Research ExplorerResearch UnitsDepartment of Pediatric Hematology and Oncology Publications

Department of Pediatric Hematology and Oncology

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Publications

  1. 2004

  2. Standardisierte Diagnostik des von-Willebrand-Syndroms

    Budde, U., Drewke, E., Will, K. & Schneppenheim, R., 01.02.2004, In: HAMOSTASEOLOGIE. 24, 1, p. 12-26 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Thrombotisch-thrombozytopenische Purpura im Kindesalter

    Hassenpflug, W-A., Angerhaus, D., Budde, U., Obser, T. & Schneppenheim, R., 01.02.2004, In: HAMOSTASEOLOGIE. 24, 1, p. 71-6 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. A91V is a polymorphism in the perforin gene not causative of an FHLH phenotype.

    Udo, Z. S., Beutel, K., Weber, B., Kabisch, H., Schneppenheim, R. & Janka-Schaub, G., 2004, In: BLOOD. 104, 6, p. 1910 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.

    Du, J., Widlund, H. R., Horstmann, M., Ramaswamy, S., Ross, K., Huber, W. E., Nishimura, E. K., Golub, T. R. & Fisher, D. E., 2004, In: CANCER CELL. 6, 6, p. 565-576 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment.

    Holleman, A., Cheok, M. H., Boer, D., Monique, L., Yang, W., Veerman, A. J. P., Kazemier, K. M., Pei, D., Cheng, C., Pui, C-H., Janka-Schaub, G., Janka-Schaub, G. E., Pieters, R. & Evans, W. E., 2004, In: NEW ENGL J MED. 351, 6, p. 533-542 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Gingivitis as probable source of a thoracic actinomycosis due to Actinomyces israelii and Actinobacillus actinomycetemcomitans.

    Kordes, U., Beutel, K., Cachovan, G., Schäfer, H., Helmke, K. & Sobottka, I., 2004, In: ARCH DIS CHILD. 89, 10, p. 895 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. In vitro drug-resistance profile in infant acute lymphoblastic leukemia in relation to age, MLL rearrangements and immunophenotype.

    Woerden, R., Beverloo, U., Veerman, U., Camitta, U., Loonen, U., Wering, V., Slater, U., Harbott, J., Den, B., Ludwig, U., Haas, U., Janka-Schaub, G. & Pieters, R., 2004, In: LEUKEMIA. 18, 3, p. 521-529 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Limited specificity of promoter constructs for gene therapy in osteosarcoma.

    Pollmann, A., Kabisch, H., Block, A., Müller, J. & Hellwinkel, O., 2004, In: INT J MOL MED. 14, 4, p. 737-742 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Modern management of children with haemophagocytic lymphohistiocytosis.

    Janka-Schaub, G. & Schneider, E. M., 2004, In: BRIT J HAEMATOL. 124, 1, p. 4-14 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Multidrug resistance genes in infant acute lymphoblastic leukemia: Ara-C is not a substrate for the breast cancer resistance protein.

    Stam, U., van Den, H-E., Den, B., Ebus, U., Janka-Schaub, G., Allen, U. & Pieters, R., 2004, In: LEUKEMIA. 18, 1, p. 78-83 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Permanent consequences in Langerhans cell histiocytosis patients: a pilot study from the Histiocyte Society-Late Effects Study Group.

    Haupt, R., Nanduri, V., Calevo, M. G., Bernstrand, C., Braier, J. L., Broadbent, V., Rey, G., McClain, K. L., Janka-Schaub, G. & Egeler, R. M., 2004, In: PEDIATR BLOOD CANCER. 42, 5, p. 438-444 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Secondary cytogenetic aberrations in childhood Philadelphia chromosome positive acute lymphoblastic leukemia are nonrandom and may be associated with outcome.

    Heerema, N. A., Harbott, J., Galimberti, S., Camitta, B. M., Gaynon, P. S., Janka-Schaub, G., Kamps, W., Basso, G., Pui, C-H., Schrappe, M., Auclerc, M-F., Carroll, A. J., Conter, V., Harrison, C. J., Pullen, J., Raimondi S, C., Richards, S., Riehm, H., Sather, H. N., Shuster, J. J., Silverman, L. B., Valsecchi, M. G. & Aricò, M., 2004, In: LEUKEMIA. 18, 4, p. 693-702 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Severe ADAMTS-13 deficiency in childhood.

    Schneppenheim, R., Ulrich, B., Hassenpflug, W. & Obser, T., 2004, In: SEMIN HEMATOL. 41, 1, p. 83-89 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. [Thrombotic thrombocytopenic purpura in childhood]

    Hassenpflug, W-A., Angerhaus, D., Budde, U., Obser, T. & Schneppenheim, R., 2004, In: HAMOSTASEOLOGIE. 24, 1, p. 71-76 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. 2003

  17. Identification and characterisation of clonal incomplete T-cell-receptor Vdelta2-Ddelta3/Ddelta2-Ddelta3 rearrangements by denaturing high-performance liquid chromatography and subsequent fragment collection: implications for minimal residual disease monitoring in childhood acute lymphoblastic leukemia

    zur Stadt, U., Eckert, C., Rischewski, J., Michael, K., Golta, S., Müller, M., Schneppenheim, R. & Kabisch, H., 25.07.2003, In: J CHROMATOGR B. 792, 2, p. 287-98 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Receptor activator of nuclear factor kappaB ligand plays a nonredundant role in doxorubicin-induced apoptosis

    Müller, I., Pfister, S. M., Grohs, U., Zweigner, J., Handgretinger, R., Niethammer, D. & Bruchelt, G., 15.04.2003, In: CANCER RES. 63, 8, p. 1772-5 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. The molecular basis of cryptorchidism

    Ivell, R. & Hartung, S., 01.04.2003, In: MOL HUM REPROD. 9, 4, p. 175-81 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research

  20. 2% Hämophilie-A-Patienten ohne Mutation im FVIII-Gen

    Uen, C., Oldenburg, J., Schröder, J., Brackmann, H-J., Schramm, W., Schwaab, R., Schneppenheim, R. & Graw, J., 01.02.2003, In: HAMOSTASEOLOGIE. 23, 1, p. 1-5 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Large-scale isolation of CD133+ progenitor cells from G-CSF mobilized peripheral blood stem cells

    Gordon, P. R., Leimig, T., Babarin-Dorner, A., Houston, J., Holladay, M., Mueller, I., Geiger, T. & Handgretinger, R., 01.2003, In: BONE MARROW TRANSPL. 31, 1, p. 17-22 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Cell proliferation is related to in vitro drug resistance in childhood acute leukaemia.

    Kaaijk, P., Kaspers, G. J. L., Van Wering, E. R., Broekema, G. J., Loonen, A. H., Hählen, K., Schmiegelow, K., Janka-Schaub, G., Henze, G., Creutzig, U. & Veerman, A. J. P., 2003, In: BRIT J CANCER. 88, 5, p. 775-781 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Children may not benefit from neuroblastoma screening at 1 year of age. Updated results of the population based controlled trial in Germany.

    Schilling, F. H., Spix, C., Berthold, F., Erttmann, R., Sander, J., Treuner, J. & Michaelis, J., 2003, In: CANCER LETT. 197, 1-2, p. 19-28 1-2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements.

    Pui, C-H., Chessells, J. M., Camitta, B., Baruchel, A., Biondi, A., Boyett, J. M., Carroll, A., Eden, O. B., Evans, W. E., Gadner, H., Harbott, J., Harms, D. O., Harrison, C. J., Harrison, P. L., Heerema, N., Janka-Schaub, G., Kamps, W., Masera, G., Pullen, J., Raimondi S, C., Richards, S., Riehm, H., Sallan, S., Sather, H., Shuster, J., Silverman, L. B., Valsecchi, M. G., Vilmer, E., Zhou, Y., Gaynon, P. S. & Schrappe, M., 2003, In: LEUKEMIA. 17, 4, p. 700-706 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Congenital dyserythropoietic anemia type II: epidemiology, clinical appearance, and prognosis based on long-term observation.

    Heimpel, H., Anselstetter, V., Chrobak, L., Denecke, J., Einsiedler, B., Gallmeier, K., Griesshammer, A., Marquardt, T., Janka-Schaub, G., Kron, M. & Kohne, E., 2003, In: BLOOD. 102, 13, p. 4576-4581 13.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia.

    Stam, R. W., Boer, D., Monique, L., Meijerink, J. P. P., Ebus, M. E. G., Peters, G. J., Janka-Schaub, G., Janka-Schaub, G. E., Armstrong, S. A., Korsmeyer, S. J. & Pieters, R., 2003, In: BLOOD. 101, 4, p. 1270-1276 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Effective treatment of hereditary haemochromatosis with desferrioxamine in selected cases.

    Nielsen, P., Fischer, R., Buggisch, P. & Janka-Schaub, G., 2003, In: BRIT J HAEMATOL. 123, 5, p. 952-953 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. High-performance liquid chromatographic assay of metabolites of thioguanine and mercaptopurine in capillary blood.

    Erb, N., Haverland, U., Harms, D. O., Escherich, G. & Janka-Schaub, G., 2003, In: J CHROMATOGR B. 796, 1, p. 87-94 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Infantile cobalamin deficiency with cerebral lactate accumulation and sustained choline depletion.

    Horstmann, M., Neumaier-Probst, E., Lukacs, Z., Steinfeld, R., Ullrich, K. & Kohlschütter, A., 2003, In: NEUROPEDIATRICS. 34, 5, p. 261-264 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Lead-time and overdiagnosis estimation in neuroblastoma screening.

    Spix, C., Michaelis, J., Berthold, F., Erttmann, R., Sander, J. & Schilling, F. H., 2003, In: STAT MED. 22, 18, p. 2877-2892 18.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. MLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanoma.

    Du, J., Miller, A. J., Widlund, H. R., Horstmann, M., Ramaswamy, S. & Fisher, D. E., 2003, In: AM J PATHOL. 163, 1, p. 333-343 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Natural killer deficiency: a minor or major factor in the manifestation of hemophagocytic lymphohistiocytosis?

    Schneider, E. M., Lorenz, I., Walther, P. & Janka-Schaub, G., 2003, In: J PEDIAT HEMATOL ONC. 25, 9, p. 680-683 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia.

    Den, B., Harms, U., Pieters, R., Kazemier, U., Gobel, U., Körholz, D., Graubner, U., Haas, U., Jorch, N., Spaar, U., Kaspers, U., Kamps, U., Does, V. D., Berg, V. D., Wering, V., Janka-Schaub, G. & Janka-Schaub, U., 2003, In: J CLIN ONCOL. 21, 17, p. 3262-3268 17.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Rapid LightCycler assay for identification of the perforin codon 374 Trp --> stop mutation in patients and families with hemophagocytic lymphohistiocytosis (HLH).

    Udo, Z. S., Kabisch, H., Janka-Schaub, G. & Schneider, E. M., 2003, In: Med Pediatr Oncol. 41, 1, p. 26-29 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Resistance to different classes of drugs is associated with impaired apoptosis in childhood acute lymphoblastic leukemia.

    Holleman, A., Boer, D., Monique, L., Janka-Schaub, G., Janka-Schaub, G. E. & Pieters, R., 2003, In: BLOOD. 102, 13, p. 4541-4546 13.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL.

    Stams, U., Wendy, A. G., Den, B., Monique, L., Beverloo, U., Berna, H., Meijerink, U., Jules, P. P., Stigter, U., Rolinda, L., Wering, V., Elisabeth, R., Janka-Schaub, G., Gritta, E., Slater, U., Rosalyn, U., Pieters, U. & Rob, U., 2003, In: BLOOD. 101, 7, p. 2743-2747 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Sequence analysis of the granulysin and granzyme B genes in familial hemophagocytic lymphohistiocytosis.

    Ericson, K. G., Fadeel, B., Andersson, M., Gudmundsson, G. H., Gürgey, A., Yalman, N., Janka-Schaub, G., Nordenskjöld, M. & Henter, J-I., 2003, In: HUM GENET. 112, 1, p. 98-99 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Thioguanine offers no advantage over mercaptopurine in maintenance treatment of childhood ALL: results of the randomized trial COALL-92.

    Harms, D. O., Göbel, U., Spaar, H. J., Graubner, U. B., Jorch, N., Gutjahr, P. & Janka-Schaub, G., 2003, In: BLOOD. 102, 8, p. 2736-2740 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. von Willebrand factor cleaving protease and ADAMTS13 mutations in childhood TTP.

    Schneppenheim, R., Ulrich, B., Oyen, F., Angerhaus, D., Aumann, V., Drewke, E., Hassenpflug, W., Häberle, J., Kentouche, K., Kohne, E., Kurnik, K., Müller-Wiefel, D. E., Obser, T., Santer, R. & Sykora, K-W., 2003, In: BLOOD. 101, 5, p. 1845-1850 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. 2002

  41. Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

    Widlund, H. R., Horstmann, M. A., Price, E. R., Cui, J., Lessnick, S. L., Wu, M., He, X. & Fisher, D. E., 16.09.2002, In: J CELL BIOL. 158, 6, p. 1079-87 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. 11 hemophilia A patients without mutations in the factor VIII encoding gene

    Klopp, N., Oldenburg, J., Uen, C., Schneppenheim, R. & Graw, J., 01.08.2002, In: THROMB HAEMOSTASIS. 88, 2, p. 357-60 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. A large-scale method for T cell depletion: towards graft engineering of mobilized peripheral blood stem cells

    Gordon, P. R., Leimig, T., Mueller, I., Babarin-Dorner, A., Holladay, M. A., Houston, J., Kerst, G., Geiger, T. & Handgretinger, R., 07.2002, In: BONE MARROW TRANSPL. 30, 2, p. 69-74 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Laboratory diagnosis of congenital von Willebrand disease

    Budde, U., Drewke, E., Mainusch, K. & Schneppenheim, R., 01.04.2002, In: SEMIN THROMB HEMOST. 28, 2, p. 173-90 18 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Remission of thrombotic thrombocytopenic purpura in a patient with compound heterozygous deficiency of von Willebrand factor-cleaving protease by infusion of solvent/detergent plasma

    Kentouche, K., Budde, U., Furlan, M., Scharfe, V., Schneppenheim, R. & Zintl, F., 01.01.2002, In: ACTA PAEDIATR. 91, 10, p. 1056-9 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.

    McGill, G. G., Horstmann, M., Widlund, H. R., Du, J., Motyckova, G., Nishimura, E. K., Lin, Y-L., Ramaswamy, S., Avery, W., Ding, H-F., Jordan, S. A., Jackson, I. J., Korsmeyer, S. J., Golub, T. R. & Fisher, D. E., 2002, In: CELL. 109, 6, p. 707-718 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome.

    Zwaan, C. M., Kaspers, G. J. L., Pieters, R., Hählen, K., Janka-Schaub, G., Zantwijk, V., Christina, H., Huismans, D. R., de Vries, E., Rots, M. G., Peters, G. J., Jansen, G., Creutzig, U. & Veerman, A. J. P., 2002, In: BLOOD. 99, 1, p. 245-251 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Hemophagocytic lymphohistiocytosis is associated with deficiencies of cellular cytolysis but normal expression of transcripts relevant to killer-cell-induced apoptosis.

    Schneider, E. M., Lorenz, I., Müller-Rosenberger, M., Steinbach, G., Kron, M. & Janka-Schaub, G., 2002, In: BLOOD. 100, 8, p. 2891-2898 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. Homozygous Factor V Leiden mutation in sickle cell anaemia.

    Kordes, U., Janka-Schaub, G. & Schneppenheim, R., 2002, In: BRIT J HAEMATOL. 116, 1, p. 236 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. Infant acute lymphoblastic leukemia - combined cytogenetic, immunophenotypical and molecular analysis of 77 cases.

    Borkhardt, A., Wuchter, C., Viehmann, S., Pils, S., Teigler-Schlegel, A., Stanulla, M., Zimmermann, M., Ludwig, W-D., Janka-Schaub, G., Schrappe, M. & Harbott, J., 2002, In: LEUKEMIA. 16, 9, p. 1685-1690 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. In vitro drug resistance profile of Philadelphia positive acute lymphoblastic leukemia is heterogeneous and related to age: a report of the Dutch and German Leukemia Study Groups.

    Ramakers-van Woerden, N. L., Pieters, R., Hoelzer, D., Slater, R. M., den Boer, M. L., Loonen, A. H., Harbott, J., Janka-Schaub, G., Ludwig, W-D., Ossenkoppele, G. J., van Wering, E. R. & Veerman, A. J. P., 2002, In: Med Pediatr Oncol. 38, 6, p. 379-386 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. In vitro glucocorticoid resistance in childhood leukemia correlates with receptor affinity determined at 37 degrees C, but not with affinity determined at room temperature.

    Haarman, U., Kaspers, U., Pieters, R., Rottier, U., Den, B., Janka-Schaub, G. & Veerman, U., 2002, In: LEUKEMIA. 16, 9, p. 1882-1884 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. In vivo T cell depletion with pretransplant anti-thymocyte globulin reduces graft-versus-host disease without increasing relapse in good risk myeloid leukemia patients after stem cell transplantation from matched related donors.

    Kröger, N., Zabelina, T., Krüger, W., Renges, H., Stute, N., Rischewski, J., Sonnenberg, S., Ayuk, F., Ayuketang Ayuk, F., Schade, U., Fiegel, H., Erttmann, R., Löliger, C. & Zander, A. R., 2002, In: BONE MARROW TRANSPL. 29, 8, p. 683-689 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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