Department of Neurology
Publications
- 2021
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies
Linsenmeier, L., Mohammadi, B., Shafiq, M., Frontzek, K., Bär, J., Shrivastava, A. N., Damme, M., Song, F., Schwarz, A., Da Vela, S., Massignan, T., Jung, S., Correia, A., Schmitz, M., Puig, B., Hornemann, S., Zerr, I., Tatzelt, J., Biasini, E., Saftig, P., Schweizer, M., Svergun, D., Amin, L., Mazzola, F., Varani, L., Thapa, S., Gilch, S., Schätzl, H., Harris, D. A., Triller, A., Mikhaylova, M., Aguzzi, A., Altmeppen, H. C. & Glatzel, M., 26.11.2021, In: SCI ADV. 7, 48, p. eabj1826Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Safety and Clinical Effects of Switching From Intravenous to Oral Nimodipine Administration in Aneurysmal Subarachnoid Hemorrhage
Göttsche, J., Schweingruber, N., Groth, J. C., Gerloff, C., Westphal, M. & Czorlich, P., 16.11.2021, In: FRONT NEUROL. 12, 748413.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Study Criteria Applied to Real Life-A Multicenter Analysis of Stroke Patients Undergoing Endovascular Treatment in Clinical Practice
Leischner, H., Brekenfeld, C., Meyer, L., Broocks, G., Faizy, T., McDonough, R., Gerloff, C., Thomalla, G., Deb-Chatterji, M., Fiehler, J. & Flottmann, F., 16.11.2021, In: J AM HEART ASSOC. 10, 22, e017919.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response
Piepke, M., Clausen, B. H., Ludewig, P., Vienhues, J. H., Bedke, T., Javidi, E., Rissiek, B., Jank, L., Brockmann, L., Sandrock, I., Degenhardt, K., Jander, A., Roth, V., Schädlich, I. S., Prinz, I., Flavell, R. A., Kobayashi, Y., Renné, T., Gerloff, C., Huber, S., Magnus, T. & Gelderblom, M., 13.11.2021, In: J NEUROINFLAMM. 18, 1, 265.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Alterations in brain morphology by MRI in adults with neurofibromatosis 1
Wang, S., Mautner, V-F., Buchert, R., Flibotte, S., Suppa, P., Friedman, J. M. & Heran, M. K. S., 02.11.2021, In: ORPHANET J RARE DIS. 16, 1, 462.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Assessment of Discrepancies Between Follow-up Infarct Volume and 90-Day Outcomes Among Patients With Ischemic Stroke Who Received Endovascular Therapy
Ganesh, A., Ospel, J. M., Menon, B. K., Demchuk, A. M., McTaggart, R. A., Nogueira, R. G., Poppe, A. Y., Almekhlafi, M. A., Hanel, R. A., Thomalla, G., Holmin, S., Puetz, V., van Adel, B. A., Tarpley, J. W., Tymianski, M., Hill, M. D., Goyal, M. & ESCAPE-NA1 Investigators, 01.11.2021, In: JAMA NETW OPEN. 4, 11, e2132376.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Imaging-based prediction of histological clot composition from admission CT imaging
Hanning, U., Sporns, P. B., Psychogios, M. N., Jeibmann, A., Minnerup, J., Gelderblom, M., Schulte, K., Nawabi, J., Broocks, G., Meyer, L., Krähling, H., Brehm, A., Wildgruber, M., Fiehler, J. & Kniep, H., 01.11.2021, In: J NEUROINTERV SURG. 13, 11, p. 1053-1057 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Possible determinants of long-term adherence to physical activity in multiple sclerosis-theory-based development of a comprehensive questionnaire and results from a German survey study
Riemann-Lorenz, K., Motl, R. W., Casey, B., Coote, S., Daubmann, A. & Heesen, C., 01.11.2021, In: DISABIL REHABIL. 43, 22, p. 3175-3188 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bilaterale Tiefe Hirnstimulation im Theta-Burst-Modus bei Parkinson Patientinnen und Patienten - erste Ergebnisse
Gülke, E., Caffier, J., Gerloff, C. & Pötter-Nerger, M., 11.2021, DGN Kongress 2021. EPO77Research output: SCORING: Contribution to book/anthology › Conference contribution - Poster › Research
Cost-Effectiveness of Magnetic Resonance Imaging-Guided Thrombolysis for Patients With Stroke With Unknown Time of Onset
Muntendorf, L-K., Konnopka, A., König, H-H., Boutitie, F., Ebinger, M., Endres, M., Fiebach, J. B., Thijs, V., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Gerloff, C. & Thomalla, G., 11.2021, In: VALUE HEALTH. 24, 11, p. 1620-1627Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Exercise training and cognitive performance in persons with multiple sclerosis: A systematic review and multilevel meta-analysis of clinical trials
Gharakhanlou, R., Wesselmann, L., Rademacher, A., Lampit, A., Negaresh, R., Kaviani, M., Oberste, M., Motl, R. W., Sandroff, B. M., Bansi, J., Baker, J. S., Heesen, C., Zimmer, P. & Javelle, F., 11.2021, In: MULT SCLER J. 27, 13, p. 1977-1993 17 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Impact of intravenous alteplase on sub-angiographic emboli in high-resolution diffusion-weighted imaging following successful thrombectomy
Broocks, G., Meyer, L., Kabiri, R., Kniep, H. C., McDonough, R., Bechstein, M., van Horn, N., Lindner, T., Sedlacik, J., Cheng, B., Thomalla, G., Schön, G., Fiehler, J., Hanning, U. & Schönfeld, M. H., 11.2021, In: EUR RADIOL. 31, 11, p. 8228-8235 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
White matter degeneration revealed by fiber-specific analysis relates to recovery of hand function after stroke
Cheng, B., Petersen, M., Schulz, R., Boenstrup, M., Krawinkel, L., Gerloff, C. & Thomalla, G., 11.2021, In: HUM BRAIN MAPP. 42, 16, p. 5423-5432 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Patients experiences with multiple sclerosis disease-modifying therapies in daily life - a qualitative interview study
Sippel, A., Riemann-Lorenz, K., Scheiderbauer, J., Kleiter, I., Morrison, R., Kofahl, C. & Heesen, C., 22.10.2021, In: BMC HEALTH SERV RES. 21, 1, p. 1141Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression
Schneider, E., Winzer, R., Rissiek, A., Ricklefs, I., Meyer-Schwesinger, C., Ricklefs, F. L., Bauche, A., Behrends, J., Reimer, R., Brenna, S., Wasielewski, H., Lauten, M., Rissiek, B., Puig, B., Cortesi, F., Magnus, T., Fliegert, R., Müller, C. E., Gagliani, N. & Tolosa, E., 08.10.2021, In: NAT COMMUN. 12, 1, p. 5911Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evaluation of an interactive web-based programme on relapse management for people with multiple sclerosis (POWER@MS2): study protocol for a process evaluation accompanying a randomised controlled trial
Wenzel, L., Heesen, C., Scheiderbauer, J., van de Loo, M., Köpke, S. & Rahn, A. C., 01.10.2021, In: BMJ OPEN. 11, 10, p. e046874Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Current and Long-Term Physical Activity Among Adults with Multiple Sclerosis in the United States: COM-B Variables as Explanatory Factors
Silveira, S. L., Riemann-Lorenz, K., Heesen, C. & Motl, R. W., 10.2021, In: INT J BEHAV MED. 28, 5, p. 561-574 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Decision-making about corticosteroids in relapses of multiple sclerosis - development of a questionnaire based on the theory of planned behaviour
Haker, M., Heesen, C., Wenzel, L., Köpke, S., Rahn, A. C. & Kasper, J., 10.2021, In: MULT SCLER RELAT DIS. 55, 103182.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Elevated early lesion water uptake in acute stroke predicts poor outcome despite successful recanalization - When "tissue clock" and "time clock" are desynchronized
Nawabi, J., Flottmann, F., Kemmling, A., Kniep, H., Leischner, H., Sporns, P., Schön, G., Hanning, U., Thomalla, G., Fiehler, J. & Broocks, G., 10.2021, In: INT J STROKE. 16, 7, p. 863-872 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Endovascular Treatment for Acute Stroke in Cerebral Amyloid Angiopathy
Weller, J. M., Enkirch, S. J., Bogs, C., Braemswig, T. B., Deb-Chatterji, M., Keil, F., Kindler, C., Maywald, S., Schirmer, M. D., Stösser, S., Solymosi, L., Nolte, C. H., Bode, F. J., Petzold, G. C. & German Stroke Registry – Endovascular Treatment (GSR – ET), 10.2021, In: STROKE. 52, 10, p. e581-e585Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evidence for a low-penetrant extended phenotype of rhabdoid tumor predisposition syndrome type 1 from a kindred with gain of SMARCB1 exon 6
Kordes, U., Mautner, V-F., Oyen, F., Hagel, C., Hartmann, C., Heuser, M., Frühwald, M., Hasselblatt, M., Oehl-Huber, K., Siebert, R., Schneppenheim, R. & Schüller, U., 10.2021, In: PEDIATR BLOOD CANCER. 68, 10, p. e29185Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Thrombectomy in Extensive Stroke May Not Be Beneficial and Is Associated With Increased Risk for Hemorrhage
Meyer, L., Bechstein, M., Bester, M., Hanning, U., Brekenfeld, C., Flottmann, F., Kniep, H., van Horn, N., Deb-Chatterji, M., Thomalla, G., Sporns, P., Yeo, L. L-L., Tan, B. Y-Q., Gopinathan, A., Kastrup, A., Politi, M., Papanagiotou, P., Kemmling, A., Fiehler, J., Broocks, G. & German Stroke Registry – Endovascular Treatment (GSR – ET), 10.2021, In: STROKE. 52, 10, p. 3109-3117 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Revidierte Diagnosekriterien für die Neurofibromatose Typ 1 (NF1) ermöglichen eine frühe präzise differenzialdiagnostische Abgrenzung zu anderen RASopathien und erleichtern die Diagnose
Kehrer-Sawatzki, H., Farschtschi, S. C. & Mautner, V-F., 30.09.2021, In: MONATSSCHR KINDERH.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Identification of the factor XII contact activation site enables sensitive coagulation diagnostics
Heestermans, M., Naudin, C., Mailer, R. K., Konrath, S., Klaetschke, K., Jämsä, A., Frye, M., Deppermann, C., Pula, G., Kuta, P., Friese, M. A., Gelderblom, M., Sickmann, A., Preston, R. J. S., Nofer, J-R., Rose-John, S., Butler, L. M., Salomon, O., Stavrou, E. X. & Renné, T., 22.09.2021, In: NAT COMMUN. 12, 1, p. 5596 - 5613Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy
Halliday, A., Bulbulia, R., Bonati, L. H., Chester, J., Cradduck-Bamford, A., Peto, R., Pan, H. & ACST-2 Collaborative Group, 18.09.2021, In: LANCET. 398, 10305, p. 1065-1073 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reversible Ischemic Lesion Hypodensity in Acute Stroke CT Following Endovascular Reperfusion
Broocks, G., McDonough, R., Meyer, L., Bechstein, M., Dipl Ing, H. K., Schön, G., Nawka, M. T., Fiehler, J., Hanning, U., Sporns, P., Barow, E., Minnerup, J. & Kemmling, A., 14.09.2021, In: NEUROLOGY. 97, 11, p. e1075-e1084 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Treatment-Relevant Findings in Transesophageal Echocardiography After Stroke: A Prospective Multicenter Cohort Study
Thomalla, G., Upneja, M., Camen, S., Jensen, M., Schröder, J., Barow, E., Boskamp, S., Ostermeier, B., Kissling, S., Leinisch, E., Tiburtius, C., Clausen, H., Cheng, B., Blankenberg, S., Nedelmann, M., Steinbrecher, A., Andres, F., Rosenkranz, M., Sinning, C., Schnabel, R. B. & Gerloff, C., 09.09.2021, In: STROKE. 53, 1, p. 177-184 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Game-theoretical mapping of fundamental brain functions based on lesion deficits in acute stroke
Malherbe, C., Cheng, B., Königsberg, A., Cho, T-H., Ebinger, M., Endres, M., Fiebach, J. B., Fiehler, J., Galinovic, I., Puig, J., Thijs, V., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Wouters, A., Gerloff, C., Hilgetag, C. C. & Thomalla, G., 02.09.2021, In: BRAIN COMMUN. 3, 3, p. fcab204Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fahrtauglichkeit bei Parkinson-Erkrankung
Buhmann, C., 01.09.2021, In: Neurologie up2date. 2021, 2, p. 327-339 4.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Correction to: Cherry-picking the Wrong Patients?
Fiehler, J., Thomalla, G. & Bendszus, M., 09.2021, In: CLIN NEURORADIOL. 31, 3, p. 865Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Differential association of flow velocities in the carotid artery with plaques, intima media thickness and cardiac function
Rimmele, D. L., Borof, K., Wenzel, J-P., Jensen, M., Behrendt, C-A., Waldeyer, C., Schnabel, R. B., Zeller, T., Debus, E. S., Blankenberg, S., Gerloff, C. & Thomalla, G., 09.2021, In: ATHEROSCLEROSIS PLUS. 43, p. 18-23 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intact procedural learning and motor intracortical inhibition in adult neurofibromatosis type 1 gene carriers
Germanidis, E. I., Schulz, R., Quandt, F., Mautner, V. F., Gerloff, C. & Timmermann, J. E., 09.2021, In: CLIN NEUROPHYSIOL. 132, 9, p. 2037-2045 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Modeling the Optimal Transportation for Acute Stroke Treatment: Impact of Diurnal Variations in Traffic Rate
Ernst, M., Psychogios, M-N., Schlemm, E., Holodinsky, J. K., Kamal, N., Rodt, T., Henningsen, H., Kraemer, C., Thomalla, G., Fiehler, J. & Brekenfeld, C., 09.2021, In: CLIN NEURORADIOL. 31, 3, p. 729-736 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Serum neurofilament is associated with motor function, cognitive decline and subclinical cardiac damage in advanced Parkinson's disease (MARK-PD)
Niemann, L., Lezius, S., Maceski, A., Leppert, D., Englisch, C., Schwedhelm, E., Zeller, T., Gerloff, C., Kuhle, J. & Choe, C-U., 09.2021, In: PARKINSONISM RELAT D. 90, p. 44-48 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sphingosine-1-Phosphate, Motor Severity, and Progression in Parkinson's Disease (MARK-PD)
Schwedhelm, E., Englisch, C., Niemann, L., Lezius, S., von Lucadou, M., Marmann, K., Böger, R., Peine, S., Daum, G., Gerloff, C. & Choe, C-U., 09.2021, In: MOVEMENT DISORD. 36, 9, p. 2178-2182 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Author Correction: Phenotyping spinal abnormalities in patients with Neurofibromatosis type 1 using whole-body MRI
Well, L., Careddu, A., Stark, M., Farschtschi, S., Bannas, P., Adam, G., Mautner, V-F. & Salamon, J., 30.08.2021, In: SCI REP-UK. 11, 1, p. 17669Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Serious Adverse Events and Their Impact on Functional Outcome in Acute Ischemic Stroke in the WAKE-UP Trial
Lettow, I., Jensen, M., Schlemm, E., Boutitie, F., Quandt, F., Cheng, B., Ebinger, M., Endres, M., Fiebach, J. B., Thijs, V., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Gerloff, C., Thomalla, G. & WAKE-UP Investigators, 26.08.2021, In: STROKE. 2021, 52, p. 3768–3776 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Profiles of patients' self-reported health after acute stroke
Rimmele, D. L., Schrage, T., Lebherz, L., Kriston, L., Gerloff, C., Härter, M. & Thomalla, G., 23.08.2021, In: Neurol Res Pract. 3, 1, p. 43Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Imaging Evaluation of Plexiform Neurofibromas in Neurofibromatosis Type 1: A Survey-Based Assessment
Ahlawat, S., Ly, K. I., Fayad, L. M., Fisher, M. J., Lessing, A. J., Berg, D. J., Salamon, J. M., Mautner, V-F., Babovic-Vuksanovic, D., Dombi, E., Harris, G., Plotkin, S. R., Blakeley, J. & REiNS International Collaboration, 17.08.2021, In: NEUROLOGY. 97, 7 Suppl 1, p. S111-S119Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Delayed access to conscious processing in multiple sclerosis: Reduced cortical activation and impaired structural connectivity
Has Silemek, A. C., Ranjeva, J-P., Audoin, B., Heesen, C., Gold, S. M., Kühn, S., Weygandt, M. & Stellmann, J-P., 01.08.2021, In: HUM BRAIN MAPP. 42, 11, p. 3379-3395 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Welche Bildgebung zur Patientenauswahl für Thrombektomie in welchem Zeitfenster?
Cheng, B. & Broocks, G., 01.08.2021, In: NERVENARZT. 92, 8, p. 733-743 11 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
A case of Huntington's disease with two reduced penetrance alleles
Grimm, K., Zühlke, C., Gerloff, C. & Zittel, S., 08.2021, In: CLIN NEUROL NEUROSUR. 207, 106773.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HbA1c and Motor Outcome in Parkinson's Disease in the Mark-PD Study
Zittel, S., Uyar, M., Lezius, S., Gerloff, C. & Choe, C-U., 08.2021, In: MOVEMENT DISORD. 36, 8, p. 1991-1992 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Long-term prognostic counselling in people with multiple sclerosis using an online analytical processing tool
Kosch, R., Schiffmann, I., Daumer, M., Lederer, C., Scalfari, A., Galea, I., Scheiderbauer, J., Rahn, A. & Heesen, C., 08.2021, In: MULT SCLER J. 27, 9, p. 1442-1450 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Psychometric properties of a patient-reported outcome set in acute stroke patients
Philipp, R., Lebherz, L., Thomalla, G., Härter, M., Appelbohm, H., Frese, M. & Kriston, L., 08.2021, In: BRAIN BEHAV. 11, 8, p. e2249 e2249.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Thrombektomie beim Schlaganfall – von klinischen Studien zur täglichen Praxis
Thomalla, G. & Fiehler, J., 08.2021, In: NERVENARZT. 92, 8, p. 731-732 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
The Joint Vasculitis Registry in German-speaking countries (GeVas) - a prospective, multicenter registry for the follow-up of long-term outcomes in vasculitis
Iking-Konert, C., Wallmeier, P., Arnold, S., Adler, S., de Groot, K., Hellmich, B., Hoyer, B. F., Holl-Ulrich, K., Ihorst, G., Kaufmann, M., Kötter, I., Müller-Ladner, U., Magnus, T., Rech, J., Schubach, F., Schulze-Koops, H., Venhoff, N., Wiech, T., Villiger, P. & Lamprecht, P., 31.07.2021, In: BMC RHEUMATOL. 5, 1, 40.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multi-dimensional and longitudinal systems profiling reveals predictive pattern of severe COVID-19
Woo, M. S., Haag, F., Nierhaus, A., Jarczak, D., Roedl, K., Mayer, C., Brehm, T. T., van der Meirschen, M., Hennigs, A., Christopeit, M., Fiedler, W., Karagiannis, P., Burdelski, C., Schultze, A., Huber, S., Addo, M. M., Schmiedel, S., Friese, M. A., Kluge, S. & Schulze Zur Wiesch, J., 23.07.2021, In: ISCIENCE. 24, 7, p. 102752Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Case series of idiopathic intracranial hypertension in three patients with immune-complex glomerulonephritis
Fischbach, F., Scholz-Hehn, A. D., Gerloff, C. & Pötter-Nerger, M., 13.07.2021, In: BMC NEUROL. 21, 1, 278.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Calcipotriol Enhances Efficacy of Imatinib and Nilotinib on Cells Derived from Plexiform Neurofibroma
Zhao, Y., Yan, M., Mautner, V., Smeets, R., Gosau, M., Kluwe, L. & Friedrich, R. E., 07.2021, In: ANTICANCER RES. 41, 7, p. 3293-3298 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review