017, In: NEURO-ONCOLOGY. 19, 4, p. 576-585

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology

    Ripperger, T., Bielack, S. S., Borkhardt, A., Brecht, I. B., Burkhardt, B., Calaminus, G., Debatin, K-M., Deubzer, H., Dirksen, U., Eckert, C., Eggert, A., Erlacher, M., Fleischhack, G., Frühwald, M. C., Gnekow, A., Goehring, G., Graf, N., Hanenberg, H., Hauer, J., Hero, B., Hettmer, S., von Hoff, K., Horstmann, M., Hoyer, J., Illig, T., Kaatsch, P., Kappler, R., Kerl, K., Klingebiel, T., Kontny, U., Kordes, U., Körholz, D., Koscielniak, E., Kramm, C. M., Kuhlen, M., Kulozik, A. E., Lamottke, B., Leuschner, I., Lohmann, D. R., Meinhardt, A., Metzler, M., Meyer, L. H., Moser, O., Nathrath, M., Niemeyer, C. M., Nustede, R., Pajtler, K. W., Paret, C., Rasche, M., Reinhardt, D., Rieß, O., Russo, A., Rutkowski, S., Schlegelberger, B., Schneider, D., Schneppenheim, R., Schrappe, M., Schroeder, C., von Schweinitz, D., Simon, T., Sparber-Sauer, M., Spix, C., Stanulla, M., Steinemann, D., Strahm, B., Temming, P., Thomay, K., von Bueren, A. O., Vorwerk, P., Witt, O., Wlodarski, M., Wössmann, W., Zenker, M., Zimmermann, S., Pfister, S. M. & Kratz, C. P., 04.2017, In: AM J MED GENET A. 173, 4, p. 1017-1037 21 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  37. Ex Vivo Assessment of Coronary Atherosclerotic Plaque by Grating-Based Phase-Contrast Computed Tomography: Correlation With Optical Coherence Tomography

    Habbel, C., Hetterich, H., Willner, M., Herzen, J., Steigerwald, K., Auweter, S., Schüller, U., Hausleiter, J., Massberg, S., Reiser, M., Pfeiffer, F., Saam, T. & Bamberg, F., 04.2017, In: INVEST RADIOL. 52, 4, p. 223-231

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome

    Witkowski, M. T., Hu, Y., Roberts, K. G., Boer, J. M., McKenzie, M. D., Liu, G. J., Le Grice, O. D., Tremblay, C. S., Ghisi, M., Willson, T. A., Horstmann, M. A., Aifantis, I., Cimmino, L., Frietze, S., den Boer, M. L., Mullighan, C. G., Smyth, G. K. & Dickins, R. A., 06.03.2017, In: J EXP MED. 214, 3, p. 773-791 19 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Cardiac Function Remains Impaired Despite Reversible Cardiac Remodeling after Acute Experimental Viral Myocarditis

    Becher, P. M., Gotzhein, F., Klingel, K., Escher, F., Blankenberg, S., Westermann, D. & Lindner, D., 02.03.2017, In: J IMMUNOL RES.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Kaposiformes Hämangioendotheliom mit Kasabach-Merritt-Syndrom: erfolgreiche Therapie mit Sirolimus

    Reichel, A., Hamm, H., Wiegering, V., Wiewrodt, B., Neubauer, H., Ernestus, K. & Winkler, B., 03.2017, In: J DTSCH DERMATOL GES. 15, 3, p. 329-331 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  41. Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome: successful treatment with sirolimus

    Reichel, A., Hamm, H., Wiegering, V., Wiewrodt, B., Neubauer, H., Ernestus, K. & Winkler, B., 03.2017, In: J DTSCH DERMATOL GES. 15, 3, p. 329-331 3 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  42. Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients

    Scheijen, B., Boer, J. M., Marke, R., Tijchon, E., van Ingen Schenau, D., Waanders, E., van Emst, L., van der Meer, L. T., Pieters, R., Escherich, G., Horstmann, M., Sonneveld, E., Venn, N., Sutton, R., Dalla-Pozza, L., Kuiper, R. P., Hoogerbrugge, P. M., den Boer, M. L. & van Leeuwen, F. N., 03.2017, In: HAEMATOLOGICA. 102, 3, p. 541-551

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Evolution of disease activity and biomarkers on and off rapamycin in 28 patients with autoimmune lymphoproliferative syndrome

    Klemann, C., Esquivel, M., Magerus-Chatinet, A., Lorenz, M. R., Fuchs, I., Neveux, N., Castelle, M., Rohr, J., Bettoni da Cunha, C., Ebinger, M., Kobbe, R., Kremens, B., Kollert, F., Gambineri, E., Lehmberg, K., Seidel, M. G., Siepermann, K., Voelker, T., Schuster, V., Goldacker, S., Schwarz, K., Speckmann, C., Picard, C., Fischer, A., Rieux-Laucat, F., Ehl, S., Rensing-Ehl, A. & Neven, B., 02.2017, In: HAEMATOLOGICA. 102, 2, p. e52-e56

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  44. Inherited Thrombotic Thrombocytopenic Purpura (Upshaw Schulman Syndrome) as Differential Diagnosis to Neonatal Septicaemia with Disseminated Intravascular Coagulation - a Case Series

    Lehmberg, K., Hassenpflug, W. A., Klaassen, I., Hillebrand, G., Oyen, F., Budde, U., Singer, D. & Schneppenheim, R., 02.2017, In: Z GEBURTSH NEONATOL. 221, 1, p. 39-42

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Left atrial active contractile function parameters assessed by cardiac MR are sensitive to myocardial iron

    Wehbe, M., Yamamura, J., Fischer, R., Grosse, R., Berliner, C., Graessner, J., Lund, G., Adam, G. & Schoennagel, B. P., 02.2017, In: J MAGN RESON IMAGING. 45, 2, p. 535-541

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Liver transplantation as a potentially lifesaving measure in neuroblastoma stage 4S

    Holsten, T., Schuster, T., Grabhorn, E., Hero, B. & Frühwald, M. C., 02.2017, In: PEDIATR HEMAT ONCOL. 34, 1, p. 17-23 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Mutations in EXTL3 Cause Neuro-immuno-skeletal Dysplasia Syndrome

    Oud, M. M., Tuijnenburg, P., Hempel, M., van Vlies, N., Ren, Z., Ferdinandusse, S., Jansen, M. H., Santer, R., Johannsen, J., Bacchelli, C., Alders, M., Li, R., Davies, R., Dupuis, L., Cale, C. M., Wanders, R. J. A., Pals, S. T., Ocaka, L., James, C., Müller, I., Lehmberg, K., Strom, T., Engels, H., Williams, H. J., Beales, P., Roepman, R., Dias, P., Brunner, H. G., Cobben, J-M., Hall, C., Hartley, T., Le Quesne Stabej, P., Mendoza-Londono, R., Davies, E. G., de Sousa, S. B., Lessel, D., Arts, H. H. & Kuijpers, T. W., 02.2017, In: AM J HUM GENET. 100, 2, p. 281-296

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Outcome in unresectable glioblastoma: MGMT promoter methylation makes the difference

    Thon, N., Thorsteinsdottir, J., Eigenbrod, S., Schüller, U., Lutz, J., Kreth, S., Belka, C., Tonn, J-C., Niyazi, M. & Kreth, F. W., 02.2017, In: J NEUROL. 264, 2, p. 350-358 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Primary and secondary hemophagocytic lymphohistiocytosis have different patterns of T-cell activation, differentiation and repertoire

    Ammann, S., Lehmberg, K., Zur Stadt, U., Janka-Schaub, G., Rensing-Ehl, A., Klemann, C., Heeg, M., Bode, S., Fuchs, I., Ehl, S. & HLH study of the GPOH, 02.2017, In: EUR J IMMUNOL. 47, 2, p. 364-373

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Von Willebrand factor processing

    Brehm, M. A., 31.01.2017, In: HAMOSTASEOLOGIE. 37, 1, p. 59-72 14 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  51. Mutation G1629E Increases von Willebrand Factor Cleavage via a Cooperative Destabilization Mechanism

    Aponte-Santamaría, C., Lippok, S., Mittag, J. J., Obser, T., Schneppenheim, R., Baldauf, C., Gräter, F., Budde, U. & Rädler, J. O., 10.01.2017, In: BIOPHYS J. 112, 1, p. 57-65 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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